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Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy GCN2途径的离体激活代谢重编程T细胞,导致增强的过继细胞治疗 Paul, Michael St.; Saibil, Samuel D.; Kates, Meghan; Han, Seongjun; Lien, Scott C.; Laister, Rob C.; Hezaveh, Kebria; Kloetgen, Andreas; Penny, Susanne; Guo, Tingxi; Garcia-Batres, Carlos; Smith, Logan K.; Chung, Douglas C.; Elford, Alisha R.; Sayad, Azin; Pinto, Devanand; Mak, Tak W.; Hirano, Naoto; McGaha, Tracy; Ohashi, Pamela S. 分享 收藏
A large-scale, targeted metabolomics method for the analysis and quantification of metabolites in human plasma via liquid chromatography-mass spectrometry 通过液相色谱-质谱法分析和定量人血浆中代谢物的大规模,靶向代谢组学方法 McMillen, Teresa S.; Leslie, Andrew; Chisholm, Kenneth; Penny, Susanne; Gallant, Jeffrey; Cohen, Alejandro; Drucker, Arik; Fawcett, James P.; Pinto, Devanand M. 分享 收藏
Metabolome Changes With Diet-Induced Remission in Pediatric Crohn's Disease Ghiboub, Mohammed; Penny, Susanne; Verburgt, Charlotte M.; Boneh, Rotem Sigall; Wine, Eytan; Cohen, Alejandro; Dunn, Katherine A.; Pinto, Devanand M.; Benninga, Marc A.; de Jonge, Wouter J.; Levine, Arie; Van Limbergen, Johan E. 分享 收藏
Successful Dietary Therapy in Paediatric Crohn's Disease is Associated with Shifts in Bacterial Dysbiosis and Inflammatory Metabotype Towards Healthy Controls Verburgt, Charlotte M.; Dunn, Katherine A.; Ghiboub, Mohammed; Lewis, James D.; Wine, Eytan; Boneh, Rotem Sigall; Gerasimidis, Konstantinos; Shamir, Raanan; Penny, Susanne; Pinto, Devanand M.; Cohen, Alejandro; Bjorndahl, Paul; Svolos, Vaios; Bielawski, Joseph P.; Benninga, Marc A.; de Jonge, Wouter J.; Van Limbergen, Johan E. 分享 收藏
Proteomic analysis of plasma exosomes as biomarkers of response to MVP-S based immunotherapy Smith, Pascal; Teh, Evelyn; Chisholm, Ken; Penny, Susanne; Pinto, Devanand; Patterson, Kelcey; Dirk, Brennan; Bydoun, Moamen; Fiset, Stephan; Bramhecha, Yogesh; Hirsch, Heather; Hrytsenko, Olga; Graff, Jeremy 分享 收藏
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity 色氨酸衍生的微生物代谢物激活肿瘤相关巨噬细胞中的芳香烃受体以抑制抗肿瘤免疫 Hezaveh, Kebria; Shinde, Rahul S.; Kloetgen, Andreas; Halaby, Marie Jo; Lamorte, Sara; Ciudad, M. Teresa; Quevedo, Rene; Neufeld, Luke; Liu, Zhe Qi; Jin, Robbie; Grunwald, Barbara T.; Foerster, Elisabeth G.; Chaharlangi, Danica; Guo, Mengdi; Makhijani, Priya; Zhang, Xin; Pugh, Trevor J.; Pinto, Devanand M.; Co, Ileana L.; McGuigan, Alison P.; Jang, Gun Ho; Khokha, Rama; Ohashi, Pamela S.; O'Kane, Grainne M.; Gallinger, Steven; Navarre, William W.; Maughan, Heather; Philpott, Dana J.; Brooks, David G.; McGaha, Tracy L. 分享 收藏
Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis Dahn, Margaret L.; Walsh, Hayley R.; Dean, Cheryl A.; Giacomantonio, Michael A.; Fernando, Wasundara; Murphy, J. Patrick; Walker, Olivia L.; Wasson, Marie-Claire D.; Gujar, Shashi; Pinto, Devanand M.; Marcato, Paola 分享 收藏
Coenzyme A fuels T cell anti-tumor immunity St Paul, Michael; Saibil, Samuel D.; Han, SeongJun; Israni-Winger, Kavita; Lien, Scott C.; Laister, Rob C.; Sayad, Azin; Penny, Susanne; Amaria, Rodabe N.; Haydu, Lauren E.; Garcia-Batres, Carlos R.; Kates, Meghan; Mulder, David T.; Robert-Tissot, Celine; Gold, Matthew J.; Tran, Charles W.; Elford, Alisha R.; Nguyen, Linh T.; Pugh, Trevor J.; Pinto, Devanand M.; Wargo, Jennifer A.; Ohashi, Pamela S. 分享 收藏
Heat stress response in the closest algal relatives of land plants reveals conserved stress signaling circuits de Vries, Jan; de Vries, Sophie; Curtis, Bruce A.; Zhou, Hong; Penny, Susanne; Feussner, Kirstin; Pinto, Devanand M.; Steinert, Michael; Cohen, Alejandro M.; Schwartzenberg, Klaus; Archibald, John M. 分享 收藏
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