未登录.png)
分享.png)
收藏Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/BAK hetero-complexes
Seiller, Carolane; Maiga, Sophie; Touzeau, Cyrille; Bellanger, Celine; Kervoelen, Charlotte; Descamps, Geraldine; Maillet, Laurent; Moreau, Philippe; Pellat-Deceunynck, Catherine; Gomez-Bougie, Patricia; Amiot, Martine 分享 收藏 The MYRACLE protocol study: a multicentric observational prospective cohort study of patients with multiple myelomaBenaniba, Lina; Tessoulin, Benoit; Trudel, Sabrina; Pellat-Deceunynck, Catherine; Amiot, Martine; Minvielle, Stephane; Gourraud, Pierre Antoine; de Visme, Sophie; Maisonneuve, Herve; Lok, Anne; Le Gouill, Steven; Moreau, Philippe; Touzeau, Cyrille 分享 收藏 Disruption of IRE1α through its kinase domain attenuates multiple myelomaHarnoss, Jonathan M.; Le Thomas, Adrien; Shemorry, Anna; Marsters, Scot A.; Lawrence, David A.; Lu, Min; Chen, Yung-Chia Ariel; Qing, Jing; Totpal, Klara; Kan, David; Segal, Ehud; Merchant, Mark; Reichelt, Mike; Wallweber, Heidi Ackerly; Wang, Weiru; Clark, Kevin; Kaufman, Susan; Beresini, Maureen H.; Laing, Steven T.; Sandoval, Wendy; Lorenzo, Maria; Wu, Jiansheng; Lyh, Justin; De Bruyn, Tom; Heidersbach, Amy; Haley, Benjamin; Gogineni, Alvin; Weimer, Robby M.; Lee, Dong; Braun, Marie-Gabrielle; Rudolph, Joachim; VanWyngarden, Michael J.; Sherbenou, Daniel W.; Gomez-Bougie, Patricia; Amiot, Martine; Acosta-Alvear, Diego; Walter, Peter; Ashkenazi, Avi 分享 收藏 CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophagesPapin, Antonin; Tessoulin, Benoit; Bellanger, Celine; Moreau, Anne; Le Bris, Yannick; Maisonneuve, Herve; Moreau, Philippe; Touzeau, Cyrille; Amiot, Martine; Pellat-Deceunynck, Catherine; Le Gouill, Steven; Chiron, David 分享 收藏 分享 收藏 Interactions between cancer-associated fibroblasts and tumor cells promote MCL-1 dependency in estrogen receptor-positive breast cancersLouault, K.; Bonneaud, T. L.; Seveno, C.; Gomez-Bougie, P.; Nguyen, F.; Gautier, F.; Bourgeois, N.; Loussouarn, D.; Kerdraon, O.; Barille-Nion, S.; Jezequel, P.; Campone, M.; Amiot, M.; Juin, P. P.; Souaze, F. 分享 收藏 分享 收藏 Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathwaysTessoulin, Benoit; Moreau-Aubry, Agnes; Descamps, Geraldine; Gomez-Bougie, Patricia; Maiga, Sophie; Gaignard, Alban; Chiron, David; Menoret, Emmanuelle; Le Gouill, Steven; Moreau, Philippe; Amiot, Martine; Pellat-Deceunynck, Catherine 分享 收藏 p53 regulates CD46 expression and measles virus infection in myeloma cellsLok, Anne; Descamps, Geraldine; Tessoulin, Benoit; Chiron, David; Eveillard, Marion; Godon, Catherine; Le Bris, Yannick; Vabret, Astrid; Bellanger, Celine; Maillet, Laurent; Barille-Nion, Sophie; Gregoire, Marc; Fonteneau, Jean-Francois; Le Gouill, Steven; Moreau, Philippe; Tangy, Frederic; Amiot, Martine; Moreau-Aubry, Agnes; Pellat-Deceunynck, Catherine 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Deep and sustained response after venetoclax therapy in a patient with very advanced refractory myeloma with translocationTouzeau, Cyrille; Le Gouill, Steven; Mahe, Beatrice; Boudreault, Jean Samuel; Gastinne, Thomas; Blin, Nicolas; Caillon, Helene; Dousset, Christelle; Amiot, Martine; Moreau, Philippe 分享 收藏 分享 收藏 分享 收藏 BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic miceHamouda, Mohamed-Amine; Jacquel, Arnaud; Robert, Guillaume; Puissant, Alexandre; Richez, Valentine; Cassel, Romeo; Fenouille, Nina; Roulland, Sandrine; Gilleron, Jerome; Griessinger, Emmanuel; Dubois, Alix; Bailly-Maitre, Beatrice; Goncalves, Diogo; Mallavialle, Aude; Colosetti, Pascal; Marchetti, Sandrine; Amiot, Martine; Gomez-Bougie, Patricia; Rochet, Nathalie; Deckert, Marcel; Avet-Loiseau, Herve; Hofman, Paul; Karsenti, Jean-Michel; Jeandel, Pierre-Yves; Blin-Wakkach, Claudine; Nadel, Bertrand; Cluzeau, Thomas; Anderson, Kenneth C.; Fuzibet, Jean-Gabriel; Auberger, Patrick; Luciano, Frederic 分享 收藏 Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma ModelsPunnoose, Elizabeth A.; Leverson, Joel D.; Peale, Franklin; Boghaert, Erwin R.; Belmont, Lisa D.; Tan, Nguyen; Young, Amy; Mitten, Michael; Ingalla, Ellen; Darbonne, Walter C.; Oleksijew, Anatol; Tapang, Paul; Yue, Peng; Oeh, Jason; Lee, Leslie; Maiga, Sophie; Fairbrother, Wayne J.; Amiot, Martine; Souers, Andrew J.; Sampath, Deepak 分享 收藏 The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells通过抑制骨髓瘤细胞中的缺氧诱导因子 (HIF)-1α 来增强来那度胺的体内抗肿瘤作用Storti, Paola; Toscani, Denise; Airoldi, Irma; Marchica, Valentina; Maiga, Sophie; Bolzoni, Marina; Fiorini, Elena; Campanini, Nicoletta; Martella, Eugenia; Mancini, Cristina; Guasco, Daniela; Ferri, Valentina; Donofrio, Gaetano; Aversa, Franco; Amiot, Martine; Giuliani, Nicola 分享 收藏 BH3 profiling identifies heterogeneous dependency on Bcl-2 family members in multiple myeloma and predicts sensitivity to BH3 mimeticsTouzeau, C.; Ryan, J.; Guerriero, J.; Moreau, P.; Chonghaile, T. N.; Le Gouill, S.; Richardson, P.; Anderson, K.; Amiot, M.; Letai, A. 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
