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Sparsentan reduces glomerular dysfunction and proteinuria in a rat model of serum-factor-induced nephrotic syndrome Sparsentan可减轻血清因子诱导的肾病综合征大鼠模型中的肾小球功能障碍和蛋白尿。 Crompton, Michael; Stowell-Connolly, Holly; Mills, Jack; Vasylchenko, Viktoriia; Jenkinson, Celia P.; Hendry, Bruce; Komers, Radko; Kawachi, Hiroshi; Butler, Matthew; Welsh, Gavin; Foster, Rebecca; Satchell, Simon 分享 收藏
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A small molecule chaperone rescues keratin-8 mediated trafficking of misfolded podocin to correct genetic Nephrotic Syndrome 小分子伴侣可挽救角蛋白8介导的错误折叠的podocin运输，以纠正遗传性肾病综合征 Kuzmuk, Valeryia; Pranke, Iwona; Rollason, Ruth; Butler, Matthew; Ding, Wen Y.; Beesley, Matthew; Waters, Aoife M.; Coward, Richard J.; Sessions, Richard; Tuffin, Jack; Foster, Rebecca R.; Mollet, Geraldine; Antignac, Corinne; Edelman, Aleksander; Welsh, Gavin I.; Saleem, Moin A. 分享 收藏
National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS) study 全国统一肾脏转化研究企业: 特发性肾病综合征 (NURTuRE-INS) 研究 Colby, Elizabeth; Hayward, Samantha; Benavente, Melissa; Robertson, Fiona; Bierzynska, Agnieszka; Osborne, Amy; Parmesar, Kevon; Afzal, Maryam; Chapman, Tracey; Ullah, Fatima; Davies, Elaine; Nation, Michael; Cook, Wendy; Johnson, Tim; Andag, Uwe; Radresa, Olivier; Skroblin, Philipp; Bayerlova, Michaela; Unwin, Robert; Vuilleumier, Nicolas; Banks, Rosamonde E.; Braddon, Fiona; Koziell, Ania; Taal, Maarten W.; Welsh, Gavin, I; Saleem, Moin A. 分享 收藏
Adiponectin Reduces Glomerular Endothelial Glycocalyx Disruption and Restores Glomerular Barrier Function in a Mouse Model of Type 2 Diabetes Fawaz, Sarah; Alonso, Aldara Martin; Qiu, Yan; Ramnath, Raina; Stowell-Connolly, Holly; Gamez, Monica; May, Carl; Down, Colin; Coward, Richard J.; Butler, Matthew J.; Welsh, Gavin I.; Satchell, Simon C.; Foster, Rebecca R. 分享 收藏
Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease 多变量典型相关分析确定了慢性肾病的其他遗传变异 Osborne, Amy J.; Bierzynska, Agnieszka; Colby, Elizabeth; Andag, Uwe; Kalra, Philip A.; Radresa, Olivier; Skroblin, Philipp; Taal, Maarten W.; Welsh, Gavin I.; Saleem, Moin A.; Campbell, Colin 分享 收藏
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes (vol 23, 50, 2024) Gamez, Monica; Elhegni, Hesham E.; Fawaz, Sarah; Ho, Kwan Ho; Campbell, Neill W.; Copland, David A.; Onions, Karen L.; Butler, Matthew J.; Wasson, Elizabeth J.; Crompton, Michael; Ramnath, Raina D.; Qiu, Yan; Yamaguchi, Yu; Arkill, Kenton P.; Bates, David O.; Turnbull, Jeremy E.; Zubkova, Olga V.; Welsh, Gavin I.; Atan, Denize; Satchell, Simon C.; Foster, Rebecca R. 分享 收藏
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes Gamez, Monica; Elhegni, Hesham E.; Fawaz, Sarah; Ho, Kwan Ho; Campbell, Neill W.; Copland, David A.; Onions, Karen L.; Butler, Matthew J.; Wasson, Elizabeth J.; Crompton, Michael; Ramnath, Raina D.; Qiu, Yan; Yamaguchi, Yu; Arkill, Kenton P.; Bates, David O.; Turnbull, Jeremy E.; Zubkova, Olga V.; Welsh, Gavin I.; Atan, Denize; Satchell, Simon C.; Foster, Rebecca R. 分享 收藏
Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation 志贺毒素通过内皮补体激活靶向足细胞引起溶血性尿毒症综合征 Bowen, Emily E.; Hurcombe, Jennifer A.; Barrington, Fern; Keir, Lindsay S.; Farmer, Louise K.; Wherlock, Matthew D.; Ortiz-Sandoval, Carolina G.; Brun, Valentina; Bohorquez-Hernandez, Arlette; Diatlov, Daniel; Rostam-Shirazi, Niyousha; Wells, Sara; Stewart, Michelle; Teboul, Lydia; Lay, Abigail C.; Butler, Matthew J.; Pope, Robert J. P.; Larkai, Eva M. S.; Morgan, B. Paul; Moppett, John; Satchell, Simon C.; Welsh, Gavin I.; Walker, Patrick D.; Licht, Christoph; Saleem, Moin; Coward, Richard J. M. 分享 收藏
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Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome 腺相关病毒基因治疗可预防肾病综合征遗传模型中肾脏疾病的进展 Ding, Wen Y.; Kuzmuk, Valeryia; Hunter, Sarah; Lay, Abigail; Hayes, Bryony; Beesley, Matthew; Rollason, Ruth; Hurcombe, Jennifer A.; Barrington, Fern; Masson, Catrin; Cathery, William; May, Carl; Tuffin, Jack; Roberts, Timothy; Mollet, Geraldine; Chu, Colin J.; McIntosh, Jenny; Coward, Richard J.; Antignac, Corinne; Nathwani, Amit; Welsh, Gavin I.; Saleem, Moin A. 分享 收藏
Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events 小鼠足细胞蛋白酶激活受体1刺激产生反映人类疾病信号事件的局灶性节段性肾小球硬化 May, Carl J.; Chesor, Musleeha; Hunter, Sarah E.; Hayes, Bryony; Barr, Rachel; Roberts, Tim; Barrington, Fern A.; Farmer, Louise; Ni, Lan; Jackson, Maisie; Snethen, Heidi; Tavakolidakhrabadi, Nadia; Goldstone, Max; Gilbert, Rodney; Beesley, Matt; Lennon, Rachel; Foster, Rebecca; Coward, Richard; Welsh, Gavin I.; Saleem, Moin A. 分享 收藏
Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx Crompton, Michael; Ferguson, Joanne K.; Ramnath, Raina D.; Onions, Karen L.; Ogier, Anna S.; Gamez, Monica; Down, Colin J.; Skinner, Laura; Wong, Kitty H.; Dixon, Lauren K.; Sutak, Judit; Harper, Steven J.; Pontrelli, Paola; Gesualdo, Loreto; Heerspink, Hiddo L.; Toto, Robert D.; Welsh, Gavin I.; Foster, Rebecca R.; Satchell, Simon C.; Butler, Matthew J. 分享 收藏
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