Daniel A. Laheru - Publications, H-index & Citations

Daniel A. Laheru

johns hopkins university

77H指数

636论文数

3.6W被引数

收录论文 122

发表时间

Mutant KRAS peptide vaccine with dual checkpoint blockade in metastatic colorectal cancer: a phase I trial 携带KRAS突变肽疫苗及双重检查点封锁的转移性结直肠癌：一项I期临床试验

Nature Communications

IF15.7

2026-06-23

OAAI

Hejia Henry Wang; Amanda L. Huff; S. Daniel Haldar; Maureen Berg; Christopher Thoburn; Thatcher R. Heumann; Robert A. Anders; Benjamin Barrett; Katherine M. Bever; Michael J. Pishvaian; Valerie Lee; Dung T. Le; Eric S. Christenson; Marina Baretti; Mark Yarchoan; Daniel Laheru; Amy Thomas; Jennifer N. Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elizabeth M. Jaffee; Nilofer S. Azad; Neeha Zaidi

Publisher Correction: Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial Publisher Correction: 突变KRAS疫苗联合双重免疫检查点阻断在切除的胰腺癌中的I期临床试验

Nature Communications

IF15.7

2026-04-15

OAAI

Amanda L. Huff; S. Daniel Haldar; Alexander A. Girgis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W. Lee; Daniel H. Shu; Maximillian F. Konig; Brian J. Mog; Janelle Montagne; Erin M. Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A. Anders; Luciane T. Kagohara; Daniel Laheru; Amy M. Thomas; Jennifer Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elana J. Fertig; Won Jin Ho; Nilofer S. Azad; Elizabeth M. Jaffee; Neeha Zaidi

The combination of a cancer vaccine, pembrolizumab, and stereotactic body radiation in patients with locally advanced pancreatic cancer: a single-arm, phase II study 联合使用癌症疫苗、pembrolizumab 和立体定向体部放射治疗局部晚期胰腺癌患者的疗效：一项单臂、II 期研究

Nature Communications

IF15.7

2026-03-18

OAAI

Valerie Lee; Apoorvaa S. Sachidanand; Christina Rodriguez; Junke Wang; Beth Onners; Hanfei Qi; Rose Parkinson; Thomas McPhaul; Jennifer Durham; Ding Ding; Amy Hacker-Prietz; Amol K. Narang; Dung T. Le; Ana De Jesus; Michael Pishvaian; Eric Christenson; Elizabeth D. Thompson; Robert A. Anders; Arsen Osipov; Matthew Weiss; William Burns; Richard Burkhart; Kelly Lafaro; Jin He; Christopher L. Wolfgang; Elizabeth Sugar; Joseph M. Herman; Elizabeth M. Jaffee; Hao Wang; Daniel A. Laheru; Lei Zheng

Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial 携带双检查点阻断的突变KRAS疫苗在切除的胰腺癌中的应用：一项I期临床试验

Nature Communications

IF15.7

2026-02-10

OAAI

Amanda L. Huff; S. Daniel Haldar; Alexander A. Gergis; Hejia Henry Wang; Ludmila Danilova; Thatcher Heumann; Maureen Berg; Yuxuan Wang; Lalitya Andaloori; Alexei Hernandez; Gabriella Longway; Benjamin Barrett; Zirui Zhu; Emily Davis-Marcisak; Christopher Thoburn; James Leatherman; Sarah Mitchell; Jae W. Lee; Daniel H. Shu; Maximillian F. Konig; Brian J. Mog; Janelle Montagne; Erin M. Coyne; Katherine Bever; Marina Baretti; Mark Yarchoan; Robert A. Anders; Luciane T. Kagohara; Daniel Laheru; Amy M. Thomas; Jennifer Durham; Julie M. Nauroth; Jiayun Lu; Hao Wang; Elana J. Fertig; Won Jin Ho; Nilofer S. Azad; Elizabeth M. Jaffee; Neeha Zaidi

Pancreatic adenocarcinoma patients with pain have abnormal central pain processing 胰腺腺癌伴有疼痛的患者存在异常的中枢痛觉处理。

Pancreatology

IF2.7

2025-04-16

PREAI

Mahya Faghih; Marko Damm; Conrad Bandhauer; Josefine Jäger; Søren S. Olesen; Daniel A. Laheru; Lei Zheng; Anna E. Phillips; Dhiraj Yadav; Asbjørn M. Drewes; Jonas Rosendahl; Vikesh K. Singh

Phase 1 Study of Adjuvant Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor-Transduced Pancreatic Tumor Cell Vaccine, Low-Dose Cyclophosphamide, and Stereotactic Body Radiation Therapy Followed by FOLFIRINOX in High-Risk Resected Pancreatic Ductal Adenocarcinoma

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2025-03-01

PREAI

Hill, Colin S.; Parkinson, Rose; Jaffee, Elizabeth M.; Sugar, Elizabeth; Zheng, Lei; Onners, Beth; Weiss, Matthew J.; Wolfgang, Christopher L.; Cameron, John L.; Pawlik, Timothy M.; Rosati, Lauren; Le, Dung T.; Hacker-Prietz, Amy; Lutz, Eric R.; Schulick, Richard; Narang, Amol K.; Laheru, Daniel A.; Herman, Joseph M.

Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma

NATURE IMMUNOLOGY

IF27.6

2024-10-25

PREAI

Shu, Daniel H.; Ho, Won Jin; Kagohara, Luciane T.; Girgis, Alexander; Shin, Sarah M.; Danilova, Ludmila; Lee, Jae W.; Sidiropoulos, Dimitrios N.; Mitchell, Sarah; Munjal, Kabeer; Howe, Kathryn; Bendinelli, Kayla J.; Kartalia, Emma; Qi, Hanfei; Mo, Guanglan; Montagne, Janelle; Leatherman, James M.; Lopez-Vidal, Tamara Y.; Zhu, Qingfeng; Huff, Amanda L.; Yuan, Xuan; Hernandez, Alexei; Coyne, Erin M.; Zaidi, Neeha; Zabransky, Daniel J.; Engle, Logan L.; Ogurtsova, Aleksandra; Baretti, Marina; Laheru, Daniel; Durham, Jennifer N.; Wang, Hao; Sunshine, Joel C.; Johnston, Robert J.; Deutsch, Julie Stein; Taube, Janis M.; Anders, Robert A.; Jaffee, Elizabeth M.; Fertig, Elana J.; Yarchoan, Mark

An analysis of outcomes in patients (pts) with advanced pancreatic cancer (PDAC) whose tumors harbor pathogenic BRCA1 or BRCA2 mutations based on gene mutation location

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Hur, Jamie; McPhaul, Thomas; Cunningham, Dea; Zheng, Lei; Pishvaian, Christopher J.; Laheru, Daniel; De Jesus-Acosta, Ana; Le, Dung; Zaidi, Neeha; Azad, Nilo; Browner, Ilene; Burns, William R.; Burkhart, Richard; Lafaro, Kelly; Narang, Amol; He, Jin; Lee, Valerie; Brody, Jonathan R.; Pishvaian, Michael J.

Clinical outcomes of liposomal irinotecan in patients with advanced pancreatic cancer previously treated with conventional irinotecan: A meta-analysis of real-world evidence 脂质体伊立替康在先前接受常规伊立替康治疗的晚期胰腺癌患者中的临床结局: 真实世界证据的荟萃分析

CANCER

IF5.1

2024-07-10

PREAI

Gupta, Amol; De Jesus-Acosta, Ana; Le, Dung; Pishvaian, Michael; Zaidi, Neeha; Zheng, Lei; Laheru, Daniel

Mutant KRAS peptide-based vaccine in patients at high risk of developing pancreatic cancer: Preliminary analysis from a phase I study

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Haldar, Saurav D.; Huff, Amanda; Abou Diwan, Elizabeth; Ferguson, Anna; Judkins, Carol; Lu, Jiayun; Wang, Hao; Sinan, Hassan; Thoburn, Christopher; Bever, Katherine M.; Yarchoan, Mark; Thomas, Amy M.; Nauroth, Julie M.; Laheru, Daniel A.; Goggins, Michael G.; Jaffee, Elizabeth M.; Azad, Nilofer S.; Zaidi, Neeha

Safety and immunologic impact of neoadjuvant/adjuvant GM-CSFsecreting allogenic pancreatic tumor cell vaccine (GVAX) combined with cyclophosphamide, pembrolizumab, and macrophage-targeting CSF1R inhibitor IMC-CS4 in pancreatic adenocarcinoma

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Urman, Arielle; Ding, Yingjun; Wang, Hao; Burkhart, Richard A.; He, Jin; Jaffee, Elizabeth M.; Narang, Amol K.; Le, Dung; Laheru, Daniel A.; Zheng, Lei; De Jesus-Acosta, Ana

Identification of a novel morphology of tertiary lymphoid structure in patients with hepatocellular carcinoma treated with neoadjuvant immune checkpoint blockade

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Shu, Daniel H.; Ho, Won Jin; Kagohara, Luciane T.; Girgis, Alexander; Shin, Sarah M.; Danilova, Ludmila; Lee, Jae W.; Sidiropoulos, Dimitrios N. N.; Mitchell, Sarah; Munjal, Kabeer; Howe, Kathryn; Bendinelli, Kayla J.; Qi, Hanfei; Mo, Guanglan; Montagne, Janelle; Lopez-Vidal, Tamara Y.; Zhu, Qingfeng; Huff, Amanda L.; Yuan, Xuan; Hernandez, Alexei; Coyne, Erin M.; Zaidi, Neeha; Zabransky, Daniel J.; Engle, Logan L.; Ogurtsova, Aleksandra; Baretti, Marina; Laheru, Daniel; Durham, Jennifer N.; Wang, Hao; Anders, Robert; Jaffee, Elizabeth M.; Fertig, Elana J.; Yarchoan, Mark

Neoadjuvant radioimmunotherapy in pancreatic cancer enhances effector T cell infiltration and shortens their distances to tumor cells

SCIENCE ADVANCES

IF12.5

2024-02-09

OAAI

Wang, Junke; Gai, Jessica; Zhang, Tengyi; Niu, Nan; Qi, Hanfei; Thomas, Dwayne L.; Li, Keyu; Xia, Tao; Rodriguez, Christina; Parkinson, Rose; Durham, Jennifer; Mcphaul, Thomas; Narang, Amol K.; Anders, Robert A.; Osipov, Arsen; Wang, Hao; He, Jin; Laheru, Daniel A.; Herman, Joseph M.; Lee, Valerie; Jaffee, Elizabeth M.; Thompson, Elizabeth D.; Zhu, Qingfeng; Zheng, Lei

Controversies in upper GI oncology: maintenance treatment in pancreatic cancer

ESMO OPEN

IF8.3

2024-02-01

OAAI

Dekervel, J.; Laheru, D.; O'Reilly, E. M.

Tumor-infiltrating lymphocyte density correlates with survival in pancreatic adenosquamous carcinoma

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Haldar, Saurav D.; Jakubowski, Christopher D.; Lim, Su Jin; Wang, Hao; Burkhart, Richard A.; Lafaro, Kelly; Burns, William R., III; He, Jin; Laheru, Daniel A.; Thompson, Elizabeth D.; Azad, Nilofer S.

Meta-analysis of real-world survival outcomes of liposomal irinotecan in advanced pancreatic cancer patients with prior irinotecan exposure

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

OAAI

Gupta, A.; Laheru, D.

Clinical outcomes of liposomal irinotecan in advanced pancreatic adenocarcinoma patients previously treated with conventional irinotecan-based chemotherapy: a real-world study 脂质体伊立替康在先前接受基于伊立替康的常规化疗的晚期胰腺癌患者中的临床结果: 一项真实世界研究

FRONTIERS IN ONCOLOGY

IF3.3

2023-08-28

OAAI

Gupta, Amol; De Jesus-Acosta, Ana; Zheng, Lei; Lee, Valerie; Kamel, Ihab; Le, Dung; Pishvaian, Michael; Laheru, Daniel

A platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma 可切除胰腺腺癌患者新辅助和辅助抗肿瘤疫苗单独或联合PD-1拮抗剂和CD137激动剂抗体的平台试验

NATURE COMMUNICATIONS

IF15.7

2023-06-20

OAAI

Heumann, Thatcher; Judkins, Carol; Li, Keyu; Lim, Su Jin; Hoare, Jessica; Parkinson, Rose; Cao, Haihui; Zhang, Tengyi; Gai, Jessica; Celiker, Betul; Zhu, Qingfeng; McPhaul, Thomas; Durham, Jennifer; Purtell, Katrina; Klein, Rachel; Laheru, Daniel; De Jesus-Acosta, Ana; Le, Dung T.; Narang, Amol; Anders, Robert; Burkhart, Richard; Burns, William; Soares, Kevin; Wolfgang, Christopher; Thompson, Elizabeth; Jaffee, Elizabeth; Wang, Hao; He, Jin; Zheng, Lei

Safety and immunogenicity of a first-in-human mutant KRAS long peptide vaccine combined with ipilimumab/nivolumab in resected pancreatic cancer: Preliminary analysis from a phase I study

CANCER RESEARCH

IF16.6

2023-04-14

PREAI

Haldar, Saurav D.; Huff, Amanda; Heumann, Thatcher R.; Berg, Maureen; Ferguson, Anna; Lim, Su Jin; Wang, Hao; Thomas, Amy M.; Nauroth, Julie M.; Baretti, Marina; Bever, Katherine M.; Yarchoan, Mark; Laheru, Daniel A.; Jaffee, Elizabeth M.; Azad, Nilofer S.; Zaidi, Neeha

Phase I trial of intravenous mistletoe extract in advanced cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Paller, Channing J.; Wang, Lin; Fu, Wei; Kumar, Rajedra; Durham, Jennifer; Azad, Nilofer; Laheru, Daniel; Browner, Ilene; Kachhap, Sushant; Boyapati, Kavya; Odeny, Thomas; Armstrong, Deborah; Meyer, Christian; Gaillard, Stephanie; Brahmer, Julie; Page, Ivelisse; Wang, Hao; Diaz, Luis A.

研究方向