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J

Jorge Moscat

Weill Cornell Medicine

85H指数
279论文数
2.4W被引数
收录论文 114
发表时间
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Targeting fibroblast derived thrombospondin 2 disrupts an immune-exclusionary environment at the tumor front in colorectal cancer靶向成纤维细胞衍生的血栓调节蛋白2破坏了结直肠癌肿瘤前沿的免疫排斥性环境
errNature Communications
IF15.7
err2025-11-23
err0
errOAAI
errKosuke Iwane; Yuki Nakanishi; Yu Muta; Jiayu Chen; Kento Yasumura; Mayuki Omatsu; Naoki Aoyama; Munehiro Ikeda; Yoko Masui; Liyang Cai; Go Yamakawa; Kensuke Hamada; Kenta Mizukoshi; Munenori Kawai; Kei Iimori; Shinnosuke Nakayama; Nobukazu Agatsuma; Takahiro Utsumi; Munemasa Nagao; Takahisa Maruno; Yukiko Hiramatsu; Nobuyuki Kakiuchi; Masahiro M. Nakagawa; Yasuhiro Fukui; Yukina Kusunoki; Hiroaki Kasashima; Masakazu Fujimoto; Yoshiro Itatani; Toshiaki Kogame; Akihisa Fukuda; Masakazu Yashiro; Kiyoshi Maeda; Kenji Kabashima; Kazutaka Obama; Seishi Ogawa; Maria T. Diaz-Meco; Jorge Moscat; Hiroshi Seno
err分享
err收藏
Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer自扩增NRF2-EZH2表观遗传环将KRAS启动的祖细胞转化为侵袭性胰腺癌
errNature Cancer
IF28.5
err2025-06-30
err0
PREAI
errLaura Antonucci; Na Li; Angeles Duran; Isidoro Cobo; Chiara Nicoletti; Kosuke Watari; Shuvro Prokash Nandi; Feng Zhu; Yongmei Zhao; Irene Riahi; Motoyuki Tsuda; Vidhi M. Shah; Terry Morgan; Trent Waugh; Luca Caputo; Yuan Liu; Alexandra Rundberg Nilsson; Hongxu Xian; Jelena Todoric; Li Gu; Elsa Sanchez-Lopez; Guido Eibl; Emily A. Vucic; Michal Krawczyk; Qianlan Xu; Andrew M. Lowy; Georgia Hatzivassiliou; Merone Roose-Girma; Dorota Skowronska-Krawczyk; David A. Scott; Dafna Bar-Sagi; Pablo Tamayo; Ying Wu; Rosalie C. Sears; Christopher K. Glass; Ludmil B. Alexandrov; Pier Lorenzo Puri; David W. Dawson; Yinling Hu; Maria T. Diaz-Meco; Jorge Moscat; Michael Karin
err分享
err收藏
Hijacking the powerhouse: Mitochondrial transfer and mitophagy as emerging mechanisms of immune evasion劫持能量工厂：线粒体转移和线粒体自噬作为新兴的免疫逃逸机制
errMOLECULAR CELL
IF16.6
err2025-04-01
err0
PREAI
errDiaz-Meco, Maria T.; Linares, Juan F.; Moscat, Jorge
err分享
err收藏
Opposing regulation of the STING pathway in hepatic stellate cells by NBR1 and p62 determines the progression of hepatocellular carcinoma
errMOLECULAR CELL
IF16.6
err2024-12-01
err0
PREAI
errNishimura, Sadaaki; Linares, F. Juan; L'Hermitte, Antoine; Duran, Angeles; Cid-Diaz, Tania; Martinez-Ordonez, Anxo; Ruiz-Martinez, Marc; Kudo, Yotaro; Marzio, Antonio; Heikenwalder, Mathias; Roberts, Lewis R.; Diaz-Meco, Maria T.; Moscat, Jorge
err分享
err收藏
Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation
errDEVELOPMENTAL CELL
IF8.7
err2024-08-01
err2
PREAI
errKinoshita, Hiroto; Martinez-Ordonez, Anxo; Cid-Diaz, Tania; Han, Qixiu; Duran, Angeles; Muta, Yu; Zhang, Xiao; Linares, Juan F.; Nakanishi, Yuki; Kasashima, Hiroaki; Yashiro, Masakazu; Maeda, Kiyoshi; Albaladejo-Gonzalez, Ana; Torres-Moreno, Daniel; Garcia-Solano, Jose; Conesa-Zamora, Pablo; Inghirami, Giorgio; Diaz-Meco, Maria T.; Moscat, Jorge
err分享
err收藏
Decoding colon cancer recurrence: Unveiling accurate predictions with attention-guided deep neural networks on histopathological whole slide images
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errAlexanderani, Mohammad K.; Omar, Mohamed; Greenblatt, Matthew; Cesarman, Ethel; Diaz-Meco, Maria T.; Moscat, Jorge; Marchionni, Luigi
err分享
err收藏
Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis
errNATURE COMMUNICATIONS
IF15.7
err2023-12-13
err5
errOAAI
errMuta, Yu; Linares, Juan F.; Martinez-Ordonez, Anxo; Duran, Angeles; Cid-Diaz, Tania; Kinoshita, Hiroto; Zhang, Xiao; Han, Qixiu; Nakanishi, Yuki; Nakanishi, Naoko; Cordes, Thekla; Arora, Gurpreet K.; Ruiz-Martinez, Marc; Reina-Campos, Miguel; Kasashima, Hiroaki; Yashiro, Masakazu; Maeda, Kiyoshi; Albaladejo-Gonzalez, Ana; Torres-Moreno, Daniel; Garcia-Solano, Jose; Conesa-Zamora, Pablo; Inghirami, Giorgio; Metallo, Christian M.; Osborne, Timothy F.; Diaz-Meco, Maria T.; Moscat, Jorge
err分享
err收藏
THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancerTHBS1-producing肿瘤浸润单核细胞样细胞在结直肠癌免疫抑制和转移中的作用
errNATURE COMMUNICATIONS
IF15.7
err2023-09-25
err21
errOAAI
errOmatsu, Mayuki; Nakanishi, Yuki; Iwane, Kosuke; Aoyama, Naoki; Duran, Angeles; Muta, Yu; Martinez-Ordonez, Anxo; Han, Qixiu; Agatsuma, Nobukazu; Mizukoshi, Kenta; Kawai, Munenori; Yamakawa, Go; Namikawa, Mio; Hamada, Kensuke; Fukunaga, Yuichi; Utsumi, Takahiro; Sono, Makoto; Masuda, Tomonori; Hata, Akitaka; Araki, Osamu; Nagao, Munemasa; Yoshikawa, Takaaki; Ogawa, Satoshi; Hiramatsu, Yukiko; Tsuda, Motoyuki; Maruno, Takahisa; Kogame, Toshiaki; Kasashima, Hiroaki; Kakiuchi, Nobuyuki; Nakagawa, Masahiro M.; Kawada, Kenji; Yashiro, Masakazu; Maeda, Kiyoshi; Saito, Yasuyuki; Matozaki, Takashi; Fukuda, Akihisa; Kabashima, Kenji; Obama, Kazutaka; Ogawa, Seishi; Sheibani, Nader; Diaz-Meco, Maria T.; Moscat, Jorge; Seno, Hiroshi
err分享
err收藏
Sessile serrated lesions with dysplasia: is it possible to nip them in the bud?
errJOURNAL OF GASTROENTEROLOGY
IF5.5
err2023-05-23
err11
errOAAI
errUtsumi, Takahiro; Yamada, Yosuke; Diaz-Meco, Maria Teresa; Moscat, Jorge; Nakanishi, Yuki
err分享
err收藏
Positioning atypical protein kinase C isoforms in the UV-induced apoptotic signaling cascade
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err166
errOAAI
errBerra, E; Municio, MM; Sanz, L; Frutos, S; DiazMeco, MT; Moscat, J
err分享
err收藏
Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err285
errOAAI
errCai, H; Smola, U; Wixler, V; EisenmannTappe, I; DiazMeco, MT; Moscat, J; Rapp, U; Cooper, GM
err分享
err收藏
Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err242
errOAAI
errSanchez, P; De Carcer, G; Sandoval, IV; Moscat, J; Diaz-Meco, MT
err分享
err收藏
MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err77
errOAAI
errDiaz-Meco, MT; Moscat, J
err分享
err收藏
The Drosophila atypical protein kinase C-Ref(2)P complex constitutes a conserved module for signaling in the toll pathway
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err61
errOAAI
errAvila, A; Silverman, N; Diaz-Meco, MT; Moscat, J
err分享
err收藏
Protein Kinase Cζ Represses the Interleukin-6 Promoter and Impairs Tumorigenesis In Vivo蛋白激酶c ζ 抑制Interleukin-6启动子并损害体内肿瘤发生
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err87
errOAAI
errGalvez, Anita S.; Duran, Angeles; Linares, Juan F.; Pathrose, Peterson; Castilla, Elias A.; Abu-Baker, Shadi; Leitges, Michael; Diaz-Meco, Maria T.; Moscat, Jorge
err分享
err收藏
Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err71
errOAAI
errLinares, Juan F.; Amanchy, Ramars; Diaz-Meco, Maria T.; Moscat, Jorge
err分享
err收藏
Phosphorylation of p62 by cdk1 Controls the Timely Transit of Cells through Mitosis and Tumor Cell Proliferation (vol 31, pg 105, 2011)
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-17
err1
errOAAI
errLinares, Juan F.; Amanchy, Ramars; Greis, Kenneth; Diaz-Meco, Maria T.; Moscat, Jorge
err分享
err收藏
Protein kinase Cλ/ι in cancer: a contextual balance of time and signals
errTRENDS IN CELL BIOLOGY
IF18.1
err2022-12-01
err5
errOAAI
errMoscat, Jorge; Linares, Juan F.; Duran, Angeles; Diaz-Meco, Maria T.
err分享
err收藏
The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62乳酸-NAD轴通过下调p62激活癌症相关成纤维细胞
errCELL REPORTS
IF6.9
err2022-05-01
err35
errOAAI
errLinares, Juan F.; Cid-Diaz, Tania; Duran, Angeles; Osrodek, Marta; Martinez-Ordonez, Anxo; Reina-Campos, Miguel; Kuo, Hui-Hsuan; Elemento, Olivier; Martin, M. Laura; Cordes, Thekla; Thompson, Timothy C.; Metallo, Christian M.; Moscat, Jorge; Diaz-Meco, Maria T.
err分享
err收藏
Immunosurveillance, interferon, and autophagic networking in cancer: the PRKCI-ULK2 paradigm
errAUTOPHAGY
IF14.3
err2021-12-12
err2
errOAAI
errMoscat, Jorge; Cuervo, Ana Maria; Diaz-Meco, Maria T.
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Michael Karin
H 指数: 254 · 论文数: 904
J
Johan Auwerx
H 指数: 183 · 论文数: 913
C
Christopher K. Glass
H 指数: 170 · 论文数: 569
G
Gregory J. Gores
H 指数: 164 · 论文数: 1.0K
B
Bart De Strooper
H 指数: 142 · 论文数: 686
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