Herman S. Overkleeft - Publications, H-index & Citations

Herman S. Overkleeft

leiden university

83H指数

926论文数

2.9W被引数

收录论文 383

发表时间

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl-Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies 解析A4GALT机制及其通过金刚烷基-半乳糖基神经酰胺类似物的调控：推进法布里病治疗策略

Angewandte Chemie-International Edition

IF16.9

2026-08-28

OAAI

Nicky de Koster; Òscar Vidal-Gironès; Rowan de Graaf; Ken Kok; Lindsey T. Lelieveld; Jackelien Hoogervorst; Maria J. Ferraz; José Pablo Rivas-Fernández; Rob F. Lammers; Herman S. Overkleeft; Johannes M. F. G. Aerts; Rolf G. Boot; Carme Rovira; Marta Artola

Fully protected pyrophosphates via phosphorobromidates for the synthesis of biopolymers 通过溴代膦酸酯制备的完全保护的焦磷酸盐用于生物聚合物的合成

chem. sci.

IF0

2026-04-16

OAAI

Sven Wijngaarden; Femke L. A. M. van der Heijden; Koen J. Rijpkema; Bob van Puffelen; Nico J. Meeuwenoord; Danicia Ramcharan; Gijsbert A. van der Marel; Jeroen D. C. Codée; Herman S. Overkleeft; Dmitri V. Filippov

A Practical and Flexible De Novo Synthesis of Deoxygenated Carbasugars and Their Cyclitol Epoxides 一种实用且灵活的去氧卡巴糖及其环己itol环氧化物的从头合成

European Journal of Organic Chemistry

IF2.7

2026-04-13

OAAI

Yevhenii Radchenko; Nick D. F. Puijmbroeck; Sanne M. Verduin; Jeroen D. C. Codée; Herman S. Overkleeft

Carfilzomib-specific proteasome β5/β2 inhibition drives cardiotoxicity via remodeling of protein homeostasis and the renin-angiotensin-system 卡非佐米特异性蛋白酶体β5/β2抑制通过重塑蛋白质稳态和肾素-血管紧张素系统驱动心脏毒性。

iScience

IF4.1

2025-07-29

OAAI

Max Mendez-Lopez; Andrej Besse; Christian Zuppinger; Christian Perez-Shibayama; Cristina Gil-Cruz; Bogdan I. Florea; Angelina De Martin; Mechthild Lütge; Deborah Beckerova; Simon Klimovic; Xiang Zhou; Leo Rasche; Jan Pribyl; Vladimir Rotrekl; Burkhard Ludewig; Herman S. Overkleeft; Lenka Besse; Christoph Driessen

LIMP-2 deficiency-associated glycolipid abnormalities in mice LIMP-2缺乏相关的糖脂异常在小鼠中

biochimica et biophysica acta molecular and cell biology of lipids

IF0

2025-07-08

OAAI

Paulo Gaspar; André R.A. Marques; Maria J. Ferraz; Markus Damme; Gertjan Kramer; Mina Mirzaian; Marion Gijbels; Roelof Ottenhoff; Cindy van Roomen; Herman S. Overkleeft; Michael Schwake; Saskia Heybrock; Maria Carmo Macário; Paul Saftig; Johannes M. Aerts

Synthesis of a Set of Staphylococcus Aureus Capsular Polysaccharide Type 1 Oligosaccharides Carrying Taurine Esters

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2025-03-01

PREAI

Osterlid, Kitt Emilie; Cergano, Renata; Overkleeft, Herman S.; van der Marel, Gijsbert A.; Codee, Jeroen D. C.

Activity-Based Protein Profiling Identifies an α-Amylase Family Protein Contributing to the Virulence of Methicillin-Resistant Staphylococcus aureus

ACS INFECTIOUS DISEASES

IF3.8

2025-02-06

PREAI

Uddin, Md Jalal; Julin, Kjersti; Overkleeft, Herman S.; Johannessen, Mona; Lentz, Christian S.

Precision Activity-Based α-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-12-27

PREAI

Pickles, Isabelle B.; Chen, Yurong; Moroz, Olga; Brown, Haley A.; de Boer, Casper; Armstrong, Zachary; Mcgregor, Nicholas G. S.; Artola, Marta; Codee, Jeroen D. C.; Koropatkin, Nicole M.; Overkleeft, Herman S.; Davies, Gideon J.

Synthesis and Biological Evaluation of Deoxycyclophellitols as Human Retaining β-Glucosidase Inhibitors

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2024-11-03

OAAI

Radchenko, Yevhenii; Su, Qin; Schroder, Sybrin S.; van Gijlswijk, Luke; Artola, Marta; Aerts, Johannes M. F. G.; Codee, Jeroen D. C.; Overkleeft, Herman S.

substrates for GBA1 in the discovery of glycosylated sterols

JOURNAL OF LIPID RESEARCH

IF4.1

2024-11-01

PREAI

Bannink, Stef; Bila, Kateryna O.; van Weperen, Joosje; Ligthart, Nina A. M.; Ferraz, Maria J.; Boot, Rolf G.; van der Vliet, Daan; Boer, Daphne. E. C.; Overkleeft, Herman S.; Artola, Marta; Aerts, Johannes M. F. G.

From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-08-30

OAAI

Artola, Marta; Aerts, Johannes M. F. G.; van der Marel, Gijsbert A.; Rovira, Carme; Codee, Jeroen D. C.; Davies, Gideon J.; Overkleeft, Herman S.

A PIKfyve modulator combined with an integrated stress response inhibitor to treat lysosomal storage diseases 一种PIKfyve调节剂与应激反应抑制剂联用治疗溶酶体贮积症

Proceedings of the National Academy of Sciences

IF9.1

2024-08-16

OAAI

William C. Hou; Lynée A. Massey; Derek Rhoades; Yin Wu; Wen Ren; Chiara Frank; Herman S. Overkleeft; Jeffrey W. Kelly

Novel N,N-Dimethyl-idarubicin Analogues Are Effective Cytotoxic Agents for ABCB1-Overexpressing, Doxorubicin-Resistant Cells

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-08-01

OAAI

van Gelder, Merle A.; Li, Yufeng; Wander, Dennis P. A.; Berlin, Ilana; Overkleeft, Hermen S.; van der Zanden, Sabina Y.; Neefjes, Jacques J. C.

Epi-Cyclophellitol Cyclosulfate, a Mechanism-Based Endoplasmic Reticulum α-Glucosidase II Inhibitor, Blocks Replication of SARS-CoV-2 and Other Coronaviruses

ACS CENTRAL SCIENCE

IF10.4

2024-07-25

OAAI

Thaler, Melissa; Ofman, Tim P.; Kok, Ken; Heming, Jurriaan J. A.; Moran, Elisha; Pickles, Isabelle; Leijs, Anouk A.; van den Nieuwendijk, Adrianus M. C. H.; van den Berg, Richard J. B. H. N.; Ruijgrok, Gijs; Armstrong, Zachary; Salgado-Benvindo, Clarisse; Ninaber, Dennis K.; Snijder, Eric J.; van Boeckel, Constant A. A.; Artola, Marta; Davies, Gideon J.; Overkleeft, Herman S.; van Hemert, Martijn J.

Parascedosporium putredinis NO1 tailors its secretome for different lignocellulosic substrates

MICROBIOLOGY SPECTRUM

IF3.8

2024-07-02

OAAI

Scott, Conor J. R.; Mcgregor, Nicholas G. S.; Leadbeater, Daniel R.; Oates, Nicola C.; Hossbach, Janina; Abood, Amira; Setchfield, Alexander; Dowle, Adam; Overkleeft, Herman S.; Davies, Gideon J.; Bruce, Neil C.

Detection of Sulfoquinovosidase Activity in Cell Lysates Using Activity-Based Probes

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-05-21

OAAI

Li, Zirui; Pickles, Isabelle B.; Sharma, Mahima; Melling, Benjamin; Pallasdies, Luise; Codee, Jeroen D. C.; Williams, Spencer J.; Overkleeft, Herman S.; Davies, Gideon J.

Conformational and Electronic Variations in 1,2-and 1,5a-Cyclophellitols and their Impact on Retaining α-Glucosidase Inhibition

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2024-04-24

OAAI

Ofman, Tim P.; Heming, Jurriaan J. A.; Nin-Hill, Alba; Kuellmer, Florian; Moran, Elisha; Bennett, Megan; Steneker, Roy; Klein, Anne-Mei; Ruijgrok, Gijs; Kok, Ken; Armstrong, Zach W. B.; Aerts, Johannes M. F. G.; van Der Marel, Gijsbert A.; Rovira, Carme; Davies, Gideon J.; Artola, Marta; Codee, Jeroen D. C.; Overkleeft, Herman S.

Synthesis and application of bacterial exopolysaccharides

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2024-02-01

OAAI

Ruijgrok, Gijs; Wu, Dung-Yeh; Overkleeft, Herman S.; Codee, Jeroen D. C.

Selective labelling of GBA2 in cells with fluorescent β-d-arabinofuranosyl cyclitol aziridines

CHEMICAL SCIENCE

IF7.4

2024-01-01

OAAI

Su, Qin; Louwerse, Max; Lammers, Rob F.; Maurits, Elmer; Janssen, Max; Boot, Rolf G.; Borlandelli, Valentina; Offen, Wendy A.; Linzel, Daniel; Schroder, Sybrin P.; Davies, Gideon J.; Overkleeft, Herman S.; Artola, Marta; Aerts, Johannes M. F. G.

Structure-guided design of C3-branched swainsonine as potent and selective human Golgi α-mannosidase (GMII) inhibitor

CHEMICAL COMMUNICATIONS

IF4.2

2024-01-01

PREAI

Koemans, Tony; Bennett, Megan; Ferraz, Maria J.; Armstrong, Zachary; Artola, Marta; Aerts, Johannes M. F. G.; Codee, Jeroen D. C.; Overkleeft, Herman S.; Davies, Gideon J.

研究方向