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Scott A. Armstrong

dana-farber cancer institute and boston children's hospital and harvard medical school

92H指数
657论文数
4.0W被引数
收录论文 141
发表时间
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Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues泛素化位点不依赖的KAT2A招募扩展了CRBN分子胶的目标空间
errScience
IF45.8
err2026-07-09
err0
PREAI
errSamuel Ojeda; Meng Wang; Kheewoong Baek; Wallace Bourgeois; Alba Sommerschield; Hong Yue; Rebecca J. Metivier; Panos Karagiannis; Talya S. Levitz; Yuan Xiong; Katherine A. Donovan; Scott A. Armstrong; Eric S. Fischer
err分享
err收藏
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trialsCRISPR碱基编辑筛选确定了影响临床试验中menin抑制剂的MEN1突变谱
errNature Communications
IF15.7
err2026-05-09
err0
errOAAI
errWallace Bourgeois; Hannah E. Rice; Daniela V. Wenge; Florian Perner; Hong Yue; Brandon D. Regalado; George Wan; Jan C. Schroeder; Alba Sommerschield; Charlie Hatton; Shivendra Singh; Sweta Singh; Shipra Bijpuria; Brian M. McKeever; William H. Miller; Jordan F. Safer; Sumaiya Iqbal; Jennifer A. Perry; Eric S. Fischer; John G. Doench; Gerard M. McGeehan; Jevon A. Cutler; Scott A. Armstrong
err分享
err收藏
Epigenetic Therapies
errCold Spring Harbor Perspectives in Medicine
IF10.1
err2026-03-01
err3
PREAI
errBourgeois, Wallace; Armstrong, Scott A.; Heikamp, Emily B.
err分享
err收藏
High-throughput ligand diversification to discover chemical inducers of proximity高通量配体多样化以发现邻近性的化学诱导剂
errNature Chemical Biology
IF13.7
err2026-02-16
err0
errOAAI
errJames B. Shaum; Miquel Muñoz i Ordoño; Erica A. Steen; Daniela V. Wenge; Hakyung Cheong; Jordan Janowski; Moritz Hunkeler; Eric M. Bilotta; Zoe J. Rutter; Paige A. Barta; Abby M. Thornhill; Natalia Milosevich; Lauren M. Hargis; Timothy R. Bishop; Trever R. Carter; Bryce da Camara; Matthias Hinterndorfer; Lucas Dada; Wen-Ji He; Fabian Offensperger; Hirotake Furihata; Sydney R. Schweber; Charlie Hatton; Yanhe Wen; Benjamin F. Cravatt; Keary M. Engle; Katherine A. Donovan; Bruno Melillo; Seiya Kitamura; Alessio Ciulli; Scott A. Armstrong; Eric S. Fischer; Georg E. Winter; Michael A. Erb
err分享
err收藏
Quantitative homogenization and large-scale regularity of Poisson point clouds泊松点云的定量均匀化与大规模正则性
errStochastics and Partial Differential Equations: Analysis and Computations
IF0
err2026-01-01
err0
PREAI
errScott Armstrong; Raghavendra Venkatraman
err分享
err收藏
Renormalization group and elliptic homogenization in high contrast重整化群与高对比度下的椭圆同伦化
errInventiones mathematicae
IF3.6
err2025-09-25
err0
PREAI
errScott Armstrong; Tuomo Kuusi
err分享
err收藏
Menin inhibition for the treatment of acute leukemiaMenin抑制在急性白血病治疗中的应用
errSeminars in Hematology
IF4.1
err2025-08-14
err0
PREAI
errDaniela V. Wenge; Scott A. Armstrong
err分享
err收藏
An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis体内条形码CRISPR-Cas9筛选鉴定出Ncoa4介导的铁蛋白自噬是Tet2缺陷型造血的依赖因素
errBlood
IF23.1
err2025-06-16
err0
errOAAI
errJustin Loke; Peter G. Kim; Thuy T. P. Nguyen; Meaghan Boileau; Marie McConkey; Aidan Miller; Wesley Shin; Christopher B. Hergott; Maria Ericsson; Anja Nordstrom; Paula Montero Llopis; Scott A. Armstrong; Joseph D. Mancias; Benjamin L. Ebert
err分享
err收藏
Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer联合抑制KAT6A/B和Menin可逆转乳腺癌中雌激素受体驱动的基因表达程序
errCell Reports Medicine
IF10.6
err2025-06-13
err0
errOAAI
errSarah Naomi Olsen; Bryn Anderson; Charlie Hatton; Zhengtao Chu; Christopher Simpkins; Yanhe Wen; Wallace Bourgeois; Elena L. Haarer; Myles Brown; Rinath Jeselsohn; Alana L. Welm; Eneda Toska; Scott A. Armstrong
err分享
err收藏
Targeting the Menin-KMT2A interaction in leukemia: Lessons learned and future directions针对白血病的Menin-KMT2A相互作用: 经验教训和未来方向
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2025-01-30
err0
errOAAI
errPerner, Florian; Gadrey, Jayant Y.; Armstrong, Scott A.; Kuehn, Michael W. M.
err分享
err收藏
Optimal Convergence Rates for the Spectrum of the Graph Laplacian on Poisson Point Clouds图拉普拉斯算子谱在泊松点云上的最优收敛速率
errFOUNDATIONS OF COMPUTATIONAL MATHEMATICS
IF2.7
err2025-01-22
err0
PREAI
errArmstrong, Scott; Venkatraman, Raghavendra
err分享
err收藏
Transient Menin Inhibition Is Sufficient to Induce Irreversible Polycomb-Mediated Silencing and Potent Anti-Proliferative Effects in MLL-Rearranged AML瞬时Menin抑制足以诱导MLL重排AML中表观遗传沉默（Polycomb介导）和强烈的抗增殖效应
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errNeville, Daniel; Ferguson, Daniel; Heikamp, Emily; Bell, Charles; Armstrong, Scott A.; Gilan, Omer
err分享
err收藏
The Histone Acetyltransferase MOZ (KAT6A) Is a Molecular Dependency and Therapeutic Target in NUP98-Rearranged Acute Myeloid Leukemia组蛋白乙酰转移酶MOZ（KAT6A）是NUP98重排急性髓系白血病中的分子依赖性和治疗靶点
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMichmerhuizen, Nicole L.; Heikamp, Emily; Umeda, Masayuki; Iacobucci, Ilaria; Arthur, Bright; Di Giacomo, Danika; Hiltenbrand, Ryan; Radko-Juettner, Sandi; Portola, Pablo; Claquin, Aurelie; Chandra, Bappaditya; Baggett, David W.; Huang, Hongling; Zhou, Peipei; Long, Lingyun; Shi, Hao; Sun, Yu; Papachristou, Evangelia K.; Chilamakuri, Chandra Sekhar Reddy; Vitorino, Francisca N. de L.; Gongora, Joanna M.; D'Santos, Clive S.; Garcia, Benjamin A.; Kriwacki, Richard W.; Chi, Hongbo; Kentsis, Alex; Armstrong, Scott A.; Klco, Jeffery M.; Mullighan, Charles G.
err分享
err收藏
Discerning the Landscape of Menin Inhibitor Resistance鉴别Menin抑制剂耐药性的景观
errBLOOD
IF23.1
err2024-11-05
err1
PREAI
errBourgeois, Wallace; Cutler, Jevon; Rice, Hannah E.; Regalado, Brandon; Wenge, Daniela, V; Perner, Florian; Doench, John G.; Mcgeehan, Jerry M.; Armstrong, Scott A.
err分享
err收藏
NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AML
errCELL REPORTS
IF6.9
err2024-11-01
err0
errOAAI
errHeikamp, Emily B.; Martucci, Cynthia; Henrich, Jill A.; Neel, Dana S.; Mahendra-Rajah, Sanisha; Rice, Hannah; Wenge, Daniela, V; Perner, Florian; Wen, Yanhe; Hatton, Charlie; Armstrong, Scott A.
err分享
err收藏
A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-06-18
err2
errOAAI
errSmolko, Anne E.; Sullivan, Daniel W.; Olsen, Sarah Naomi; Kang, Hyuckjoon; Whedon, Samuel D.; Baell, Jonathan B.; Cole, Philip A.; Armstrong, Scott A.; Kuroda, Mitzi I.
err分享
err收藏
KAT6A/B and Menin-MLL complexes coordinately regulate estrogen receptor-driven gene expression programs in breast cancer
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-06-10
err0
PREAI
errOlsen, Sarah Naomi; Anderson, Bryn; Hatton, Charles; Jeselsohn, Rinath; Brown, Myles; Toska, Eneda; Armstrong, Scott
err分享
err收藏
KAT6A/B and Menin-MLL complexes coordinately regulate estrogen receptor-driven gene expression programs in breast cancer
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-06-10
err0
PREAI
errOlsen, Sarah Naomi; Anderson, Bryn; Hatton, Charles; Jeselsohn, Rinath; Brown, Myles; Toska, Eneda; Armstrong, Scott
err分享
err收藏
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells
errCANCER DISCOVERY
IF33.3
err2024-05-30
err1
PREAI
errWaarts, Michael R.; Mowla, Shoron; Boileau, Meaghan; Benitez, Anthony R. Martinez; Sango, Junya; Bagish, Maya; Fernandez-Maestre, Ines; Shan, Yufan; Eisman, Shira E.; Park, Young C.; Wereski, Matthew; Csete, Isabelle; O'Connor, Kavi; Romero-Vega, Angelica C.; Miles, Linde A.; Xiao, Wenbin; Wu, Xiaodi; Koche, Richard P.; Armstrong, Scott A.; Shih, Alan H.; Papapetrou, Eirini P.; Butler, Jason M.; Cai, Sheng F.; Bowman, Robert L.; Levine, Ross L.
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err收藏
Epitope editing enables targeted immunotherapy of acute myeloid leukemia
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errCasirati, Gabriele; Cosentino, Andrea; Mucci, Adele; Mahmoud, Mohammed S.; Zabala, Iratxe Ugarte; Zeng, Jing; Ficarro, Scott B.; Klatt, Denise; Brendel, Christian; Rambaldi, Alessandro; Ritz, Jerome; Marto, Jarrod A.; Pellin, Danilo; Bauer, Daniel E.; Armstrong, Scott A.; Genovese, Pietro
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
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H 指数: 220 · 论文数: 938
K
Kenneth C. Anderson
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Mark A. Rubin
H 指数: 186 · 论文数: 1.5K
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