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I

Isabel Leroux-Roels

center for vaccinology
H指数:34
被引数:6,352

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A Phase 1/2 Trial Evaluating the Safety and Immunogenicity of an mRNA-based Seasonal Influenza Vaccine Candidate Encoding Hemagglutinin and Neuraminidase

评价编码血凝素和神经氨酸酶的mRNA基季节性流感疫苗候选药物安全性和免疫原性的1/2期临床试验

Infectious Diseases and Therapy
IF5.3
2026-10-150
OAAI
Ilse De Coster; Jose F. Cardona; Murdo Ferguson; Isabel Leroux-Roels; Haylene Nell; Stefano Berrè; Sonia Schoonbroodt; Clarisse Lorin; Leroy Jide Ovbude; Brian Moldt
A randomised, double-blind, placebo-controlled phase I clinical trial to evaluate the safety, tolerability and immunogenicity of three doses of an adjuvanted group B Streptococcus vaccine in older adults aged 55 to 75

一项随机、双盲、安慰剂对照的I期临床试验，旨在评估55至75岁老年人接种三种剂量的佐剂化B群链球菌疫苗的安全性、耐受性和免疫原性

Vaccine
IF3.5
2026-09-180
OAAI
Lidia Oostvogels; Azhar Alhatemi; Simon De Gussem; Ebbe Englev; Per B. Fischer; Bart Jacobs; Bengt Johansson-Lindbom; Geoff Kitson; Gwenn Waerlop; Isabel Leroux-Roels
Correction: Leroux-Roels et al. Immunogenicity and Safety of the ExPEC9V Escherichia coli Vaccine Co-Administered with a High-Dose Influenza Vaccine in Older Adults: A Placebo-Controlled, Randomized, Phase 3 Study. Vaccines 2026, 14, 146

更正：Leroux-Roels 等人。ExPEC9V 大肠杆菌疫苗与高剂量流感疫苗联合接种在老年人中的免疫原性和安全性：一项安慰剂对照、随机、III 期研究。Vaccines 2026, 14, 146

Vaccines
IF3.4
2026-08-050
OAAI
Isabel Leroux-Roels; Tracey A. Day; Sofie Deleu; Chelsea McLean; Oscar Go; Todd A. Davies; Jeroen N. Stoop; Monika Peeters; Maria G. Pau; Bart Spiessens; Michal Sarnecki
Safety and immunogenicity of an investigational mRNA-lipid nanoparticle-based monovalent influenza vaccine: Results from a phase 1, randomized, dose-escalation study

一种试验性mRNA-脂质纳米颗粒为基础的单价流感疫苗的安全性和免疫原性：来自一项1期、随机、剂量递增研究的结果

Human Vaccines & Immunotherapeutics
IF0
2026-05-230
PRE
Leroux-Roels, Isabel; De Coster, Ilse; Borobia, Alberto M.; Langley, Joanne M.; Ochoa Mazarro, Dolores; Ruiz-Antoran, Belen; Berre, Stefano; Germain, Sophie; Knauer, Christine; Koch, Sven D.; Mann, Philipp; Mesia Vela, Doris; Ovbude, Leroy Jide; Pardo, Iris Alessandra; Srivastava, Barkha; Moldt, Brian; Nordgren, Marcus
A standardized workflow for typing S. marcescens outbreaks using FT-IR spectroscopy

使用FT-IR光谱法对S. marcescens暴发进行分型的标准化工作流程

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
IF3
2026-05-010
OA
Passaris, Ioannis; Van Goethem, Sam; Crombe, Florence; Hamerlinck, Hannelore; Desmet, Stefanie; Naesens, Reinout; Willems, Philippe; De Geyter, Deborah; Leroux-Roels, Isabel; Glupczynski, Youri; Malhotra-Kumar, Surbhi; Goossens, Herman; Ceyssens, Pieter-Jan
A Novel Carbohydrate Fatty-Acid Monosulphate Ester, Squalane-in-Water Adjuvant Is Safe and Enhances Inactivated Influenza Vaccine Immunogenicity in Older Adults

一种新型碳水化合物脂肪酸单硫酸酯，角鲨烷-水佐剂安全且能增强老年人群灭活流感疫苗的免疫原性

Vaccines
IF3.4
2026-03-030
OAAI
Valentino D’Onofrio; Bart Jacobs; Azhar Alhatemi; Simon De Gussem; Marjolein Verstraete; Sharon Porrez; Anthony Willems; Fien De Boever; Gwenn Waerlop; Geert Leroux-Roels; Els Michels; Francesca Vanni; Alessandro Manenti; Peter Paul Platenburg; Luuk Hilgers; Isabel Leroux-Roels
A first-in-human Phase 1/1b randomized trial evaluating the safety and immunogenicity of a respiratory syncytial virus (RSV) virus-like particle subunit vaccine (IVX-121) in healthy young and older adults

一项首次人体I/1b期随机试验，评估呼吸道合胞病毒（RSV）病毒样颗粒亚单位疫苗（IVX-121）在健康年轻和老年成人中的安全性和免疫原性。

Human Vaccines and Immunotherapeutics
IF3.5
2026-03-030
OA
Ilse De Coster; Isabel Leroux-Roels; Kanchanamala Withanage; Leen Suykens; Valentino D’Onofrio; Geert Leroux-Roels; Pierre van Damme; Max Ciarlet; Elizabeth M. Adams; Wasima Rida; Judy Wen; Margaret MacDonald; Jennifer Price; Niranjan Kanesa-thasan
Immunogenicity and Safety of Co-administration of Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine With 20-Valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years: A Randomized, Non-inferiority Trial

在≥60岁成人中佐剂呼吸道合胞病毒前融合F蛋白疫苗与20价肺炎球菌结合疫苗联合接种的免疫原性和安全性：一项随机非劣效性试验

Clinical Infectious Diseases
IF7.3
2026-01-010
PRE
Isabel Leroux‐Roels; Muriel Lins; Ronald Surowitz; Antoinette Pragalos; Paulia Kwo Ton Ge Jua; Dominique Wauters; Amulya Jayadev; Jacqueline Elaine Akite; Archana M. Jastorff; Vicky Cárdenas; Marie Van der Wielen; the RSV-019 study group; Abram H. Burgher; Adeyemi Gbohunmi; Agnieszka Jurek-Urbanowska; Bruce M. Rankin; Carlos Brotons Cuixart; Ewa Krecipro Nizinska; Fernando Cereto Castro; Jay Sandberg; Jean Benoit Martinot; Joseph Soufer; Katarzyna Wawrzyniec-Lis; Kathleen Jones; Klaas Vercruysse; Lina Perez Breva; Luc Capiau; Magda Dabrowska; Manuchehr Darani; Miguel Trevino; Patrick Dennis; Patrick H. P. Soentjens; Przemysław Borowy; Rachel M. Presti; Rica Santiago; Salma Saiger; Sander Gothard; Shital Upadhyay; Tatyana Miroshnikova; William Nixon; Madhavi Ampajwala
AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells

AS04通过增强树突状细胞的NOTCH信号和记忆B细胞的增殖，驱动更优的交叉保护性抗体应答

Frontiers in Immunology
IF5.9
2025-07-260
OA
Valentino D’Onofrio; AnaCarolina Santana; Marthe Pauwels; Gwenn Waerlop; Anthony Willems; Fien De Boever; Martin Müller; Peter Sehr; Tim Waterboer; Isabel Leroux-Roels; Ashish A. Sharma; Rafick Pierre Sékaly; Geert Leroux-Roels
Efficacy, safety, and immunogenicity of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) in older adults over three respiratory syncytial virus seasons (AReSVi-006): a multicentre, randomised, observer-blinded, placebo-controlled, phase 3 trial

AS01E佐剂呼吸道合胞病毒前融合F蛋白疫苗（RSVPreF3 OA）在老年人群中的有效性、安全性和免疫原性研究（跨越三个呼吸道合胞病毒流行季）（AReSVi-006）：一项多中心、随机、观察者设盲、安慰剂对照的III期临床试验

The Lancet Respiratory Medicine
IF0
2025-04-140
PRE
Michael G Ison; Alberto Papi; Eugene Athan; Robert G Feldman; Joanne M Langley; Dong-Gun Lee; Isabel Leroux-Roels; Federico Martinon-Torres; Tino F Schwarz; Richard N van Zyl-Smit; Susanna Cuadripani; Quentin Deraedt; Nancy Dezutter; Catherine Gerard; Laurence Fissette; Stebin Xavier; Marie-Pierre David; Aurélie Olivier; Marie Van der Wielen; Dominique Descamps; Manuel Zocco
Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against Rift Valley fever in healthy adults: a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial
LANCET INFECTIOUS DISEASES
IF31
2024-11-011
PRE
Leroux-Roels, Isabel; Prajeeth, Chittappen Kandiyil; Aregay, Amare; Nair, Niranjana; Rimmelzwaan, Guus F.; Osterhaus, Albert D. M. E.; Kardinahl, Simone; Pelz, Sabrina; Bauer, Stephan; D'Onofrio, Valentino; Alhatemi, Azhar; Jacobs, Bart; De Boever, Fien; Porrez, Sharon; Waerlop, Gwenn; Punt, Carine; Hendriks, Bart; von Mauw, Ellemieke; van de Water, Sandra; Harders-Westerveen, Jose; Rockx, Barry; van Keulen, Lucien; Kortekaas, Jeroen; Leroux-Roels, Geert; Schreur, Paul J. Wichgers
Safety and Immunogenicity of a Carbohydrate Fatty Acid Monosulphate Ester Adjuvant Combined with a Low-Dose Quadrivalent Split-Virion Inactivated Influenza Vaccine: A Randomised, Observer-Blind, Active-Controlled, First-in-Human, Phase 1 Study
VACCINES
IF3.4
2024-09-101
OAAI
D'Onofrio, Valentino; Porrez, Sharon; Jacobs, Bart; Alhatemi, Azhar; De Boever, Fien; Waerlop, Gwenn; Michels, Els; Vanni, Francesca; Manenti, Alessandro; Leroux-Roels, Geert; Platenburg, Peter Paul; Hilgers, Luuk; Leroux-Roels, Isabel

研究方向

暂未获取到该数据
G
Geert Leroux‐Roels
H 指数:67论文数:467被引数:1.6万
G
Gwenn Waerlop
H 指数:9论文数:20被引数:335
F
Fien De Boever
H 指数:11论文数:35被引数:783
A
Azhar Alhatemi
H 指数:4论文数:17被引数:162
J
Jerina Boelens
H 指数:30论文数:127被引数:4,266
B
Bruno Verhasselt
H 指数:38论文数:207被引数:5,345
V
Valentino D’Onofrio
H 指数:12论文数:39被引数:465
J
Joanne M. Langley
H 指数:64论文数:412被引数:1.3万
F
Frédéric Clément
H 指数:24论文数:77被引数:3,146
Y
Yorick Janssens
H 指数:15论文数:57被引数:934