William C. Chang

walter reed army institute of research

H指数:18

被引数:1,083

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Production of Clinical-Grade SARS-CoV-2 Spike Ferritin Nanoparticle Protein Immunogen by Transient Transfection

通过瞬时转染生产临床级SARS-CoV-2 Spike Ferritin Nanoparticle Protein免疫原

Vaccines

IF3.4

2026-03-030

OAAI

Agnes Hajduczki; William C. Chang; Rafael De La Barrera; James F. Wood; Wei-Hung Chen; Elizabeth J. Martinez; Jaime L. Jensen; Rajeshwer S. Sankhala; Clayton Smith; Alexander Anderson; Elaine B. Morrison; Caroline E. Peterson; Phyllis A. Rees; Sandrine Soman; Caitlin Kuklis; Aslaa Ahmed; Jocelyn King; Farooq Nasar; Courtney Corbitt; Misook Choe; Paul V. Thomas; Michelle Zemil; Lindsay Wieczorek; Victoria R. Polonis; Helen M. Dooley; John R. Mascola; Natalie de Val; Gary R. Matyas; Mangala Rao; Gregory D. Gromowski; Kayvon Modjarrad; Sandhya Vasan; Jeffrey W. Froude; Nelson L. Michael; M. Gordon Joyce; Stasya Zarling

Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

NATURE COMMUNICATIONS

IF15.7

2024-01-033

OAAI

Sankhala, Rajeshwer S.; Lal, Kerri G.; Jensen, Jaime L.; Dussupt, Vincent; Mendez-Rivera, Letzibeth; Bai, Hongjun; Wieczorek, Lindsay; Mayer, Sandra V.; Zemil, Michelle; Wagner, Danielle A.; Townsley, Samantha M.; Hajduczki, Agnes; Chang, William C.; Chen, Wei-Hung; Donofrio, Gina C.; Jian, Ningbo; King, Hannah A. D.; Lorang, Cynthia G.; Martinez, Elizabeth J.; Rees, Phyllis A.; Peterson, Caroline E.; Schmidt, Fabian; Hart, Tricia J.; Duso, Debra K.; Kummer, Lawrence W.; Casey, Sean P.; Williams, Jazmean K.; Kannan, Shruthi; Slike, Bonnie M.; Smith, Lauren; Swafford, Isabella; Thomas, Paul V.; Tran, Ursula; Currier, Jeffrey R.; Bolton, Diane L.; Davidson, Edgar; Doranz, Benjamin J.; Hatziioannou, Theodora; Bieniasz, Paul D.; Paquin-Proulx, Dominic; Reiley, William W.; Rolland, Morgane; Sullivan, Nancy J.; Vasan, Sandhya; Collins, Natalie D.; Modjarrad, Kayvon; Gromowski, Gregory D.; Polonis, Victoria R.; Michael, Nelson L.; Krebs, Shelly J.; Joyce, M. Gordon

Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers

PHARMACEUTICS

IF5.5

2023-11-275

OAAI

Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity

JOURNAL OF VIROLOGY

IF3.8

2023-07-2712

OAAI

Jensen, Jaime L.; Sankhala, Rajeshwer S.; Dussupt, Vincent; Bai, Hongjun; Hajduczki, Agnes; Lal, Kerri G.; Chang, William C.; Martinez, Elizabeth J.; Peterson, Caroline E.; Golub, Emily S.; Rees, Phyllis A.; Mendez-Rivera, Letzibeth; Zemil, Michelle; Kavusak, Erin; Mayer, Sandra V.; Wieczorek, Lindsay; Kannan, Shruthi; Doranz, Benjamin J.; Davidson, Edgar; Yang, Eun Sung; Zhang, Yi; Chen, Man; Choe, Misook; Wang, Lingshu; Gromowski, Gregory D.; Koup, Richard A.; Michael, Nelson L.; Polonis, Victoria R.; Rolland, Morgane; Modjarrad, Kayvon; Krebs, Shelly J.; Joyce, M. Gordon

Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques

CELL REPORTS MEDICINE

IF10.6

2023-04-014

OAAI

Yu, Jingyou; Thomas, Paul V.; Sciacca, Michaela; Wu, Cindy; Liu, Jinyan; He, Xuan; Miller, Jessica; Hachmann, Nicole P.; Surve, Nehalee; McMahan, Katherine; Jacob-Dolan, Catherine; Powers, Olivia; Hall, Kevin; Barrett, Julia; Hope, David; Mazurek, Camille R.; Murdza, Tetyana; Chang, William C.; Golub, Emily; Rees, Phyllis A.; Peterson, Caroline E.; Hajduczki, Agnes; Chen, Wei-Hung; Martinez, Elizabeth J.; Hussin, Elizabeth; Lange, Camille; Gong, Hua; Matyas, Gary R.; Rao, Mangala; Suthar, Mehul; Boursiquot, Mona; Cook, Anthony; Pessaint, Laurent; Lewis, Mark G.; Andersen, Hanne; Bolton, Diane L.; Michael, Nelson L.; Joyce, M. Gordon; Modjarrad, Kayvon; Barouch, Dan H.

SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies

NPJ VACCINES

IF6.5

2023-03-1812

OAAI

Shrivastava, Shikha; Carmen, Joshua M.; Lu, Zhongyan; Basu, Shraddha; Sankhala, Rajeshwer S.; Chen, Wei-Hung; Nguyen, Phuong; Chang, William C.; King, Jocelyn; Corbitt, Courtney; Mayer, Sandra; Bolton, Jessica S.; Anderson, Alexander; Swafford, Isabella; Terriquez, Guillermo D.; Trinh, Hung V.; Kim, Jiae; Jobe, Ousman; Paquin-Proulx, Dominic; Matyas, Gary R.; Gromowski, Gregory D.; Currier, Jeffrey R.; Bergmann-Leitner, Elke; Modjarrad, Kayvon; Michael, Nelson L.; Joyce, M. Gordon; Malloy, Allison M. W.; Rao, Mangala

Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity

NATURE COMMUNICATIONS

IF15.7

2023-02-0316

OAAI

Chen, Wei-Hung; Hajduczki, Agnes; Martinez, Elizabeth J.; Bai, Hongjun; Matz, Hanover; Hill, Thomas M.; Lewitus, Eric; Chang, William C.; Dawit, Layla; Peterson, Caroline E.; Rees, Phyllis A.; Ajayi, Adelola B.; Golub, Emily S.; Swafford, Isabella; Dussupt, Vincent; David, Sapna; Mayer, Sandra V.; Soman, Sandrine; Kuklis, Caitlin; Corbitt, Courtney; King, Jocelyn; Choe, Misook; Sankhala, Rajeshwer S.; Thomas, Paul V.; Zemil, Michelle; Wieczorek, Lindsay; Hart, Tricia; Duso, Debora; Kummer, Larry; Yan, Lianying; Sterling, Spencer L.; Laing, Eric D.; Broder, Christopher C.; Williams, Jazmean K.; Davidson, Edgar; Doranz, Benjamin J.; Krebs, Shelly J.; Polonis, Victoria R.; Paquin-Proulx, Dominic; Rolland, Morgane; Reiley, William W.; Gromowski, Gregory D.; Modjarrad, Kayvon; Dooley, Helen; Joyce, M. Gordon

Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN

SCIENCE ADVANCES

IF12.5

2022-11-234

OAAI

Yu, Jingyou; Thomas, Paul, V; McMahan, Katherine; Jacob-Dolan, Catherine; Liu, Jinyan; He, Xuan; Hope, David; Martinez, Elizabeth J.; Chen, Wei -Hung; Sciacca, Michaela; Hachmann, Nicole P.; Lifton, Michelle; Miller, Jessica; Powers, Olivia C.; Hall, Kevin; Wu, Cindy; Barrett, Julia; Swafford, Isabella; Currier, Jeffrey R.; King, Jocelyn; Corbitt, Courtney; Chang, William C.; Golub, Emily; Rees, Phyllis A.; Peterson, Caroline E.; Hajduczki, Agnes; Hussin, Elizabeth; Lange, Camille; Gong, Hua; Matyas, Gary R.; Rao, Mangala; Paquin-Proulx, Dominic; Gromowski, Gregory D.; Lewis, Mark G.; Andersen, Hanne; Davis-Gardner, Meredith; Suthar, Mehul S.; Michael, Nelson L.; Bolton, Diane L.; Joyce, M. Gordon; Modjarrad, Kayvon; Barouch, Dan H.

A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model

VACCINES

IF3.4

2022-05-0420

OAAI

Johnston, Sara C.; Ricks, Keersten M.; Lakhal-Naouar, Ines; Jay, Alexandra; Subra, Caroline; Raymond, Jo Lynne; King, Hannah A. D.; Rossi, Franco; Clements, Tamara L.; Fetterer, David; Tostenson, Samantha; Cincotta, Camila Macedo; Hack, Holly R.; Kuklis, Caitlin; Soman, Sandrine; King, Jocelyn; Peachman, Kristina K.; Kim, Dohoon; Chen, Wei-Hung; Sankhala, Rajeshwer S.; Martinez, Elizabeth J.; Hajduczki, Agnes; Chang, William C.; Choe, Misook; Thomas, Paul, V; Peterson, Caroline E.; Anderson, Alexander; Swafford, Isabella; Currier, Jeffrey R.; Paquin-Proulx, Dominic; Jagodzinski, Linda L.; Matyas, Gary R.; Rao, Mangala; Gromowski, Gregory D.; Peel, Sheila A.; White, Lauren; Smith, Jeffrey M.; Hooper, Jay W.; Michael, Nelson L.; Modjarrad, Kayvon; Joyce, M. Gordon; Nalca, Aysegul; Bolton, Diane L.; Pitt, Margaret L. M.

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-02-1694

Joyce, M. Gordon; King, Hannah A. D.; Elakhal-Naouar, Ines; Ahmed, Aslaa; Peachman, Kristina K.; Cincotta, Camila Macedo; Subra, Caroline; Chen, Rita E.; Thomas, Paul, V; Chen, Wei-Hung; Sankhala, Rajeshwer S.; Hajduczki, Agnes; Martinez, Elizabeth J.; Peterson, Caroline E.; Chang, William C.; Choe, Misook; Smith, Clayton; Lee, Parker J.; Headley, Jarrett A.; Taddese, Mekdi G.; Elyard, Hanne A.; Cook, Anthony; Anderson, Alexander; Wuertz, Kathryn McGuckin; Dong, Ming; Swafford, Isabella; Case, James Brett; Currier, Jeffrey R.; Lal, Kerri G.; Molnar, Sebastian; Nair, Manoj S.; Dussupt, Vincent; Daye, Sharon P.; Zeng, Xiankun; Barkei, Erica K.; Staples, Hilary M.; Alfson, Kendra; Carrion, Ricardo; Krebs, Shelly J.; Paquin-Proulx, Dominic; Karasavva, Nicos; Polonis, Victoria R.; Jagodzinski, Linda L.; Amare, Mihret F.; Vasan, Sandhya; Scott, Paul T.; Huang, Yaoxing; Ho, David D.; de Val, Natalia; Diamond, Michael S.; Lewis, Mark G.; Rao, Mangala; Matyas, Gary R.; Gromowski, Gregory D.; Peel, Sheila A.; Michael, Nelson L.; Bolton, Diane L.; Modjarrad, Kayvon

SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses

NPJ VACCINES

IF6.5

2021-12-1356

OAAI

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

CELL REPORTS

IF6.9

2021-12-01114

OAAI

Joyce, M. Gordon; Chen, Wei-Hung; Sankhala, Rajeshwer S.; Hajduczki, Agnes; Thomas, Paul, V; Choe, Misook; Martinez, Elizabeth J.; Chang, William C.; Peterson, Caroline E.; Morrison, Elaine B.; Smith, Clayton; Chen, Rita E.; Ahmed, Aslaa; Wieczorek, Lindsay; Anderson, Alexander; Case, James Brett; Li, Yifan; Oertel, Therese; Rosado, Lorean; Ganesh, Akshaya; Whalen, Connor; Carmen, Joshua M.; Mendez-Rivera, Letzibeth; Karch, Christopher P.; Gohain, Neelakshi; Villar, Zuzana; McCurdy, David; Beck, Zoltan; Kim, Jiae; Shrivastava, Shikha; Jobe, Ousman; Dussupt, Vincent; Molnar, Sebastian; Tran, Ursula; Kannadka, Chandrika B.; Soman, Sandrine; Kuklis, Caitlin; Zemil, Michelle; Khanh, Htet; Wu, Weimin; Cole, Matthew A.; Duso, Debra K.; Kummer, Larry W.; Lang, Tricia J.; Muncil, Shania E.; Currier, Jeffrey R.; Krebs, Shelly J.; Polonis, Victoria R.; Rajan, Saravanan; McTamney, Patrick M.; Esser, Mark T.; Reiley, William W.; Rolland, Morgane; de Val, Natalia; Diamond, Michael S.; Gromowski, Gregory D.; Matyas, Gary R.; Rao, Mangala; Michael, Nelson L.; Modjarrad, Kayvon

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

NATURE IMMUNOLOGY

IF27.6

2021-10-2942

OAAI

Dussupt, Vincent; Sankhala, Rajeshwer S.; Mendez-Rivera, Letzibeth; Townsley, Samantha M.; Schmidt, Fabian; Wieczorek, Lindsay; Lal, Kerri G.; Donofrio, Gina C.; Tran, Ursula; Jackson, Nathaniel D.; Zaky, Weam, I; Zemil, Michelle; Tritsch, Sarah R.; Chen, Wei-Hung; Martinez, Elizabeth J.; Ahmed, Aslaa; Choe, Misook; Chang, William C.; Hajduczki, Agnes; Jian, Ningbo; Peterson, Caroline E.; Rees, Phyllis A.; Rutkowska, Magdalena; Slike, Bonnie M.; Selverian, Christopher N.; Swafford, Isabella; Teng, I-Ting; Thomas, Paul, V; Zhou, Tongqing; Smith, Clayton J.; Currier, Jeffrey R.; Kwong, Peter D.; Rolland, Morgane; Davidson, Edgar; Doranz, Benjamin J.; Mores, Christopher N.; Hatziioannou, Theodora; Reiley, William W.; Bieniasz, Paul D.; Paquin-Proulx, Dominic; Gromowski, Gregory D.; Polonis, Victoria R.; Michael, Nelson L.; Modjarrad, Kayvon; Joyce, M. Gordon; Krebs, Shelly J.

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-09-0143

OAAI

King, Hannah A. D.; Joyce, M. Gordon; Naouar, Ines Elakhal; Ahmed, Aslaa; Cincotta, Camila Macedo; Subra, Caroline; Peachman, Kristina K.; Hack, Holly H.; Chen, Rita E.; Thomas, Paul, V; Chen, Wei-Hung; Sankhala, Rajeshwer S.; Hajduczki, Agnes; Martinez, Elizabeth J.; Peterson, Caroline E.; Chang, William C.; Choe, Misook; Smith, Clayton; Headley, Jarrett A.; Elyard, Hanne A.; Cook, Anthony; Anderson, Alexander; Wuertz, Kathryn McGuckin; Dong, Ming; Swafford, Isabella; Case, James B.; Currier, Jeffrey R.; Lal, Kerri G.; Amare, Mihret F.; Dussupt, Vincent; Molnar, Sebastian; Daye, Sharon P.; Zeng, Xiankun; Barkei, Erica K.; Alfson, Kendra; Staples, Hilary M.; Carrion, Ricardo; Krebs, Shelly J.; Paquin-Proulx, Dominic; Karasavvas, Nicos; Polonis, Victoria R.; Jagodzinski, Linda L.; Vasan, Sandhya; Scott, Paul T.; Huang, Yaoxing; Nair, Manoj S.; Ho, David D.; de Val, Natalia; Diamond, Michael S.; Lewis, Mark G.; Rao, Mangala; Matyas, Gary R.; Gromowski, Gregory D.; Peel, Sheila A.; Michael, Nelson L.; Modjarrad, Kayvon; Bolton, Diane L.

Fluorescence artifact correction in the thrombin generation assay: Necessity for correction algorithms in procoagulant samples

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2021-03-013

OAAI

Modified aptamers as reagents to characterize recombinant human erythropoietin products

SCIENTIFIC REPORTS

IF3.9

2020-10-298

OAAI

Comparative Analysis of Thrombin Calibration Algorithms and Correction for Thrombin-α2macroglobulin Activity

JOURNAL OF CLINICAL MEDICINE