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收藏分享 收藏 分享 收藏 Chromatin-Based Cellular Dependency of HOXA9/MEIS1-Driven Acute Myeloid LeukemiaHOXA9/MEIS1驱动的急性髓系白血病的染色质依赖性
Valigi, Federica; Kucuktas, Fulya Mina; Fliamer, Ilya; Jevtic, Zivojin; Chatel-Soulet, Hughes-Etienne; Bovay, Amandine; Sivalingam, Rathick; Baosic, Andreja; Grebien, Florian; Slany, Robert K.; Tzankov, Alexandar; Juge, Sabine; Seguin, Jonathan; Wang, Menghan; El Taher, Athimed; Giorgetti, Luca; Schwaller, Juerg 分享 收藏 Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturationDembitz, Vilma; Lawson, Hannah; Burt, Richard; Natani, Sirisha; Philippe, Celine; James, Sophie C.; Atkinson, Samantha; Durko, Jozef; Wang, Lydia M.; Campos, Joana; Magee, Aoife M. S.; Woodley, Keith; Austin, Michael J.; Rio-Machin, Ana; Casado, Pedro; Bewicke-Copley, Findlay; Rodriguez Blanco, Giovanny; Pereira-Martins, Diego; Oudejans, Lieve; Boet, Emeline; von Kriegsheim, Alex; Schwaller, Juerg; Finch, Andrew J.; Patel, Bela; Sarry, Jean-Emmanuel; Tamburini, Jerome; Schuringa, Jan Jacob; Hazlehurst, Lori; Copland, John A., III; Yuneva, Mariia; Peck, Barrie; Cutillas, Pedro; Fitzgibbon, Jude; Rouault-Pierre, Kevin; Kranc, Kamil; Gallipoli, Paolo 分享 收藏 The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness programFagnan, Alexandre; Aid, Zakia; Baille, Marie; Drakul, Aneta; Robert, Elie; Lopez, Cecile K.; Thirant, Cecile; Lecluse, Yann; Riviere, Julie; Ignacimouttou, Cathy; Salmoiraghi, Silvia; Anguita, Eduardo; Naimo, Audrey; Marzac, Christophe; Pflumio, Francoise; Malinge, Sebastien; Wichmann, Christian; Huang, Yun; Lobry, Camille; Chaumeil, Julie; Soler, Eric; Bourquin, Jean-Pierre; Nerlov, Claus; Bernard, Olivier A.; Schwaller, Juerg; Mercher, Thomas 分享 收藏 The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemiaLawson, Hannah; Holt-Martyn, James P.; Dembitz, Vilma; Kabayama, Yuka; Wang, Lydia M.; Bellani, Aarushi; Atwal, Samanpreet; Saffoon, Nadia; Durko, Jozef; van de Lagemaat, Louie N.; De Pace, Azzura L.; Tumber, Anthony; Corner, Thomas; Salah, Eidarus; Arndt, Christine; Brewitz, Lennart; Bowen, Matthew; Dubusse, Louis; George, Derek; Allen, Lewis; Guitart, Amelie V.; Fung, Tsz Kan; So, Chi Wai Eric; Schwaller, Juerg; Gallipoli, Paolo; O'Carroll, Donal; Schofield, Christopher J.; Kranc, Kamil R. 分享 收藏 分享 收藏 ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansionBassani, Barbara; Simonetti, Giorgia; Cancila, Valeria; Fiorino, Antonio; Ciciarello, Marilena; Piva, Annamaria; Khorasani, Arman Mandegar; Chiodoni, Claudia; Lecis, Daniele; Gulino, Alessandro; Fonzi, Eugenio; Botti, Laura; Portararo, Paola; Costanza, Massimo; Brambilla, Marta; Colombo, Giorgia; Schwaller, Juerg; Tzankov, Alexandar; Ponzoni, Maurilio; Ciceri, Fabio; Bolli, Niccolo; Curti, Antonio; Tripodo, Claudio; Colombo, Mario P.; Sangaletti, Sabina 分享 收藏 Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemiaTubio-Santamaria, Nuria; Jayavelu, Ashok Kumar; Schnoeder, Tina M.; Eifert, Theresa; Hsu, Chen-Jen; Perner, Florian; Zhang, Qirui; Wenge, Daniela V.; Hansen, Fynn M.; Kirkpatrick, Joanna M.; Jyotsana, Nidhi; Lane, Steven W.; von Eyss, Bjoern; Deshpande, Aniruddha J.; Kuehn, Michael W. M.; Schwaller, Juerg; Cammann, Clemens; Seifert, Ulrike; Ebstein, Frederic; Krueger, Elke; Hochhaus, Andreas; Heuser, Michael; Ori, Alessandro; Mann, Matthias; Armstrong, Scott A.; Heidel, Florian H. 分享 收藏 分享 收藏 TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expressionTET2病变通过重新平衡GATA2表达增强CEBPA突变急性髓系白血病的侵袭性Heyes, Elizabeth; Wilhelmson, Anna S.; Wenzel, Anne; Manhart, Gabriele; Eder, Thomas; Schuster, Mikkel B.; Rzepa, Edwin; Pundhir, Sachin; DAltri, Teresa; Frank, Anne-Katrine; Gentil, Coline; Woessmann, Jakob; Schoof, Erwin M.; Meggendorfer, Manja; Schwaller, Jurg; Haferlach, Torsten; Grebien, Florian; Porse, Bo T. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from ChemotherapyForte, Dorian; Garcia-Fernandez, Maria; Sanchez-Aguilera, Abel; Stavropoulou, Vaia; Fielding, Claire; Martin-Perez, Daniel; Antonio Lopez, Juan; Costa, Ana S. H.; Tronci, Laura; Nikitopoulou, Efterpi; Barber, Michael; Gallipoli, Paolo; Marando, Ludovica; Fernandez de Castillejo, Carlos Lopez; Tzankov, Alexandar; Dietmann, Sabine; Cavo, Michele; Catani, Lucia; Curti, Antonio; Vazquez, Jesus; Frezza, Christian; Huntly, Brian J.; Schwaller, Juerg; Mendez-Ferrer, Simon 分享 收藏 Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia核相互作用集结构域蛋白1失活会损害GATA1-regulated红系分化并导致红白血病Leonards, Katharina; Almosailleakh, Marwa; Tauchmann, Samantha; Bagger, Frederik Otzen; Thirant, Cecile; Juge, Sabine; Bock, Thomas; Mereau, Helene; Bezerra, Matheus F.; Tzankov, Alexandar; Ivanek, Robert; Losson, Regine; Peters, Antoine H. F. M.; Mercher, Thomas; Schwaller, Juerg 分享 收藏 
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