Matthew G. Holt - Publications, H-index & Citations

Matthew G. Holt

University of Porto

41H指数

107论文数

1.1W被引数

收录论文 51

发表时间

Frozen in Place: Proximity Labeling Maps Glial Interactomes Across Cell States 冷冻固定：邻近标记技术绘制不同细胞状态下的胶质细胞互作组图谱

Glia

IF5.1

2026-08-30

OAAI

João Baltar; Rebecca Abati; Luísa Florido; Matthew G. Holt

Written in the Stars: Astrocyte Biology From Evolution to Disease 写在星空中：从进化到疾病中的星形胶质细胞生物学

Acta Physiologica

IF5.6

2026-08-28

PREAI

Carmen Falcone; Lutgarde Arckens; Monica Baiula; Andrea Bedini; Riccardo Bocchi; Matthew J. Broadhead; Marco Caprini; Fabio Cavaliere; Fabrizia Cesca; Helena H. Chowdhury; Katarzyna Ciuba; Laura Civiero; Carole Escartin; Stefano Ferroni; Francesco Formaggio; Angelisa Frasca; Rossella Gratton; Matthew Holt; Nunzio Iraci; Marko Kreft; Loredana Leggio; Annamaria Lia; Anna R. Malik; Rogier Min; Franziska E. Müller; Cahuê Murat; Maria João Pereira; Aleksandra Pekowska; Francesco Petrelli; Paula Ramos-Gonzalez; Maria V. Sanchez-Mico; Zala Smole; Dimitra Sokolova; Maite Solas; Alessia Soldano; Lukasz Mateusz Szewczyk; Carola Torazza; Francesco Paolo Ulloa Severino; Nerea Urrestizala-Arenaza; Andre Zeug; Jiafeng Zhou; Micaela Zonta; Robert Zorec; Alexei Verkhratsky; Nilhan Gunhanlar

ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis ATP13A4调控细胞外多胺水平以控制兴奋性突触发生

Nature Communications

IF15.7

2026-08-04

OAAI

Sarah van Veen; Emily Meeus; Dolores Irala; Kristina Sakers; Zhaolin Liu; Justin Savage; Gabrielle Séjourné; Dhanesh Sivadasan Bindu; Elke Ausloos; Hanna Elzbieta Grzesik; Hanne Dhondt; Nina Schoonvliet; Chris Van den Haute; Joris Van Asselberghs; Marta Montpeyó Garcia-Moreno; Keimpe Wierda; Veerle Baekelandt; Konrad Platzer; Kevin Rostasy; Kai Lee Yap; Jan Eggermont; Matthew G. Holt; Cagla Eroglu; Peter Vangheluwe

Multi-Network Co-expression Analysis Enhances Biological Insights from Single-Cell Gene Expression 多网络共表达分析增强了单细胞基因表达中的生物学洞见

interdisciplinary sciences: computational life sciences

IF0

2026-02-06

OAAI

Alicia Gómez-Pascual; Araks Martirosyan; Katja Hebestreit; Andrew Kottick; Michelle Mighdoll; Victor Hanson-Smith; José Luis Mellina-Andreu; Alejandro Cisterna; Matthew G. Holt; Grant Belgard; Sebastian Guelfi; Juan A. Botía

Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity 定向破坏IL2的聚集和受体结合位点，产生具有增强特异性和改进生产能力的设计生物制剂。

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

IF4.1

2025-01-01

OAAI

Dashwood, Amy; Makuyana, Ntombizodwa; van der Kant, Rob; Ghodsinia, Arman; Hernandez, Alvaro R.; Lienart, Stephanie; Burton, Oliver; Dooley, James; Ali, Magda; Kouser, Lubna; Naranjo, Francisco; Holt, Matthew G.; Rousseau, Frederic; Schymkowitz, Joost; Liston, Adrian

Association of Serum Biomarkers With Neurocognitive Decline After PCI in Small Cell Lung Cancer: An Exploratory Study of the Phase III NCT01780675 Trial

CLINICAL LUNG CANCER

IF3.3

2024-11-01

PREAI

Zeng, Haiyan; Hendriks, Lizza E. L.; Belderbos, Jose; Brandts, Lloyd; Compter, Inge; Dubois, Ludwig; Holt, Matthew G.; Houben, Ruud; Schagen, Sanne; Zhang, Xin; Prezzemolo, Teresa; De Ruysscher, Dirk

The astrocyte α1A-adrenoreceptor is a key component of the neuromodulatory system in mouse visual cortex

GLIA

IF5.1

2024-07-12

OAAI

Wahis, Jerome; Akkaya, Cansu; Kirunda, Andre M.; Mak, Aline; Zeise, Karen; Verhaert, Jens; Gasparyan, Hayk; Hovhannisyan, Sargis; Holt, Matthew G.

Regulatory T cells as a possible new target in epilepsy?

EPILEPSIA

IF6.6

2024-06-18

PREAI

Hendrix, Evelien; Vande Vyver, Maxime; Holt, Matthew; Smolders, Ilse

Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice

NATURE COMMUNICATIONS

IF15.7

2024-06-18

OAAI

Bielefeld, P.; Martirosyan, A.; Martin-Suarez, S.; Apresyan, A.; Meerhoff, G. F.; Pestana, F.; Poovathingal, S.; Reijner, N.; Koning, W.; Clement, R. A.; van der Veen, I.; Toledo, E. M.; Polzer, O.; Dura, I.; Hovhannisyan, S.; Nilges, B. S.; Bogdoll, A.; Kashikar, N. D.; Lucassen, P. J.; Belgard, T. G.; Encinas, J. M.; Holt, M. G.; Fitzsimons, C. P.

Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution (vol 19, 7, 2024)

MOLECULAR NEURODEGENERATION

IF17.5

2024-03-25

OAAI

Martirosyan, Araks; Ansari, Rizwan; Pestana, Francisco; Hebestreit, Katja; Gasparyan, Hayk; Aleksanyan, Razmik; Hnatova, Silvia; Poovathingal, Suresh; Marneffe, Catherine; Thal, Dietmar R.; Kottick, Andrew; Hanson-Smith, Victor J.; Guelfi, Sebastian; Plumbly, William; Belgard, T. Grant; Metzakopian, Emmanouil; Holt, Matthew G.

Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution

MOLECULAR NEURODEGENERATION

IF17.5

2024-01-20

OAAI

Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain

EMBO MOLECULAR MEDICINE

IF8.3

2023-03-28

OAAI

Lemaitre, Pierre; Tareen, Samar H. K.; Pasciuto, Emanuela; Mascali, Loriana; Martirosyan, Araks; Callaerts-Vegh, Zsuzsanna; Poovathingal, Suresh; Dooley, James; Holt, Matthew G.; Yshii, Lidia; Liston, Adrian

Astrocyte structural heterogeneity in the mouse hippocampus 小鼠海马的星形胶质细胞结构异质性

GLIA

IF5.1

2023-03-22

OAAI

Viana, Joao Filipe; Machado, Joao Luis; Abreu, Daniela Sofia; Veiga, Alexandra; Barsanti, Sara; Tavares, Gabriela; Martins, Manuella; Sardinha, Vanessa Morais; Guerra-Gomes, Sonia; Domingos, Catia; Pauletti, Alberto; Wahis, Jerome; Liu, Chen; Cali, Corrado; Henneberger, Christian; Holt, Matthew G.; Oliveira, Joao Filipe

Astrocyte heterogeneity and interactions with local neural circuits

ESSAYS IN BIOCHEMISTRY

IF5.7

2023-03-03

OAAI

Holt, Matthew G.

A conformational switch controlling the toxicity of the prion protein

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-08-10

OAAI

Frontzek, Karl; Bardelli, Marco; Senatore, Assunta; Henzi, Anna; Reimann, Regina R.; Bedir, Seden; Marino, Marika; Hussain, Rohanah; Jurt, Simon; Meisl, Georg; Pedotti, Mattia; Mazzola, Federica; Siligardi, Giuliano; Zerbe, Oliver; Losa, Marco; Knowles, Tuomas; Lakkaraju, Asvin; Zhu, Caihong; Schwarz, Petra; Hornemann, Simone; Holt, Matthew G.; Simonelli, Luca; Varani, Luca; Aguzzi, Adriano

Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease 星形胶质细胞钙功能障碍导致阿尔茨海默氏病的早期网络功能亢进

CELL REPORTS

IF6.9

2022-08-01

OAAI

Shah, Disha; Gsell, Willy; Wahis, Jerome; Luckett, Emma S.; Jamoulle, Tarik; Vermaercke, Ben; Preman, Pranav; Moechars, Daan; Hendrickx, Veronique; Jaspers, Tom; Craessaerts, Katleen; Horre, Katrien; Wolfs, Leen; Fiers, Mark; Holt, Matthew; Thal, Dietmar Rudolf; Callaerts-Vegh, Zsuzsanna; D'Hooge, Rudi; Vandenberghe, Rik; Himmelreich, Uwe; Bonin, Vincent; De Strooper, Bart

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation 白细胞介素2的星形胶质细胞靶向基因递送特异性增加脑驻留调节性T细胞数量并防止病理性神经炎症

NATURE IMMUNOLOGY

IF27.6

2022-05-26

OAAI

Yshii, Lidia; Pasciuto, Emanuela; Bielefeld, Pascal; Mascali, Loriana; Lemaitre, Pierre; Marino, Marika; Dooley, James; Kouser, Lubna; Verschoren, Stijn; Lagou, Vasiliki; Kemps, Hannelore; Gervois, Pascal; de Boer, Antina; Burton, Oliver T.; Wahis, Jerome; Verhaert, Jens; Tareen, Samar; Roca, Carlos P.; Singh, Kailash; Whyte, Carly E.; Kerstens, Axelle; Callaerts-Vegh, Zsuzsanna; Poovathingal, Suresh; Prezzemolo, Teresa; Wierda, Keimpe; Dashwood, Amy; Xie, Junhua; Van Wonterghem, Elien; Creemers, Eline; Aloulou, Meryem; Gsell, Willy; Abiega, Oihane; Munck, Sebastian; Vandenbroucke, Roosmarijn E.; Bronckaers, Annelies; Lemmens, Robin; De Strooper, Bart; Van Den Bosch, Ludo; Himmelreich, Uwe; Fitzsimons, Carlos P.; Holt, Matthew G.; Liston, Adrian

Neurophotonic tools for microscopic measurements and manipulation: status report

NEUROPHOTONICS

IF3.8

2022-04-27

OAAI

Abdelfattah, Ahmed S.; Ahuja, Sapna; Akkin, Taner; Allu, Srinivasa Rao; Brake, Joshua; Boas, David A.; Buckley, Erin M.; Campbell, Robert E.; Chen, Anderson, I; Cheng, Xiaojun; Cizmar, Tomas; Costantini, Irene; De Vittorio, Massimo; Devor, Anna; Doran, Patrick R.; El Khatib, Mirna; Emiliani, Valentina; Fomin-Thunemann, Natalie; Fainman, Yeshaiahu; Fernandez-Alfonso, Tomas; Ferri, Christopher G. L.; Gilad, Ariel; Han, Xue; Harris, Andrew; Hillman, Elizabeth M. C.; Hochgeschwender, Ute; Holt, Matthew G.; Ji, Na; Kilic, Kivilcim; Lake, Evelyn M. R.; Li, Lei; Li, Tianqi; Machler, Philipp; Miller, Evan W.; Mesquita, Rickson C.; Nadella, K. M. Naga Srinivas; Nagerl, U. Valentin; Nasu, Yusuke; Nimmerjahn, Axel; Ondrackova, Petra; Pavone, Francesco S.; Campos, Citlali Perez; Peterka, Darcy S.; Pisano, Filippo; Pisanello, Ferruccio; Puppo, Francesca; Sabatini, Bernardo L.; Sadegh, Sanaz; Sakadzic, Sava; Shoham, Shy; Shroff, Sanaya N.; Silver, R. Angus; Sims, Ruth R.; Smith, Spencer L.; Srinivasan, Vivek J.; Thunemann, Martin; Lei Tian; Lin Tian; Troxler, Thomas; Valera, Antoine; Vaziri, Alipasha; Vinogradov, Sergei A.; Vitale, Flavia; Wang, Lihong, V; Uhlirova, Hana; Xu, Chris; Yang, Changhuei; Yang, Mu-Han; Yellen, Gary; Yizhar, Ofer; Zhao, Yongxin

AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model AAV介导的anti-BACE1 VHH递送减轻阿尔茨海默病模型的病理

EMBO MOLECULAR MEDICINE

IF8.3

2022-03-30

OAAI

Marino, Marika; Zhou, Lujia; Rincon, Melvin Y.; Callaerts-Vegh, Zsuzsanna; Verhaert, Jens; Wahis, Jerome; Creemers, Eline; Yshii, Lidia; Wierda, Keimpe; Saito, Takashi; Marneffe, Catherine; Voytyuk, Iryna; Wouters, Yessica; Dewilde, Maarten; Duque, Sandra, I; Vincke, Cecile; Levites, Yona; Golde, Todd E.; Saido, Takaomi C.; Muyldermans, Serge; Liston, Adrian; De Strooper, Bart; Holt, Matthew G.

Neurotoxicity of four frequently used nanoparticles: a systematic review to reveal the missing data

ARCHIVES OF TOXICOLOGY

IF6.9

2022-03-12

PREAI

Gong, Jia-You; Holt, Matthew G.; Hoet, Peter H. M.; Ghosh, Manosij

研究方向