Buyun Tang

Sanofi

H指数:7

被引数:1,063

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A Comprehensive Discovery Platform for ELOVL1 Small Molecule Inhibitors Targeting Very Long Chain Fatty Acid Synthesis in Adrenoleukodystrophy

肾上腺脑白质营养不良中靶向极长链脂肪酸合成的ELOVL1小分子抑制剂的全面发现平台

Journal of Biological Chemistry

IF3.9

2026-05-060

OAAI

Elovl1 inhibition reduced very long chain fatty acids in a mouse model of adrenoleukodystrophy

Elovl1 抑制在肾上腺脑白质营养不良小鼠模型中减少了极长链脂肪酸

iScience

IF4.1

2025-07-310

Jeremy Y. Huang; Brian Freed; Martin Hanus; Kelly Keefe; Ming Sum Ruby Chiang; Alexander Brezzani; Yongyi Luo; Yihang Li; Becky Lam; Stephanie Holley; Joseph Gans; Zuzana Dostalova; Buyun Tang; Clifford Phaneuf; Erin Teeple; Laura Parisi; Lilu Guo; Zhonglin Zhao; Sofia N. Kinton; Jacquelyn Dwyer; Sandrine Teixeira; Hong Ma; Gary Asmussen; Rajashree McLaren; Donghui Wang; Ann Baker; Craig S. Siegel; David Fink; Kristen Randall; Alexei Belenky; Suchitra Venugopal; Giorgio Gaglia; Jennifer Johnson; Dinesh S. Bangari; Bailin Zhang; Alexander Michel; Jonathan D. Proto; Alla Kloss; S. Pablo Sardi; Tatiana Gladysheva; Can Kayatekin

An enzyme activity-based workflow for the identification and characterization of covalent inhibitors

一种基于酶活性的工作流程，用于共价抑制剂的鉴定和表征

SLAS Discovery

IF2.7

2025-07-180

PRE

Automation of multiplex biochemical assays to enhance productivity and reduce cycle time using a modular robotic platform

利用模块化机器人平台实现多重生物化学分析的自动化，以提高生产效率并缩短周期时间。

SLAS TECHNOLOGY

IF3.7

2024-12-010

OAAI

Brain glycogen serves as a critical glucosamine cache required for protein glycosylation

CELL METABOLISM

IF30.9

2021-07-0149

OAAI

Sun, Ramon C.; Young, Lyndsay E. A.; Bruntz, Ronald C.; Markussen, Kia H.; Zhou, Zhengqiu; Conroy, Lindsey R.; Hawkinson, Tara R.; Clarke, Harrison A.; Stanback, Alexandra E.; Macedo, Jessica K. A.; Emanuelle, Shane; Brewer, M. Kathryn; Rondon, Alberto L.; Mestas, Annette; Sanders, William C.; Mahalingan, Krishna K.; Tang, Buyun; Chikwana, Vimbai M.; Segvich, Dyann M.; Contreras, Christopher J.; Allenger, Elizabeth J.; Brainson, Christine F.; Johnson, Lance A.; Taylor, Richard E.; Armstrong, Dustin D.; Shaffer, Robert; Waechter, Charles J.; Vander Kooi, Craig W.; DePaoli-Roach, Anna A.; Roach, Peter J.; Hurley, Thomas D.; Drake, Richard R.; Gentry, Matthew S.

Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-03-0546