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IL-4 drives exhaustion of CD8+ CART cells IL-4驱动CD8 CART细胞耗尽 Stewart, Carli M.; Siegler, Elizabeth L.; Sakemura, R. Leo; Cox, Michelle J.; Huynh, Truc; Kimball, Brooke; Mai, Long; Can, Ismail; Roman, Claudia Manriquez; Yun, Kun; Sirpilla, Olivia; Girsch, James H.; Ogbodo, Ekene; Ismail, Wazim Mohammed; Gaspar-Maia, Alexandre; Budka, Justin; Kim, Jenny; Scholler, Nathalie; Mattie, Mike; Filosto, Simone; Kenderian, Saad S. 分享 收藏
Medicinal evaluation and molecular docking study of osajin as an anti-inflammatory, antioxidant, and antiapoptotic agent against sepsis-associated acute kidney injury in rats Alhilal, Mohammad; Erol, Huseyin Serkan; Yildirim, Serkan; Cakir, Ahmet; Koc, Murat; Alhilal, Suzan; Dereli, Esra; Alkanoglu, Omer; Ay, Volkan; Can, Ismail; Halici, Mesut Bunyami 分享 收藏
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression Sirpilla, Olivia; Sakemura, R. Leo; Hefazi, Mehrdad; Huynh, Truc N.; Can, Ismail; Girsch, James H.; Tapper, Erin E.; Cox, Michelle J.; Schick, Kendall J.; Manriquez-Roman, Claudia; Yun, Kun; Stewart, Carli M.; Ogbodo, Ekene J.; Kimball, Brooke L.; Mai, Long K.; Gutierrez-Ruiz, Omar L.; Rodriguez, Makena L.; Gluscevic, Martina; Larson, Daniel P.; Abel, Alex M.; Wierson, Wesley A.; Olivier, Gloria; Siegler, Elizabeth L.; Kenderian, Saad S. 分享 收藏
Immunosuppressive monocytes suppress CART19 functions through modulation of the IL-1 pathway Yun, Kun; Sakemura, Reona; Truc Huynh; Roman, Claudia Manriquez; Sirpilla, Olivia; Stewart, Carli; Girsch, James; Ogbodo, Ekene; Can, Ismail; Feigin, Jennifer; Mai, Long; Xia, Hong; Kimball, Brooke; Rodriguez, Makena; Fonkoua, Lionel Kankeu; Hefazi, Mehrdad; Ruff, Michael; Siegler, Elizabeth; Kenderian, Saad 分享 收藏
IL-4 drives CART cell exhaustion in a CD4 independent manner Stewart, Carli M.; Siegler, Elizabeth L.; Huynh, Truc N.; Sakemura, R. Leo; Kimball, Brooke; Mai, Long; Yun, Kun; Girsch, James H.; Feigin, Jennifer; Ruiz, Omar Gutierrez; Rodriguez, Makena; Ogbodo, Ekene; Can, Ismail; Roman, Claudia Manriquez; Sirpilla, Olivia; Xia, Hong; Kim, Jenny; Budka, Justin; Mattie, Mike; Scholler, Nathalie; Filosto, Simone; Kenderian, Saad S. 分享 收藏
Tumor- derived microRNA125a induces CART cell apoptosis and failure in B cell malignancies Sirpilla, Olivia; Sakemura, R. Leo; Can, Ismail; Huynh, Truc N.; GIrsch, James H.; Roman, Claudia Manriquez; Stewart, Carli M.; Yun, Kun; Ogbodo, Ekene J.; Mai, Long; Ruiz, Omar Gutierrez; Rodriguez, Makena; Kimball, Brooke; Xia, Hong; Villasboas, Jose C.; Ansell, Stephen; Bennani, Nora; Johnston, Patrick B.; Paludo, Jonas; Castro, Januario; Kharfandabaja, Mohamed; Parikh, Sameer; Kay, Neil; Lin, Yi; Siegler, Elizabeth; Kenderian, Saad 分享 收藏
Frontline ibrutinib-based therapy enhances CART cell functions in patients with CLL: Analysis of the phase 3 randomized clinical trial ECOG-ACRIN E1912 Truc Ngoc Huynh; Wang, Victoria; Shanafelt, Tait; Siegler, Elizabeth L.; Stewart, Carli M.; Yun, Kun; Mai, Long K.; Sirpilla, Olivia; Girsch, James H.; Manriquez-Roman, Claudia; Feigin, Jennifer M.; Rodriguez, Makena; Kimball, Brooke L.; Xia, Hong; Sakemura, Reona L.; Can, Ismail; Gutierrez-Ruiz, Omar L.; Ogbodo, Ekene J.; Tapper, Erin E.; Fonkoua, Lionel A.; Hefazi, Mehrdad T.; Ruff, Michael W.; Parikh, Sameer; Kay, Neil E.; Kenderian, Saad J. 分享 收藏
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IL-4 depletion leads to the improvement of CART cell therapy Stewart, Carli; Cox, Michelle J.; Sakemura, Reona; Ogbodo, Ekene J.; Can, Ismail; Roman, Claudia Manriquez; Yun, Kun; Sirpilla, Olivia; Girsch, James H.; Huynh, Truc; Siegler, Elizabeth L.; Kim, Jenny J.; Mattie, Mike; Scholler, Nathalie; Filosto, Simone; Kenderian, Saad S. 分享 收藏
Impact of immunosuppressive monocytes on CART19 cell effector functions and outcomes Yun, Kun; Sakemura, Reona Leo; Cox, Michelle J.; Huynh, Truc; Manriquez-Roman, Claudia; Sirpilla, Olivia; Stewart, Carli M.; Girsch, James H.; Ogbodo, Ekene J.; Can, Ismail; Kimball, Brooke; Fonkoua, Lionel A. Kankeu; Hefazi, Mehrdad; Ruff, Michael W.; Siegler, Elizabeth L.; Mattie, Mike; Nguyen-Mau, Sao-Mai; Filosto, Simone; Kenderian, Saad S. 分享 收藏
Addition of MAPK inhibitors to prime and sensitize poorly differentiated thyroid cancers as a strategy to improve TSHR-CART cell therapy antitumor activity Roman, Claudia Manriquez; Schick, Kendall J.; Gleba, Justyna J.; Huynh, Truc N.; Siegler, Elizabeth L.; Miller, James L.; Demirer, Aylin Alasonyalilar; Pawlush, Matthew L.; Biligili, Ahmet; Mai, Long K.; Tapper, Erin; Sakemura, Leo R.; Cox, Michelle J.; Stewart, Carli M.; Can, Ismail; Ogbodo, Ekene J.; Cui, Gaofeng; Mer, Georges; Olivier, Gloria R.; Qiu, Yushi; Smallridge, Robert C.; Abba, Zubair C.; Tun, Han W.; Copland, John A.; Kenderian, Saad S. 分享 收藏
Simultaneous targeting of EphA3 on glioblastoma and tumor microenvironment to overcome resistance to CART cell therapy in brain cancer Ogbodo, Ekene J.; Ruff, Michael W.; Sakemura, Reona L.; ManriquezRoman, Claudia; Huynh, Truc; Girsch, James H.; Sirpilla, Olivia L.; Yun, Kun; Stewart, Carli M.; Can, Ismail; Fonkoua, Lionel K.; Hefazi, Mehrdad; Siegler, Elizabeth L.; Kenderian, Saad S. 分享 收藏
GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity Cox, Michelle J.; Roman, Claudia Manriquez; Tapper, Erin E.; Siegler, Elizabeth L.; Chappell, Dale; Durrant, Cameron; Ahmed, Omar; Sinha, Sutapa; Mwangi, Raphael; Scott, Nancy S.; Hefazi, Mehrdad; Schick, Kendall J.; Horvei, Paulina; Ruff, Michael W.; Can, Ismail; Adada, Mohamad; Bezerra, Evandro; Fonkoua, Lionel Aurelien Kankeu; Parikh, Sameer A.; Kay, Neil E.; Sakemura, Reona; Kenderian, Saad S. 分享 收藏
Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia Cox, Michelle J.; Lucien, Fabrice; Sakemura, Reona; Boysen, Justin C.; Kim, Yohan; Horvei, Paulina; Roman, Claudia Manriquez; Hansen, Michael J.; Tapper, Erin E.; Siegler, Elizabeth L.; Forsman, Cynthia; Crotts, Sydney B.; Schick, Kendall J.; Hefazi, Mehrdad; Ruff, Michael W.; Can, Ismail; Adada, Mohamad; Bezerra, Evandro; Fonkoua, Lionel Aurelien Kankeu; Nevala, Wendy K.; Braggio, Esteban; Ding, Wei; Parikh, Sameer A.; Kay, Neil E.; Kenderian, Saad S. 分享 收藏
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Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer Wagner, Alex H.; Devarakonda, Siddhartha; Skidmore, Zachary L.; Krysiak, Kilannin; Ramu, Avinash; Trani, Lee; Kunisaki, Jason; Masood, Ashiq; Waqar, Saiama N.; Spies, Nicholas C.; Morgensztern, Daniel; Waligorski, Jason; Ponce, Jennifer; Fulton, Robert S.; Maggi, Leonard B., Jr.; Weber, Jason D.; Watson, Mark A.; O'Conor, Christopher J.; Ritter, Jon H.; Olsen, Rachelle R.; Cheng, Haixia; Mukhopadhyay, Anandaroop; Can, Ismail; Cessna, Melissa H.; Oliver, Trudy G.; Mardis, Elaine R.; Wilson, Richard K.; Griffith, Malachi; Griffith, Obi L.; Govindan, Ramaswamy 分享 收藏
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