未登录 分享 收藏
O6-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo, and sensitivity to alisertib-carboplatin combination treatment O6-methylguanine DNA methyltransferase (MGMT) 在U1242胶质母细胞瘤细胞中的表达增强了体外克隆形成能力、体内肿瘤植入能力以及对阿利sertib-卡铂联合治疗的敏感性。 Sak, Muge; Williams, Brian J.; Hey, Andrew J.; Sharma, Mayur; Schier, Leslie; Wilson, Megan J.; Ortega, Mahatma; Lara, Alyssa I.; Brentlinger, Mikaela N.; Lehman, Norman L. 分享 收藏
分享 收藏
分享 收藏
Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 cases Wu, Zhichao; Dazelle, Karen; Abdullaev, Zied; Chung, Hye-Jung; Dahiya, Sonika; Wood, Matthew; Lee, Han; Lucas, Calixto-Hope G.; Mao, Qinwen; Robinson, Lorraina; Fernandes, Igor; McCord, Matthew; Pytel, Peter; Conway, Kyle S.; Yoda, Rebecca; Eschbacher, Jennifer M.; Maher, Ossama M.; Hasselblatt, Martin; Mobley, Bret C.; Raisanen, Jack M.; Hatanpaa, Kimmo J.; Byers, Joshua; Lehman, Norman L.; Cimino, Patrick J.; Pratt, Drew; Quezado, Martha; Aldape, Kenneth 分享 收藏
MicroRNA regulation of the serine synthesis pathway in endocrine-resistant breast cancer cells Petri, Belinda J.; Piell, Kellianne M.; Wilt, Ali E.; Howser, Alexa D.; Winkler, Laura; Whitworth, Mattie R.; Valdes, Bailey L.; Lehman, Norman L.; Clem, Brian F.; Klinge, Carolyn M. 分享 收藏
分享 收藏
分享 收藏
Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes Lehman, Norman L.; Spassky, Nathalie; Sak, Muge; Webb, Amy; Zumbar, Cory T.; Usubalieva, Aisulu; Alkhateeb, Khaled J.; McElroy, Joseph P.; Maclean, Kirsteen H.; Fadda, Paolo; Liu, Tom; Gangalapudi, Vineela; Carver, Jamie; Abdullaev, Zied; Timmers, Cynthia; Parker, John R.; Pierson, Christopher R.; Mobley, Bret C.; Gokden, Murat; Hattab, Eyas M.; Parrett, Timothy; Cooke, Ralph X.; Lehman, Trang D.; Costinean, Stefan; Parwani, Anil; Williams, Brian J.; Jensen, Randy L.; Aldape, Kenneth; Mistry, Akshitkumar M. 分享 收藏
HNRNPA2B1 regulates tamoxifen- and fulvestrant-sensitivity and hallmarks of endocrine resistance in breast cancer cells Petri, Belinda J.; Piell, Kellianne M.; Whitt, Gordon C. South; Wilt, Ali E.; Poulton, Claire C.; Lehman, Norman L.; Clem, Brian F.; Nystoriak, Matthew A.; Wysoczynski, Marcin; Klinge, Carolyn M. 分享 收藏
Cytotoxic synergy between alisertib and carboplatin versus alisertib and irinotecan are inversely dependent on MGMT levels in glioblastoma cells Sak, Muge; Zumbar, Cory T.; King, Paul D.; Li, Xiaohui; Mifsud, Caroline S.; Usubalieva, Aisulu; Anderson, Charles D.; Chesnick, Hailey M.; McElroy, Joseph P.; Chakravarti, Arnab; Burton, Eric C.; Lehman, Norman L. 分享 收藏
Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis Lehman, Norman L.; Usubalieva, Aisulu; Lin, Tong; Allen, Sariah J.; Tran, Quynh T.; Mobley, Bret C.; McLendon, Roger E.; Schniederjan, Matthew J.; Georgescu, Maria-Magdalena; Couce, Marta; Dulai, Mohanpal S.; Raisanen, Jack M.; Al Abbadi, Mousa; Palmer, Cheryl A.; Hattab, Eyas M.; Orr, Brent A. 分享 收藏
PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance Russell, Luke; Swanner, Jessica; Jaime-Ramirez, Alena Cristina; Wang, Yufeng; Sprague, Alex; Banasavadi-Siddegowda, Yeshavanth; Yoo, Ji Young; Sizemore, Gina M.; Kladney, Raleigh; Zhang, Jianying; Lehman, Norman L.; Ostrowski, Michael C.; Hong, Bangxing; Caligiuri, Michael; Yu, Jianhua; Kaur, Balveen 分享 收藏
Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair Sizemore, Steven T.; Zhang, Manchao; Cho, Ju Hwan; Sizemore, Gina M.; Hurwitz, Brian; Kaur, Balveen; Lehman, Norman L.; Ostrowski, Michael C.; Robe, Pierre A.; Miao, Weili; Wang, Yinsheng; Chakravarti, Arnab; Xia, Fen 分享 收藏
The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells Zumbar, Cory T.; Usubalieva, Aisulu; King, Paul D.; Li, Xiaohui; Mifsud, Caroline S.; Dalton, Hailey M.; Sak, Muge; Urio, Sara; Bryant, William M.; McElroy, Joseph P.; Farmer, George; Lehman, Norman L. 分享 收藏
分享 收藏
分享 收藏
Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults Lehman, Norman L.; Hattab, Eyas M.; Mobley, Bret C.; Usubalieva, Aisulu; Schniederjan, Matthew J.; McLendon, Roger E.; Paulus, Werner; Rushing, Elisabeth J.; Georgescu, Maria-Magdalena; Couce, Marta; Dulai, Mohanpal S.; Cohen, Mark L.; Pierson, Christopher R.; Raisanen, Jack M.; Martin, Sarah E.; Lehman, Trang D.; Lipp, Eric S.; Bonnin, Jose M.; Al-Abbadi, Mousa A.; Kenworthy, Kara; Zhao, Kevin; Mohamed, Nehad; Zhang, Guojuan; Zhao, Weiqiang 分享 收藏
NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors Georgescu, Maria-Magdalena; Mobley, Bret C.; Orr, Brent A.; Shang, Ping; Lehman, Norman L.; Zhu, Xiaoping; O'Neill, Thomas J.; Rajaram, Veena; Hatanpaa, Kimmo J.; Timmons, Charles F.; Raisanen, Jack M. 分享 收藏
分享 收藏
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png)
OAAI
.png){kind=icon}
分享.png){kind=icon}
收藏