José I. Borrell - Publications, H-index & Citations

José I. Borrell

consejo superior de investigaciones cientificas (csic)

41H指数

307论文数

6.8K被引数

收录论文 77

发表时间

Rational Method for Structural Simplification as Key Step in Hit Discovery: The Case of FGFR2 and IGF1R Dual Inhibitors 基于理性的结构简化方法作为先导化合物发现中的关键步骤：FGFR2和IGF1R双重抑制剂的案例

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-05-07

OAAI

Torres-Urtizberea, Endika; Borrell, Jose I.; de la Bellacasa, Raimon Puig; Estrada-Tejedor, Roger

The Use of a Penta-Deuterophenyl Substituent to Improve the Metabolic Stability of a Tyrosine Kinase Inhibitor

MOLECULES

IF4.6

2024-12-22

OAAI

Dulsat, Julia; de la Bellacasa, Raimon Puig; Borrell, Jose I.

Design and functional characterization of a first-in-class irreversible inhibitor of HOIL-1-interacting protein (HOIP) with selective antitumor activity against B-cell non-Hodgkin lymphoma

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Gorjon de Pablo, G.; Montagut, A. M.; Armengol, M.; Combes-Soia, L.; Burlet-Schiltz, O.; Profitos-Peleja, N.; Fernandez-Serrano, M.; Farres, J.; Lutz, P. G.; Estrada-Tejedor, R.; Borrell, J. I.; Roue, G.

The MNK inhibitor EB1 sensitizes AR-V7 positive castration-resistant prostate cancer to enzalutamidee

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Garcia-Ortega, Sara; Suarez-Cabrera, Leticia; Morote, Joan; Mendez, Olga; Cano-Galietero, Marta; Muro-Blanc, Elena; Borrell, Jose I.; Santamaria, Anna; Ramon y Cajal, Santiago; Hummer, Stefan

When Unsuspected Crystallinity Ruins Biological Testing in Early Discovery: A Case Study

PHARMACEUTICALS

IF4.8

2024-02-22

OAAI

de Rocafiguera, Claudi; Belsa, Blanca; Font-Bardia, Merce; Puigjaner, Cristina; Serra, Eduard; Cuartero-Albesa, Ana M.; Puig de la Bellacasa, Raimon; Borrell, Jose I.

Synthesis of Chalcones: An Improved High-Yield and Substituent-Independent Protocol for an Old Structure

MOLECULES

IF4.6

2023-11-14

OAAI

Donaire-Arias, Ana; Poulsen, Martin L.; Ramon-Costa, Jaime; Montagut, Ana Maria; Estrada-Tejedor, Roger; Borrell, Jose I.

Post-ischemic reorganization of sensory responses in cerebral cortex

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-06-02

OAAI

Hayley, P.; Tuchek, C.; Dalla, S.; Borrell, J.; Murphy, M. D.; Nudo, R. J.; Guggenmos, D. J.

Design and functional characterization of a first-in-class irreversible inhibitor of HOIL-1-interacting protein (HOIP) with selective antitumor activity against B-cell non-Hodgkin lymphoma

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Montagut, Ana Maria; Cubillos, Marc Antoni Armengol; Gorjon-de-Pablo, Gema; Farres, Judith; Garcia, Laia Huguet; Profitos-Peleja, Nuria; Santos, Juliana Carvalho; Ribeiro, Marcelo Lima; Fernandez-Serrano, Miranda; Tejedor, Roger Estrada; Borrell, Jose I.; Roue, Gaël

Evaluation of Free Online ADMET Tools for Academic or Small Biotech Environments

MOLECULES

IF4.6

2023-01-12

OAAI

Dulsat, Julia; Lopez-Nieto, Blanca; Estrada-Tejedor, Roger; Borrell, Jose I.

Recent advances in the pharmacological targeting of ubiquitin-regulating enzymes in cancer

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2022-12-01

OAAI

Maria Montagut, Ana; Armengol, Marc; Gorjon de Pablo, Gema; Estrada-Tejedor, Roger; Ignacio Borrell, Jose; Roue, Gael

Deconstructing Markush: Improving the R&D Efficiency Using Library Selection in Early Drug Discovery

PHARMACEUTICALS

IF4.8

2022-09-18

OAAI

Manen-Freixa, Leticia; Borrell, Jose, I; Teixido, Jordi; Estrada-Tejedor, Roger

Overcoming Paradoxical Kinase Priming by a Novel MNK1 Inhibitor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-04-13

OAAI

Bou-Petit, Elisabeth; Hummer, Stefan; Alarcon, Helena; Slobodnyuk, Konstantin; Cano-Galietero, Marta; Fuentes, Pedro; Guijarro, Pedro J.; Jose Munoz, Maria; Suarez-Cabrera, Leticia; Santamaria, Anna; Estrada-Tejedor, Roger; Borrell, Jose, I; Ramon y Cajal, Santiago

1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications 1h-吡唑并 [3，4-b] 吡啶: 合成和生物医学应用

MOLECULES

IF4.6

2022-03-30

OAAI

Donaire-Arias, Ana; Montagut, Ana Maria; Puig de la Bellacasa, Raimon; Estrada-Tejedor, Roger; Teixido, Jordi; Borrell, Jose I.

Expanding the Diversity at the C-4 Position of Pyrido[2,3-d]pyrimidin-7(8H)-ones to Achieve Biological Activity against ZAP-70

PHARMACEUTICALS

IF4.8

2021-12-15

OAAI

Masip, Victor; Lirio, Angel; Sanchez-Lopez, Albert; Cuenca, Ana B.; Puig de la Bellacasa, Raimon; Abrisqueta, Pau; Teixido, Jordi; Borrell, Jose, I; Gibert, Albert; Estrada-Tejedor, Roger

1,6-Naphthyridin-2(1H)-ones: Synthesis and Biomedical Applications

PHARMACEUTICALS

IF4.8

2021-10-09

OAAI

Marcos Oliveras, Juan; Puig de la Bellacasa, Raimon; Estrada-Tejedor, Roger; Teixido, Jordi; Borrell, Jose, I

Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications

MOLECULES

IF4.6

2019-11-16

OAAI

Jubete, Guillem; Puig de la Bellacasa, Raimon; Estrada-Tejedor, Roger; Teixido, Jordi; Borrell, Jose I.

Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma

HAEMATOLOGICA

IF7.9

2018-06-28

OAAI

Recasens-Zorzo, Clara; Cardesa-Salzmann, Teresa; Petazzi, Paolo; Ros-Blanco, Laia; Esteve-Arenys, Anna; Clot, Guillem; Guerrero-Hernandez, Martina; Rodriguez, Vanina; Soldini, Davide; Valera, Alexandra; Moros, Alexandra; Climent, Fina; Gonzalez-Barca, Eva; Mercadal, Santiago; Arenillas, Leonor; Calvo, Xavier; Mate, Jose Luis; Gutierrez-Garcia, Gonzalo; Casanova, Isolda; Mangues, Ramon; Sanjuan-Pla, Alejandra; Bueno, Clara; Menendez, Pablo; Martinez, Antonio; Colomer, Dolors; Estrada Tejedor, Roger; Teixido, Jordi; Campo, Elias; Lopez-Guillermo, Armando; Ignacio Borrell, Jose; Colomo, Luis; Perez-Galan, Patricia; Roue, Gael

Pharmacological modulation of CXCL12-CXCR4 intracellular trafficking potentiates the in vitro and in vivo activity of the BET bromodomain inhibitor CPI203 in diffuse large B-cell lymphoma

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Recasens-Zorzo, Clara; Cardesa-Salzmann, Teresa; Ros-Blanco, Laia; Esteve-Arenys, Anna; Clot, Guillem; Guerrero-Hernandez, Martina; Valera, Alejandra; Moros, Alejandra; Gutierrez, Gonzalo; Casanova, Isolda; Mangues, Ramon; Sanjuan, Alejandra; Menendez, Pablo; Rodriguez, Vanina; Martinez, Antonio; Jares, Pedro; Colomer, Dolors; Teixido, Jordi; Borrell, Jose Ignacio; Campo, Elias; Lopez-Guillermo, Armando; Colomo, Luis; Perez-Galan, Patricia; Roue, Gael

Stable 5,5′-Substituted 2,2′-Bipyrroles: Building Blocks for Macrocyclic and Materials Chemistry

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2017-06-08

PREAI

Anguera, Gonzalo; Kauffmann, Brice; Borrell, Jose I.; Borros, Salvador; Sanchez-Garcia, David

Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2017-03-31

OAAI

Balsas, P.; Esteve-Arenys, A.; Roldan, J.; Jimenez, L.; Rodriguez, V.; Valero, J. G.; Chamorro-Jorganes, A.; de la Bellacasa, R. Puig; Teixido, J.; Matas-Cespedes, A.; Moros, A.; Martinez, A.; Campo, E.; Saez-Borderias, A.; Borrell, J. I.; Perez-Galan, P.; Colomer, D.; Roue, G.

研究方向