Guoyu Chen

Shanghai Cancer Institute

H指数:13

被引数:753

个人简介

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Targeting TRIM59 impairs RNA splicing and promotes neuroblastoma differentiation and therapeutic responses

靶向TRIM59损害RNA剪接并促进神经母细胞瘤分化和治疗反应

Journal of Experimental & Clinical Cancer Research

IF12.8

2025-12-180

OAAI

Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN

抑制嘌呤代谢促进由MYCN驱动的神经母细胞瘤分化

CANCER MEDICINE

IF3.1

2025-05-120

Pumpkin CmoCDPK20 improved the salt tolerance of grafted cucumber by phosphorylating CmoDREB2A to promote jasmonic acid biosynthesis and antioxidant enzyme activities

南瓜CmoCDPK20通过磷酸化CmoDREB2A来促进茉莉酸生物合成和抗氧化酶活性，从而提高了嫁接黄瓜的耐盐性。

PLANT JOURNAL

IF5.7

2025-05-100

PRE

GNAO1 overexpression promotes neural differentiation of glioma stem-like cells and reduces tumorigenicity through TRIM21/CREB/HES1 axis

过表达glnao1通过TRIM21/CREB/HES1轴促进胶质瘤干细胞样细胞神经分化并降低致瘤性

ONCOGENE

IF7.3

2024-11-230

PRE

c-Myc alone is enough to reprogram fibroblasts into functional macrophages

单独的c-myc足以将成纤维细胞重编程为功能性巨噬细胞

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2024-09-121

OAAI

Single-cell RNA transcriptomic analyses of tumor microenvironment of ovarian metastasis in gastric cancer

胃癌卵巢转移肿瘤微环境的单细胞RNA转录组学分析

CELLULAR ONCOLOGY

IF4.8

2024-08-200

PRE

ZBTB7A interferes with the RPL5-P53 feedback loop and reduces endoplasmic reticulum stress-induced apoptosis of pancreatic cancer cells

MOLECULAR CARCINOGENESIS

IF3.2

2024-06-190

PRE

TRIM24 Cooperates with Ras Mutation to Drive Glioma Progression through snoRNA Recruitment of PHAX and DNA-PKcs

TRIM24与Ras突变合作，通过snoRNA募集PHAX和dna-pkcs来推动神经胶质瘤的进展

ADVANCED SCIENCE

IF14.1

2024-06-030

OAAI

KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m6A reader YTHDC1 protein degradation

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

IF12.8

2024-05-143

OAAI

The critical role of CmCIPK1-CmRbohD1/D2 complexes in generating H2O2 signals for enhancing salt tolerance in pumpkin

HORTICULTURAL PLANT JOURNAL

IF6.2

2024-04-013

OAAI

LINC00115 promotes chemoresistant breast cancer stem-like cell stemness and metastasis through SETDB1/PLK3/HIF1α signaling

MOLECULAR CANCER

IF33.9

2024-03-228

OAAI

Pumpkin CmoDREB2A enhances salt tolerance of grafted cucumber through interaction with CmoNAC1 to regulate H2O2 and ABA signaling and K+/Na+ homeostasis

HORTICULTURE RESEARCH

IF8.5

2024-02-283

OAAI

USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer

CELL BIOLOGY AND TOXICOLOGY

IF5.9

2023-08-032

PRE

Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex

CELLULAR ONCOLOGY

IF4.8

2023-07-191

PRE

Gut microbial metabolite butyrate improves anticancer therapy by regulating intracellular calcium homeostasis

肠道微生物代谢产物丁酸通过调节细胞内钙稳态改善抗癌治疗

HEPATOLOGY

IF15.8

2023-01-0324

PRE

The essential role of jasmonate signaling in Solanum habrochaites rootstock-mediated cold tolerance in tomato grafts

HORTICULTURE RESEARCH

IF8.5

2022-10-1113

OAAI

Regulation of cohesin-mediated chromosome folding by PDS5 in mammals

PDS5对cohesin介导的哺乳动物染色体折叠的调控

EMBO REPORTS

IF6.2

2022-09-210

Mechanisms of linezolid resistance in Staphylococcus capitis with the novel mutation C2128T in the 23S rRNA gene in China

BMC MICROBIOLOGY

IF4.2

2022-08-209

OAAI

The precursor of PI(3,4,5)P3 alleviates aging by activating daf-18(Pten) and independent of daf-16

NATURE COMMUNICATIONS

IF15.7

2020-09-0820

OAAI

Three-dimensional facial-image analysis to predict heterogeneity of the human ageing rate and the impact of lifestyle

NATURE METABOLISM

IF20.8

2020-09-0749

PREAI

Guoyu Chen

个人简介

教育背景

工作经历

荣誉奖项

研究方向