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Tumor necrosis factor receptor 2 activation elicits sex-specific effects on cortical myelin proteins and functional recovery in a model of multiple sclerosis Nguyen, Kayla L.; Bhatt, Ishaan J.; Gupta, Shruti; Showkat, Nazaf; Swanson, Kathryn A.; Fischer, Roman; Kontermann, Roland E.; Pfizenmaier, Klaus; Bracchi-Ricard, Valerie; Bethea, John R. 分享 收藏
The TNFR1 antagonist Atrosimab reduces neuronal loss, glial activation and memory deficits in an acute mouse model of neurodegeneration TNFR1拮抗剂Atrosimab可减少急性神经变性小鼠模型中的神经元丢失，神经胶质激活和记忆缺陷 Orti-Casan, Natalia; Boerema, Ate S. S.; Kopke, Karina; Ebskamp, Amber; Keijser, Jan; Zhang, Yuequ; Chen, Tingting; Dolga, Amalia M. M.; Broersen, Kerensa; Fischer, Roman; Pfizenmaier, Klaus; Kontermann, Roland E. E.; Eisel, Ulrich L. M. 分享 收藏
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS Pegoretti, Valentina; Bauer, Jan; Fischer, Roman; Paro, Iskra; Douwenga, Wanda; Kontermann, Roland E.; Pfizenmaier, Klaus; Houben, Evelien; Broux, Bieke; Hellings, Niels; Baron, Wia; Laman, Jon D.; Eisel, Ulrich L. M. 分享 收藏
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Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF 胸腺内树突状细胞偏向性前体通过IRF8-driven跨膜TNF促进人T细胞谱系的规范 Liang, Kai Ling; Roels, Juliette; Lavaert, Marieke; Putteman, Tom; Boehme, Lena; Tilleman, Laurentijn; Velghe, Imke; Pegoretti, Valentina; van de Walle, Inge; Sontag, Stephanie; Vandewalle, Jolien; Vandekerckhove, Bart; Leclercq, Georges; Van Vlierberghe, Pieter; Libert, Claude; Van Nieuwerburgh, Filip; Fischer, Roman; Kontermann, Roland E.; Pfizenmaier, Klaus; Doody, Gina; Zenke, Martin; Taghon, Tom 分享 收藏
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The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation TNFR1拮抗剂Atrosimab在小鼠急性和慢性炎症模型中具有治疗作用 Richter, Fabian; Williams, Sarah K.; John, Katharina; Huber, Carina; Vaslin, Camille; Zanker, Henri; Fairless, Richard; Pichi, Kira; Marhenke, Silke; Vogel, Arndt; Dhaen, Marie-Ann; Herrmann, Stefanie; Herrmann, Andreas; Pfizenmaier, Klaus; Bantel, Heike; Diem, Ricarda; Kontermann, Roland E.; Fischer, Roman 分享 收藏
TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice TNF-Receptor-1抑制减少NAFLD小鼠的肝脂肪变性，肝细胞损伤和纤维化 Wandrer, Franziska; Liebig, Stephanie; Marhenke, Silke; Vogel, Arndt; John, Katharina; Manns, Michael P.; Teufel, Andreas; Itzel, Timo; Longerich, Thomas; Maier, Olaf; Fischer, Roman; Kontermann, Roland E.; Pfizenmaier, Klaus; Schulze-Osthoff, Klaus; Bantel, Heike 分享 收藏
Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis Fischer, Roman; Padutsch, Tanja; Bracchi-Ricard, Valerie; Murphy, Kayla L.; Martinez, George. F.; Delguercio, Niky; Elmer, Nicholas; Sendetski, Maksim; Diem, Ricarda; Eisel, Ulrich L. M.; Smeyne, Richard J.; Kontermann, Roland E.; Pfizenmaier, Klaus; Bethea, John R. 分享 收藏
TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes TNFR2促进Treg介导的跨性别神经性疼痛恢复 Fischer, Roman; Sendetski, Maksim; del Rivero, Tania; Martinez, George F.; Bracchi-Ricard, Valerie; Swanson, Kathryn A.; Pruzinsky, Elizabeth K.; Delguercio, Niky; Rosalino, Michael J.; Padutsch, Tanja; Kontermann, Roland E.; Pfizenmaier, Klaus; Bethea, John R. 分享 收藏
Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury Gerald, Marcus J.; Bracchi-Ricard, Valerie; Ricard, Jerome; Fischer, Roman; Nandakumar, Bharadwaj; Blumenthal, Gary H.; Williams, Raushaun; Kontermann, Roland E.; Pfizenmaier, Klaus; Moxon, Karen A.; Bethea, John R. 分享 收藏
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Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis Williams, Sarah K.; Fairless, Richard; Maier, Olaf; Liermann, Patricia C.; Pichi, Kira; Fischer, Roman; Eisel, Ulrich L. M.; Kontermann, Roland; Herrmann, Andreas; Weksler, Babette; Romero, Nacho; Couraud, Pierre-Olivier; Pfizenmaier, Klaus; Diem, Ricarda 分享 收藏
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Selective Activation of Tumor Necrosis Factor Receptor II Induces Antiinflammatory Responses and Alleviates Experimental Arthritis Fischer, Roman; Proske, Marcel; Duffey, Maelle; Stangl, Hubert; Martinez, George F.; Peters, Nathalie; Kraske, Alexandra; Straub, Rainer H.; Bethea, John R.; Kontermann, Roland E.; Pfizenmaier, Klaus 分享 收藏
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