David Rueda - Publications, H-index & Citations

David Rueda

imperial college london

43H指数

180论文数

5.0K被引数

收录论文 75

发表时间

HSV-1 origin binding protein UL9 forms intermolecular DNA tethers and intramolecular DNA loops HSV-1起始结合蛋白UL9形成分子间DNA锚定物和分子内DNA环

Nature Communications

IF15.7

2026-06-29

OAAI

Anita F. Meier; Jan Vuckovic; Paul Girvan; Adam S. B. Jalal; Erin Cutts; Theodora Brophy; Benjamin Ambrose; David S. Rueda

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity 超卷诱导的CRISPR-Cas9脱靶活动的结构基础

Nature

IF48.5

2026-03-25

OAAI

Quentin M. Smith; Sylvia Whittle; Ricardo J. Aramayo; Daniel E. Rollins; Adam S. B. Jalal; Deborah I. Egharevba; Kyle L. Morris; Alice L. B. Pyne; David S. Rueda

Stabilization of the hexasome intermediate during histone exchange by yeast SWR1 complex

MOLECULAR CELL

IF16.6

2024-10-01

OAAI

Jalal, Adam S. B.; Girvan, Paul; Chua, Eugene Y. D.; Liu, Lexin; Wang, Shijie; McCormack, Elizabeth A.; Skehan, Michael T.; Knight, Carol L.; Rueda, David S.; Wigley, Dale B.

Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA

NUCLEIC ACIDS RESEARCH

IF13.1

2024-09-12

OAAI

Akita, Masaki; Girvan, Paul; Spirek, Mario; Novacek, Jiri; Rueda, David; Prokop, Zbynek; Krejci, Lumir

Negative DNA supercoiling induces genome-wide Cas9 off-target activity 负DNA超卷诱导全基因组Cas9脱靶活性

MOLECULAR CELL

IF16.6

2023-10-01

OAAI

Newton, Matthew D.; Losito, Marialucrezia; Smith, Quentin M.; Parnandi, Nishita; Taylor, Benjamin J.; Akcakaya, Pinar; Maresca, Marcello; van Eijk, Patrick; Reed, Simon H.; Boulton, Simon J.; King, Graeme A.; Cuomo, Maria Emanuela; Rueda, David S.

DNA-directed termination of RNA polymerase II transcription

MOLECULAR CELL

IF16.6

2023-09-01

OAAI

Han, Zhong; Moore, George A.; Mitter, Richard; Martinez, David Lopez; Wan, Li; Svejstrup, A. Barbara Dirac; Rueda, David S.; Svejstrup, Jesper Q.

Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein 全长人BRCA2蛋白直接和扩散辅助RAD51成核的可视化

MOLECULAR CELL

IF16.6

2023-08-01

OAAI

Belan, Ondrej; Greenhough, Luke; Kuhlen, Lucas; Anand, Roopesh; Kaczmarczyk, Artur; Gruszka, Dominika T.; Yardimci, Hasan; Zhang, Xiaodong; Rueda, David S.; West, Stephen C.; Boulton, Simon J.

The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle

PLOS PATHOGENS

IF4.9

2023-07-31

OAAI

Aristodemou, Aris E. N. R.; Rueda, David; Taylor, Graham R.; Bangham, Charles R. M.

3D modelling of cavity-free lasing in nitrogen plasma filaments

OPTICS EXPRESS

IF3.3

2023-02-22

OAAI

Lopez, Santiago; Garcia, Alicia; Rueda, David; Oliva, Eduardo

POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells POLQ密封复制后ssDNA缺口以维持BRCA缺陷癌细胞的基因组稳定性

MOLECULAR CELL

IF16.6

2022-12-01

OAAI

Belan, Ondrej; Sebald, Marie; Adamowicz, Marek; Anand, Roopesh; Vancevska, Aleksandra; Neves, Joana; Grinkevich, Vera; Hewitt, Graeme; Segura-Bayona, Sandra; Bellelli, Roberto; Robinson, Helen M. R.; Higgins, Geoff S.; Smith, Graeme C. M.; West, Stephen C.; Rueda, David S.; Boulton, Simon J.

Search and processing of Holliday junctions within long DNA by junction-resolving enzymes 通过连接分解酶搜索和处理长DNA中的霍利迪连接

NATURE COMMUNICATIONS

IF15.7

2022-10-07

OAAI

Kaczmarczyk, Artur P.; Declais, Anne-Cecile; Newton, Matthew D.; Boulton, Simon J.; Lilley, David M. J.; Rueda, David S.

A Minimal Load-and-Lock RuII Luminescent DNA Probe

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2021-08-11

OAAI

Newton, Matthew D.; Fairbanks, Simon D.; Thomas, Jim A.; Rueda, David S.

Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins

MOLECULAR CELL

IF16.6

2021-03-01

OAAI

Belan, Ondrej; Barroso, Consuelo; Kaczmarczyk, Artur; Anand, Roopesh; Federico, Stefania; O'Reilly, Nicola; Newton, Matthew D.; Maeots, Erik; Enchev, Radoslav I.; Martinez-Perez, Enrique; Rueda, David S.; Boulton, Simon J.

Live cell imaging of single RNA molecules with fluorogenic Mango II arrays

NATURE COMMUNICATIONS

IF15.7

2020-03-09

118

OAAI

Cawte, Adam D.; Unrau, Peter J.; Rueda, David S.

Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling

PLOS PATHOGENS

IF4.9

2019-11-18

OAAI

Miura, Michi; Dey, Supravat; Ramanayake, Saumya; Singh, Abhyudai; Rueda, David S.; Bangham, Charles R. M.

A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules 束缚DNA分子中粘附素的保守ATP和Scc2/4依赖性活性

SCIENCE ADVANCES

IF12.5

2019-11-01

OAAI

Gutierrez-Escribano, Pilar; Newton, Matthew D.; Llauro, Aida; Huber, Jonas; Tanasie, Loredana; Davy, Joseph; Aly, Isabel; Aramayo, Ricardo; Montoya, Alex; Kramer, Holger; Stigler, Johannes; Rueda, David S.; Aragon, Luis

Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer

NATURE COMMUNICATIONS

IF15.7

2019-09-13

OAAI

Wilson, Marcus D.; Renault, Ludovic; Maskell, Daniel P.; Ghoneim, Mohamed; Pye, Valerie E.; Nans, Andrea; Rueda, David S.; Cherepanov, Peter; Costa, Alessandro

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system

NATURE IMMUNOLOGY

IF27.6

2019-08-26

OAAI

Bruno, Ludovica; Ramlall, Vijendra; Studer, Romain A.; Sauer, Stephan; Bradley, David; Dharmalingam, Gopuraja; Carroll, Thomas; Ghoneim, Mohamed; Chopin, Michael; Nutt, Stephen L.; Elderkin, Sarah; Rueda, David S.; Fisher, Amanda G.; Siggers, Trevor; Beltrao, Pedro; Merkenschlager, Matthias

DNA stretching induces Cas9 off-target activity

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2019-02-25

OAAI

Newton, Matthew D.; Taylor, Benjamin J.; Driessen, Rosalie P. C.; Roos, Leonie; Cvetesic, Nevena; Allyjaun, Shenaz; Lenhard, Boris; Cuomo, Maria Emanuela; Rueda, David S.

Optimal molecular crowding accelerates group II intron folding and maximizes catalysis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-11-05

OAAI

Paudel, Bishnu P.; Fiorini, Erica; Borner, Richard; Sigel, Roland K. O.; Rueda, David S.

研究方向