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T

Taro Hitosugi

Mayo Clinic
H指数:26
被引数:4,354

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Alpha-aminoadipate in the saccharopine pathway promotes cancer metastasis through sumoylation of transcription machinery

α-氨基己二酸通过泛素化转录机器促进糖胺途径中的癌症转移

Nature Communications
IF15.7
2026-11-040
OAAI
JiHoon Kang; Jung Seok Hwang; Jaehyun Kim; Kiyoung Eun; Chaoyun Pan; Sydney Shuff; Junghui Koo; Vanessa Avalos; Melissa Gilbert-Ross; Hannah E. Bacho; Jennifer M. Robertson; Gabriel Sica; Tianna M. Espe; Sadae Hitosugi; Lingtao Jin; Conor E. Steuer; Adam I. Marcus; Cheng-Kui Qu; Andrey A. Ivanov; Taro Hitosugi; Sumin Kang
Mitochondrial metabolism and epigenetic crosstalk drive SASP

线粒体代谢与表观遗传学串扰驱动SASP

Nature
IF48.5
2026-07-290
OA
Hélène Martini; Jodie Birch; Francisco D. M. Marques; Stella Victorelli; Anthony B. Lagnado; Nicholas Pirius; Ana Catarina Franco; Gung Lee; Yeaeun Han; Jennifer L. Rowsey; Wazim Mohammed Ismail; Amelia Mazzone; Tianna M. Espe; Taro Hitosugi; Ya Li; Alexander M. Washington; Aaron Havas; Rabi Murad; Xue Lei; Rebecca A. Porritt; Oliver D. K. Maddocks; Jair Machado Espindola-Netto; Dominik Saul; Sundeep Khosla; Diana Jurk; Enis Kostallari; Alexandre Gaspar-Maia; Peter D. Adams; João F. Passos
Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling

非经典二氢硫辛酰胺转乙酰酶通过线粒体四氢叶酸信号促进化疗耐药性

Nature Communications
IF15.7
2025-10-080
OAAI
Jung Seok Hwang; JiHoon Kang; Jaehyun Kim; Kiyoung Eun; Sophia West; Hannah E. Bacho; Vanessa Avalos; Sydney Shuff; Dong M. Shin; Nabil F. Saba; Kelly R. Magliocca; Cheng-Kui Qu; Haian Fu; Suresh S. Ramalingam; Andrey A. Ivanov; Taro Hitosugi; Sumin Kang
Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8+ T cells via ME1 up-regulation

挽救疗法通过ME1上调来扩大高细胞毒性和代谢适应性CD8 T细胞

SCIENCE ADVANCES
IF12.5
2023-11-172
OAAI
Gicobi, Joanina K.; Mao, Zhiming; DeFranco, Grace; Hirdler, Jacob B.; Li, Ying; Vianzon, Vianca V.; Dellacecca, Emilia R.; Hsu, Michelle A.; Barham, Whitney; Yan, Yiyi; Mansfield, Aaron S.; Lin, Yi; Wu, Xiaosheng; Hitosugi, Taro; Owen, Dawn; Grams, Michael P.; Orme, Jacob J.; Lucien, Fabrice; Zeng, Hu; Park, Sean S.; Dong, Haidong
Fibroblast Growth Factor Receptor 3 Associates with and Tyrosine Phosphorylates p90 RSK2, Leading to RSK2 Activation That Mediates Hematopoietic Transformation
MOLECULAR AND CELLULAR BIOLOGY
IF2.7
2023-03-2157
OAAI
Kang, Sumin; Elf, Shannon; Dong, Shaozhong; Hitosugi, Taro; Lythgoe, Katherine; Guo, Ailan; Ruan, Hong; Lonial, Sagar; Khoury, Hanna J.; Williams, Ifor R.; Lee, Benjamin H.; Roesel, Johannes L.; Karsenty, Gerard; Hanauer, Andre; Taunton, Jack; Boggon, Titus J.; Gu, Ting-Lei; Chen, Jing
TFEB Links MYC Signaling to Epigenetic Control of Myeloid Differentiation and Acute Myeloid Leukemia
BLOOD CANCER DISCOVERY
IF11.5
2020-12-2122
OA
Yun, Seongseok; Vincelette, Nicole D.; Yu, Xiaoqing; Watson, Gregory W.; Fernandez, Mario R.; Yang, Chunying; Hitosugi, Taro; Cheng, Chia-Ho; Freischel, Audrey R.; Zhang, Ling; Li, Weimin; Hou, Hsinan; Schaub, Franz X.; Vedder, Alexis R.; Cen, Ling; McGraw, Kathy L.; Moon, Jungwon; Murphy, Daniel J.; Ballabio, Andrea; Kaufmann, Scott H.; Berglund, Anders E.; Cleveland, John L.
The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality (vol 51, pg 491.e1, 2019)
IMMUNITY
IF26.3
2020-01-0110
OAAI
Li, Chaofan; Zhu, Bibo; Son, Young Min; Wang, Zheng; Jiang, Li; Xiang, Min; Ye, Zhenqing; Beckermann, Kathryn E.; Wu, Yue; Jenkins, James W.; Siska, Peter J.; Vincent, Benjamin G.; Prakash, Y. S.; Peikert, Tobias; Edelson, Brian T.; Taneja, Reshma; Kaplan, Mark H.; Rathmell, Jeffrey C.; Dong, Haidong; Hitosugi, Taro; Sun, Jie

研究方向

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S
Sumin Kang
H 指数:34论文数:97被引数:6,259
T
Titus J. Boggon
H 指数:65论文数:269被引数:3.3万
F
Fadlo R. Khuri
H 指数:122论文数:1,089被引数:8.4万
J
Jing Chen
H 指数:35论文数:139被引数:6,187
范骏 封面图
范骏
H 指数:35论文数:126被引数:5,500
S
Sagar Lonial
H 指数:116论文数:1,510被引数:6.7万
W
Wilson I. Gonsalves
H 指数:54论文数:725被引数:1.0万
J
Jianxin Xie
H 指数:30论文数:77被引数:7,168
T
Tae‐Wook Chung
H 指数:35论文数:214被引数:5,550
S
Shannon Elf
H 指数:31论文数:126被引数:5,521