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J

Juan Dubrot

broad institute of mit and harvard
H指数:31
被引数:4,081

个人简介

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教育背景

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工作经历

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荣誉奖项

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Inflammatory cytokines induce new cancer dependencies

炎性细胞因子诱导新的癌症依赖性

Nature Genetics
IF29
2026-06-090
PRE
Collins K. Cheruiyot; Sarah Y. Kim; Juan Dubrot; Sarah K. Lane-Reticker; Alex Miranda; Ashwin V. Kammula; Jonathan J. Perera; Peter P. Du; Cun Lan Chuong; Rachel A. Fetterman; Nelson H. Knudsen; Aiping Jiang; Juliette S. M. T. Suermondt; Lomax F. Pass; Cong Fu; Meng-Ju Wu; Lei Shi; Seth Anderson; Audrey J. Muscato; Omar I. Avila; Ian C. Kohnle; Emily A. Kessler; Hans W. Pope; Sarah G. Noel; Kira E. Olander; Jooho Chung; Kayla J. Colvin; Nabeel Bardeesy; Kathleen B. Yates; Robert T. Manguso
In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target

体内CRISPR筛选在头颈癌中揭示Uchl5作为免疫治疗靶点

Nature Communications
IF15.7
2025-09-290
OAAI
Cong Fu; Robert Saddawi-Konefka; Jordan M. Chinai; Sarah Y. Kim; Ashwin V. Kammula; Jonathan J. Perera; Aiping Jiang; Payal Tiwari; Erin N. Kistler; Shiqi Tang; Sarah M. Luna; Kayla J. Colvin; Juan Dubrot; Seth Anderson; Rachel A. Fetterman; Cun Lan Chuong; Sarah K. Lane-Reticker; Collins K. Cheruiyot; Audrey J. Muscato; Zahra Alipour; Douglas R. Adkins; Gabriel K. Griffin; Bradley E. Bernstein; Ann Marie Egloff; Kathleen B. Yates; Rebecca D. Chernock; J. Silvio Gutkind; Ravindra Uppaluri; Robert T. Manguso
Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications

利用胰腺导管腺癌的表观遗传改变进行临床应用

SEMINARS IN CANCER BIOLOGY
IF15.7
2025-02-010
OAAI
Tost, Jorg; Ak-Aksoy, Secil; Campa, Daniele; Corradi, Chiara; Farinella, Riccardo; Ibanez-Costa, Alejandro; Dubrot, Juan; Earl, Julie; Melian, Emma Barreto; Kataki, Agapi; Kolnikova, Georgina; Madjarov, Gjorgji; Chaushevska, Marija; Strnadel, Jan; Tanic, Miljana; Tomas, Miroslav; Dubovan, Peter; Urbanova, Maria; Buocikova, Verona; Smolkova, Bozena
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening

通过迭代体内全基因组CRISPR筛选揭示白血病-car-t反应的内在决定因素

NATURE COMMUNICATIONS
IF15.7
2023-12-054
OAAI
Ramos, Azucena; Koch, Catherine E.; Liu-Lupo, Yunpeng; Hellinger, Riley D.; Kyung, Taeyoon; Abbott, Keene L.; Frose, Julia; Goulet, Daniel; Gordon, Khloe S.; Eidell, Keith P.; Leclerc, Paul; Whittaker, Charles A.; Larson, Rebecca C.; Muscato, Audrey J.; Yates, Kathleen B.; Dubrot, Juan; Doench, John G.; Regev, Aviv; Vander Heiden, Matthew G.; Maus, Marcela V.; Manguso, Robert T.; Birnbaum, Michael E.; Hemann, Michael T.
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

体内CRISPR筛选揭示了癌症免疫逃避途径的景观

NATURE IMMUNOLOGY
IF27.6
2022-09-2382
PRE
Dubrot, Juan; Du, Peter P.; Lane-Reticker, Sarah Kate; Kessler, Emily A.; Muscato, Audrey J.; Mehta, Arnav; Freeman, Samuel S.; Allen, Peter M.; Olander, Kira E.; Ockerman, Kyle M.; Wolfe, Clara H.; Wiesmann, Fabius; Knudsen, Nelson H.; Tsao, Hsiao-Wei; Iracheta-Vellve, Arvin; Schneider, Emily M.; Rivera-Rosario, Andrea N.; Kohnle, Ian C.; Pope, Hans W.; Ayer, Austin; Mishra, Gargi; Zimmer, Margaret D.; Kim, Sarah Y.; Mahapatra, Animesh; Ebrahimi-Nik, Hakimeh; Frederick, Dennie T.; Boland, Genevieve M.; Haining, W. Nicholas; Root, David E.; Doench, John G.; Hacohen, Nir; Yates, Kathleen B.; Manguso, Robert T.
Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma
CANCER DISCOVERY
IF33.3
2022-03-0878
OA
Wu, Meng-Ju; Shi, Lei; Dubrot, Juan; Merritt, Joshua; Vijay, Vindhya; Wei, Ting-Yu; Kessler, Emily; Olander, Kira E.; Adil, Ramzi; Pankaj, Amaya; Tummala, Krishna Seshu; Weeresekara, Vajira; Zhen, Yuanli; Wu, Qibiao; Luo, Meiqi; Shen, William; Garcia-Beccaria, Maria; Fernandez-Vaquero, Mirian; Hudson, Christine; Ronseaux, Sebastien; Sun, Yi; Saad-Berreta, Rodrigo; Jenkins, Russell W.; Wang, Tong; Heikenwalder, Mathias; Ferrone, Cristina R.; Goyal, Lipika; Nicolay, Brandon; Deshpande, Vikram; Kohli, Rahul M.; Zheng, Hongwu; Manguso, Robert T.; Bardeesy, Nabeel
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma
IMMUNITY
IF26.3
2021-03-0156
OAAI
Dubrot, Juan; Lane-Reticker, Sarah Kate; Kessler, Emily A.; Ayer, Austin; Mishra, Gargi; Wolfe, Clara H.; Zimmer, Margaret D.; Du, Peter P.; Mahapatra, Animesh; Ockerman, Kyle M.; Davis, Thomas G. R.; Kohnle, Ian C.; Pope, Hans W.; Allen, Peter M.; Olander, Kira E.; Iracheta-Vellve, Arvin; Doench, John G.; Haining, W. Nicholas; Yates, Kathleen B.; Manguso, Robert T.
The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

Ly6Chi单核细胞的异质性控制其分化为iNOS巨噬细胞或单核细胞衍生的树突状细胞

IMMUNITY
IF26.3
2016-12-01242
OAAI
Menezes, Shinelle; Melandri, Daisy; Anselmi, Giorgio; Perchet, Thibaut; Loschko, Jakob; Dubrot, Juan; Patel, Rajen; Gautier, Emmanuel L.; Hugues, Stephanie; Longhi, M. Paula; Henry, Jake Y.; Quezada, Sergio A.; Lauvau, Gregoire; Lennon-Dumenil, Ana-Maria; Gutierrez-Martinez, Enrique; Bessis, Alain; Gomez-Perdiguero, Elisa; Jacome-Galarza, Christian E.; Garner, Hannah; Geissmann, Frederic; Golub, Rachel; Nussenzweig, Michel C.; Guermonprez, Pierre

研究方向

暂未获取到该数据
I
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S
Sandra Hervás‐Stubbs
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A
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C
Carlos Alfaro
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S
Stéphanie Hugues
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J
José Luis Perez‐Gracia
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O
Oihana Murillo
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R
Robert T. Manguso
H 指数:23论文数:105被引数:6,936
D
Dale Brighouse
H 指数:10论文数:25被引数:652
I
Iván Martínez‐Forero
H 指数:22论文数:97被引数:2,044