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收藏分享 收藏 分享 收藏 PTEN deficiency induces an extrahepatic cholangitis-cholangiocarcinoma continuum via aurora kinase A in mice
Yang, Yan; Wang, Jiale; Wan, Jianhua; Cheng, Qianqian; Cheng, Zenong; Zhou, Xueli; Wang, Oliver; Shi, Kelvin; Wang, Lingxiang; Wang, Bin; Zhu, Xiaohui; Chen, Jiaxiang; Feng, Dongfeng; Liu, Yang; Jahan-mihan, Yasmin; Haddock, Ashley N.; Edenfield, Brandy H.; Peng, Guang; Hohenstein, Jessica D.; Mccabe, Chantal E.; O'Brien, Daniel R.; Wang, Chen; Ilyas, Sumera I.; Jiang, Liuyan; Torbenson, Michael S.; Wang, Huamin; Nakhleh, Raouf E.; Shi, Xuemei; Wang, Ying; Bi, Yan; Gores, Gregory J.; Patel, Tushar; Ji, Baoan 分享 收藏 GRB2 stabilizes RAD51 at reversed replication forks restricting genomic instability and associated innate immune responseAhmed, Zamal; Ye, Zu; Xu, Shengfeng; Shi, Yin; Cheng, Xueqian; Zhang, Yuan; Roy, Sunetra; Namjoshi, Sarita; Longo, Michael A.; Link, Todd; Schlacher, Katharina; Peng, Guang; Yu, Dihua; Wang, Bin; Tainer, John 分享 收藏 PRMT blockade induces defective DNA replication stress response via ATR suppression and synergizes with PARP inhibitionBisht, Deepa; Li, Yang; Dobrolecki, Lacey E.; Sallas, Christina; Zhang, Xudong; Kerr, Travis D.; Wang, Yalong; Awasthi, Sharad; Kaundal, Babita; Wu, Siqi; Peng, Weiyi; Mendillo, Marc L.; Lu, Yiling; Jeter, Collene R.; Peng, Guang; Liu, Jinsong; Westin, Shannon N.; Sood, Anil K.; Lewis, Michael T.; Das, Jishnu; Yi, S. Stephen; Bedford, Mark T.; McGrail, Daniel J.; Sahni, Nidhi 分享 收藏 GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancerYe, Zu; Xu, Shengfeng; Shi, Yin; Cheng, Xueqian; Zhang, Yuan; Roy, Sunetra; Namjoshi, Sarita; Longo, Michael A.; Link, Todd M.; Schlacher, Katharina; Peng, Guang; Yu, Dihua; Wang, Bin; Tainer, John A.; Ahmed, Zamal 分享 收藏 分享 收藏 PRMT blockade induces defective DNA replication stress response and with PARP inhibitionLi, Yang; Dobrolecki, Lacey E.; Sallas, Christina; Zhang, Xudong; Kerr, Travis D.; Bisht, Deepa; Wang, Yalong; Awasthi, Sharad; Kaundal, Babita; Wu, Siqi; Peng, Weiyi; Mendillo, Marc L.; Lu, Yiling; Jeter, Collene R.; Peng, Guang; Liu, Jinsong; Westin, Shannon N.; Sood, Anil K.; Lewis, Michael T.; Das, Jishnu; Yi, S. Stephen; Bedford, Mark T.; Mcgrill, Daniel J.; Sahni, Nidhi 分享 收藏 Targeting polyploid giant cancer cells potentiates a therapeutic response and overcomes resistance to PARP inhibitors in ovarian cancerZhang, Xudong; Yao, Jun; Li, Xiaoran; Niu, Na; Liu, Yan; Hajek, Richard A.; Peng, Guang; Westin, Shannon; Sood, Anil K.; Liu, Jinsong 分享 收藏 分享 收藏 SETD2 loss and ATR inhibition synergistically promote cGAS signaling and immunotherapy response in renal cell carcinomaLiu, Xiande; Zhang, Yanting; Zhang, Xuesong; McGrail, Daniel; Lam, Truong; Hoang, Anh; Hasanov, Elshad; Manyam, Ganiraju; Peterson, Christine B.; Zhu, Haifeng; Kumar, Shwetha V.; Akbani, Rehan; Tannir, Nizar M.; Peng, Guang; Jonasch, Eric 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy9p21丢失赋予冷肿瘤免疫微环境和对免疫检查点治疗的原发性抗性Han, Guangchun; Yang, Guoliang; Hao, Dapeng; Lu, Yang; Thein, Kyaw; Simpson, Benjamin S.; Chen, Jianfeng; Sun, Ryan; Alhalabi, Omar; Wang, Ruiping; Dang, Minghao; Dai, Enyu; Zhang, Shaojun; Nie, Fengqi; Zhao, Shuangtao; Guo, Charles; Hamza, Ameer; Czerniak, Bogdan; Cheng, Chao; Siefker-Radtke, Arlene; Bhat, Krishna; Futreal, Andrew; Peng, Guang; Wargo, Jennifer; Peng, Weiyi; Kadara, Humam; Ajani, Jaffer; Swanton, Charles; Litchfield, Kevin; Ahnert, Jordi Rodon; Gao, Jianjun; Wang, Linghua 分享 收藏 GRB2 enforces homology-directed repair initiation by MRE11GRB2通过MRE11强制同源定向修复启动Ye, Zu; Xu, Shengfeng; Shi, Yin; Bacolla, Albino; Syed, Aleem; Moiani, Davide; Tsai, Chi-Lin; Shen, Qiang; Peng, Guang; Leonard, Paul G.; Jones, Darin E.; Wang, Bin; Tainer, John A.; Ahmed, Zamal 分享 收藏 MEK Inhibition Remodels the Immune Landscape of Mutant KRAS Tumors to Overcome Resistance to PARP and Immune Checkpoint InhibitorsYang, Bin; Li, Xi; Fu, Yu; Guo, Ensong; Ye, Youqiong; Li, Fuxia; Liu, Si; Xiao, Rourou; Liu, Chen; Lu, Funian; Huang, Jia; Qin, Tianyu; Han, Leng; Peng, Guang; Mills, Gordon B.; Sun, Chaoyang; Chen, Gang 分享 收藏 Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma转移性胃腺癌中肿瘤内异质性和谱系多样性的单细胞解剖Wang, Ruiping; Dang, Minghao; Harada, Kazuto; Han, Guangchun; Wang, Fang; Pool Pizzi, Melissa; Zhao, Meina; Tatlonghari, Ghia; Zhang, Shaojun; Hao, Dapeng; Lu, Yang; Zhao, Shuangtao; Badgwell, Brian D.; Blum Murphy, Mariela; Shanbhag, Namita; Estrella, Jeannelyn S.; Roy-Chowdhuri, Sinchita; Abdelhakeem, Ahmed Adel Fouad; Wang, Yuanxin; Peng, Guang; Hanash, Samir; Calin, George A.; Song, Xingzhi; Chu, Yanshuo; Zhang, Jianhua; Li, Mingyao; Chen, Ken; Lazar, Alexander J.; Futreal, Andrew; Song, Shumei; Ajani, Jaffer A.; Wang, Linghua 分享 收藏 
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