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LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization LRRK2相关帕金森病伴有及不伴有体内α-突触核蛋白聚集物证据：纵向临床与生物标志物特征 Chahine, Lana M.; Lafontant, David-Erick; Choi, Seung Ho; Iwaki, Hirotaka; Blauwendraat, Cornelis; Singleton, Andrew B.; Brumm, Michael C.; Alcalay, Roy N.; Merchant, Kalpana; Nudelman, Kelly Nicole Holohan; Dagher, Alain; Vo, Andrew; Tao, Qin; Venuto, Charles S.; Kieburtz, Karl; Poston, Kathleen L.; Bressman, Susan; Gonzalez-Latapi, Paulina; Avants, Brian; Coffey, Christopher; Jennings, Danna; Tolosa, Eduardo; Siderowf, Andrew; Marek, Ken; Simuni, Tatyana; Parkinsons Progression Markers Initiative, Kenneth 分享 收藏
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CVN424, a GPR6 inverse agonist, for Parkinson's ' s disease and motor fl uctuations: a double-blind, randomized, phase 2 trial Brice, Nicola L.; Carlton, Mark; Margolin, David H.; Bexon, Martin; Matthews, Kim L.; Dawson, Lee A.; Ellenbogen, Aaron L.; Olanow, C. Warren; Dubow, Jordan; Kieburtz, Karl 分享 收藏
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Continuous Levodopa Delivery with an Intraoral Micropump System: An Open-Label Pharmacokinetics and Clinical Study Olanow, C. Warren; Mcintyre, Deborah; Matarazzo, Michele; Leinonen, Mika; McGarry, Andrew; Kamp, Cornelia; Kennedy, Julie; Torti, Margherita; Kruger, Rejko; Obeso, Jose A.; Stocchi, Fabrizio; Heller, Ephraim; Kieburtz, Karl 分享 收藏
Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative 十二年的药物优先次序，以帮助加速帕金森病的疾病改善试验: 国际链接临床试验倡议 Wyse, Richard K.; Isaacs, Tom; Barker, Roger A.; Cookson, Mark R.; Dawson, Ted M.; Devos, David; Dexter, David T.; Duffen, Joy; Federoff, Howard; Fiske, Brian; Foltynie, Thomas; Fox, Susan; Greenamyre, J. Timothy; Kieburtz, Karl; Kordower, Jeffrey H.; Krainc, Dimitri; Matthews, Helen; Moore, Darren J.; Mursaleen, Leah; Schwarzschild, Michael A.; Stott, Simon R. W.; Sulzer, David; Svenningsson, Per; Tanner, Caroline M.; Carroll, Camille; Simon, David K.; Brundin, Patrik 分享 收藏
Dry-Cleaning Chemicals and a Cluster of Parkinson's Disease and Cancer: A Retrospective Investigation Dorsey, E. Ray; Kinel, Dan; Pawlik, Meghan E.; Zafar, Maryam; Lettenberger, Samantha E.; Coffey, Madeleine; Auinger, Peggy; Hylton, Kevin L.; Shaw, Carol W.; Adams, Jamie L.; Barbano, Richard; Braun, Melanie K.; Schwarz, Heidi B.; Lawrence, B. Paige; Kieburtz, Karl; Tanner, Caroline M.; de Miranda, Briana R.; Goldman, Samuel M. 分享 收藏
A Randomized Phase 3 Study Comparing P2B001 to its Components (Low-Dose Extended-Release Rasagiline and Pramipexole) and to Optimized Doses of Marketed Extended-Release Pramipexole in Early Parkinson's Disease Olanow, C. Warren; Hauser, Robert A.; Burdick, Daniel J.; Dhall, Rohit; de Marcaida, Joy Antonelle; Gil, Ramon A.; Kreitzman, David L.; Elmer, Lawrence W.; Mcgarry, Andrew; Kieburtz, Karl 分享 收藏
Parkinson's Progression Markers Initiative: A Milestone-Based Strategy to Monitor Parkinson's Disease Progression Brumm, Michael C.; Siderowf, Andrew; Simuni, Tanya; Burghardt, Elliot; Choi, Seung Ho; Caspell-Garcia, Chelsea; Chahine, Lana M.; Mollenhauer, Brit; Foroud, Tatiana; Galasko, Douglas; Merchant, Kalpana; Arnedo, Vanessa; Hutten, Samantha J.; O'Grady, Alyssa N.; Poston, Kathleen L.; Tanner, Caroline M.; Weintraub, Daniel; Kieburtz, Karl; Marek, Kenneth; Coffey, Christopher S. 分享 收藏
Trichloroethylene: An Invisible Cause of Parkinson's Disease? Dorsey, E. Ray; Zafar, Maryam; Lettenberger, Samantha E.; Pawlik, Meghan E.; Kinel, Dan; Frissen, Myrthe; Schneider, Ruth B.; Kieburtz, Karl; Tanner, Caroline M.; De Miranda, Briana R.; Goldman, Samuel M.; Bloem, Bastiaan R. 分享 收藏
Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial (Aug, 10.1038/s41591-022-01919-8, 2022) Feigin, Andrew; Evans, Elizabeth E.; Fisher, Terrence L.; Leonard, John E.; Smith, Ernest S.; Reader, Alisha; Mishra, Vikas; Manber, Richard; Walters, Kimberly A.; Kowarski, Lisa; Oakes, David; Siemers, Eric; Kieburtz, Karl D.; Zauderer, Maurice 分享 收藏
SYNTHESIS OF KEY RESULTS AND CONCLUSIONS OF THE SIGNAL PHASE 2 STUDY OF PEPINEMAB AS A TREATMENT FOR EARLY HD Zauderer, Maurice; Evans, Elizabeth; Fisher, Terry; Mishra, Vikas; Leonard, John; Oakes, David; Walters, Kimberly; Kowarski, Lisa; Siemers, Eric; Kieburtz, Karl; Feigin, Andrew 分享 收藏
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Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial Feigin, Andrew; Evans, Elizabeth E.; Fisher, Terrence L.; Leonard, John E.; Smith, Ernest S.; Reader, Alisha; Mishra, Vikas; Manber, Richard; Walters, Kimberly A.; Kowarski, Lisa; Oakes, David; Siemers, Eric; Kieburtz, Karl D.; Zauderer, Maurice 分享 收藏
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Subcutaneous Levodopa Infusion for Parkinson's Disease: 1-Year Data from the Open-Label BeyoND Study 帕金森氏病的皮下左旋多巴输注: 开放标签BeyoND研究的1年数据 Poewe, Werner; Stocchi, Fabrizio; Arkadir, David; Ebersbach, Georg; Ellenbogen, Aaron L.; Giladi, Nir; Isaacson, Stuart H.; Kieburtz, Karl; LeWitt, Peter; Olanow, C. Warren; Simuni, Tanya; Thomas, Astrid; Zlotogorski, Abraham; Adar, Liat; Case, Ryan; Oren, Sheila; Orenbach, Shir Fuchs; Rosenfeld, Olivia; Sasson, Nissim; Yardeni, Tami; Espay, Alberto J. 分享 收藏
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Seeking progress in disease modification in Parkinson disease Lungu, Codrin; Cedarbaum, Jesse M.; Dawson, Ted M.; Dorsey, E. Ray; Faraco, Carlos; Federoff, Howard J.; Fiske, Brian; Fox, Robert; Goldfine, Andrew M.; Kieburtz, Karl; Macklin, Eric A.; Matthews, Helen; Rafaloff, Gary; Saunders-Pullman, Rachel; Schor, Nina F.; Schwarzschild, Michael A.; Sieber, Beth-Anne; Simuni, Tanya; Surmeier, Dalton J.; Tamiz, Amir; Werner, Milton H.; Wright, Clinton B.; Wyse, Richard 分享 收藏
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