Conggang Zhang

tsinghua-peking center for life sciences

H指数:19

被引数:3,115

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Expression characteristics of the cGAS–STING pathway in individuals coinfected with HIV and Mycobacterium tuberculosis

HIV和结核分枝杆菌双重感染者中cGAS–STING通路表达特征

BMC Microbiology

IF4.2

2026-09-230

OAAI

VEGFR2 inhibition potentiates STING-mediated antitumor immunity

VEGFR2抑制增强了STING介导的抗肿瘤免疫

Cell Reports

IF6.9

2026-06-180

OAAI

NF-κB activation enhances STING signaling by altering microtubule-mediated STING trafficking

NF-κB的激活通过改变微管介导的STING转运来增强STING信号通路。

Cell Reports

IF6.9

2025-12-180

OAAI

Activation of stimulator of interferon genes (STING) and inhibition of vascular endothelial growth factor receptor (VEGFR) by telatinib induce antitumor activity

通过telatinib激活干扰素基因刺激因子(STING)并抑制血管内皮生长因子受体(VEGFR)，可诱导抗肿瘤活性。

Journal of Biological Chemistry

IF3.9

2025-12-090

OAAI

LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity

LL-37将免疫反应性cGAMP转运以激活STING信号通路并增强干扰素介导的宿主抗病毒免疫。

Cell Reports

IF6.9

2025-12-060

OAAI

A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement

一种化学激动剂和内质网驻留脂质PI4P通过诱导跨膜螺旋重排来激活STING

Immunity

IF26.3

2025-12-050

PRE

Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy

沉默PCSK9重塑STING的时空激活，用于安全有效的癌症免疫治疗

Nature Communications

IF15.7

2025-11-250

OAAI

Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation

病毒感染引起的膜完整性变化会激活sphingomyelinase SMPDL3B，通过降解cGAMP来抑制cGAS-STING信号通路。

Immunity

IF26.3

2025-11-210

OAAI

Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation

病毒感染引起的膜完整性变化会激活SMPDL3B型鞘氨醇磷酸酶，通过降解cGAMP来抑制cGAS-STING信号通路。

Immunity

IF26.3

2025-10-310

OAAI

Regulation of cGAS-STING signalling and its diversity of cellular outcomes

cGAS-STING信号的调节及其细胞结果的多样性

NATURE REVIEWS IMMUNOLOGY

IF60.9

2025-01-078

PRE

The cGAS-STING pathway in HIV-1 and Mycobacterium tuberculosis coinfection

INFECTION

IF3.6

2024-11-070

PRE

BL-918 activates PINK1/Parkin signaling pathway to ameliorate the progression of Parkinson's disease

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-08-010

OAAI

Herpes simplex virus 1 accelerates the progression of Alzheimer's disease by modulating microglial phagocytosis and activating NLRP3 pathway

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-07-181

OAAI

Microtubule disruption synergizes with STING signaling to show potent and broad-spectrum antiviral activity

PLOS PATHOGENS

IF4.9

2024-02-263

OAAI

SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing

SMPDL3A是由LXR介导的脂质代谢诱导的cGAMP降解酶，以限制cgas-sting DNA传感

IMMUNITY

IF26.3

2023-11-0124

PRE

A universe of second messengers for cGLR-STING signaling

IMMUNITY

IF26.3

2023-09-011

OAAI

Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity

NATURE COMMUNICATIONS

IF15.7

2023-06-3044

OAAI

NF-KB activation enhances STING signaling by altering microtubule-mediated STING trafficking

Nf-kb激活通过改变微管介导的STING运输来增强STING信号传导

CELL REPORTS

IF6.9

2023-03-0181

ORP9 and ORP10 form a heterocomplex to transfer phosphatidylinositol 4-phosphate at ER-TGN contact sites

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-02-286

USP15 promotes cGAS activation through deubiquitylation and liquid condensation

NUCLEIC ACIDS RESEARCH

IF13.1

2022-10-168

OAAI

Conggang Zhang

个人简介

教育背景

工作经历

荣誉奖项

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