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The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse 从头DNA甲基转移酶3B是MYC在多发性骨髓瘤中的新型表观遗传调控因子，代表了一个有前景的治疗靶点以对抗复发。 Muylaert, Catharina; Van Hemelrijck, Lien Ann; Van der Vreken, Arne; Heestermans, Robbe; Satilmis, Hatice; Verheye, Emma; Alaterre, Elina; Olsen, Catharina; De Beule, Nathan; De Veirman, Kim; Menu, Eline; Vanderkerken, Karin; Moreaux, Jerome; De Bruyne, Elke 分享 收藏
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Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction Ironomycin通过靶向铁代谢依赖性诱导套细胞淋巴瘤细胞死亡 Ovejero, Sara; Alibert, Laura; Devin, Julie; Caneque, Tatiana; Jacquier, Valentin; Romero, Andrea; Amar, Salome; Abouladze, Matthieu; Paco, Elvira Garcia de; Gadacha, Ouissem Karmous; Requirand, Guilhem; Robert, Nicolas; Zellagui, Miss Leriem; de Boussac, Hugues; Cartron, Guillaume; Chiche, Johanna; Ricci, Jean-Ehrland; Herbaux, Charles; Rodriguez, Raphael; Moreaux, Jerome; Bret, Caroline 分享 收藏
Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens Ueda, Natsuko; Cahen, Marine; Leonard, Jenny; Deleurme, Laurent; Dreano, Stephane; Sirac, Christophe; Galy, Anne; Moreaux, Jerome; Danger, Yannic; Cogne, Michel 分享 收藏
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FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population Constantinides, Michael; Robert, Nicolas; Multrier, Caroline; Coenon, Lois; Campos-Mora, Mauricio; Jacquard, Carine; Gao, Fei; Zemiti, Sara; Presumey, Jessy; Cartron, Guillaume; Moreaux, Jerome; Villalba, Martin 分享 收藏
MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling Techer, Herve; Gopaul, Diyavarshini; Heuze, Jonathan; Bouzalmad, Nail; Leray, Baptiste; Vernet, Audrey; Mettling, Clement; Moreaux, Jerome; Pasero, Philippe; Lin, Yea-Lih 分享 收藏
An atlas of cells in the human tonsil Massoni-Badosa, Ramon; Aguilar-Fernandez, Sergio; Nieto, Juan C.; Soler-Vila, Paula; Elosua-Bayes, Marc; Marchese, Domenica; Kulis, Marta; Vilas-Zornoza, Amaia; Buhler, Marco Matteo; Rashmi, Sonal; Alsinet, Clara; Caratu, Ginevra; Moutinho, Catia; Ruiz, Sara; Lorden, Patricia; Lunazzi, Giulia; Colomer, Dolors; Frigola, Gerard; Blevins, Will; Romero-Rivero, Lucia; Jimenez-Martinez, Victor; Vidal, Anna; Mateos-Jaimez, Judith; Maiques-Diaz, Alba; Ovejero, Sara; Moreaux, Jerome; Palomino, Sara; Gomez-Cabrero, David; Agirre, Xabier; Weniger, Marc A.; King, Hamish W.; Garner, Lucy C.; Marini, Federico; Cervera-Paz, Francisco Javier; Baptista, Peter M.; Vilaseca, Isabel; Rosales, Cecilia; Ruiz-Gaspa, Silvia; Talks, Benjamin; Sidhpura, Keval; Pascual-Reguant, Anna; Hauser, Anja E.; Haniffa, Muzlifah; Prosper, Felipe; Kueppers, Ralf; Gut, Ivo Glynne; Campo, Elia; Martin-Subero, Jose Ignacio; Heyn, Holger 分享 收藏
Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma Bruyer, Angelique; Dutrieux, Laure; de Boussac, Hugues; Martin, Thibaut; Chemlal, Djamila; Robert, Nicolas; Requirand, Guilhem; Cartron, Guillaume; Vincent, Laure; Herbaux, Charles; Lutzmann, Malik; Bret, Caroline; Pasero, Philippe; Moreaux, Jerome; Ovejero, Sara 分享 收藏
RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma Emde-Rajaratnam, Martina; Beck, Susanne; Benes, Vladimir; Salwender, Hans; Bertsch, Uta; Scheid, Christoph; Haenel, Mathias; Weisel, Katja; Hielscher, Thomas; Raab, Marc S.; Goldschmidt, Hartmut; Jauch, Anna; Maes, Ken; De Bruyne, Elke; Menu, Eline; De Veirman, Kim; Moreaux, Jerome; Vanderkerken, Karin; Seckinger, Anja; Hose, Dirk 分享 收藏
EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma Chemlal, Djamila; Varlet, Emmanuel; Machura, Amelie; Ovejero, Sara; Requirand, Guilhem; Robert, Nicolas; Cartron, Guillaume; Alaterre, Elina; Bret, Caroline; Vincent, Laure; Herbaux, Charles; Cavalli, Giacomo; Bruyer, Angelique; De Boussac, Hugues; Moreaux, Jerome 分享 收藏
S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma Wang, Yanmeng; Muylaert, Catharina; Wyns, Arne; Vlummens, Philip; De Veirman, Kim; Vanderkerken, Karin; Zaal, Esther; Berkers, Celia; Moreaux, Jerome; De Bruyne, Elke; Menu, Eline 分享 收藏
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