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艾华松 封面图

艾华松 (Huasong Ai)

shanghai jiao tong university

19H指数
54论文数
1.3K被引数
收录论文 32
发表时间
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Steric Gating Contributes to the Preferential Ubiquitin Charging of BIRC6 by UBA6 versus UBA1空间位阻调节有助于UBA6相较于UBA1对BIRC6的泛素选择性加载
errNature Communications
IF15.7
err2026-08-29
err0
errOAAI
errZebin Tong; Rujing Yuan; Xiangwei Wu; Hongyi Cai; Ziyu Xu; Lei Liu; Huasong Ai
err分享
err收藏
Huasong Ai艾华松
errAngewandte Chemie-International Edition
IF16.9
err2026-07-27
err0
errOAAI
errHuasong Ai
err分享
err收藏
Ferricyanide-mediated direct ligation of peptide hydrazides in neutral water铁氰化物介导的肽肼在中性水中的直接连接
errNature Synthesis
IF20
err2026-07-24
err0
PREAI
errDongyang Han; Xianglai Zhu; Guiyu Deng; Wei He; Tianyi Zhang; Huasong Ai; Guo-Chao Chu; Lei Liu
err分享
err收藏
Chemically Synthesized H3K14Ub Unveils Clr4's IDR-Mediated Multivalent Nucleosome Recognition in H3K9 Methylation化学合成的H3K14Ub揭示了Clr4在H3K9甲基化中IDR介导的多价核小体识别
errAngewandte Chemie International Edition
IF16.9
err2026-03-24
err0
PREAI
errMaoshen Sun; Yunxiang Du; Zhengqing Li; Akejiang Aderjiang; Meixuan Xin; Huasong Ai
err分享
err收藏
Development of Substrate-Directed Activity-Based Probes via Disulfide-Trapping for Site-Specific Interrogation of Nucleosomal Deubiquitination通过二硫键捕获法开发基质导向的活性基探针，用于对核小体去泛素化的位点特异性探查
errJournal of the American Chemical Society
IF15.6
err2026-02-07
err0
PREAI
errZaozhen He; Yuantong Huo; Yanling Zhang; Shixian Tao; Yun Liu; Zhiheng Deng; Xiaolin Tian; Xinyu Lan; Haiteng Deng; Lei Liu; Wei Qin; Huasong Ai
err分享
err收藏
Unique gluing effect of ASXL1 K351 monoubiquitination stimulates the PR-DUB activityASXL1 K351单泛素化的独特胶合效应刺激PR-DUB活性
errNature Chemical Biology
IF13.7
err2026-01-09
err0
PREAI
errTianyi Zhang; Jiqing Zheng; Zebing Tong; Zhiheng Deng; Zaozhen He; Xiangwei Wu; Miao Wang; Yunxiang Du; Ziyu Xu; Shixian Tao; Shizhang Wan; Xiaolin Tian; Haiteng Deng; Man Pan; Huasong Ai; Lei Liu
err分享
err收藏
Chemical strategies for trapping fleeting enzymatic complexes in nucleosome ubiquitylation化学策略捕获核小体泛素化中短暂存在的酶复合物
errCurrent Opinion in Chemical Biology
IF6.1
err2026-01-07
err0
errOAAI
errYun Liu; Qi Shu; Huasong Ai
err分享
err收藏
Allosteric activation of RNF20/RNF40–RAD6A-mediated H2BK120 monoubiquitylation by H2BS112 GlcNAcylationRNF20/RNF40–RAD6A介导的H2BK120单泛素化的别构激活由H2BS112 GlcNAcylation介导。
errNature Chemical Biology
IF13.7
err2026-01-06
err0
PREAI
errZhiheng Deng; Shixian Tao; Yunxiang Du; Yulei Li; Liying Zhang; Qiang Shi; Xiaoru Du; Maoshen Sun; Zebin Tong; Man Pan; Lei Liu; Huasong Ai
err分享
err收藏
Structural basis for E4 enzyme Ufd2-catalyzed K48/K29 branched ubiquitin chainsE4酶Ufd2催化的K48/K29分支泛素链的结构基础
errNature Chemical Biology
IF13.7
err2025-08-15
err0
PREAI
errZebin Tong; Xiangwei Wu; Hongyi Cai; Shidian Wu; Tianyi Zhang; Zhiheng Deng; Ziyu Xu; Rujing Yuan; Huasong Ai; Lei Liu; Man Pan
err分享
err收藏
Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring ubiquitin to form K29/K48-branched polyubiquitinationHECT型E3连接酶Ufd4接受并转移泛素以形成K29/K48-分支多泛素化的结构可视化
errNATURE COMMUNICATIONS
IF15.7
err2025-05-09
err1
errOAAI
errWu, Xiangwei; Ai, Huasong; Mao, Junxiong; Cai, Hongyi; Liang, Lu-Jun; Tong, Zebin; Deng, Zhiheng; Zheng, Qingyun; Liu, Lei
err分享
err收藏
The Emerging Role of the Histone H2AK13/15 Ubiquitination: Mechanisms of Writing, Reading, and Erasing in DNA Damage Repair and Disease
errCELLS
IF5.2
err2025-02-18
err0
errOAAI
errShu, Qi; Liu, Yun; Ai, Huasong
err分享
err收藏
RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-01-01
err2
PREAI
errZhang, Liying; Deng, Zhiheng; Du, Yunxiang; Xu, Ziyu; Zhang, Tianyi; Tong, Zebin; Ai, Huasong; Liang, Lu-Jun; Liu, Lei
err分享
err收藏
Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally Defined K63-Polyubiquitylated Linker Histone H1
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-11-06
err0
PREAI
errShi, Qiang; Deng, Zhiheng; Zhang, Liying; Tong, Zebin; Li, Jia-Bin; Chu, Guo-Chao; Ai, Huasong; Liu, Lei
err分享
err收藏
Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-10-11
err2
PREAI
errAi, Huasong; Tong, Zebin; Deng, Zhiheng; Shi, Qiang; Tao, Shixian; Sun, Gaoge; Liang, Jiawei; Sun, Maoshen; Wu, Xiangwei; Zheng, Qingyun; Liang, Lujun; Yin, Hang; Li, Jia-Bin; Gao, Shuai; Tian, Changlin; Liu, Lei; Pan, Man
err分享
err收藏
Ferricyanide-Promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media中性水性介质中铁氰化物促进的蛋白质硫代酸的氧化活化和连接
errCCS CHEMISTRY
IF9.2
err2024-08-01
err7
PREAI
errChu, Guo-Chao; Liang, Lu-Jun; Zhao, Rui; Guo, Yan-Yan; Li, Chun-Tong; Zuo, Chong; Ai, Huasong; Hua, Xiao; Li, Zi-Chen; Li, Yi-Ming; Liu, Lei
err分享
err收藏
Chemical Synthesis of Human Proteoforms and Application in Biomedicine
errACS CENTRAL SCIENCE
IF10.4
err2024-07-22
err7
errOAAI
errAi, Huasong; Pan, Man; Liu, Lei
err分享
err收藏
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-06-25
err1
PREAI
errAi, Huasong; He, Zaozhen; Deng, Zhiheng; Chu, Guo-Chao; Shi, Qiang; Tong, Zebin; Li, Jia-Bin; Pan, Man; Liu, Lei
err分享
err收藏
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-01-04
err9
errOAAI
errTong, Zebin; Ai, Huasong; Xu, Ziyu; He, Kezhang; Chu, Guo-Chao; Shi, Qiang; Deng, Zhiheng; Xue, Qiaomei; Sun, Maoshen; Du, Yunxiang; Liang, Lujun; Li, Jia-Bin; Pan, Man; Liu, Lei
err分享
err收藏
Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A酵母Bre1-Rad6及其人类同源物RNF20/RNF40-hRAD6A介导的核小体H2B单碱基化的机理研究
errMOLECULAR CELL
IF16.6
err2023-09-01
err14
errOAAI
errDeng, Zhiheng; Ai, Huasong; Sun, Maoshen; Tong, Zebin; Du, Yunxiang; Qu, Qian; Zhang, Liying; Xu, Ziyu; Tao, Shixian; Shi, Qiang; Li, Jia-Bin; Pan, Man; Liu, Lei
err分享
err收藏
Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination
errCHEM
IF19.6
err2023-05-01
err26
errOAAI
errAi, Huasong; Tong, Zebin; Deng, Zhiheng; Tian, Jiakun; Zhang, Liying; Sun, Maoshen; Du, Yunxiang; Xu, Ziyu; Shi, Qiang; Liang, Lujun; Zheng, Qingyun; Li, Jia-Bin; Pan, Man; Liu, Lei
err分享
err收藏

研究方向

表观遗传修饰的化学方法与探针工具开发表观修饰的功能机制解析表观遗传相关疾病药物靶点干预与调控
合作学者
合作期刊
刘
刘磊 (Lei Liu)
H 指数: 82 · 论文数: 578
邓
邓海腾 (Haiteng Deng)
H 指数: 81 · 论文数: 470
H
Hang Yin
H 指数: 69 · 论文数: 428
华
华霄 (Hua Xiao)
H 指数: 64 · 论文数: 387
刘贇 封面图
刘贇 (Yun Liu)
H 指数: 60 · 论文数: 710
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