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I

Isabel Leroux‐Roels

Ghent University Hospital

34H指数
129论文数
6.2K被引数
收录论文 65
发表时间
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A randomised, double-blind, placebo-controlled phase I clinical trial to evaluate the safety, tolerability and immunogenicity of three doses of an adjuvanted group B Streptococcus vaccine in older adults aged 55 to 75一项随机、双盲、安慰剂对照的I期临床试验，旨在评估55至75岁老年人接种三种剂量的佐剂化B群链球菌疫苗的安全性、耐受性和免疫原性
errVaccine
IF3.5
err2026-09-18
err0
errOAAI
errLidia Oostvogels; Azhar Alhatemi; Simon De Gussem; Ebbe Englev; Per B. Fischer; Bart Jacobs; Bengt Johansson-Lindbom; Geoff Kitson; Gwenn Waerlop; Isabel Leroux-Roels
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Correction: Leroux-Roels et al. Immunogenicity and Safety of the ExPEC9V Escherichia coli Vaccine Co-Administered with a High-Dose Influenza Vaccine in Older Adults: A Placebo-Controlled, Randomized, Phase 3 Study. Vaccines 2026, 14, 146更正：Leroux-Roels 等人。ExPEC9V 大肠杆菌疫苗与高剂量流感疫苗联合接种在老年人中的免疫原性和安全性：一项安慰剂对照、随机、III 期研究。Vaccines 2026, 14, 146
errVaccines
IF3.4
err2026-08-05
err0
errOAAI
errIsabel Leroux-Roels; Tracey A. Day; Sofie Deleu; Chelsea McLean; Oscar Go; Todd A. Davies; Jeroen N. Stoop; Monika Peeters; Maria G. Pau; Bart Spiessens; Michal Sarnecki
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Safety and immunogenicity of an investigational mRNA-lipid nanoparticle-based monovalent influenza vaccine: Results from a phase 1, randomized, dose-escalation study一种试验性mRNA-脂质纳米颗粒为基础的单价流感疫苗的安全性和免疫原性：来自一项1期、随机、剂量递增研究的结果
errHuman Vaccines & Immunotherapeutics
IF0
err2026-05-23
err0
PREAI
errLeroux-Roels, Isabel; De Coster, Ilse; Borobia, Alberto M.; Langley, Joanne M.; Ochoa Mazarro, Dolores; Ruiz-Antoran, Belen; Berre, Stefano; Germain, Sophie; Knauer, Christine; Koch, Sven D.; Mann, Philipp; Mesia Vela, Doris; Ovbude, Leroy Jide; Pardo, Iris Alessandra; Srivastava, Barkha; Moldt, Brian; Nordgren, Marcus
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A standardized workflow for typing S. marcescens outbreaks using FT-IR spectroscopy使用FT-IR光谱法对S. marcescens暴发进行分型的标准化工作流程
errEUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
IF3
err2026-05-01
err0
errOAAI
errPassaris, Ioannis; Van Goethem, Sam; Crombe, Florence; Hamerlinck, Hannelore; Desmet, Stefanie; Naesens, Reinout; Willems, Philippe; De Geyter, Deborah; Leroux-Roels, Isabel; Glupczynski, Youri; Malhotra-Kumar, Surbhi; Goossens, Herman; Ceyssens, Pieter-Jan
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A Novel Carbohydrate Fatty-Acid Monosulphate Ester, Squalane-in-Water Adjuvant Is Safe and Enhances Inactivated Influenza Vaccine Immunogenicity in Older Adults一种新型碳水化合物脂肪酸单硫酸酯，角鲨烷-水佐剂安全且能增强老年人群灭活流感疫苗的免疫原性
errVaccines
IF3.4
err2026-03-03
err0
errOAAI
errValentino D’Onofrio; Bart Jacobs; Azhar Alhatemi; Simon De Gussem; Marjolein Verstraete; Sharon Porrez; Anthony Willems; Fien De Boever; Gwenn Waerlop; Geert Leroux-Roels; Els Michels; Francesca Vanni; Alessandro Manenti; Peter Paul Platenburg; Luuk Hilgers; Isabel Leroux-Roels
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A first-in-human Phase 1/1b randomized trial evaluating the safety and immunogenicity of a respiratory syncytial virus (RSV) virus-like particle subunit vaccine (IVX-121) in healthy young and older adults一项首次人体I/1b期随机试验，评估呼吸道合胞病毒（RSV）病毒样颗粒亚单位疫苗（IVX-121）在健康年轻和老年成人中的安全性和免疫原性。
errHuman Vaccines and Immunotherapeutics
IF3.5
err2026-03-03
err0
errOAAI
errIlse De Coster; Isabel Leroux-Roels; Kanchanamala Withanage; Leen Suykens; Valentino D’Onofrio; Geert Leroux-Roels; Pierre van Damme; Max Ciarlet; Elizabeth M. Adams; Wasima Rida; Judy Wen; Margaret MacDonald; Jennifer Price; Niranjan Kanesa-thasan
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Immunogenicity and Safety of the ExPEC9V Escherichia coli Vaccine Co-Administered with a High-Dose Influenza Vaccine in Older Adults: A Placebo-Controlled, Randomized, Phase 3 Study
errVaccines
IF3.4
err2026-01-31
err0
errOAAI
errIsabel Leroux-Roels; Tracey A. Day; Sofie Deleu; Chelsea McLean; Oscar Go; Todd A. Davies; Jeroen N. Stoop; Monika Peeters; Maria G. Pau; Bart Spiessens; Michal Sarnecki; Keira A. Cohen; on behalf of E.ngage Study Team
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Paced immune activation by AS04 drives superior cross-protective antibody response in Cervarix
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errD'Onofrio, Valentino; Willems, Anthony; Santana, Ana Carolina; Pauwels, Marthe; Waerlop, Gwenn; Leroux-Roels, Isabel; Sekaly, Rafick P.; Leroux-Roels, Geert G.
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Improving ventilation hygiene in wards for immunocompromised patients: a workflow comparison of traditional and innovative duct cleaning methods提高免疫抑制病房通风卫生：传统与创新风管清洁方法的流程比较
errINFECTION PREVENTION IN PRACTICE
IF0
err2025-09-01
err0
errOAAI
errDe Waegemaeker, Pascal; Snoeij, Thomas; Leroux-Roels, Isabel
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AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cellsAS04通过增强树突状细胞的NOTCH信号和记忆B细胞的增殖，驱动更优的交叉保护性抗体应答
errFrontiers in Immunology
IF5.9
err2025-07-26
err0
errOAAI
errValentino D’Onofrio; AnaCarolina Santana; Marthe Pauwels; Gwenn Waerlop; Anthony Willems; Fien De Boever; Martin Müller; Peter Sehr; Tim Waterboer; Isabel Leroux-Roels; Ashish A. Sharma; Rafick Pierre Sékaly; Geert Leroux-Roels
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Enhanced influenza vaccination for older adults in Europe: a review of the current situation and expert recommendations for the future欧洲老年人流感疫苗接种增强：当前状况综述及未来专家建议
errEXPERT REVIEW OF VACCINES
IF4.8
err2025-05-09
err0
errOAAI
errGaëtan Gavazzi; Bertrand Fougère; Olivier Hanon; Isabel Leroux-Roels; Etienne Brochot; Elodie Blanchard; Colin A Russell; Marc Paccalin; Tino F Schwarz
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Efficacy, safety, and immunogenicity of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) in older adults over three respiratory syncytial virus seasons (AReSVi-006): a multicentre, randomised, observer-blinded, placebo-controlled, phase 3 trialAS01E佐剂呼吸道合胞病毒前融合F蛋白疫苗（RSVPreF3 OA）在老年人群中的有效性、安全性和免疫原性研究（跨越三个呼吸道合胞病毒流行季）（AReSVi-006）：一项多中心、随机、观察者设盲、安慰剂对照的III期临床试验
errThe Lancet Respiratory Medicine
IF0
err2025-04-14
err0
PREAI
errMichael G Ison; Alberto Papi; Eugene Athan; Robert G Feldman; Joanne M Langley; Dong-Gun Lee; Isabel Leroux-Roels; Federico Martinon-Torres; Tino F Schwarz; Richard N van Zyl-Smit; Susanna Cuadripani; Quentin Deraedt; Nancy Dezutter; Catherine Gerard; Laurence Fissette; Stebin Xavier; Marie-Pierre David; Aurélie Olivier; Marie Van der Wielen; Dominique Descamps; Manuel Zocco
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Evaluation of Safety, Immunogenicity and Cross-Reactive Immunity of OVX836, a Nucleoprotein-Based Universal Influenza Vaccine, in Older Adults
errVACCINES
IF3.4
err2024-12-11
err0
errOAAI
errJacobs, Bart; Leroux-Roels, Isabel; Bruhwyler, Jacques; Groth, Nicola; Waerlop, Gwenn; Janssens, Yorick; Tourneur, Jessika; De Boever, Fien; Alhatemi, Azhar; Moris, Philippe; Le Vert, Alexandre; Leroux-Roels, Geert; Nicolas, Florence
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Safety and immunogenicity of the live-attenuated hRVFV-4s vaccine against Rift Valley fever in healthy adults: a dose-escalation, placebo-controlled, first-in-human, phase 1 randomised clinical trial
errLANCET INFECTIOUS DISEASES
IF31
err2024-11-01
err1
PREAI
errLeroux-Roels, Isabel; Prajeeth, Chittappen Kandiyil; Aregay, Amare; Nair, Niranjana; Rimmelzwaan, Guus F.; Osterhaus, Albert D. M. E.; Kardinahl, Simone; Pelz, Sabrina; Bauer, Stephan; D'Onofrio, Valentino; Alhatemi, Azhar; Jacobs, Bart; De Boever, Fien; Porrez, Sharon; Waerlop, Gwenn; Punt, Carine; Hendriks, Bart; von Mauw, Ellemieke; van de Water, Sandra; Harders-Westerveen, Jose; Rockx, Barry; van Keulen, Lucien; Kortekaas, Jeroen; Leroux-Roels, Geert; Schreur, Paul J. Wichgers
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Safety and Immunogenicity of an Adjuvanted Clostridioides difficile Vaccine Candidate in Healthy Adults: A Randomized Placebo-Controlled Phase 1 Study
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-10-24
err0
errOAAI
errLeroux-Roels, Isabel; Alhatemi, Azhar; Caubet, Magalie; De Boever, Fien; de Wergifosse, Bertrand; El Idrissi, Mohamed; Ferreira, Guilherme S.; Jacobs, Bart; Lambert, Axel; Morel, Sandra; Servais, Charlotte; Yarzabal, Juan Pablo
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Safety and Immunogenicity of a Carbohydrate Fatty Acid Monosulphate Ester Adjuvant Combined with a Low-Dose Quadrivalent Split-Virion Inactivated Influenza Vaccine: A Randomised, Observer-Blind, Active-Controlled, First-in-Human, Phase 1 Study
errVACCINES
IF3.4
err2024-09-10
err1
errOAAI
errD'Onofrio, Valentino; Porrez, Sharon; Jacobs, Bart; Alhatemi, Azhar; De Boever, Fien; Waerlop, Gwenn; Michels, Els; Vanni, Francesca; Manenti, Alessandro; Leroux-Roels, Geert; Platenburg, Peter Paul; Hilgers, Luuk; Leroux-Roels, Isabel
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Microbiological evaluation of ultraviolet C light-emitting diodes for disinfection of medical instruments
errHELIYON
IF3.6
err2024-09-01
err0
errOAAI
errSiwe, Hannah; Aerssens, Annelies; Flour, Mieke V.; Ternest, Silke; Van Simaey, Leen; Verstraeten, Duncan; Kalmar, Alain F.; Leroux-Roels, Isabel; Meuleman, Philip; Cools, Piet
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Safety and Immunogenicity of a 4-Component Generalized Modules for Membrane Antigens Shigella Vaccine in Healthy European Adults: Randomized, Phase 1/2 Study
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-06-10
err2
errOAAI
errLeroux-Roels, Isabel; Maes, Cathy; Mancini, Francesca; Jacobs, Bart; Sarakinou, Eleanna; Alhatemi, Azhar; Joye, Jasper; Grappi, Silvia; Cilio, Giulia Luna; Serry-Bangura, Alimamy; Vitali, Claudia G.; Ferruzzi, Pietro; Marchetti, Elisa; Necchi, Francesca; Rappuoli, Rino; De Ryck, Iris; Auerbach, Jochen; Colucci, Anna M.; Rossi, Omar; Conti, Valentino; Scorza, Francesco Berlanda; Arora, Ashwani Kumar; Micoli, Francesca; Podda, Audino; Nakakana, Usman N.; Shigella Project Team, Giulia
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Environmental sustainability and antimicrobials: an underestimated problem with far-reaching consequences
errINTENSIVE CARE MEDICINE
IF21.2
err2024-01-29
err2
PREAI
errDe Waele, Jan J.; Leroux-Roels, Isabel; Conway-Morris, Andrew
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Efficacy and Safety of Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine (RSVPreF3 OA) in Older Adults Over 2 RSV Seasons呼吸道合胞病毒 (RSV) 融合F蛋白疫苗 (RSVPreF3 OA) 在2个RSV季节的老年人中的功效和安全性
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2024-01-22
err50
errOAAI
errIson, Michael G.; Papi, Alberto; Athan, Eugene; Feldman, Robert G.; Langley, Joanne M.; Lee, Dong-Gun; Leroux-Roels, Isabel; Martinon-Torres, Federico; Schwarz, Tino F.; van Zyl-Smit, Richard N.; Verheust, Celine; Dezutter, Nancy; Gruselle, Olivier; Fissette, Laurence; David, Marie-Pierre; Kostanyan, Lusine; Hulstrom, Veronica; Olivier, Aurelie; van der Wielen, Marie; Descamps, Dominique
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