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S

Sarah L. Gaffen

pennsylvania commonwealth system of higher education (pcshe)

76H指数
329论文数
2.4W被引数
收录论文 139
发表时间
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IL-1 family signalling drives mucosal defence against systemic Candida albicans infectionIL-1家族信号驱动黏膜防御系统性白色念珠菌感染
errNature Microbiology
IF19.4
err2026-08-05
err0
errOAAI
errJames S. Griffiths; Alexander Kempf; Robert J. Pickering; Emily L. Priest; Olivia K. A. Paulin; Léa Lortal; Andrew Donkin; Olivia W. Hepworth; Don N. Wickramasinghe; Aize Pellon; Paul A. Stevens; Leanne Farnan; Adrian Lau; Harun Papini; Pawan Dhami; Sarah L. Gaffen; Jonathan P. Richardson; Julian R. Naglik
err分享
err收藏
The tissue-specific regulation of immunobiology by IL-17 signalingIL-17信号对免疫生物学的组织特异性调控
errScience Immunology
IF16.3
err2026-06-12
err0
PREAI
errYang Li; Shachi P. Vyas; Peter Draber; Rami Bechara; Sarah L. Gaffen
err分享
err收藏
An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicansIL-17-DUOX2轴调控白色念珠菌的胃肠道定植
errNature Communications
IF15.7
err2026-05-04
err0
errOAAI
errPallavi Kakade; Juan F. Burgueno; Shabnam Sircaik; Nicole O. Ponde; Jinke Li; Iuliana V. Ene; Jiwoong Kim; Shen-Huan Liang; Rebecca Yunker; Ipsita Dey; Yasutada Akiba; Shipra Vaishnava; Jonathan D. Kaunitz; Sing Sing Way; Andrew Y. Koh; Sarah L. Gaffen; Maria T. Abreu; Richard J. Bennett
err分享
err收藏
An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen白细胞介素-1、白细胞介素-17和白细胞介素-22细胞因子回路在独立于雌激素的情况下控制外阴阴道念珠菌病
errPLoS Pathogens
IF4.9
err2026-05-01
err0
PREAI
errColeman, Bianca M.; Cook, Melissa E.; Khan, Md. Robin; Vogel, Amanda K.; Wells, Anthony J.; Miao, Jian; Vyas, Shachi P.; Taylor, Tiffany C.; Aggor, Felix E. Y.; Ponde, Nicole O.; Dey, Ipsita; Zou, Henry; Jasarevic, Eldin; Peters, Brian M.; Gaffen, Sarah L.
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Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance非经典IL‑22受体信号通路在白色念珠菌免疫监视期间重塑口腔黏膜屏障
errNature Communications
IF15.7
err2026-04-03
err0
errOAAI
errNicolas Millet; Jinendiran Sekar; Norma V. Solis; Jian Miao; Antoine Millet; Felix E. Y. Aggor; Asia Wildeman; Melissa E. Cook; Amirhossein Davari; Brian M. Peters; Michail S. Lionakis; Sarah L. Gaffen; Nicholas Jendzjowsky; Scott G. Filler; Marc Swidergall
err分享
err收藏
The RNA binding protein Arid5a is an activator of TNF signaling in rheumatoid arthritisArid5a RNA结合蛋白是类风湿关节炎中TNF信号通路的激活剂
errJCI Insight
IF6.1
err2026-01-23
err0
PREAI
errLi, Yang; Dey, Ipsita; Vyas, Shachi P.; Synackova, Alzbeta; Li, Decheng; Lubberts, Erik; Ascherman, Dana P.; Draber, Peter; Gaffen, Sarah L.
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Therapeutic delivery of CCL2 modulates immune response and restores host-microbe homeostasisCCL2的治疗性递送调节免疫应答并恢复宿主-微生物稳态
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-08-26
err0
PREAI
errShehabeldin, Mostafa; Gao, Jin; Cho, Yejin; Chong, Rong; Tabib, Tracy; Li, Lu; Smardz, Matthew; Gaffen, Sarah L.; Diaz, Patricia I.; Lafyatis, Robert; Little, Steven R.; Sfeir, Charles
err分享
err收藏
C/EBPB Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-07-31
err1
PREAI
errDey, Ipsita; Li, Yang; Taylor, Tiffany C.; Peroumal, Doureradjou; Asada, Nariaki; Panzer, Ulf; Biswas, Partha S.; Sterneck, Esta; Gaffen, Sarah L.
err分享
err收藏
The RNA binding protein Arid5a drives IL-17-dependent autoantibody-induced glomerulonephritis
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2024-07-26
err2
PREAI
errLi, Yang; Vyas, Shachi P.; Mehta, Isha; Asada, Nariaki; Dey, Ipsita; Taylor, Tiffany C.; Bechara, Rami; Amatya, Nilesh; Aggor, Felix E. Y.; Coleman, Bianca M.; Li, De-Dong; Yamamoto, Kenta; Ezenwa, Ogechukwu; Sun, Yeque; Sterneck, Esta; McManus, C. Joel; Panzer, Ulf; Biswas, Partha S.; Savan, Ram; Das, Jishnu; Gaffen, Sarah L.
err分享
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Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs
errPLOS PATHOGENS
IF4.9
err2024-07-01
err3
errOAAI
errAggor, Felix E. Y.; Bertolini, Martinna; Coleman, Bianca M.; Taylor, Tiffany C.; Ponde, Nicole O.; Gaffen, Sarah L.
err分享
err收藏
Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint人类IL-17A蛋白的产生是通过pip5k1α 依赖性翻译检查点控制的
errSCIENCE SIGNALING
IF6.6
err2023-10-24
err0
errOAAI
errRevu, Shankar K.; Yang, Wenjuan; Rajasundaram, Dhivyaa; Brady, Alexander; Majumder, Saikat; Gaffen, Sarah L.; Hawse, William; Xia, Zongqi; McGeachy, Mandy J.
err分享
err收藏
SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-06-02
err7
errOAAI
errPonde, Nicole O.; Shoger, Karsen E.; Khatun, Mst Shamima; Sarkar, Mrinal K.; Dey, Ipsita; Taylor, Tiffany C.; Cisney, Rylee N.; Arunkumar, Samyuktha P.; Gudjonsson, Johann E.; Kolls, Jay K.; Gottschalk, Rachel A.; Gaffen, Sarah L.
err分享
err收藏
1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A1，25-二羟基维生素D3通过转录调节Interleukin-17A改善Th17自身免疫
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err421
errOAAI
errJoshi, Sneha; Pantalena, Luiz-Carlos; Liu, Xikui K.; Gaffen, Sarah L.; Liu, Hong; Rohowsky-Kochan, Christine; Ichiyama, Kenji; Yoshimura, Akihiko; Steinman, Lawrence; Christakos, Sylvia; Youssef, Sawsan
err分享
err收藏
Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-10-01
err13
errOAAI
errPonde, Nicole O.; Lortal, Lea; Tsavou, Antzela; Hepworth, Olivia W.; Wickramasinghe, Don N.; Ho, Jemima; Richardson, Jonathan P.; Moyes, David L.; Gaffen, Sarah L.; Naglik, Julian R.
err分享
err收藏
A gut-oral microbiome-driven axis controls oropharyngeal candidiasis through retinoic acid
errJCI INSIGHT
IF6.1
err2022-09-22
err10
errOAAI
errAggor, Felix E. Y.; Bertolini, Martinna; Zhou, Chunsheng; Taylor, Tiffany C.; Abbott, Darryl A.; Musgrove, Javonn; Bruno, Vincent M.; Hand, Timothy W.; Gaffen, Sarah L.
err分享
err收藏
Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-09-15
err4
errOAAI
errTaylor, Tiffany C.; Li, Yang; Li, De-Dong; Majumder, Saikat; McGeachy, Mandy J.; Biswas, Partha S.; Gingras, Sebastien; Gaffen, Sarah L.
err分享
err收藏
Th17-driven immunity to oral candidiasis is dependent on the microbiome and can be triggered by mono-colonization with segmented filamentous bacteria
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-05-01
err1
PREAI
errAggor, Felix E. Y.; Zhou, Chunsheng; Abbott, Darryl; Musgrove, Javonn; Bruno, Vincent; Hand, Timothy W.; Gaffen, Sarah L.
err分享
err收藏
The Candida albicans toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways
errSCIENCE SIGNALING
IF6.6
err2022-04-05
err26
errOAAI
errNikou, Spyridoula-Angeliki; Zhou, Chunsheng; Griffiths, James S.; Kotowicz, Natalia K.; Coleman, Bianca M.; Green, Mary J.; Moyes, David L.; Gaffen, Sarah L.; Naglik, Julian R.; Parker, Peter J.
err分享
err收藏
Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon ResponseRegnase-1缺乏通过调节I型干扰素反应抑制肺炎克雷伯菌感染
errMBIO
IF4.7
err2022-02-22
err2
errOAAI
errTrevejo-Nunez, Giraldina; Lin, Becky; Fan, Li; Aggor, Felix E. Y.; Biswas, Partha S.; Chen, Kong; Gaffen, Sarah L.
err分享
err收藏
The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammationRNA结合蛋白IMP2在自身免疫性神经炎症中驱动stromal-Th17细胞回路
errJCI INSIGHT
IF6.1
err2022-02-08
err11
errOAAI
errBechara, Rami; Amatya, Nilesh; Majumder, Saikat; Zhou, Chunsheng; Li, Yang; Liu, Qixing; McGeachy, Mandy J.; Gaffen, Sarah L.
err分享
err收藏

研究方向

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合作学者
合作期刊
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L
Lawrence Steinman
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