Tilman Schirmer - Publications, H-index & Citations

Tilman Schirmer

university of basel

60H指数

223论文数

1.3W被引数

收录论文 40

发表时间

Activation mechanism of the full-length histidine kinase LvrB from pathogenic Leptospira 致病性钩端螺旋体全长组氨酸激酶LvrB的激活机制

Nature Communications

IF15.7

2026-04-16

OAAI

Elia Agustoni; Ariel Mechaly; Joaquín Dalla Rizza; David Beriashvili; Kristyna Pluhackova; Polina Isaikina; Felipe Trajtenberg; Thomas Müntener; Elsio A. Wunder; Albert I. Ko; Tilman Schirmer; Alejandro Buschiazzo; Sebastian Hiller

Structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs

NATURE COMMUNICATIONS

IF15.7

2023-03-02

OAAI

Bruederlin, Mitchell; Boehm, Raphael; Fadel, Firas; Hiller, Sebastian; Schirmer, Tilman; Dubey, Badri N.

Mutant structure of metabolic switch protein in complex with monomeric c-di-GMP reveals a potential mechanism of protein-mediated ligand dimerization

SCIENTIFIC REPORTS

IF3.9

2023-02-21

OAAI

Dubey, Badri Nath; Shyp, Viktoriya; Fucile, Geoffrey; Sondermann, Holger; Jenal, Urs; Schirmer, Tilman

Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module

MICROORGANISMS

IF4.2

2021-07-31

OAAI

Schirmer, Tilman; de Beer, Tjaart A. P.; Tamegger, Stefanie; Harms, Alexander; Dietz, Nikolaus; Dranow, David M.; Edwards, Thomas E.; Myler, Peter J.; Phan, Isabelle; Dehio, Christoph

A Bacterial Inflammation Sensor Regulates c-di GMP Signaling, Adhesion, and Biofilm Formation

MBIO

IF4.7

2021-06-29

OAAI

Perkins, Arden; Tudorica, Dan A.; Teixeira, Raphael D.; Schirmer, Tilman; Zumwalt, Lindsay; Ogba, O. Maduka; Cassidy, C. Keith; Stansfeld, Phillip J.; Guillemin, Karen

Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase

NATURE COMMUNICATIONS

IF15.7

2021-04-12

OAAI

Teixeira, Raphael D.; Holzschuh, Fabian; Schirmer, Tilman

Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1)巴尔通体效应蛋白1 (Bep1) 选择性amp化Rac亚家族gtp酶的结构基础

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-15

OAAI

Dietz, Nikolaus; Huber, Markus; Sorg, Isabel; Goepfert, Arnaud; Harms, Alexander; Schirmer, Tilman; Dehio, Christoph

Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-07-01

OAAI

Hee, Chee-Seng; Habazettl, Judith; Schmutz, Christoph; Schirmer, Tilman; Jenal, Urs; Grzesiek, Stephan

Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter

NATURE COMMUNICATIONS

IF15.7

2020-02-10

OAAI

Kaczmarczyk, Andreas; Hempel, Antje M.; von Arx, Christoph; Bohm, Raphael; Dubey, Badri N.; Nesper, Jutta; Schirmer, Tilman; Hiller, Sebastian; Jenal, Urs

Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-12-27

OAAI

Dubey, Badri N.; Agustoni, Elia; Boehm, Raphael; Kaczmarczyk, Andreas; Mangia, Francesca; von Arx, Christoph; Jenal, Urs; Hiller, Sebastian; Plaza-Menacho, Ivan; Schirmer, Tilman

An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-03-18

OAAI

Stampfli, Anja R.; Goncharenko, Kristina V.; Meury, Marcel; Dubey, Badri N.; Schirmer, Tilman; Seebeck, Florian P.

Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators

ELIFE

IF0

2017-11-01

OAAI

Nesper, Jutta; Hug, Isabelle; Kato, Setsu; Hee, Chee-Seng; Habazetti, Judith Maria; Manfredi, Pablo; Grzesiek, Stephan; Schirmer, Tilman; Emonet, Thierry; Jenal, Urs

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking

SCIENCE ADVANCES

IF12.5

2016-09-02

OAAI

Dubey, Badri N.; Lori, Christian; Ozaki, Shogo; Fucile, Geoffrey; Plaza-Menacho, Ivan; Jenal, Urs; Schirmer, Tilman

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-01-19

OAAI

Stanger, Frederic V.; Burmann, Bjoern M.; Harms, Alexander; Aragao, Hugo; Mazur, Adam; Sharpe, Timothy; Dehio, Christoph; Hiller, Sebastian; Schirmer, Tilman

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

CELL REPORTS

IF6.9

2015-09-01

OAAI

Harms, Alexander; Stanger, Frederic Valentin; Scheu, Patrick Daniel; de Jong, Imke Greet; Goepfert, Arnaud; Glatter, Timo; Gerdes, Kenn; Schirmer, Tilman; Dehio, Christoph

Structural, Kinetic, and Docking Studies of Artificial imine Reductases Based on Biotin-Streptavidin Technology: An Induced Lock-and-Key Hypothesis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2014-10-28

PREAI

Munoz Robles, Victor; Duerrenberger, Marc; Heinisch, Tillmann; Lledos, Agusti; Schirmer, Tilman; Ward, Thomas R.; Marechal, Jean-Didier

Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-03-01

OAAI

Sundriyal, Amit; Massa, Claudia; Samoray, Dietrich; Zehender, Fabian; Sharpe, Timothy; Jenal, Urs; Schirmer, Tilman

A Dual Anchoring Strategy for the Localization and Activation of Artificial Metalloenzymes Based on the Biotin-Streptavidin Technology

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2013-04-02

OAAI

Zimbron, Jeremy M.; Heinisch, Tillmann; Schmid, Maurus; Hamels, Didier; Nogueira, Elisa S.; Schirmer, Tilman; Ward, Thomas R.

Human carbonic anhydrase II as host protein for the creation of artificial metalloenzymes: the asymmetric transfer hydrogenation of imines

CHEMICAL SCIENCE

IF7.4

2013-01-01

OAAI

Monnard, Fabien W.; Nogueira, Elisa S.; Heinisch, Tillmann; Schirmer, Tilman; Ward, Thomas R.

Oligomer Formation of the Bacterial Second Messenger c-di-GMP: Reaction Rates and Equilibrium Constants Indicate a Monomeric State at Physiological Concentrations

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2011-12-29

PREAI

Gentner, Martin; Allan, Martin G.; Zaehringer, Franziska; Schirmer, Tilman; Grzesiek, Stephan

研究方向