Hashim M. Al‐Hashimi - Publications, H-index & Citations

Hashim M. Al‐Hashimi

Columbia University

61H指数

264论文数

1.2W被引数

收录论文 121

发表时间

Assessing the contribution of rare DNA states to cancer mutational signatures using sequence-specific conformational fingerprinting 评估罕见DNA状态对癌症突变特征的贡献：基于序列特异性构象指纹图谱

Nature Communications

IF15.7

2026-04-23

OAAI

Or Szekely; Yeongjoon Lee; Atul K. Rangadurai; Serafima Guseva; Joshua Cooksey; Edgar M. Faison; Nikita Zalenski; Qi Zhang; Zucai Suo; Hashim M. Al-Hashimi

Revealing hidden protonated conformational states in RNA dynamic ensembles 揭示RNA动态体系中隐藏的质子化构象状态

NUCLEIC ACIDS RESEARCH

IF13.1

2025-12-11

PREAI

Geng, Ainan; Roy, Rohit; Ganser, Laura; Li, Linshu; Al-Hashimi, Hashim M.

An A-T Hoogsteen Base Pair in a Naked DNA Hairpin Motif: A Protein-Recognized Conformation 裸DNA发夹结构中的A-T Hoogsteen碱基对：一种被蛋白质识别的构象

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2025-04-26

PREAI

Guseva, Serafima; Szekely, Or; Geng, Ainan; Smith, Kai; Pratihar, Supriya; Lee, Yeongjoon; Li, Linshu; Korn, Sophie M.; Gu, Stephanie; Al-Hashimi, Hashim M.

Conformational penalties: New insights into nucleic acid recognition 构象惩罚: 核酸识别的新见解

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-12-01

PREAI

Geng, Ainan; Roy, Rohit; Al-Hashimi, Hashim M.

Exploring the energetic and conformational properties of the sequence space connecting naturally occurring RNA tetraloop receptor motifs 探索连接天然存在的RNA四环受体基序的序列空间的能量和构象特性

RNA

IF5

2024-10-03

OAAI

Shin, John H.; Cuevas, Lena M.; Roy, Rohit; Bonilla, Steve L.; Al-Hashimi, Hashim; Greenleaf, William J.; Herschlag, Daniel

AlphaFold3 takes a step toward decoding molecular behavior and biological computation

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-07-08

PREAI

Roy, Rohit; Al-Hashimi, Hashim M.

NMR measurements of transient low-populated tautomeric and anionic Watson-Crick-like GT/U in RNA:DNA hybrids: implications for the fidelity of transcription and CRISPR/Cas9 gene editing

NUCLEIC ACIDS RESEARCH

IF13.1

2024-01-28

OAAI

Szekely, Or; Rangadurai, Atul Kaushik; Gu, Stephanie; Manghrani, Akanksha; Guseva, Serafima; Al-Hashimi, Hashim M.

An RNA excited conformational state at atomic resolution

NATURE COMMUNICATIONS

IF15.7

2023-12-19

OAAI

Geng, Ainan; Ganser, Laura; Roy, Rohit; Shi, Honglue; Pratihar, Supriya; Case, David A.; Al-Hashimi, Hashim M.

Hydrogen bonding in duplex DNA probed by DNP enhanced solid-state NMR N-H bond length measurements 通过DNP增强的固态NMR n-h键长测量探测双链体DNA中的氢键

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-12-04

OAAI

Bhai, Lakshmi; Thomas, Justin K.; Conroy, Daniel W.; Xu, Yu; Al-Hashimi, Hashim M.; Jaroniec, Christopher P.

Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-10-13

OAAI

Roy, Rohit; Geng, Ainan; Shi, Honglue; Merriman, Dawn K.; Dethoff, Elizabeth A.; Salmon, Loic; Al-Hashimi, Hashim M.

Turing, von Neumann, and the computational architecture of biological machines

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-06-12

OAAI

Al-Hashimi, Hashim M.

Dynamic basis for dA○dGTP and dA○d8OGTP misincorporation via Hoogsteen base pairs

NATURE CHEMICAL BIOLOGY

IF13.7

2023-04-24

OAAI

Gu, Stephanie; Szymanski, Eric S.; Rangadurai, Atul K.; Shi, Honglue; Liu, Bei; Manghrani, Akanksha; Al-Hashimi, Hashim M.

mRNA-induced conformational changes control MYC protein complex assembly

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-01

OAAI

Mayr, Christine; Luo, Yang; Pratihat, Supriya; Horste, Ellen; Al-Hashimi, Hashim

RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs

CELL REPORTS

IF6.9

2022-08-01

OAAI

Choi, Seung H.; Flamand, Mathieu N.; Liu, Bei; Zhu, Huanyu; Hu, Meghan; Wang, Melanie; Sewell, Jonathon; Holley, Christopher L.; Al-Hashimi, Hashim M.; Meyer, Kate D.

Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy 使用动态核极化固态NMR光谱探测双链DNA中的watson-crick和Hoogsteen碱基配对

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-20

OAAI

Conroy, Daniel W.; Xu, Yu; Shi, Honglue; Salguero, Nicole Gonzalez; Purusottam, Rudra N.; Shannon, Matthew D.; Al-Hashimi, Hashim M.; Jaroniec, Christopher P.

Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-06-07

OAAI

Rangadurai, Atul; Shi, Honglue; Xu, Yu; Liu, Bei; Abou Assi, Hala; Boom, John D.; Zhou, Huiqing; Kimsey, Isaac J.; Al-Hashimi, Hashim M.

Structural basis for impaired 5′ processing of a mutant tRNA associated with defects in neuronal homeostasis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-01

OAAI

Lai, Lien B.; Lai, Stella M.; Szymanski, Eric S.; Kapur, Mridu; Choi, Edric K.; Al-Hashimi, Hashim M.; Ackerman, Susan L.; Gopalan, Venkat

Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA

NUCLEIC ACIDS RESEARCH

IF13.1

2021-11-18

OAAI

Shi, Honglue; Kimsey, Isaac J.; Gu, Stephanie; Liu, Hsuan-Fu; Pham, Uyen; Schumacher, Maria A.; Al-Hashimi, Hashim M.

Developments in solution-state NMR yield broader and deeper views of the dynamic ensembles of nucleic acids

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2021-10-01

OAAI

Liu, Bei; Shi, Honglue; Al-Hashimi, Hashim M.

A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions 定量模型预测m6A如何重塑核酸杂交和构象转变的动力学格局

NATURE COMMUNICATIONS

IF15.7

2021-08-31

OAAI

Liu, Bei; Shi, Honglue; Rangadurai, Atul; Nussbaumer, Felix; Chu, Chia-Chieh; Erharter, Kevin Andreas; Case, David A.; Kreutz, Christoph; Al-Hashimi, Hashim M.

研究方向