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Tumor Associated Mitochondria Antigens (TAMAs) vaccine is effective on tumor and tumor associated endothelial cells: from the mechanisms to the clinical validation Costabile, Francesca; Pierini, Stefano; Linares, Renzo Perales; Bear, Adham; Koch, Cameron; Linette, Gerald; Carreno, Beatriz M.; Lotz, Michael; Koumenis, Costantinos; Facciabene, Andrea 分享 收藏
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FLASH proton reirradiation, with or without hypofractionation, reduces chronic toxicity in the normal murine intestine, skin, and bone Verginadis, Ioannis I.; Velalopoulou, Anastasia; Kim, Michele M.; Kim, Kyle; Paraskevaidis, Ioannis; Bell, Brett; Motlagh, Seyyedeh Azar Oliaei; Karaj, Antoneta; Banerjee, Esha; Finesso, Giovanni; Assenmacher, Charles-Antoine; Radaelli, Enrico; Lu, Jiawei; Lin, Yuewei; Putt, Mary E.; Diffenderfer, Eric S.; Guha, Chandan; Qin, Ling; Metz, James M.; Maity, Amit; Cengel, Keith A.; Koumenis, Constantinos; Busch, Theresa M. 分享 收藏
The radiogenomic and spatiogenomic landscapes of glioblastoma and their relationship to oncogenic drivers Fathi Kazerooni, Anahita; Akbari, Hamed; Hu, Xiaoju; Bommineni, Vikas; Grigoriadis, Dimitris; Toorens, Erik; Sako, Chiharu; Mamourian, Elizabeth; Ballinger, Dominique; Sussman, Robyn; Singh, Ashish; Verginadis, Ioannis I.; Dahmane, Nadia; Koumenis, Constantinos; Binder, Zev A.; Bagley, Stephen J.; Mohan, Suyash; Hatzigeorgiou, Artemis; O'Rourke, Donald M.; Ganguly, Tapan; De, Subhajyoti; Bakas, Spyridon; Nasrallah, MacLean P.; Davatzikos, Christos 分享 收藏
Local radiation enhances systemic CAR T-cell efficacy by augmenting antigen crosspresentation and T-cell infiltration Kostopoulos, Nektarios; Costabile, Francesca; Krimitza, Elisavet; Beghi, Silvia; Goia, Denisa; Perales-Linares, Renzo; Thyfronitis, George; Lariviere, Michael J.; Chong, Elise A.; Schuster, Stephen J.; Maity, Amit; Koumenis, Constantinos; Plastaras, John P.; Facciabene, Andrea 分享 收藏
SUBTYPING GLIOBLASTOMA FROM JOINT CLUSTERING OF IMAGING AND GENOMIC DATA Guo, Jun; Fathi-Kazerooni, Anahita; Toorens, Erik; Akbari, Hamed; Yu, Fanyang; Matsumoto, Yuji; Sako, Chiharu; Mamourian, Elizabeth; Shinohara, Russell; Koumenis, Constantinos; Verginadis, Ioannis; Bagley, Stephen; Morrissette, Jennifer; Binder, Zev; Brem, Steven; Mohan, Suyash; Lustig, Robert; O'Rourke, Donald; Ganguly, Tapan; Bakas, Spyridon; Aboian, Mariam; Nasrallah, Maclean; Davatzikos, Christos 分享 收藏
Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19 Ha, Dat P.; Shin, Woo-Jin; Liu, Ze; Doche, Michael E.; Lau, Roy; Leli, Nektaria Maria; Conn, Crystal S.; Russo, Mariangela; Lorenzato, Annalisa; Koumenis, Constantinos; Yu, Min; Mumenthaler, Shannon M.; Lee, Amy S. 分享 收藏
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies 改良的C型利钠肽使肿瘤血管正常化，重振抗肿瘤免疫力，并改善实体瘤治疗 Lu, Zhen; Verginadis, Ioannis; Kumazoe, Motofumi; Castillo, Gerardo M.; Yao, Yao; Guerra, Rebecca E.; Bicher, Sandra; You, Menghao; Mcclung, George; Qiu, Rong; Xiao, Zebin; Miao, Zhen; George, Subin S.; Beiting, Daniel P.; Nojiri, Takashi; Tanaka, Yasutake; Fujimura, Yoshinori; Onda, Hiroaki; Hatakeyama, Yui; Nishimoto-Ashfield, Akiko; Bykova, Katrina; Guo, Wei; Fan, Yi; Buynov, Nikolay M.; Diehl, J. Alan; Stanger, Ben Z.; Tachibana, Hirofumi; Gade, Terence P.; Pure, Ellen; Koumenis, Constantinos; Bolotin, Elijah M.; Fuchs, Serge Y. 分享 收藏
Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy Logotheti, Stella; Pavlopoulou, Athanasia; Rudsari, Hamid Khoshfekr; Galow, Anne-Marie; Kafal, Yagmur; Kyrodimos, Efthymios; Giotakis, Aris I.; Marquardt, Stephan; Velalopoulou, Anastasia; Verginadis, Ioannis I.; Koumenis, Constantinos; Stiewe, Thorsten; Zoidakis, Jerome; Balasingham, Ilangko; David, Robert; Georgakilas, Alexandros G. 分享 收藏
Proton radiation boosts the efficacy of mesothelin- targeting chimeric antigen receptor T cell therapy in pancreatic cancer Amit, Uri; Uslu, Ugur; Verginadis, Ioannis I.; Kim, Michele M.; Motlagh, Seyyedeh Azar Oliaei; Diffenderfer, Eric S.; Assenmacher, Charles-Antoine; Bicher, Sandra; Atoche, Sebastian J.; Ben-Josef, Edgar; Young, Regina M.; June, Carl H.; Koumenis, Constantinos 分享 收藏
FLASH Proton Radiation Therapy Mitigates In fl ammatory and Fibrotic Pathways and Preserves Cardiac Function in a Preclinical Mouse Model of Radiation-Induced Heart Disease 在辐射诱发的心脏病的临床前小鼠模型中，快速质子放射治疗减轻了炎症和纤维化途径，并保留了心脏功能 Kim, Kyle; Kim, Michele M.; Skoufos, Giorgos; Diffenderfer, Eric S.; Motlagh, Seyyedeh Azar Oliaei; Kokkorakis, Michail; Koliaki, Ilektra; Morcos, George; Shoniyozov, Khayrullo; Griffi, Joanna; Hatzigeorgiou, Artemis G.; Metz, James M.; Lin, Alexander; Feigenberg, Steven J.; Cengel, Keith A.; Ky, Bonnie; Koumenis, Constantinos; Verginadis, Ioannis I. 分享 收藏
Proton FLASH Radiotherapy Ameliorates Radiation-induced Salivary Gland Dysfunction and Oral Mucositis and Increases Survival in a Mouse Model of Head and Neck Cancer 质子闪光放射治疗可改善辐射诱发的唾液腺功能障碍和口腔粘膜炎，并提高头颈癌小鼠模型的生存率 Chowdhury, Priyanka; Velalopoulou, Anastasia; Verginadis, Ioannis I.; Morcos, George; Loo, Phoebe E.; Kim, Michele M.; Motlagh, Seyyedeh Azar Oliaei; Shoniyozov, Khayrullo; Diffenderfer, Eric S.; Ocampo, Emilio A.; Putt, Mary; Assenmacher, Charles-Antoine; Radaelli, Enrico; Lu, Jiawei; Qin, Ling; Liu, Hengxi; Leli, Nektaria Maria; Girdhani, Swati; Denef, Nicolas; Vander Stappen, Francois; Cengel, Keith A.; Busch, Theresa M.; Metz, James M.; Dong, Lei; Lin, Alexander; Koumenis, Constantinos 分享 收藏
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury p53促进严重辐射损伤后再生肠道中的再生干细胞 Morral, Clara; Ayyaz, Arshad; Kuo, Hsuan-Cheng; Fink, Mardi; Verginadis, Ioannis I.; Daniel, Andrea R.; Burner, Danielle N.; Driver, Lucy M.; Satow, Sloane; Hasapis, Stephanie; Ghinnagow, Reem; Luo, Lixia; Ma, Yan; Attardi, Laura D.; Koumenis, Constantinos; Minn, Andy J.; Wrana, Jeffrey L.; Lee, Chang-Lung; Kirsch, David G. 分享 收藏
A genome-wide CRISPR-based functional screen uncovers the KLF4-Survivin/BIRC5 signaling pathways as a key regulator of cell fate following endoplasmic reticulum stress: Implications for tumor growth and therapeutic targeting Leli, Nektaria M.; Liu, Hengxi; Dey, Souvik; Brady, Lauren; Salinas, Carlo Salas; Wu, Victoria; Tastsoglou, Spiros; Skoufos, Giorgos; Verginadis, Ioannis; Karagounis, Ilias; Hatzigeorgiou, Artemis G.; Koumenis, Constantinos 分享 收藏
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An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma 免疫抑制性血管生态位驱动胶质母细胞瘤中的巨噬细胞极化和免疫治疗抵抗 Yang, Fan; Akhtar, Md Naushad; Zhang, Duo; El-Mayta, Rakan; Shin, Junyoung; Dorsey, Jay F.; Zhang, Lin; Xu, Xiaowei; Guo, Wei; Bagley, Stephen J.; Fuchs, Serge Y.; Koumenis, Constantinos; Lathia, Justin D.; Mitchell, Michael J.; Gong, Yanqing; Fan, Yi 分享 收藏
Integrating imaging and genomic data for the discovery of distinct glioblastoma subtypes: a joint learning approach Guo, Jun; Fathi Kazerooni, Anahita; Toorens, Erik; Akbari, Hamed; Yu, Fanyang; Sako, Chiharu; Mamourian, Elizabeth; Shinohara, Russell T.; Koumenis, Constantinos; Bagley, Stephen J.; Morrissette, Jennifer J. D.; Binder, Zev A.; Brem, Steven; Mohan, Suyash; Lustig, Robert A.; O'Rourke, Donald M.; Ganguly, Tapan; Bakas, Spyridon; Nasrallah, MacLean P.; Davatzikos, Christos 分享 收藏
Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance Perales-Linares, Renzo; Leli, Nektaria Maria; Mohei, Hesham; Beghi, Silvia; Rivera, Osvaldo D.; Kostopoulos, Nektarios; Giglio, Andrea; George, Subin S.; Uribe-Herranz, Mireia; Costabile, Francesca; Pierini, Stefano; Pustylnikov, Sergei; Skoufos, Giorgos; Barash, Yoseph; Hatzigeorgiou, Artemis G.; Koumenis, Constantinos; Maity, Amit; Lotze, Michael T.; Facciabene, Andrea 分享 收藏
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