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顾

顾颖 (Ying Gu)

affiliated women's hospital of jiangnan university
H指数:38
被引数:4,945

个人简介

"顾颖，博士 GU Ying, Ph.D. 副教授，硕士生导师 Associate Professor 简历 (Education and Work experience) 1996年，厦门大学生物学专业，学士学位； 2006年，厦门大学生化与分子生物学专业/细胞生物学专业，博士学位； 2006年，厦门大学生命科学学院助理教授、硕士生导师； 2013年，厦门大学生命科学学院副教授； B.S. Biochemistry, Xiamen University, 2000 Ph.D. Biochemistry & Molecular Biology/Cell Biology, Xiamen University, 2006 Assistant Professor, School of Life Sciences, Xiamen University, 2006 Associate Professor, School of Life Sciences, Xiamen University, 2013 荣誉、奖励及参加学术团体的情况(Honors and award) 主持3项国家自然科学基金项目、1项国家科技重大专项子课题，1项福建省科技重大项目，并作为主要参与人参加多项国家级、省部级重大重点科研项目；获得中国高校科技进步一等奖（2001），国家技术发明二等奖（2010），中国专利金奖（2012），厦门市科学技术进步一等奖（2010），厦门大学第四届青年教师教学技能比赛一等奖（2008），厦门大学第三届青年教师教学技能比赛二等奖（2007）。申请发明专利11项，国际发明专利8项，获得授权4项；为主参与研制戊肝疫苗、宫颈癌疫苗、艾滋诊断试剂等新药。 WIPO-SIPO Award for Chinese Outstanding Patented Invention (2012) State Technological Invention Award (2010)"

教育背景

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工作经历

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荣誉奖项

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Single cell multiomics revealed fibrotic trajectories of endometrial cells and interaction with the pro-fibrotic macrophages in intrauterine adhesion

单细胞多组学揭示了子宫内膜细胞的纤维化轨迹及其与促纤维化巨噬细胞的相互作用，在宫腔粘连中的作用。

Genome Medicine
IF11.2
2026-04-070
OAAI
Yu Li; Wei Wu; Houyi Lv; Libing Shi; Zhuomin Wang; Chengcheng Zhu; Junwen Zhang; Xilin Shen; Yiyuan Qu; Wanwan Xu; Shunxian Ji; Ying Gu; Mohammad Ishraq Zafar; Yingying Hu; Xiao Chen; Xiaofeng Zhao; Songying Zhang; Jian Xu; Bingbing Wu
The crucial but insufficient role of E2s domain’s residues 490 and 492 in determining the host tropism of hepatitis E virus

E2s结构域残基490和492在决定戊型肝炎病毒宿主嗜性方面的关键但不足的作用

Nature Communications
IF15.7
2026-02-090
OAAI
Zi-Min Tang; Cheng-Yu Yang; Gui-Ping Wen; Chang Liu; Dong Ying; Yang Huang; Zi-Hao Yu; Ming-Yu Li; Si-Ling Wang; Zi-Hao Chen; Jun-Fei Liu; Mu-Jin Fang; Ying-Bin Wang; Jun Zhang; Ying Gu; Hai Yu; Shao-Wei Li; Qing-Bing Zheng; Ning-Shao Xia; Zi-Zheng Zheng
Engineering a multivalent antibody nanoparticle to overcome SARS-CoV-2 Omicron immune evasion

设计一种多价抗体纳米颗粒以克服SARS-CoV-2 Omicron免疫逃逸

PLOS PATHOGENS
IF4.9
2025-12-080
PRE
Sun, Hui; Jiang, Yanan; Lan, Miaolin; Zhou, Ming; Yi, Gangshun; Shen, Juan; Deng, Tingting; Liu, Liqin; Huang, Yang; Li, Yu; Su, Jinfu; Lin, Yanling; Chen, Zhenqin; Zhou, Lizhi; Li, Tingting; Yu, Hai; Cheng, Tong; Zhang, Yali; Yuan, Lunzhi; Li, Shaowei; Gu, Ying; Zhang, Peijun; Xia, Ningshao; Zheng, Qingbing
Nanobody-based combination vaccine using licensed protein nanoparticles protects animals against respiratory and viral infections

基于许可蛋白纳米颗粒的纳米抗体组合疫苗可保护动物免受呼吸道和病毒感染。

Nature Biomedical Engineering
IF26.6
2025-10-240
PRE
Tingting Li; Wenhui Xue; Sibo Zhang; Hong Wang; Miaolin Lan; Limin Zhang; Min Lin; Ming Zhou; Dong Ying; Yarong Zeng; Lingyan Cui; Yifan Yin; Huiqing Chen; Jian Ma; Chang Liu; Jijing Chen; Chen Wang; Zihao Yu; Yanling Chen; Yangtao Wu; Hongjing Liu; Hai Li; Yuyun Zhang; Jinjin Li; Zhen Lu; Zihao Chen; Yali Zhang; Lunzhi Yuan; Lizhi Zhou; Qingbing Zheng; Hai Yu; Jun Zhang; Tong Cheng; Junyu Chen; Yixin Chen; Yi Guan; Zizheng Zheng; Ying Gu; Ningshao Xia; Shaowei Li
Structural insight into broadening SARS-CoV-2 neutralization by an antibody cocktail harbouring both NTD and RBD potent antibodies

通过包含NTD和RBD强效抗体的抗体鸡尾酒扩大SARS-CoV-2中和的结构见解

EMERGING MICROBES & INFECTIONS
IF7.5
2024-11-270
OAAI
Jiang, Wenling; Jiang, Yanan; Sun, Hui; Deng, Tingting; Yu, Kunyu; Fang, Qianjiao; Ge, Huimin; Lan, Miaoling; Lin, Yanling; Fang, Zhongyue; Zhang, Yali; Zhou, Lizhi; Li, Tingting; Yu, Hai; Zheng, Qingbing; Li, Shaowei; Xia, Ningshao; Gu, Ying
Structural basis for the synergetic neutralization of hepatitis E virus by antibody-antibody interaction

抗体-抗体相互作用协同中和戊型肝炎病毒的结构基础

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-11-250
PRE
Zheng, Minghua; Zhou, Lizhi; Huang, Yang; Zhang, Xiao; Yu, Zihao; Yang, Chengyu; Chen, Yuanzhi; Ying, Dong; Wang, Hong; Chen, Zhenqin; Liu, Chang; Tang, Zimin; Wang, Siling; Wang, Kaihang; Yang, Kaixiang; Lin, Yanqing; Li, Tingting; Zheng, Qingbing; Zheng, Zizheng; Zhang, Jun; Yu, Hai; Li, Shaowei; Gu, Ying; Xia, Ningshao
Rational design of a cross-type HPV vaccine through immunodominance shift guided by a cross-neutralizing antibody

通过交叉中和抗体指导的免疫优势转移合理设计交叉型HPV疫苗

SCIENCE BULLETIN
IF21.1
2024-02-011
OAAI
Wang, Zhiping; Wang, Daning; Chen, Jie; Gao, Fei; Jiang, Yanan; Yang, Chengyu; Qian, Ciying; Chi, Xin; Zhang, Shuyue; Xu, Yujie; Lu, Yihan; Shen, Jingjia; Zhang, Chengzong; Li, Jinjin; Zhou, Lizhi; Li, Tingting; Zheng, Qingbing; Yu, Hai; Li, Shaowei; Xia, Ningshao; Gu, Ying
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD

两种抗体通过诱导RBD内的构象变化对SARS-CoV-2变体显示出广泛的协同中和作用

PROTEIN & CELL
IF12.8
2023-07-203
OAAI
Sun, Hui; Deng, Tingting; Zhang, Yali; Lin, Yanling; Jiang, Yanan; Jiang, Yichao; Huang, Yang; Song, Shuo; Cui, Lingyan; Li, Tingting; Xiong, Hualong; Lan, Miaolin; Liu, Liqin; Li, Yu; Fang, Qianjiao; Yu, Kunyu; Jiang, Wenling; Zhou, Lizhi; Que, Yuqiong; Zhang, Tianying; Yuan, Quan; Cheng, Tong; Zhang, Zheng; Yu, Hai; Zhang, Jun; Luo, Wenxin; Li, Shaowei; Zheng, Qingbing; Gu, Ying; Xia, Ningshao

研究方向

抗病毒单抗筛选识别免疫优势表位单抗等的筛选基于表位的抗原研究功能性表位研究：应用生物传感器分析超离抗原-抗体的相互作用研究免疫复合物的空间结构解析功能性表位的特征鉴定HIV中和单克隆抗体生成广谱中和活性抗体研究病毒抗原关键表位的鉴定与表征表位功能表征表位作图结构分析抗体-抗原复合物结构测定
李
李少伟
H 指数:44论文数:337被引数:7,942
Ningshao Xia 封面图
Ningshao Xia
H 指数:82论文数:1,000被引数:3.0万
Q
Qingbing Zheng
H 指数:30论文数:167被引数:3,026
张军 封面图
张军
H 指数:71论文数:1,009被引数:2.4万
H
Hai Yu
H 指数:30论文数:139被引数:3,081
T
Tingting Li
H 指数:25论文数:82被引数:4,026
Q
Qinjian Zhao
H 指数:39论文数:181被引数:5,714
L
Lizhi Zhou
H 指数:13论文数:84被引数:520
M
Maozhou He
H 指数:17论文数:39被引数:709
D
Daning Wang
H 指数:20论文数:85被引数:1,319