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Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers Loi, Patrick; Schade, Amy E.; Rodriguez, Carrie L.; Krishnan, Anjana; Perurena, Naiara; Nguyen, Van T. M.; Xu, Yilin; Watanabe, Marina; Davis, Rachel A.; Gardner, Alycia; Pilla, Natalie F.; Mattioli, Kaia; Popow, Olesja; Gunduz, Nuray; Lannagan, Tamsin R. M.; Fitzgerald, Samantha; Sicinska, Ewa T.; Lin, Jia-Ren; Tan, William; Brais, Lauren K.; Haigis, Kevin M.; Giannakis, Marios; Ng, Kimmie; Santagata, Sandro; Helin, Kristian; Sansom, Owen J.; Cichowski, Karen 分享 收藏
SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis Tucker, Sarah A.; Hu, Song-Hua; Vyas, Sejal; Park, Albert; Joshi, Shakchhi; Inal, Aslihan; Lam, Tiffany; Tan, Emily; Haigis, Kevin M.; Haigis, Marcia C. 分享 收藏
Ala59 mutants of KRAS cooperate with Nf1 loss to enhance colon tumorigenesis Johnson, Christian William; Terrell, Elizabeth M.; Cook, Josh; Shui, Bing; O'Donoghue, Eve; Hull, Shannon; Yang, Moon Hee; Sheth, Shikha; Yaeger, Rona; Kopetz, Scott; Morrison, Deborah K.; Haigis, Kevin 分享 收藏
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Effects of KRAS Genetic Interactions on Outcomes in Cancers of the Lung, Pancreas, and Colorectum KRAS基因相互作用对肺癌、胰腺癌和结直肠癌预后的影响 Grabski, Isabella N.; Heymach, John V.; Kehl, Kenneth L.; Kopetz, Scott; Lau, Ken S.; Riely, Gregory J.; Schrag, Deborah; Yaeger, Rona; Irizarry, Rafael A.; Haigis, Kevin M. 分享 收藏
Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity Yang, Moon Hee; Tran, Timothy H.; Hunt, Bethany; Agnor, Rebecca; Johnson, Christian W.; Shui, Bing; Waybright, Timothy J.; Nowak, Jonathan A.; Stephen, Andrew G.; Simanshu, Dhirendra K.; Haigis, Kevin M. 分享 收藏
Oncogenic K-Ras suppresses global miRNA function Shui, Bing; Beyett, Tyler S.; Chen, Zhengyi; Li, Xiaoyi; Rocca, Gaspare La; Gazlay, William M.; Eck, Michael J.; Lau, Ken S.; Ventura, Andrea; Haigis, Kevin M. 分享 收藏
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GUK1 is a novel metabolic liability in oncogene-driven lung cancer Schneider, Jaime Laurel; Kurmi, Kiran; Dhiman, Ishita; Colapietro, Roberta; Joshi, Shakchhi; Johnson, Christian; Yoda, Satoshi; Paulo, Joao; Ruiz, Daniela; Stopka, Sylwia; Baquer, Gerard; Lin, Jessica; Haigis, Kevin; Agar, Nathalie; Gygi, Steven; Hata, Aaron; Haigis, Marcia 分享 收藏
Functional and biological heterogeneity of KRASQ61 mutations KRASQ61突变的功能和生物学异质性 Huynh, Minh, V; Hobbs, G. Aaron; Schaefer, Antje; Pierobon, Mariaelena; Carey, Leiah M.; Diehl, J. Nathaniel; DeLiberty, Jonathan M.; Thurman, Ryan D.; Cooke, Adelaide R.; Goodwin, Craig M.; Cook, Joshua H.; Lin, Lin; Waters, Andrew M.; Rashid, Naim U.; Petricoin, Emanuel F., III; Campbell, Sharon L.; Haigis, Kevin M.; Simeone, Diane M.; Lyssiotis, Costas A.; Cox, Adrienne D.; Der, Channing J. 分享 收藏
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Regulation of GTPase function by autophosphorylation Johnson, Christian W.; Seo, Hyuk-Soo; Terrell, Elizabeth M.; Yang, Moon-Hee; KleinJan, Fenneke; Gebregiworgis, Teklab; Gasmi-Seabrook, Genevieve M. C.; Geffken, Ezekiel A.; Lakhani, Jimit; Song, Kijun; Bashyal, Puspalata; Popow, Olesja; Paulo, Joao A.; Liu, Andrea; Mattos, Carla; Marshall, Christopher B.; Ikura, Mitsuhiko; Morrison, Deborah K.; Dhe-Paganon, Sirano; Haigis, Kevin M. 分享 收藏
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Regulation of RAS function by active site autophosphorylation Johnson, Christian; Seo, Hyuk-Soo; Terrell, Elizabeth; Geffken, Ezekiel; Lakhani, Jimit; Song, Kijun; Hagel, Kimberly; Popow, Olesja; Mattos, Carla; Morrison, Deborah; Dhe-Paganon, Sirano; Haigis, Kevin 分享 收藏
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