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Ali A. Ashkar

mcmaster immunology research centre

56H指数
216论文数
1.1W被引数
收录论文 123
发表时间
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Expanded NK and fratricide-resistant CD70 CAR-NK cells are potent against patient-derived glioblastoma cells in vitro and in vivo扩增的NK细胞和抗 fratricide 的CD70 CAR-NK细胞在体外和体内对来自患者的胶质母细胞瘤细胞具有显著作用
errCancer Immunology Immunotherapy
IF5.1
err2026-08-31
err0
errOAAI
errMisaal Mehboob; Matthew Rätsep; Adnan Moinuddin; Ana Portillo; Fatemeh Vahedi; Mohammadamin Sookhaklari; Ella C. Troy; Yasemin Sezgin; Vaseem Shaikh; William Maich; Chitra Venugopal; Meisam Naeimi Kararoudi; Dean A. Lee; Sheila K. Singh; Ali A. Ashkar
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Inactivation of interleukin-15 reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice白介素-15失活可降低载脂蛋白E缺陷小鼠的自发性动脉粥样硬化
errFrontiers in Physiology
IF3.4
err2026-08-05
err0
errOAAI
errOD Omid Dadoo †; BS B. Sumayyah H. Sokeechand †; AL Anna Lee †; MT Mark T. Fuller; YC Yu Chang David Wang; ME Melissa E. MacDonald; NL Nicole L. Batenburg; SA Suleiman A. Igdoura; CD Carl D. Richards; AA Ali A. Ashkar; BL Bernardo L. Trigatti
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Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis基于机器学习赋能的靶细胞死亡分析的液滴微流控技术对NK细胞细胞毒性的表征
errlab chip
IF0
err2026-05-14
err0
errOAAI
errRana S. Ozcan; Fatemeh Vahedi; Shina Namakian; Ali A. Ashkar; Tohid F. Didar
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Maternal Diet-Induced Excess Adiposity in Mice Disrupts Mid-Gestation Decidual Immune and Vascular Homeostasis Without Impairing Spiral Artery Remodeling孕期饮食诱导的小鼠过多脂肪堆积扰乱了孕中期蜕膜免疫和血管稳态，但未损害螺旋动脉重塑
errACTA PHYSIOLOGICA
IF5.6
err2025-12-01
err0
errOAAI
errBellissimo, Christian J.; Yeo, Erica; Ribeiro, Tatiane A.; Jazwiec, Patrycja A.; Ellewela, Chethana; Bains, Jaskiran; Lewis, Ariana E.; Kennedy, Katherine M.; Ashkar, Ali A.; Beristain, Alexander G.; Bowdish, Dawn M. E.; Sloboda, Deborah M.
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Development of an IL-21 based TriKE for in vivo NK cell expansion and cytotoxicity against solid tumors
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errMoinuddin, Adnan; Vahedi, Fatemeh; Rossotti, Martin A.; Henry, Kevin A.; Ashkar, Ali A.
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Investigating the cytotoxicity of expanded NK and CD70-targeting CAR-NK cells against brain tumor cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errMehboob, Misaal; Ratsep, Matthew; Portillo, Ana; Sezgin, Yasemin; Shaikh, Vaseem; Kararoudi, Meisam Naeimi; Singh, Sheila; Ashkar, Ali A.
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Microglia promote bystander activated T cell-mediated neurological disease during viral infection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBalint, Elizabeth; Feng, Emily; Montemarano, Amelia; Monteiro, Jonathan; Giles, Elizabeth C.; Ritchie, Tyrah; Qian, Alexander S.; Vahedi, Fatemeh; Portillo, Ana; Miron, Veronique; Trigatti, Bernardo L.; Ashkar, Ali A.
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Development of human ex vivo expanded Vδ1 γδ T cells armed with CAR as a metabolically fit, off-the-shelf cell therapy for solid tumors
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errPortillo, Ana; Mehboob, Misaal; Sezgin, Yasemin; Kararoudi, Meisam; Ashkar, Ali A.
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Dysregulated glucose metabolism drives hyperinflammation and immune-mediated pathology during viral infection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errMansour, Alexa; Feng, Emily; Poznanski, Sophie; Balint, Elizabeth; Ashkar, Ali A.
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err收藏
Mucosal delivery of interferon-? Alters the local cytokine environment to inhibit hyperinflammation and boost immunity to HSV-2 infection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errFeng, Emily; Balint, Elizabeth; Tramonte, Sofia; Monteiro, Jonathan; Mansour, Alexa; Portillo, Ana; Santer, Deanna M.; Kotenko, Sergei; Ashkar, Ali A.
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The Critical Role of Type I Interferons in Murine Hepatitis Virus Proliferation and Liver Pathology
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errVahedi, Fatemeh Leila; Feng, Emily; Mahabir, Seshini; Ashkar, Ali A.
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Oral cannabis disrupts uterine NK cell function leading to impaired decidual vessel remodeling and fetal growth in mice
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errRitchie, Tyrah; Feng, Emily; Vahedi, Fatemeh; Ermolina, Sofya; Bellissimo, Christian; De Jong, Erica; Portillo, Ana; Poznanski, Sophie; Chan, Lauren; Ettehadieh, Sara; Sloboda, Deborah; Bowdish, Dawn M. E.; Ashkar, Ali A.
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IL-21-reprogrammed Vδ1 T cells exert killing against solid tumors which is enhanced by CAR arming for off-the-shelf immunotherapyIL-21-reprogrammed Vδ1 T细胞对实体瘤具有杀伤作用，该作用可通过CAR改造增强，以用于现货型免疫疗法。
errOncoImmunology
IF6.3
err2025-09-25
err0
errOAAI
errAna L. Portillo; Misaal Mehboob; Genesis Snyder; Adnan Moinuddin; Tyrah M. Ritchie; Elizabeth Balint; Allyson E. Moore; Mohammadamin Sookhaklari; Jonathan L. Bramson; Dean A. Lee; Meisam Naeimi Kararoudi; Ali A. Ashkar
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NASH-related Hepatocellular carcinoma: current therapeutic approaches and the emerging role of sodium homeostasis as a novel targeting strategyNASH相关的肝细胞癌：当前的治疗方法以及钠稳态作为新型靶向策略的兴起作用
errFrontiers in Pharmacology
IF4.8
err2025-09-04
err0
errOAAI
errAbdulsalam Ashkar; Simone Fiorilla; Francesco Tasso; Rita Carini
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Biological Sex Influences Human Bystander CD8+ T Cell Activation生物学性别影响人类旁观者CD8+ T细胞活化
errEuropean Journal of Immunology
IF3.7
err2025-06-24
err0
PREAI
errElizabeth Balint; Marie Joe Adaimy; Amelia Montemarano; Ana L. Portillo; Ali A. Ashkar
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The impact of oral cannabis consumption during pregnancy on maternal spiral artery remodelling, fetal growth and offspring behaviour in mice孕期口服大麻对母体螺旋动脉重塑、胎儿生长及子代行为的影响（小鼠研究）
errEBIOMEDICINE
IF10.8
err2025-02-01
err2
errOAAI
errRitchie, Tyrah M.; Feng, Emily; Vahedi, Fatemeh; Ermolina, Sofya; Bellissimo, Christian J.; De Jong, Erica; Portillo, Ana L.; Poznanski, Sophie M.; Chan, Lauren; Ettehadieh, Sara M.; Sloboda, Deborah M.; Bowdish, Dawn M. E.; Ashkar, Ali A.
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Late Breaking Abstract- Benralizumab reduces eosinophils and ANCA in sputum in EGPA
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2024-10-30
err0
PREAI
errMukherjee, Manali; Tan, Nadia Suray; Huang, Chynna; Kim, Brian; Radford, Katherine; Garrido, Carmen Venegas; Bhalla, Anurag; Rodriguez-Suarez, Eva; Wechsler, Michael; Walker, Brandie; Sjo, Lena Borjesson; Necander, Sofia; Ashkar, Ali; Weidner, Julie; Sehmi, Roma; Mccrae, Christopher; Khalidi, Nader; Nair, Parameswaran
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CD56 does not contribute to the antitumor, tissue homing, and glycolytic capacity of human NK cells
errJOURNAL OF LEUKOCYTE BIOLOGY
IF3.1
err2024-10-25
err0
PREAI
errPortillo, Ana L.; Rojas, Eduardo A.; Mehboob, Misaal; Moinuddin, Adnan; Balint, Elizabeth; Feng, Emily; Silvestri, Christopher; Vahedi, Fatemeh; Ritchie, Tyrah M.; Mansour, Alexa J.; Bramson, Jonathan L.; Ashkar, Ali A.
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Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment
errIMMUNOLOGICAL REVIEWS
IF8.3
err2024-03-09
err6
PREAI
errMoinuddin, Adnan; Poznanski, Sophie M.; Portillo, Ana L.; Monteiro, Jonathan K.; Ashkar, Ali A.
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Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity
errNATURE COMMUNICATIONS
IF15.7
err2024-02-05
err5
errOAAI
errBalint, Elizabeth; Feng, Emily; Giles, Elizabeth C.; Ritchie, Tyrah M.; Qian, Alexander S.; Vahedi, Fatemeh; Montemarano, Amelia; Portillo, Ana L.; Monteiro, Jonathan K.; Trigatti, Bernardo L.; Ashkar, Ali A.
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研究方向

暂时未获取到该数据
合作学者
合作期刊
N
Nahum Sonenberg
H 指数: 178 · 论文数: 957
N
Nico van Rooijen
H 指数: 165 · 论文数: 1.0K
M
Michael Diamond
H 指数: 160 · 论文数: 1.5K
P
Peter Palese
H 指数: 141 · 论文数: 591
K
Katherine A. Fitzgerald
H 指数: 136 · 论文数: 609
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