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N

Nathan Beutler

Department of Immunology and Microbiology
H指数:26
被引数:5,484

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mRNA delivery of circumsporozoite protein epitope-based malaria vaccines induces protection in a mouse model

基于环子孢子蛋白表位的疟疾疫苗的mRNA递送在鼠模型中诱导保护作用

npj Vaccines
IF6.5
2025-11-180
OAAI
Nelson R. Wu; Nathan Beutler; Xiaozhen Hu; Patrick D. Skog; Alessia Liguori; Yevel Flores-Garcia; Laura Maiorino; Sierra Terada; Danny Lu; Yen-Chung Lai; Justin Ndihokubwayo; Torben Schiffner; Christopher A. Cottrell; Saman Eskandarzadeh; Nushin Alavi; Michael Kubitz; Nicole Phelps; Ryan Tingle; Sam Hodges; John E. Youhanna; Sonya Amirzehni; Darrell J. Irvine; Sunny Himansu; Fidel Zavala; Thomas F. Rogers; Dennis R. Burton; William R. Schief
Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
PLOS PATHOGENS
IF4.9
2025-01-230
OAAI
Edwards, Christopher T.; Karunakaran, Kirti A.; Garcia, Elijah; Beutler, Nathan; Gagne, Matthew; Golden, Nadia; Aoued, Hadj; Pellegrini, Kathryn L.; Burnett, Matthew R.; Honeycutt, Christopher Cole; Lapp, Stacey A.; Ton, Thang; Lin, Mark C.; Metz, Amanda; Bombin, Andrei; Goff, Kelly; Scheuermann, Sarah E.; Wilkes, Amelia; Wood, Jennifer S.; Ehnert, Stephanie; Weissman, Stacey; Curran, Elizabeth H.; Roy, Melissa; Dessasau, Evan; Paiardini, Mirko; Upadhyay, Amit A.; Moore, Ian N.; Maness, Nicholas J.; Douek, Daniel C.; Piantadosi, Anne; Andrabi, Raiees; Rogers, Thomas R.; Burton, Dennis R.; Bosinger, Steven E.
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead (vol 67, pg 2369, 2024)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-06-140
OAAI
Elshan, N. G. R. Dayan; Wolff, Karen C.; Riva, Laura; Woods, Ashley K.; Grabovyi, Gennadii; Wilson, Katy; Pedroarena, James; Ghorai, Sourav; Nazarian, Armen; Weiss, Frank; Liu, Yuyin; Mazumdar, Wrickban; Song, Lirui; Okwor, Neechi; Malvin, Jacqueline; Liu, Dongdong; Bakowski, Malina A.; Beutler, Nathan; Kirkpatrick, Melanie G.; Gebara-Lamb, Amal; Huang, Edward; Nguyen-Tran, Van T. B.; Chi, Victor; Li, Shuangwei; Rogers, Thomas F.; McNamara, Case W.; Gupta, Anil Kumar; Rahimi, Alireza; Chen, Jian Jeffrey; Joseph, Sean B.; Schultz, Peter G.; Chatterjee, Arnab K.
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes
CELL REPORTS
IF6.9
2024-06-011
OAAI
Hurtado, Jonathan; Rogers, Thomas F.; Jaffe, David B.; Adams, Bruce A.; Bangaru, Sandhya; Garcia, Elijah; Capozzola, Tazio; Messmer, Terrence; Sharma, Pragati; Song, Ge; Beutler, Nathan; He, Wanting; Dueker, Katharina; Musharrafieh, Rami; Burbach, Sarah; Truong, Alina; Stubbington, Michael J. T.; Burton, Dennis R.; Andrabi, Raiees; Ward, Andrew B.; Mcdonnell, Wyatt J.; Briney, Bryan
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-02-094
OAAI
Elshan, N. G. R. Dayan; Wolff, Karen C.; Riva, Laura; Woods, Ashley K.; Grabovyi, Gennadii; Wilson, Katy; Pedroarena, James; Ghorai, Sourav; Nazarian, Armen; Weiss, Frank; Liu, Yuyin; Mazumdar, Wrickban; Song, Lirui; Okwor, Neechi; Malvin, Jacqueline; Bakowski, Malina A.; Beutler, Nathan; Kirkpatrick, Melanie G.; Gebara-Lamb, Amal; Huang, Edward; Nguyen-Tran, Van T. B.; Chi, Victor; Li, Shuangwei; Rogers, Thomas F.; McNamara, Case W.; Gupta, Anil Kumar; Rahimi, Alireza; Chen, Jian Jeffrey; Joseph, Sean B.; Schultz, Peter G.; Chatterjee, Arnab K.
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection
NATURE COMMUNICATIONS
IF15.7
2023-07-286
OAAI
Martin, Gregory M.; Torres, Jonathan L.; Pholcharee, Tossapol; Oyen, David; Flores-Garcia, Yevel; Gibson, Grace; Moskovitz, Re'em; Beutler, Nathan; Jung, Diana D. D.; Copps, Jeffrey; Lee, Wen-Hsin; Gonzalez-Paez, Gonzalo; Emerling, Daniel; MacGill, Randall S.; Locke, Emily; King, C. Richter; Zavala, Fidel; Wilson, Ian A.; Ward, Andrew B.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease

广泛中和的anti-S2抗体可预防导致致命疾病的所有三种人类 β 冠状病毒

IMMUNITY
IF26.3
2023-03-0149
OAAI
Zhou, Panpan; Song, Ge; Liu, Hejun; Yuan, Meng; He, Wan-ting; Beutler, Nathan; Zhu, Xueyong; Tse, Longping V.; Martinez, David R.; Schafer, Alexandra; Anzanello, Fabio; Yong, Peter; Peng, Linghang; Dueker, Katharina; Musharrafieh, Rami; Callaghan, Sean; Capozzola, Tazio; Limbo, Oliver; Parren, Mara; Garcia, Elijah; Rawlings, Stephen A.; Smith, Davey M.; Nemazee, David; Jardine, Joseph G.; Safonova, Yana; Briney, Bryan; Rogers, Thomas F.; Wilson, Ian A.; Baric, Ralph S.; Gralinski, Lisa E.; Burton, Dennis R.; Andrabi, Raiees
Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

ACE2的靶向蛋白S-亚硝基化抑制SARS-CoV-2感染

NATURE CHEMICAL BIOLOGY
IF13.7
2022-09-2918
OA
Oh, Chang-ki; Nakamura, Tomohiro; Beutler, Nathan; Zhang, Xu; Pina-Crespo, Juan; Talantova, Maria; Ghatak, Swagata; Trudler, Dorit; Carnevale, Lauren N.; McKercher, Scott R.; Bakowski, Malina A.; Diedrich, Jolene K.; Roberts, Amanda J.; Woods, Ashley K.; Chi, Victor; Gupta, Anil K.; Rosenfeld, Mia A.; Kearns, Fiona L.; Casalino, Lorenzo; Shaabani, Namir; Liu, Hejun; Wilson, Ian A.; Amaro, Rommie E.; Burton, Dennis R.; Yates, John R.; Becker, Cyrus; Rogers, Thomas F.; Chatterjee, Arnab K.; Lipton, Stuart A.
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-08-1010
OAAI
He, Wan-Ting; Yuan, Meng; Callaghan, Sean; Musharrafieh, Rami; Song, Ge; Silva, Murillo; Beutler, Nathan; Lee, Wen-Hsin; Yong, Peter; Torres, Jonathan L.; Melo, Mariane; Zhou, Panpan; Zhao, Fangzhu; Zhu, Xueyong; Peng, Linghang; Huang, Deli; Anzanello, Fabio; Ricketts, James; Parren, Mara; Garcia, Elijah; Ferguson, Melissa; Rinaldi, William; Rawlings, Stephen A.; Nemazee, David; Smith, Davey M.; Briney, Bryan; Safonova, Yana; Rogers, Thomas F.; Dan, Jennifer M.; Zhang, Zeli; Weiskopf, Daniela; Sette, Alessandro; Crotty, Shane; Irvine, Darrell J.; Ward, Andrew B.; Wilson, Ian A.; Burton, Dennis R.; Andrabi, Raiees
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
NATURE IMMUNOLOGY
IF27.6
2022-06-0244
OA
He, Wan-ting; Musharrafieh, Rami; Song, Ge; Dueker, Katharina; Tse, Longping V.; Martinez, David R.; Schafer, Alexandra; Callaghan, Sean; Yong, Peter; Beutler, Nathan; Torres, Jonathan L.; Volk, Reid M.; Zhou, Panpan; Yuan, Meng; Liu, Hejun; Anzanello, Fabio; Capozzola, Tazio; Parren, Mara; Garcia, Elijah; Rawlings, Stephen A.; Smith, Davey M.; Wilson, Ian A.; Safonova, Yana; Ward, Andrew B.; Rogers, Thomas F.; Baric, Ralph S.; Gralinski, Lisa E.; Burton, Dennis R.; Andrabi, Raiees
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum
PLOS PATHOGENS
IF4.9
2022-03-2824
OAAI
Beutler, Nathan; Pholcharee, Tossapol; Oyen, David; Flores-Garcia, Yevel; MacGill, Randall S.; Garcia, Elijah; Calla, Jaeson; Parren, Mara; Yang, Linlin; Volkmuth, Wayne; Locke, Emily; Regules, Jason A.; Dutta, Sheetij; Emerling, Daniel; Early, Angela M.; Neafsey, Daniel E.; Winzeler, Elizabeth; King, Richter; Zavala, Fidel; Burton, Dennis R.; Wilson, Ian A.; Rogers, Thomas F.
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

人类抗体揭示了 β-冠状病毒刺突蛋白上的保守位点，并赋予了抵抗SARS-CoV-2感染的保护

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-03-23119
OAAI
Zhou, Panpan; Yuan, Meng; Song, Ge; Beutler, Nathan; Shaabani, Namir; Huang, Deli; He, Wan-Ting; Zhu, Xueyong; Callaghan, Sean; Yong, Peter; Anzanello, Fabio; Peng, Linghang; Ricketts, James; Parren, Mara; Garcia, Elijah; Rawlings, Stephen A.; Smith, Davey M.; Nemazee, David; Teijaro, John R.; Rogers, Thomas F.; Wilson, Ian A.; Burton, Dennis R.; Andrabi, Raiees
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-10-2075
OAAI
Cho, Hyeseon; Gonzales-Wartz, Kristina Kay; Huang, Deli; Yuan, Meng; Peterson, Mary; Liang, Janie; Beutler, Nathan; Torres, Jonathan L.; Cong, Yu; Postnikova, Elena; Bangaru, Sandhya; Talana, Chloe Adrienna; Shi, Wei; Yang, Eun Sung; Zhang, Yi; Leung, Kwanyee; Wang, Lingshu; Peng, Linghang; Skinner, Jeff; Li, Shanping; Wu, Nicholas C.; Liu, Hejun; Dacon, Cherrelle; Moyer, Thomas; Cohen, Melanie; Zhao, Ming; Lee, Frances Eun-Hyung; Weinberg, Rona S.; Douagi, Iyadh; Gross, Robin; Schmaljohn, Connie; Pegu, Amarendra; Mascola, John R.; Holbrook, Michael; Nemazee, David; Rogers, Thomas F.; Ward, Andrew B.; Wilson, Ian A.; Crompton, Peter D.; Tan, Joshua
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
NATURE COMMUNICATIONS
IF15.7
2021-10-18204
OAAI
Boras, Britton; Jones, Rhys M.; Anson, Brandon J.; Arenson, Dan; Aschenbrenner, Lisa; Bakowski, Malina A.; Beutler, Nathan; Binder, Joseph; Chen, Emily; Eng, Heather; Hammond, Holly; Hammond, Jennifer; Haupt, Robert E.; Hoffman, Robert; Kadar, Eugene P.; Kania, Rob; Kimoto, Emi; Kirkpatrick, Melanie G.; Lanyon, Lorraine; Lendy, Emma K.; Lillis, Jonathan R.; Logue, James; Luthra, Suman A.; Ma, Chunlong; Mason, Stephen W.; McGrath, Marisa E.; Noell, Stephen; Obach, R. Scott; O' Brien, Matthew N.; O'Connor, Rebecca; Ogilvie, Kevin; Owen, Dafydd; Pettersson, Martin; Reese, Matthew R.; Rogers, Thomas F.; Rosales, Romel; Rossulek, Michelle I.; Sathish, Jean G.; Shirai, Norimitsu; Steppan, Claire; Ticehurst, Martyn; Updyke, Lawrence W.; Weston, Stuart; Zhu, Yuao; White, Kris M.; Garcia-Sastre, Adolfo; Wang, Jun; Chatterjee, Arnab K.; Mesecar, Andrew D.; Frieman, Matthew B.; Anderson, Annaliesa S.; Allerton, Charlotte
Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19
ELIFE
IF0
2021-08-1363
OA
Tindle, Courtney; Fuller, MacKenzie; Fonseca, Ayden; Taheri, Sahar; Ibeawuchi, Stella-Rita; Beutler, Nathan; Katkar, Gajanan Dattatray; Claire, Amanraj; Castillo, Vanessa; Hernandez, Moises; Russo, Hana; Duran, Jason; Alexander, Laura E. Crotty; Tipps, Ann; Lin, Grace; Thistlethwaite, Patricia A.; Chattopadhyay, Ranajoy; Rogers, Thomas F.; Sahoo, Debashis; Ghosh, Pradipta; Das, Soumita
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
NATURE COMMUNICATIONS
IF15.7
2021-06-0390
OAAI
Bakowski, Malina A.; Beutler, Nathan; Wolff, Karen C.; Kirkpatrick, Melanie G.; Chen, Emily; Nguyen, Tu-Trinh H.; Riva, Laura; Shaabani, Namir; Parren, Mara; Ricketts, James; Gupta, Anil K.; Pan, Kastin; Kuo, Peiting; Fuller, MacKenzie; Garcia, Elijah; Teijaro, John R.; Yang, Linlin; Sahoo, Debashis; Chi, Victor; Huang, Edward; Vargas, Natalia; Roberts, Amanda J.; Das, Soumita; Ghosh, Pradipta; Woods, Ashley K.; Joseph, Sean B.; Hull, Mitchell V.; Schultz, Peter G.; Burton, Dennis R.; Chatterjee, Arnab K.; McNamara, Case W.; Rogers, Thomas F.
AI-guided discovery of the invariant host response to viral pandemics
EBIOMEDICINE
IF10.8
2021-06-0126
OAAI
Sahoo, Debashis; Katkar, Gajanan D.; Khandelwal, Soni; Behroozikhah, Mahdi; Claire, Amanraj; Castillo, Vanessa; Tindle, Courtney; Fuller, MacKenzie; Taheri, Sahar; Rogers, Thomas F.; Beutler, Nathan; Ramirez, Sydney, I; Rawlings, Stephen A.; Pretorius, Victor; Smith, David M.; Burton, Dennis R.; Alexander, Laura E. Crotty; Duran, Jason; Crotty, Shane; Dan, Jennifer M.; Das, Soumita; Ghosh, Pradipta
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
NATURE COMMUNICATIONS
IF15.7
2021-05-19129
OAAI
Song, Ge; He, Wan-ting; Callaghan, Sean; Anzanello, Fabio; Huang, Deli; Ricketts, James; Torres, Jonathan L.; Beutler, Nathan; Peng, Linghang; Vargas, Sirena; Cassell, Jon; Parren, Mara; Yang, Linlin; Ignacio, Caroline; Smith, Davey M.; Voss, James E.; Nemazee, David; Ward, Andrew B.; Rogers, Thomas; Burton, Dennis R.; Andrabi, Raiees
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
CELL REPORTS
IF6.9
2021-04-0173
OAAI
Garcia, Gustavo, Jr.; Sharma, Arun; Ramaiah, Arunachalam; Sen, Chandani; Purkayastha, Arunima; Kohn, Donald B.; Parcells, Mark S.; Beck, Sebastian; Kim, Heeyoung; Bakowski, Malina A.; Kirkpatrick, Melanie G.; Riva, Laura; Wolff, Karen C.; Han, Brandon; Yuen, Constance; Ulmert, David; Purbey, Prabhat K.; Scumpia, Phillip; Beutler, Nathan; Rogers, Thomas F.; Chatterjee, Arnab K.; Gabriel, Guelsah; Bartenschlager, Ralf; Gomperts, Brigitte; Svendsen, Clive N.; Betz, Ulrich A. K.; Damoiseaux, Robert D.; Arumugaswami, Vaithilingaraja

研究方向

暂未获取到该数据
T
Thomas F. Rogers
H 指数:30论文数:101被引数:7,360
D
Dennis R. Burton
H 指数:172论文数:807被引数:10.0万
E
Elijah Garcia
H 指数:12论文数:20被引数:2,269
M
Mara Parren
H 指数:14论文数:24被引数:2,794
I
Ian A. Wilson
H 指数:179论文数:1,704被引数:12.1万
R
Raiees Andrabi
H 指数:30论文数:121被引数:5,016
D
Davey M. Smith
H 指数:82论文数:586被引数:4.0万
A
Arnab K. Chatterjee
H 指数:51论文数:162被引数:1.0万
M
Malina A. Bakowski
H 指数:24论文数:56被引数:3,736
何婉婷 封面图
何婉婷
H 指数:31论文数:127被引数:8,748