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B

Bahram Valamehr

fate therapeutics, inc.
H指数:28
被引数:3,326

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Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease

炎症小体抗性iPSC来源的髓源抑制细胞可减轻异种移植物抗宿主病

Blood
IF23.1
2025-07-250
PRE
Lie Ma; Brent Koehn; Michael Zaiken; Keli L. Hippen; Kyle Smith; Jeremy Allred; Robin Williams; Ke Yao; Jordan Fink; Asim Saha; Benjamin Koop; Nathaniel Payne; Renata Widelak; Angela Panoskaltsis-Mortari; Megan J. Riddle; Jakub Tolar; Cindy Eide; Lily Xia; Alec D. Witty; Amit K. Mehta; Matthew Denholtz; Mehrdad Hefazi; Sophia Hani; Saad S. Kenderian; Jeffrey S. Miller; Jeffrey J. Molldrem; Leslie S. Kean; Bahram Valamehr; Bruce R. Blazar
Off-the-shelf induced pluripotent stem-cell-derived natural killer-cell therapy in relapsed or refractory B-cell lymphoma: a multicentre, open-label, phase 1 study

现成型诱导多能干细胞来源的自然杀伤细胞疗法在复发或难治性B细胞淋巴瘤中的应用：一项多中心、开放标签、I期研究

lancet haematology
IF0
2025-07-010
PRE
Paolo Strati; Januario Castro; Aaron Goodman; Veronika Bachanova; Manali Kamdar; Farrukh T Awan; Scott R Solomon; Lilly Wong; Carol Wong; Deepa Patel; Cara Bickers; Wei Zhao; Zahid Bashir; Bahram Valamehr; Rebecca L Elstrom; Krish Patel
iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors

iPSC来源的三模态T细胞（通过CAR、TCR和hnCD16模态工程化改造）能够克服异质性肿瘤中的抗原逃逸。

Cell Reports Medicine
IF10.6
2025-06-190
OAAI
Bi-Huei Yang; Alma Gutierrez; Angela Liao; Soheila Shirinbak; Bjoern Gaertner; Mochtar Pribadi; Hui-Yi Chu; Pei-Fang Tsai; Yu-Sheng Eason Lin; David Gonzalez; Wen-I Yeh; Chia-Wei Chang; Ryan Bjordahl; Tom Lee; Martin Hosking; Eigen Peralta; Bahram Valamehr
Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy

iPSC来源的CAR T细胞通过工程化改造克服多种实体瘤疗效障碍，实现对HER2的偏好性肿瘤靶向。

Cell Stem Cell
IF20.4
2025-06-040
PRE
Martin P. Hosking; Soheila Shirinbak; Kyla Omilusik; Shilpi Chandra; Mika K. Kaneko; Angela Gentile; Susumu Yamamoto; Bishwas Shrestha; Joy Grant; Megan Boyett; Demetrio Cardenas; Hannah Keegan; Samad Ibitokou; Carolina Pavon; Takahiro Mizoguchi; Tatsuya Ihara; Daisuke Nakayama; Ramzey Abujarour; Tom T. Lee; Raedun Clarke; Jode Goodridge; Eigen Peralta; Tatsuo Maeda; Junichi Takagi; Takao Arimori; Yukinari Kato; Bahram Valamehr
A novel CD3ε fusion receptor allows T cell engager use in TCR-less allogeneic CAR T cells to improve activity and prevent antigen escape

一种新型的CD3ε融合受体允许在无TCR的同种异体CAR T细胞中使用T细胞连接器，以提高活性并防止抗原逃逸。

Molecular Therapy
IF12
2025-05-280
PRE
Dan Lu; Hui-Yi Chu; Soo Park; Mark Landon; Masanao Tsuda; Earl Avramis; Carissa Dege; Thomas Dailey; Yijia Pan; Sandeep Kothapally Hanok; Matthew Denholtz; Ramzey Abujarour; Tom Lee; John Goulding; Martin Hosking; Jodie Goodridge; Eigen Peralta; Bahram Valamehr
Alloimmune Defense Receptor Combined with Genetic Ablation of Adhesion Ligand CD58 Is a Comprehensive Approach to Promote Functional Persistence of Allogeneic Cell Therapies without Conditioning Chemotherapy

同种免疫防御受体与粘附配体CD58的遗传剔除相结合是一种促进异基因细胞疗法功能持久性的综合方法，无需条件性化疗。

BLOOD
IF23.1
2024-11-050
PRE
Williams, Alan; Mbofung, Rina; Morales-Mantilla, Daniel; Groff, Brian; O'Connor, Alison; Li, Binzhong; Janani, Ramesh; Rezner, Betsy; Jelcic, Mark; Pan, Yijia; Lee, Tom; Malmberg, Karl-Johan; Mamonkin, Maksim; Goulding, John; Goodridge, Jode; Valamehr, Bahram
CXCR4 has a dual role in improving the efficacy of BCMA-redirected CAR-NK cells in multiple myeloma

CXCR4在改善BCMA重定向的car-nk细胞在多发性骨髓瘤中的疗效方面具有双重作用

FRONTIERS IN IMMUNOLOGY
IF5.9
2024-06-241
OAAI
Moles, Michael W.; Erdlei, Henry; Menzel, Lutz; Massaro, Marialucia; Fiori, Agnese; Bunse, Mario; Schrimpf, Moritz; Gerlach, Kerstin; Gudipati, Venugopal; Reiser, John; Mathavan, Ketan; Goodrich, Jodie P.; Huppa, Johannes B.; Kroenke, Jan; Valamehr, Bahram; Hoepken, Uta E.; Rehm, Armin
High-avidity BCMA CAR and high- affinity, non-cleavable CD16 Fc receptor incorporated in off-the-shelf CAR T cells promote multi-antigen targeting and durable anti-tumor cytotoxicity in the treatment of multiple myeloma
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Reiser, John; O'Connor, Alison; Hancock, Bryan; Markov, Spas; Groff, Brian; Gutierrez, Alma; Meza, Miguel; Jelcik, Mark; Pan, Yijia; Garcia, Alex; Goulding, Bobby; Denholtz, Matthew; Lee, Tom; Abujarour, Ramzey; Bjordahl, Ryan; Rehm, Armin; Clarke, Raedun; Goodridge, Jode; Valamehr, Bahram
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells (vol 6, pg 1284, 2022)
NATURE BIOMEDICAL ENGINEERING
IF26.6
2024-02-120
OA
van der Stegen, Sjoukje J. C.; Lindenbergh, Pieter L.; Petrovic, Roseanna M.; Xie, Hongyao; Diop, Mame P.; Alexeeva, Vera; Shi, Yuzhe; Mansilla-Soto, Jorge; Hamieh, Mohamad; Eyquem, Justin; Cabriolu, Annalisa; Wang, Xiuyan; Abujarour, Ramzey; Lee, Tom; Clarke, Raedun; Valamehr, Bahram; Themeli, Maria; Riviere, Isabelle; Sadelain, Michel
A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors
MED
IF11.8
2023-07-0110
OA
Goulding, John; Yeh, Wen-, I; Hancock, Bryan; Blum, Robert; Xu, Tianhao; Yang, Bi-Huei; Chang, Chia-Wei; Groff, Brian; Avramis, Earl; Pribadi, Mochtar; Pan, Yijia; Chu, Hui-Yi; Sikaroodi, Shohreh; Fong, Lauren; Brookhouser, Nicholas; Dailey, Thomas; Meza, Miguel; Denholtz, Matthew; Diaz, Evelyn; Martin, Judy; Szabo, Peter; Cooley, Sarah; de Andrade, Lucas Ferrari; Lee, Tom T.; Bjordahl, Ryan; Wucherpfennig, Kai W.; Valamehr, Bahram
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
NATURE COMMUNICATIONS
IF15.7
2022-11-2938
OAAI
Cichocki, Frank; Bjordahl, Ryan; Goodridge, Jodie P.; Mahmood, Sajid; Gaidarova, Svetlana; Abujarour, Ramzey; Davis, Zachary B.; Merino, Aimee; Tuininga, Katie; Wang, Hongbo; Kumar, Akhilesh; Groff, Brian; Witty, Alec; Bonello, Greg; Huffman, Janel; Dailey, Thomas; Lee, Tom T.; Malmberg, Karl-Johan; Walcheck, Bruce; Hoepken, Uta; Rehm, Armin; Valamehr, Bahram; Miller, Jeffrey S.
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-11-0120
OAAI
Haroun-Izquierdo, Alvaro; Vincenti, Marianna; Netskar, Herman; van Ooijen, Hanna; Zhang, Bin; Bendzick, Laura; Kanaya, Minoru; Momayyezi, Pouria; Li, Shuo; Wiiger, Merete Thune; Hoel, Hanna Julie; Krokeide, Silje Zandstra; Kremer, Veronika; Tjonnfjord, Geir; Berggren, Stephanie; Wikstroem, Kristina; Blomberg, Pontus; Alici, Evren; Felices, Martin; oenfelt, Bjoern; Hoeglund, Petter; Valamehr, Bahram; Ljunggren, Hans-Gustaf; Bjoerklund, Andreas; Hammer, Quirin; Kveberg, Lise; Cichocki, Frank; Miller, Jeffrey S.; Malmberg, Karl-Johan; Sohlberg, Ebba
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells
NATURE BIOMEDICAL ENGINEERING
IF26.6
2022-08-0847
OA
van der Stegen, Sjoukje J. C.; Lindenbergh, Pieter L.; Petrovic, Roseanna M.; Xie, Hongyao; Diop, Mame P.; Alexeeva, Vera; Shi, Yuzhe; Mansilla-Soto, Jorge; Hamieh, Mohamad; Eyquem, Justin; Cabriolu, Annalisa; Wang, Xiuyan; Abujarour, Ramzey; Lee, Tom; Clarke, Raedun; Valamehr, Bahram; Themeli, Maria; Riviere, Isabelle; Sadelain, Michel

研究方向

暂未获取到该数据
R
Ramzey Abujarour
H 指数:20论文数:67被引数:3,397
R
Ryan Bjordahl
H 指数:18论文数:86被引数:1,647
J
Jeffrey S. Miller
H 指数:113论文数:1,108被引数:4.6万
T
Tom Lee
H 指数:36论文数:291被引数:5,678
F
Frank Cichocki
H 指数:34论文数:147被引数:4,634
S
Svetlana Gaidarova
H 指数:23论文数:66被引数:3,691
R
Raedun Clarke
H 指数:11论文数:45被引数:871
T
Tom T. Lee
H 指数:12论文数:27被引数:1,016
B
Bruce Walcheck
H 指数:43论文数:155被引数:6,341
B
Brian Groff
H 指数:9论文数:55被引数:436