Graham Knott - Publications, H-index & Citations

Graham Knott

epfl

62H指数

257论文数

1.9W被引数

收录论文 64

发表时间

Modeling Parkinson’s pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity 利用人诱导多能干细胞来源的多巴胺能神经元模拟帕金森病病理，揭示了路易小体形成的关键机制和异质性

Science Advances

IF12.5

2026-07-10

OAAI

Anne-Laure Mahul-Mellier; Lukas van den Heuvel; Maxime Teixeira; Manel L. N. Boussouf; Gaspard Oudinot; Amélie Thonet; Davide Speri; Yllza Jasiqi; Christina Ulrich; Razan Sheta; Walid Idi; Mary Croisier; Stéphanie Clerc-Rosset; Jérôme Blanc; Graham Knott; Abid Oueslati; Hilal A. Lashuel

A microphysiological human mini-bladder reveals urine-urothelium interplay in tissue resilience and UPEC recurrence in urinary tract infections 微生理人类微型膀胱揭示了尿路感染中组织弹性和UPEC复发中的尿-尿路上皮相互作用

Nature Communications

IF15.7

2026-02-03

OAAI

Gauri Paduthol; Mikhail Nikolaev; Kunal Sharma; Jérôme Blanc; Kathrin Tomasek; Léa Ivana Esméralda Schlunke; Valentin Borgeat; Giovanna Ambrosini; Irina Kolotuev; Stéphanie Clerc-Rosset; Nikolche Gjorevski; Graham W. Knott; Matthias P. Lütolf; Vivek V. Thacker; John D. McKinney

Autophagy regulates PVALB (parvalbumin) interneuron excitability and memory 自噬调控PVALB（parvalbumin）中间神经元兴奋性和记忆

Autophagy

IF14.3

2025-12-14

OAAI

Theodora Chalatsi; Erin Wosnitzka; Angeliki Kolaxi; Laura M.J. Fernandez; Jules Scholler; Laura Batti; Leonardo Restivo; Graham Knott; Anita Lüthi; Manuel Mameli; Vassiliki Nikoletopoulou

Differential role of C-terminal truncations on alpha-synuclein pathology and Lewy body formation C-末端截断在α-突触核蛋白病理学和路易小体形成中的差异化作用

npj Parkinson's Disease

IF0

2025-08-26

OAAI

Anne-Laure Mahul-Mellier; Melek Firat Altay; Niran Maharjan; Nadine Ait-Bouziad; Anass Chiki; Somanath Jagannath; Galina Limorenko; Salvatore Novello; Jonathan Ricci; Yllza Jasiqi; Siv Vingill; Richard Wade-Martins; Janice Holton; Catherine Strand; Caroline Haikal; Jia-Yi Li; Romain Hamelin; Marie Croisier; Graham Knott; Georges Mairet-Coello; Laura Weerens; Anne Michel; Patrick Downey; Martin Citron; Hilal A. Lashuel

A sexually dimorphic hepatic cycle of periportal VLDL generation and subsequent pericentral VLDLR-mediated re-uptake

NATURE COMMUNICATIONS

IF15.7

2024-09-28

OAAI

Martini, Tomaz; Gobet, Cedric; Salati, Andrea; Blanc, Jerome; Mookhoek, Aart; Reinehr, Michael; Knott, Graham; Sordet-Dessimoz, Jessica; Naef, Felix

Stable isotope labeling and ultra-high-resolution NanoSIMS imaging reveal alpha-synuclein-induced changes in neuronal metabolism in vivo

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2023-09-29

OAAI

Spataro, Sofia; Maco, Bohumil; Escrig, Stephane; Jensen, Louise; Polerecky, Lubos; Knott, Graham; Meibom, Anders; Schneider, Bernard L.

Large-scale morphometry of the subarachnoid space of the optic nerve 视神经蛛网膜下腔的大规模形态计量学

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2023-03-21

OAAI

Rossinelli, Diego; Killer, Hanspeter Esriel; Meyer, Peter; Knott, Graham; Fourestey, Gilles; Kurtcuoglu, Vartan; Kohler, Corina; Gruber, Philipp; Remonda, Luca; Neutzner, Albert; Berberat, Jatta

Dynamics of CLIMP-63 S-acylation control ER morphology

NATURE COMMUNICATIONS

IF15.7

2023-01-17

OAAI

Sandoz, Patrick A.; Denhardt-Eriksson, Robin A.; Abrami, Laurence; Abriata, Luciano A.; Spreemann, Gard; Maclachlan, Catherine; Ho, Sylvia; Kunz, Beatrice; Hess, Kathryn; Knott, Graham; S. Mesquita, Francisco; Hatzimanikatis, Vassily; van der Goot, F. Gisou

Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau

NATURE COMMUNICATIONS

IF15.7

2022-08-27

OAAI

Asadzadeh, Jamshid; Ruchti, Evelyne; Jiao, Wei; Limoni, Greta; MacLachlan, Catherine; Small, Scott A.; Knott, Graham; Santa-Maria, Ismael; McCabe, Brian D.

ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

NATURE COMMUNICATIONS

IF15.7

2022-07-09

OAAI

Bernier-Latmani, Jeremiah; Mauri, Cristina; Marcone, Rachel; Renevey, Francois; Durot, Stephan; He, Liqun; Vanlandewijck, Michael; Maclachlan, Catherine; Davanture, Suzel; Zamboni, Nicola; Knott, Graham W.; Luther, Sanjiv A.; Betsholtz, Christer; Delorenzi, Mauro; Brisken, Cathrin; Petrova, Tatiana, V

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

COMMUNICATIONS BIOLOGY

IF5.1

2022-04-13

OAAI

Georgiou, Christina; Kehayas, Vassilis; Lee, Kok Sin; Brandalise, Federico; Sahlender, Daniela A.; Blanc, Jerome; Knott, Graham; Holtmaat, Anthony

Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties

NATURE COMMUNICATIONS

IF15.7

2021-11-12

OAAI

Riguet, Nathan; Mahul-Mellier, Anne-Laure; Maharjan, Niran; Burtscher, Johannes; Croisier, Marie; Knott, Graham; Hastings, Janna; Patin, Alice; Reiterer, Veronika; Farhan, Hesso; Nasarov, Sergey; Lashuel, Hilal A.

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

ELIFE

IF0

2021-07-05

OAAI

Sharma, Kunal; Dhar, Neeraj; Thacker, Vivek V.; Simonet, Thomas M.; Signorino-Gelo, Francois; Knott, Graham W.; McKinney, John D.

Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model

CELL REPORTS

IF6.9

2021-07-01

OAAI

Sharma, Kunal; Thacker, Vivek V.; Dhar, Neeraj; Cabrer, Maria Clapes; Dubois, Anaelle; Signorino-Gelo, Francois; Mullenders, Jasper; Knott, Graham W.; Clevers, Hans; McKinney, John D.

Mitofusin-2 in the Nucleus Accumbens Regulates Anxiety and Depression-like Behaviors Through Mitochondrial and Neuronal Actions

BIOLOGICAL PSYCHIATRY

IF9

2021-06-01

OAAI

Gebara, Elias; Zanoletti, Olivia; Ghosal, Sriparna; Grosse, Jocelyn; Schneider, Bernard L.; Knott, Graham; Astori, Simone; Sandi, Carmen

Toward Biophysical Mechanisms of Neocortical Computation after 50 Years of Barrel Cortex Research

FUNCTION

IF3.8

2020-12-21

OAAI

Petersen, Carl C. H.; Knott, Graham W.; Holtmaat, Anthony; Schuermann, Felix

Ultrastructural comparison of dendritic spine morphology preserved with cryo and chemical fixation

ELIFE

IF0

2020-12-04

OAAI

Tamada, Hiromi; Blanc, Jerome; Korogod, Natalya; Petersen, Carl Ch; Knott, Graham W.

Nano-imaging trace elements at organelle levels in substantia nigra overexpressing α-synuclein to model Parkinson's disease

COMMUNICATIONS BIOLOGY

IF5.1

2020-07-09

OAAI

Lemelle, Laurence; Simionovici, Alexandre; Colin, Philippe; Knott, Graham; Bohic, Sylvain; Cloetens, Peter; Schneider, Bernard L.

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

ELIFE

IF0

2020-06-23

OAAI

Contat, Caroline; Ancey, Pierre-Benoit; Zangger, Nadine; Sabatino, Silvia; Pascual, Justine; Escrig, Stephane; Jensen, Louise; Goepfert, Christine; Lanz, Bernard; Lepore, Mario; Gruetter, Rolf; Rossier, Anouk; Berezowska, Sabina; Neppl, Christina; Zlobec, Inti; Clerc-Rosset, Stephanie; Knott, Graham William; Rathmell, Jeffrey C.; Abel, E. Dale; Meibom, Anders; Meylan, Etienne

Somatostatin enhances visual processing and perception by suppressing excitatory inputs to parvalbumin-positive interneurons in V1

SCIENCE ADVANCES

IF12.5

2020-04-24

OAAI

Song, You-Hyang; Hwang, Yang-Sun; Kim, Kwansoo; Lee, Hyoung-Ro; Kim, Jae-Hyun; Maclachlan, Catherine; Dubois, Anaelle; Jung, Min Whan; Petersen, Carl C. H.; Knott, Graham; Lee, Suk-Ho; Lee, Seung-Hee

研究方向