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M

Michaël Mingueneau

biogen inc
H指数:28
被引数:2,741

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Leveraging Kinase Drugs for Neurosciences: Discovery of Selective; CNS-Penetrant Reversible Bruton’s Tyrosine Kinase Inhibitors as Therapeutics for Neuroinflammation

利用激酶药物进行神经科学研究：发现选择性、能穿透中枢神经系统的可逆性布鲁顿酪氨酸激酶抑制剂作为神经炎症的治疗方法

Journal of Medicinal Chemistry
IF6.8
2026-04-070
OA
Brian T. Hopkins; Isaac E. Marx; Harlod George Vandeveer; Marta Nevalainen; Rebecca Basile; Bekim Bajrami; Colin K. Choi; Richard J. Grater; Chungang Gu; Marc Hoemberger; Ekta Kadakia; Sudarshan K. Kapadnis; Ying Liu; Bin Ma; Tom Magee; Claire M. Metrick; Michael Mingueneau; Cathy A. Muste; Chelsea R. Parker Harp; Robin J. Prince; Joseph C. Santoro; Jurgen Schulz; Simone Sciabola; Hao Tang; Ti Wang; Robert Meissner; Tonika Bohnert
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-05-073
OAAI
Himmelbauer, Martin K.; Bajrami, Bekim; Basile, Rebecca; Capacci, Andrew; Chen, Teyu; Choi, Colin K.; Gilfillan, Rab; de Turiso, Felix Gonzalez-Lopez; Gu, Chungang; Hoemberger, Marc; Johnson, Douglas S.; Jones, J. Howard; Kadakia, Ekta; Kirkland, Melissa; Lin, Edward Y.; Liu, Ying; Ma, Bin; Magee, Tom; Mantena, Srinivasa; Marx, Isaac E.; Metrick, Claire M.; Mingueneau, Michael; Murugan, Paramasivam; Muste, Cathy A.; Nadella, Prasad; Nevalainen, Marta; Parker Harp, Chelsea R.; Pattaropong, Vatee; Pietrasiewicz, Alicia; Prince, Robin J.; Purgett, Thomas J.; Santoro, Joseph C.; Schulz, Jurgen; Sciabola, Simone; Tang, Hao; Vandeveer, H. George; Wang, Ti; Yousaf, Zain; Helal, Christopher J.; Hopkins, Brian T.
Oxidative phosphorylation regulates B cell effector cytokines and promotes inflammation in multiple sclerosis

氧化磷酸化调节b细胞效应细胞因子并促进多发性硬化症的炎症

SCIENCE IMMUNOLOGY
IF16.3
2024-05-031
PRE
Li, Rui; Lei, Yanting; Rezk, Ayman; Espinoza, Diego A.; Wang, Jing; Feng, Huiru; Zhang, Bo; Barcelos, Isabella P.; Zhang, Hang; Yu, Jing; Huo, Xinrui; Zhu, Fangyi; Yang, Changxin; Tang, Hao; Goldstein, Amy C.; Banwell, Brenda L.; Hakonarson, Hakon; Xu, Hongwei; Mingueneau, Michael; Sun, Bo; Li, Hulun; Bar-Or, Amit
Variability of Primary Sjogren's Syndrome Is Driven by Interferon α and Interferon α Blood Levels Are Associated With the Class II HLA-DQ Locus
ARTHRITIS & RHEUMATOLOGY
IF10.9
2022-11-0225
OA
Trutschel, Diana; Bost, Pierre; Mariette, Xavier; Bondet, Vincent; Llibre, Alba; Posseme, Celine; Charbit, Bruno; Thorball, Christian W.; Jonsson, Roland; Lessard, Christopher J.; Felten, Renaud; Ng, Wan Fai; Chatenoud, Lucienne; Dumortier, Helene; Sibilia, Jean; Fellay, Jacques; Brokstad, Karl A.; Appel, Silke; Tarn, Jessica R.; Quintana-Murci, Lluis; Mingueneau, Michael; Meyer, Nicolas; Duffy, Darragh; Schwikowski, Benno; Gottenberg, Jacques Eric
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-11-0421
PREAI
Hopkins, Brian T.; Bame, Eris; Bajrami, Bekim; Black, Cheryl; Bohnert, Tonika; Boiselle, Carrie; Burdette, Doug; Burns, Jeremy C.; Delva, Luisette; Donaldson, Douglas; Grater, Richard; Gu, Chungang; Hoemberger, Marc; Johnson, Josh; Kapadnis, Sudarshan; King, Kris; Lulla, Mukesh; Ma, Bin; Marx, Isaac; Magee, Tom; Meissner, Robert; Metrick, Claire M.; Mingueneau, Michael; Murugan, Paramasivam; Otipoby, Kevin L.; Polack, Evelyne; Poreci, Urjana; Prince, Robin; Roach, Allie M.; Rowbottom, Chris; Santoro, Joseph C.; Schroeder, Patricia; Tang, Hao; Tien, Eric; Zhang, Fengmei; Lyssikatos, Joseph
MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response

MOG自身抗体触发严格控制的FcR和BTK驱动的小胶质细胞增殖反应

BRAIN
IF11.7
2021-06-1940
OA
Pellerin, Kathryn; Rubino, Stephen J.; Burns, Jeremy C.; Smith, Benjamin A.; Mccarl, Christie-Ann; Zhu, Jing; Jandreski, Luke; Cullen, Patrick; Carlile, Thomas M.; Li, Angela; Rebollar, Jorge Vera; Sybulski, Jennifer; Reynolds, Taylor L.; Zhang, Baohong; Basile, Rebecca; Tang, Hao; Harp, Chelsea Parker; Pellerin, Alex; Silbereis, John; Franchimont, Nathalie; Cahir-McFarland, Ellen; Ransohoff, Richard M.; Cameron, Thomas O.; Mingueneau, Michael
Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

器官型脑切片培养小胶质细胞与急性分离的成年小胶质细胞具有分子相似性，并提供了研究神经炎症的平台

FRONTIERS IN CELLULAR NEUROSCIENCE
IF4
2020-12-2141
OAAI
Delbridge, Alex R. D.; Huh, Dann; Brickelmaier, Margot; Burns, Jeremy C.; Roberts, Chris; Challa, Ravi; Raymond, Naideline; Cullen, Patrick; Carlile, Thomas M.; Ennis, Katelin A.; Liu, Mei; Sun, Chao; Allaire, Normand E.; Foos, Marianna; Tsai, Hui-Hsin; Franchimont, Nathalie; Ransohoff, Richard M.; Butts, Cherie; Mingueneau, Michael
ImmGen at 15
NATURE IMMUNOLOGY
IF27.6
2020-06-2350
OAAI
Aguilar, Stephanie Vargas; Aguilar, Oscar; Allan, Rhys; Amir, El Ad David; Angeli, Veronique; Artyomov, Maxim N.; Asinovski, Natasha; Astarita, Jilian; Austen, K. Frank; Bajpai, Geetika; Barrett, Nora; Baysoy, Alev; Benoist, Christophe; Bellemare-Pelletier, Angelique; Berg, Brad; Best, Adam; Bezman, Natalie; Blair, David; Blander, Julie M.; Bogunovic, Milena; Brennan, Patrick; Brenner, Michael; Brown, Brian; Buechler, Matthew; Buenrostro, Jason; Casanova, Maria Acebes; Choi, Kyunghee; Chow, Andrew; Chudnovskiy, Aleksey; Cipoletta, Daniela; Cohen, Nadia; Collins, James J.; Colonna, Marco; Cook, Alison; Costello, James; Cremasco, Viviana; Crowl, Ty; Crozat, Karine; Cruse, Richard; D'Angelo, June; Dalod, Marc; Davis, Scott; Demiralp, Cagatay; Deng, Tianda; Desai, Jigar, V; Desland, Fiona; Dhainaut, Maxime; Ding, Jiarui; Doedens, Andrew; Dominguez, Claudia; Doran, Graeme; Dress, Regine; Dustin, Michael; Dwyer, Daniel; Dzhagalov, Ivan; Elpek, Kutlu; Ergun, Ayla; Ericson, Jeff; Esomonu, Eunice; Fairfax, Keke; Fletcher, Anne; Frascoli, Michela; Fuchs, Anja; Gainullina, Anastasiia; Gal-Oz, Shani; Gallagher, Michael; Gautier, Emmanuel; Gazit, Roi; Gibbings, Sophie; Giraud, Matthieu; Ginhoux, Florent; Goldrath, Ananda; Gotthardt, Dagmar; Gray, Daniel; Greter, Melanie; Grieshaber-Bouyer, Ricardo; Guilliams, Martin; Haidermota, Sara; Hardy, Randy; Hashimoto, Daigo; Helft, Julie; Hendricks, Deborah; Heng, Tracy; Hill, Jonathan; Hyatt, Gordon; Idoyaga, Juliana; Jakubzick, Claudia; Jarjoura, Jessica; Jepson, Daniel; Jia, Baosen; Jianu, Radu; Johanson, Tim; Jordan, Stefan; Jojic, Vladimir; Jordan, Stefan; Kamimura, Yosuke; Kana, Veronica; Kang, Joonsoo; Kapoor, Varun; Kenigsberg, Ephriam; Kent, Andrew; Kim, Charles; Kim, Edy; Kim, Francis; Kim, Joel; Kim, Kiwook; Kiner, Evgeny; Knell, Jamie; Koller, Daphne; Kozinn, Larry; Krchma, Karen; Kreslavsky, Taras; Kronenberg, Mitchell; Kwan, Wing-Hong; Laidlaw, David; Lam, Viola; Lanier, Lewis; Laplace, Catherine; Lareau, Caleb; Lavin, Yonit; Lavine, Kory J.; Leader, Andrew; Leboeuf, Marylene; Lee, Jacob; Lee, Jisu; Li, Bo; Li, Hu; Li, Yuesheng; Lionakis, Michail S.; Luche, Herve; Lynch, Lydia; Magen, Assaf; Maier, Barbara; Malhotra, Deepali; Malhotra, Nidhi; Malissen, Marie; Maslova, Alexandra; Mathis, Diane; McFarland, Adelle; Merad, Miriam; Meunier, Etienne; Miller, Jennifer; Milner, Justin; Mingueneau, Michael; Min-Oo, Gundula; Monach, Paul; Moodley, Devapregasan; Mortha, Arthur; Morvan, Maelig; Mostafavi, Sara; Muller, Soren; Muus, Christoph; Nabekura, Tsukasa; Rao, Tata Nageswara; Narang, Vipin; Narayan, Kavitha; Ner-Gaon, Hadas; Nguyen, Quyhn; Nigrovic, Peter A.; Novakovsky, German; Nutt, Stephan; Omilusik, Kayla; Ortiz-Lopez, Adriana; Paidassi, Helena; Paik, Henry; Painter, Michio; Paynich, Mallory; Peng, Vincent; Potempa, Marc; Pradhan, Rachana; Price, Jeremy; Qi, Yilin; Qi, Yiqing; Quon, Sara; Ramirez, Ricardo; Ramanan, Deepshika; Randolph, Gwendalyn; Regev, Aviv; Rhoads, Andrew; Robinette, Michelle; Rose, Samuel; Rossi, Derrick; Rothamel, Katie; Sachidanandam, Ravi; Sathe, Priyanka; Scott, Charlotte; Seddu, Kumba; See, Peter; Sergushichev, Alexey; Shaw, Laura; Shay, Tal; Shemesh, Avishai; Shinton, Susan; Shyer, Justin; Sieweke, Michael; Smillie, Chris; Spel, Lotte; Spidale, Nick; Stifano, Giuseppina; Subramanian, Ayshwarya; Sun, Joseph; Sylvia, Katelyn; Tellier, Julie; This, Sebastien; Tomasello, Elena; Todorov, Helena; Turley, Shannon; Vijaykumar, Brinda; Wagers, Amy; Wakamatsu, Ei; Wang, Chendi; Wang, Peter L.; Wroblewska, Aleksandra; Wu, Jun; Yang, Edward; Yang, Liang; Yim, Aldrin; Yng, Lim Sheau; Yoshida, Hideyuki; Yu, Bingfei; Zhou, Yan; Zhu, Yanan; Ziemkiewicz, Caroline

研究方向

暂未获取到该数据
M
Marie Malissen
H 指数:60论文数:196被引数:1.1万
B
Bernard Malissen
H 指数:109论文数:820被引数:4.7万
T
Taylor L. Reynolds
H 指数:19论文数:71被引数:1,702
H
Hao Tang
H 指数:30论文数:160被引数:4,035
J
Jeremy C. Burns
H 指数:11论文数:18被引数:587
X
Xavier Mariette
H 指数:110论文数:1,030被引数:5.2万
G
Gaëtane Nocturne
H 指数:33论文数:260被引数:5,196
R
Romain Roncagalli
H 指数:25论文数:47被引数:2,633
C
Christophe Benoıst
H 指数:21论文数:103被引数:2,730
B
Brian T. Hopkins
H 指数:15论文数:32被引数:829