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Shikhar Mehrotra

medical university of south carolina

44H指数
290论文数
5.7K被引数
收录论文 102
发表时间
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Sphingosine kinase-2 inhibition promotes immunogenic differentiation of myeloid-derived suppressor cells through an Acetyl-CoA carboxylase-phosphatidylcholine axis鞘氨醇激酶-2抑制通过乙酰辅酶A羧化酶-磷脂酰胆碱轴促进髓源性抑制细胞的免疫原性分化
errNature Communications
IF15.7
err2026-06-02
err0
errOAAI
errParamita Chakraborty; Shilpak Chatterjee; Mohamed Faisal Kassir; Wyatt Wofford; Seungho Choi; Natalia Oleinik; Ozge Saatci; Odai Darawshi; Satyajit Das; Nathaniel Oberhoeltzer; Anupam Gautam; Stephanie Mills; Reid DeMass; Zacharia Hedley; Yueying Liu; Rasesh Y. Parikh; Sandip Paul; Souvik Seal; Charles D. Smith; Michael B. Lilly; Vamsi K. Gangaraju; Yuri Peterson; Meenal Mehrotra; Elizabeth Hill; Ozgur Sahin; Norbert Leitinger; Paulo C. Rodriguez; Besim Ogretmen; Shikhar Mehrotra
err分享
err收藏
The Dual Faces of S1P: Orchestrating Immune Responses in Health and DiseaseS1P的双面性：调控健康与疾病中的免疫应答
errCells
IF5.2
err2026-04-17
err0
errOAAI
errStephanie A. Mills; David Barr; Shikhar Mehrotra; Paramita Chakraborty
err分享
err收藏
Phase II Trial of Opaganib Addition in Metastatic Castration-Resistant Prostate Cancer After Disease Progression on Abiraterone or EnzalutamideII期临床试验：在阿比特龙或恩扎卢amide治疗进展后的转移性去势抵抗性前列腺癌中添加奥帕吉布
errCancer Medicine
IF3.1
err2026-04-14
err0
errOAAI
errJacqueline T. Brown; Bassel Nazha; Anna C. Ferreira; Kent Armeson; Elizabeth G. Hill; Besim Ogretmen; Shikhar Mehrotra; Alan Brisendine; George Magrath; Terry F. Plasse; Theodore Stewart Gourdin; Omer Kucuk; Michael Lilly
err分享
err收藏
PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer developmentPCBP1与单链多聚胞嘧啶基序的结合增强了cGAS传感并抑制了乳腺癌发展
errCommunications Biology
IF5.1
err2026-01-07
err0
errOAAI
errCécile Fréreux; Joseph A. Q. Karam; Breege V. Howley; Bryan Granger; Paramita Chakraborty; Silvia Vaena; Martin Romeo; Annamarie C. Dalton; Bidyut K. Mohanty; Shikhar Mehrotra; Philip H. Howe
err分享
err收藏
Secreted frizzled-related protein 2 monoclonal antibody-mediated IFN-ϒ reprograms tumor-associated macrophages to suppress triple negative breast cancer分泌性卷曲相关蛋白2单克隆抗体介导的IFN-ϒ重编程肿瘤相关巨噬细胞以抑制三阴性乳腺癌
errBreast Cancer Research
IF5.6
err2025-12-05
err0
errOAAI
errLillian Hsu; Julie Siegel; Patrick Nasarre; Nathaniel Oberholtzer; Rupak Mukherjee; Eleanor Hilliard; Paramita Chakraborty; Rachel A. Burge; Elizabeth C. O’Quinn; Olivia Sweatt; Mohamed Faisal Kassir; G. Aaron Hobbs; Michael Ostrowski; Ann-Marie Broome; Shikhar Mehrotra; Nancy Klauber-DeMore
err分享
err收藏
S1P transporter SPNS2 expression modulates T cell immune response
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errChoi, Seungho; Chakraborty, Paramita; Hedley, Zachariah; Lee, Han; Ogretmen, Besim; Mehrotra, Shikhar
err分享
err收藏
Phosphatidylcholine regulation via sphingosine kinase 2 inhibition drives immunogenic reprogramming of myeloid-derived suppressor cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errChakraborty, Paramita; Chatterjee, Shilpak; Faisal, Mohamed; Wofford, Wyatt; Oberholtzer, Nathaniel; Choi, Seungho; Das, Satyajit; Liu, Yueying; Hedley, Zachariah; Demass, Reid; Hill, Elizabeth; Lilly, Michael; Peterson, Yuri K.; Ogretmen, Besim; Mehrotra, Shikhar
err分享
err收藏
Optimizing expansion of metabolically enhanced tumor infiltrating lymphocytes for multiple cancers
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errMills, Stephanie Ann; Chakraborty, Paramita; Liu, Yueying; Zavestoski, Jadan; Das, Satyajit; Liu, Jian; Klinzing, Kathleen; Orr, Brian; Gibney, Barry; Yoon, Angela; Newman, Jason; Roggin, Kevin; Hawkins, William; Lilly, Michael; Mehrotra, Shikhar
err分享
err收藏
Harnessing Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Opportunities and Barriers to Clinical Integration利用肿瘤浸润淋巴细胞治疗三阴性乳腺癌：临床整合的机遇与障碍
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-05-01
err0
errOAAI
errColeman, Cara; Selvakumar, Tharakeswari; Thurlapati, Aswani; Graf, Kevin; Pavuluri, Sushma; Mehrotra, Shikhar; Sahin, Ozgur; Sivapiragasam, Abirami
err分享
err收藏
Osteogenesis imperfecta: exploring an autoimmune and immunotherapy perspective成骨不全症：从自身免疫与免疫治疗角度的探索
errJBMR PLUS
IF2.4
err2025-04-09
err0
errOAAI
errGoddard, Jackson F.; Mehrotra, Shikhar; Mehrotra, Meenal
err分享
err收藏
CD38-mediated metabolic reprogramming promotes the stability and suppressive function of regulatory T cells in tumorCD38介导的代谢重编程促进肿瘤中调节性T细胞的稳定性及其抑制功能。
errSCIENCE ADVANCES
IF12.5
err2025-03-21
err0
errOAAI
errSarkar, Ishita; Basak, Debashree; Ghosh, Puspendu; Gautam, Anupam; Bhoumik, Arpita; Singh, Praveen; Kar, Anwesha; Mahanti, Shaun; Chowdhury, Snehanshu; Chakraborty, Lagnajita; Mondal, Soumya; Mukherjee, Ramanuj; Mehrotra, Shikhar; Majumder, Saikat; Sengupta, Shantanu; Paul, Sandip; Chatterjee, Shilpak
err分享
err收藏
Pilot clinical trial of neoadjuvant toll-like receptor 7 agonist (Imiquimod) immunotherapy in early-stage oral squamous cell carcinoma
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-01-27
err0
errOAAI
errYoon, Angela J.; Carvajal, Richard D.; Graboyes, Evan M.; Kaczmar, John M.; Albergotti, William G.; Kejner, Alexandra E.; Troob, Scott H.; Philipone, Elizabeth; Anoma, Jean-Sebastien; Armeson, Kent E.; Hill, Elizabeth G.; Richardson, Mary S.; Woods, Tina R.; Chera, Bhishamjit S.; Nourollah-Zadeh, Farzad; Lee, Byung J.; Pandruvada, Subramanya; Kourtidis, Antonis; Kingsley, Christina; O'Quinn, Elizabeth C.; Mills, Stephanie; Jordan, Victoria C.; Spencer, Mike; Fails, Danielle; Mckee, Trevor D.; Zaidi, Mark; Brisendine, Alan; Horn, Shane; Mehrotra, Shikhar; Ogretmen, Besim; Newman, Jason G.
err分享
err收藏
H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response
errSCIENCE ADVANCES
IF12.5
err2024-11-15
err0
errOAAI
errOberholtzer, Nathaniel; Chakraborty, Paramita; Kassir, Mohamed Faisal; Dressman, James; Das, Satyajit; Mills, Stephanie; Comte-Walters, Susana; Gooz, Monika; Choi, Seungho; Parikh, Rasesh Y.; Hedley, Zacharia; Vaena, Silvia; Demass, Reid; Scurti, Gina; Romeo, Martin; Gangaraju, Vamsi K.; Berto, Stefano; Hill, Elizabeth; Ball, Lauren E.; Mehta, Anand S.; Maldonado, Eduardo N.; Nishimura, Michael I.; Ogretmen, Besim; Mehrotra, Shikhar
err分享
err收藏
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
errCELL REPORTS
IF6.9
err2024-08-01
err0
errOAAI
errWofford, Wyatt; Kim, Jisun; Kim, Dosung; Janneh, Alhaji H.; Lee, Han Gyul; Atilgan, Cansu; Oleinik, Natalia; Kassir, Mohamed Faisal; Saatci, Ozge; Chakraborty, Paramita; Tokat, Unal Metin; Gencer, Salih; Howley, Breege; Howe, Philip; Mehrotra, Shikhar; Sahin, Ozgur; Ogretmen, Besim
err分享
err收藏
Restoring NAD plus levels sensitize checkpoint resistant tumors to PD-1 therapy mediated through macrophage-NK-T cell crosstalk
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errChakraborty, Paramita; Chatterjee, Shilpak; Subramanian, Suganya; Parikh, Rasesh; Hedley, Zacharia; Vaena, Silvia; Romeo, Martin; Schooten, Wim; Gangaraju, Vamsi; Berto, Stefano; Mehrotra, Shikhar
err分享
err收藏
Reactivation of mitotic arrest upon targeting TACC3 restores immunogenic cell death and T-DM1 response in HER2-positive breast cancer
errCANCER RESEARCH
IF16.6
err2024-04-05
err1
PREAI
errSaatci, Ozge; Gedik, Mustafa Emre; Oberholtzer, Nathaniel; Uner, Meral; Akbulut, Ozge; Cetin, Metin; Aras, Mertkaya; Ibis, Kubra; Caliskan, Burcu; Banoglu, Erden; Wiemann, Stefan; Uner, Aysegul; Aksoy, Sercan; Mehrotra, Shikhar; Sahin, Ozgur
err分享
err收藏
Golgihi T cells exhibit reduced susceptibility to exhaustion and improved tumor control
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errOberholtzer, Nathaniel; Chakraborty, Paramita; Kassir, Mohamed Faisal; Dressman, James; Hedley, Zacharia; Scurti, Gina; Gooz, Monika; Ball, Lauren E.; Hill, Elizabeth; Mehta, Anand S.; Maldonado, Eduardo N.; Nishimura, Michael I.; Ogretmen, Besim; Mehrotra, Shikhar
err分享
err收藏
Alzheimer's disease-associated amyloid precursor protein improves anti-tumor immunity by inhibiting ceramide-mediated lethal mitophagy and restoring mitochondrial fumarate metabolism in aging T-cells
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errKassir, Mohamed Faisal; Lee, Han G.; Oleinik, Natalia; Wofford, Wyatt; Walton, Chase; Atilgan, F. Cansu; Chakraborty, Paramita; Calisir, Kubra; Sahin, Ozgur; Mehrotra, Shikhar; Ogretmen, Besim
err分享
err收藏
Lipid metabolism alterations promote TNBC metastasis and immunotherapy resistance via PD-L1 internalization and signaling
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errWofford, Wyatt O.; Kim, Jisun; Kim, Dosung; Janneh, Alhaji H.; Lee, Han Gyul; Atilgan, F. Cansu; Oleinik, Natalia; Hill, Elizabeth; Saatci, Ozge; Gencer, Salih; Chakraborty, Paramita; Mehrotra, Shikhar; Sahin, Ozgur; Ogretmen, Besim
err分享
err收藏
CD38-RyR2 axis-mediated signaling impedes CD8+ T cell response to anti-PD1 therapy in cancerCD38-RyR2轴介导的信号传导阻碍CD8 T细胞对癌症anti-PD1治疗的反应
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-07
err2
errOAAI
errKara, Anwesha; Ghosha, Puspendu; Gautamc, Anupam; Chowdhurya, Snehanshu; Basaka, Debashree; Sarkara, Ishita; Bhoumika, Arpita; Barmanb, Shubhrajit; Chakrabortyf, Paramita; Mukhopadhyayg, Asima; Mehrotraf, Shikhar; Ganesane, Senthil Kumar; Paulh, Sandip; Chatterjeea, Shilpak
err分享
err收藏

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