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Recommendations for Studying In Situ Extracellular Vesicles From Solid Tissue 关于从实体组织中研究原位细胞外囊泡的建议 Crescitelli, Rossella; Huang, Yiyao; Hendrix, An; Hill, Andrew F.; Hurwitz, Stephanie N.; Ikezu, Tsuneya; Levy, Efrat; Puig, Berta; Paolini, Lucia; Vella, Laura J. 分享 收藏
Amyloid precursor protein and presenilin-1 knock-in immunodeficient mice exhibit intraneuronal Aβ pathology, microgliosis, and extensive neuronal loss 淀粉样前体蛋白和早老蛋白-1基因敲入免疫缺陷小鼠表现出神经元内Aβ病变、小胶质细胞增生和广泛的神经元丢失。 Yeapuri, P; Machhi, J; Foster, EG; Kadry, R; Bhattarai, S; Lu, YM; Sil, S; Sapkota, R; Srivastava, S; Kumar, M; Ikezu, T; Poluektova, LY; Gendelman, HE; Mosley, RL 分享 收藏
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Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs Jin, Yunjung; Li, Fuyao; Li, Zonghua; Ikezu, Tadafumi C.; O'Leary, Justin; Selvaraj, Manikandan; Zhu, Yiyang; Martens, Yuka A.; Koga, Shunsuke; Santhakumar, Hannah; Li, Yonghe; Lu, Wenyan; You, Yang; Lolo, Kiara; Deture, Michael; Beasley, Alexandra I.; Davis, Mary D.; Mclean, Pamela J.; Ross, Owen A.; Kanekiyo, Takahisa; Ikezu, Tsuneya; Caulfield, Thomas; Carr, Jonathan; Wszolek, Zbigniew K.; Bu, Guojun; Dickson, Dennis W.; Zhao, Na 分享 收藏
Single-extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron-derived EVs 单胞外囊泡 (EV) 分析验证了L1细胞粘附分子 (L1CAM) 作为神经元源性EV的可靠生物标志物的使用 Nogueras-Ortiz, Carlos J.; Eren, Erden; Yao, Pamela; Calzada, Elizabeth; Dunn, Christopher; Volpert, Olga; Delgado-Peraza, Francheska; Mustapic, Maja; Lyashkov, Alexey; Rubio, F. Javier; Vreones, Michael; Cheng, Lesley; You, Yang; Hill, Andrew F.; Ikezu, Tsuneya; Eitan, Erez; Goetzl, Edward J.; Kapogiannis, Dimitrios 分享 收藏
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Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies Sandau, Ursula S.; Magana, Setty M.; Costa, Julia; Nolan, John P.; Ikezu, Tsuneya; Vella, Laura J.; Jackson, Hannah K.; Moreira, Lissette Retana; Palacio, Paola Loreto; Hill, Andrew F.; Quinn, Joseph F.; Van Keuren-Jensen, Kendall R.; Mcfarland, Trevor J.; Palade, Joanna; Sribnick, Eric A.; Su, Huaqi; Vekrellis, Kostas; Coyle, Beth; Yang, You; Falcon-Perez, Juan M.; Nieuwland, Rienk; Saugstad, Julie A. 分享 收藏
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APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints Yin, Zhuoran; Rosenzweig, Neta; Kleemann, Kilian L.; Zhang, Xiaoming; Brandao, Wesley; Margeta, Milica A.; Schroeder, Caitlin; Sivanathan, Kisha N.; Silveira, Sebastian; Gauthier, Christian; Mallah, Dania; Pitts, Kristen M.; Durao, Ana; Herron, Shawn; Shorey, Hannah; Cheng, Yiran; Barry, Jen-Li; Krishnan, Rajesh K.; Wakelin, Sam; Rhee, Jared; Yung, Anthony; Aronchik, Michael; Wang, Chao; Jain, Nimansha; Bao, Xin; Gerrits, Emma; Brouwer, Nieske; Deik, Amy; Tenen, Daniel G.; Ikezu, Tsuneya; Santander, Nicolas G.; Mckinsey, Gabriel L.; Baufeld, Caroline; Sheppard, Dean; Krasemann, Susanne; Nowarski, Roni; Eggen, Bart J. L.; Clish, Clary; Tanzi, Rudolph E.; Madore, Charlotte; Arnold, Thomas D.; Holtzman, David M.; Butovsky, Oleg 分享 收藏
ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids You, Yang; Zhang, Zhengrong; Sultana, Nadia; Ericsson, Maria; Martens, Yuka A.; Sun, Min; Kanekiyo, Takahisa; Ikezu, Seiko; Shaffer, Scott A.; Ikezu, Tsuneya 分享 收藏
Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications Zhang, Zhengrong; Yu, Kaiwen; You, Yang; Jiang, Peizhou; Wu, Zhiping; DeTure, Michael A. A.; Dickson, Dennis W. W.; Ikezu, Seiko; Peng, Junmin; Ikezu, Tsuneya 分享 收藏
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Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia 调节小胶质细胞miR-155转录表型通过限制Clec7a/Galectin-3神经退行性小胶质细胞来缓解阿尔茨海默氏症诱导的视网膜血管病变 Shi, Haoshen; Yin, Zhuoran; Koronyo, Yosef; Fuchs, Dieu-Trang; Sheyn, Julia; Davis, Miyah R.; Wilson, Jered W.; Margeta, Milica A.; Pitts, Kristen M.; Herron, Shawn; Ikezu, Seiko; Ikezu, Tsuneya; Graham, Stuart L.; Gupta, Vivek K.; Black, Keith L.; Mirzaei, Mehdi; Butovsky, Oleg; Koronyo-Hamaoui, Maya 分享 收藏
Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress (Jun, 10.1007/s12192-022-01279-9, 2022) Okusha, Yuka; Lang, Benjamin J.; Murshid, Ayesha; Borges, Thiago J.; Holton, Kristina M.; Clark-Matott, Joanne; Doshi, Sachin; Ikezu, Tsuneya; Calderwood, Stuart K. 分享 收藏
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Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells You, Yang; Hersh, Samuel W.; Aslebagh, Roshanak; Shaffer, Scott A.; Ikezu, Seiko; Mez, Jesse; Lunetta, Kathryn L.; Logue, Mark W.; Farrer, Lindsay A.; Ikezu, Tsuneya 分享 收藏
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