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L

Leila Dorling

University of Cambridge
H指数:21
被引数:2,164

个人简介

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教育背景

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工作经历

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荣誉奖项

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Genetic and cellular architecture of breast cancer risk across ancestries

不同人种乳腺癌风险的遗传和细胞结构

JNCI Cancer Spectrum
IF4.1
2026-09-280
OA
James L Li, PhD; Maria Zanti, PhD; Jacob Williams, PhD; Om Jahagirdar, MSc; Guochong Jia, PhD, MPH; Alistair Turcan, BS; Qiang Hu, PhD; Jean-Tristan Brandenburg, PhD; Li Yan, PhD; Weang-Kee Ho, PhD; Jingmei Li, PhD; José Patricio Miranda, BS; Devika Godbole, MSc; Julie-Alexia Dias, PhD; Xiaomeng Zhang, PhD; Leila Dorling, PhD; Wenlong Carl Chen, PhD; Nicholas Boddicker, PhD; Ying Wang, PhD; Alicia Martin, PhD; Yan Dora Zhang, PhD; Joe Dennis, MSc; Esther M John, PhD, MSPH; Gabriela Torres-Mejia, MD, PhD; Lawrence H Kushi, ScD; Jeffrey Weitzel, MD; Susan L Neuhausen, PhD; Luis Carvajal-Carmona, PhD; Christopher Haiman, ScD; Elad Ziv, MD; Laura Fejerman, PhD, MSc; Wei Zheng, MD, PhD, MPH; Dezheng Huo, MD, PhD; Douglas Easton, PhD; Stephen J Chanock, MD; Nilanjan Chatterjee, PhD; Peter Kraft, PhD; Montserrat Garcia-Closas, MD, DrPh; Wendy S W Wong, PhD; Kyriaki Michailidou, PhD; Qianqian Zhu, PhD; Martin Jinye Zhang, PhD; Diptavo Dutta, PhD; Thomas U Ahearn, PhD, MPH; Haoyu Zhang, PhD; null
Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types

大规模的全基因组关联研究揭示了与癌症类型中辐射诱导的急性毒性相关的常见遗传因素

JNCI CANCER SPECTRUM
IF4.1
2023-10-203
OAAI
Naderi, Elnaz; Aguado-Barrera, Miguel E.; Schack, Line M. H.; Dorling, Leila; Rattay, Tim; Fachal, Laura; Summersgill, Holly; Martinez-Calvo, Laura; Welsh, Ceilidh; Dudding, Tom; Odding, Yasmin; Varela-Pazos, Ana; Jena, Rajesh; Thomson, David J.; Steenbakkers, Roel J. H. M.; Dennis, Joe; Lobato-Busto, Ramon; Alsner, Jan; Ness, Andy; Nutting, Chris; Gomez-Caamano, Antonio; Eriksen, Jesper G.; Thomas, Steve J.; Bates, Amy M.; Webb, Adam J.; Choudhury, Ananya; Rosenstein, Barry S.; Taboada-Valladares, Begona; Herskind, Carsten; Azria, David; Dearnaley, David P.; de Ruysscher, Dirk; Sperk, Elena; Hall, Emma; Stobart, Hilary; Chang-Claude, Jenny; De Ruyck, Kim; Veldeman, Liv; Altabas, Manuel; De Santis, Maria Carmen; Farcy-Jacquet, Marie-Pierre; Veldwijk, Marlon R.; Sydes, Matthew R.; Parliament, Matthew; Usmani, Nawaid; Burnet, Neil G.; Seibold, Petra; Symonds, R. Paul; Elliott, Rebecca M.; Bultijnck, Renee; Gutierrez-Enriquez, Sara; Molla, Meritxell; Gulliford, Sarah L.; Green, Sheryl; Rancati, Tiziana; Reyes, Victoria; Carballo, Ana; Peleteiro, Paula; Sosa-Fajardo, Paloma; Parker, Chris; Fonteyne, Valerie; Johnson, Kerstie; Lambrecht, Maarten; Vanneste, Ben; Valdagni, Riccardo; Giraldo, Alexandra; Ramos, Monica; Diergaarde, Brenda; Liu, Geoffrey; Leal, Suzanne M.; Chua, Melvin L. K.; Pring, Miranda; Overgaard, Jens; Cascallar-Caneda, Luis M.; Duprez, Frederic; Talbot, Christopher J.; Barnett, Gillian C.; Dunning, Alison M.; Vega, Ana; Andreassen, Christian Nicolaj; Langendijk, Johannes A.; West, Catharine M. L.; Alizadeh, Behrooz Z.; Kerns, Sarah L.
Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer

Meta-gis确定头颈癌急性辐射诱发毒性的遗传力

RADIOTHERAPY AND ONCOLOGY
IF5.3
2022-11-014
OAAI
Naderi, Elnaz; Schack, Line M. H.; Welsh, Ceilidh; Sim, Adelene Y. L.; Aguado-Barrera, Miguel E.; Dudding, Tom; Summersgil, Holly; Martinez-Calvo, Laura; Ong, Enya H. W.; Odding, Yasmin; Varela-Pazos, Ana; Steenbakkers, Roel J. H. M.; Crijns, Anne P. G.; Jena, Rajesh; Pring, Miranda; Dennis, Joe; Lobato-Busto, Ramon; Alsner, Jan; Ness, Andy; Nutting, Christopher; Thomson, David J.; Gomez-Caamano, Antonio; Eriksen, Jesper G.; Thomas, Steve J.; Bates, Amy M.; Overgaard, Jens; Cascallar-Caneda, Luis M.; Duprez, Frederic; Barnett, Gillian C.; Dorling, Leila; Chua, Melvin L. K.; Vega, Ana; West, Catharine M. L.; Langendijk, Johannes A.; Andreassen, Christian Nicolaj; Alizadeh, Behrooz Z.
No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
2022-11-013
OAAI
Barnett, Gillian C.; Kerns, Sarah L.; Dorling, Leila; Fachal, Laura; Aguado-Barrera, Miguel E.; Martinez-Calvo, Laura; Jandu, Harkeran K.; Welsh, Ceilidh; Tyrer, Jonathan; Coles, Charlotte E.; Haviland, Joanne S.; Parker, Christopher; Gomez-Caamano, Antonio; Calvo-Crespo, Patricia; Sosa-Fajardo, Paloma; Burnet, Neil G.; Summersgill, Holly; Webb, Adam; De Ruysscher, Dirk; Seibold, Petra; Chang-Claude, Jenny; Talbot, Christopher J.; Rattay, Tim; Parliament, Matthew; De Ruyck, Kim; Rosenstein, Barry S.; Pharoah, Paul D. P.; Dunning, Alison M.; Vega, Ana; West, Catharine M. L.
Segregation analysis of 17,425 population-based breast cancer families: Evidence for genetic susceptibility and risk prediction
AMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
2022-10-0115
OAAI
Li, Shuai; MacInnis, Robert J.; Lee, Andrew; Nguyen-Dumont, Tu; Dorling, Leila; Carvalho, Sara; Dite, Gillian S.; Shah, Mitul; Luccarini, Craig; Wang, Qin; Milne, Roger L.; Jenkins, Mark A.; Giles, Graham G.; Dunning, Alison M.; Pharoah, Paul D. P.; Southey, Melissa C.; Easton, Douglas F.; Hopper, John L.; Antoniou, Antonis C.
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study

BOADICEA多因素乳腺癌风险预测模型在一项大型前瞻性队列研究中的前瞻性验证

JOURNAL OF MEDICAL GENETICS
IF3.7
2022-09-2646
OAAI
Yang, Xin; Eriksson, Mikael; Czene, Kamila; Lee, Andrew; Leslie, Goska; Lush, Michael; Wang, Jean; Dennis, Joe; Dorling, Leila; Carvalho, Sara; Mavaddat, Nasim; Simard, Jacques; Schmidt, Marjanka K.; Easton, Douglas F.; Hall, Per; Antoniou, Antonis C.
Rare germline copy number variants (CNVs) and breast cancer risk

罕见种系拷贝数变异 (CNVs) 与乳腺癌风险

COMMUNICATIONS BIOLOGY
IF5.1
2022-01-1813
OAAI
Dennis, Joe; Tyrer, Jonathan P.; Walker, Logan C.; Michailidou, Kyriaki; Dorling, Leila; Bolla, Manjeet K.; Wang, Qin; Ahearn, Thomas U.; Andrulis, Irene L.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Arndt, Volker; Aronson, Kristan J.; Freeman, Laura E. Beane; Beckmann, Matthias W.; Behrens, Sabine; Benitez, Javier; Bermisheva, Marina; Bogdanova, Natalia, V; Bojesen, Stig E.; Brenner, Hermann; Castelao, Jose E.; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Clarke, Christine L.; Collee, J. Margriet; Couch, Fergus J.; Cox, Angela; Cross, Simon S.; Czene, Kamila; Devilee, Peter; Dork, Thilo; Dossus, Laure; Eliassen, A. Heather; Eriksson, Mikael; Evans, D. Gareth; Fasching, Peter A.; Figueroa, Jonine; Fletcher, Olivia; Flyger, Henrik; Fritschi, Lin; Gabrielson, Marike; Gago-Dominguez, Manuela; Garcia-Closas, Montserrat; Giles, Graham G.; Gonzalez-Neira, Anna; Guenel, Pascal; Hahnen, Eric; Haiman, Christopher A.; Hall, Per; Hollestelle, Antoinette; Hoppe, Reiner; Hopper, John L.; Howell, Anthony; Jager, Agnes; Jakubowska, Anna; John, Esther M.; Johnson, Nichola; Jones, Michael E.; Jung, Audrey; Kaaks, Rudolf; Keeman, Renske; Khusnutdinova, Elza; Kitahara, Cari M.; Ko, Yon-Dschun; Kosma, Veli-Matti; Koutros, Stella; Kraft, Peter; Kristensen, Vessela N.; Kubelka-Sabit, Katerina; Kurian, Allison W.; Lacey, James, V; Lambrechts, Diether; Larson, Nicole L.; Linet, Martha; Ogrodniczak, Alicja; Mannermaa, Arto; Manoukian, Siranoush; Margolin, Sara; Mavroudis, Dimitrios; Milne, Roger L.; Muranen, Taru A.; Murphy, Rachel A.; Nevanlinna, Heli; Olson, Janet E.; Olsson, Hakan; Park-Simon, Tjoung-Won; Perou, Charles M.; Peterlongo, Paolo; Plaseska-Karanfilska, Dijana; Pylkas, Katri; Rennert, Gad; Saloustros, Emmanouil; Sandler, Dale P.; Sawyer, Elinor J.; Schmidt, Marjanka K.; Schmutzler, Rita K.; Shibli, Rana; Smeets, Ann; Soucy, Penny; Southey, Melissa C.; Swerdlow, Anthony J.; Tamimi, Rulla M.; Taylor, Jack A.; Teras, Lauren R.; Terry, Mary Beth; Tomlinson, Ian; Troester, Melissa A.; Truong, Therese; Vachon, Celine M.; Wendt, Camilla; Winqvist, Robert; Wolk, Alicja; Yang, Xiaohong R.; Zheng, Wei; Ziogas, Argyrios; Simard, Jacques; Dunning, Alison M.; Pharoah, Paul D. P.; Easton, Douglas F.
Splicing predictions, minigene analyses, and ACMG-AMP clinical classification of 42 germline PALB2 splice-site variants
JOURNAL OF PATHOLOGY
IF5.2
2021-12-2816
OA
Valenzuela-Palomo, Alberto; Bueno-Martinez, Elena; Sanoguera-Miralles, Lara; Lorca, Victor; Fraile-Bethencourt, Eugenia; Esteban-Sanchez, Ada; Gomez-Barrero, Susana; Carvalho, Sara; Allen, Jamie; Garcia-Alvarez, Alicia; Perez-Segura, Pedro; Dorling, Leila; Easton, Douglas F.; Devilee, Peter; Vreeswijk, Maaike P. G.; de la Hoya, Miguel; Velasco, Eladio A.
Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2019-05-1671
OAAI
Kerns, Sarah L.; Fachal, Laura; Dorling, Leila; Barnett, Gillian C.; Baran, Andrea; Peterson, Derick R.; Hollenberg, Michelle; Hao, Ke; Di Narzo, Antonio; Ahsen, Mehmet Eren; Pandey, Gaurav; Bentzen, Soren M.; Janelsins, Michelle; Elliott, Rebecca M.; Pharoah, Paul D. P.; Burnet, Neil G.; Dearnaley, David P.; Gulliford, Sarah L.; Hall, Emma; Sydes, Matthew R.; Aguado-Barrera, Miguel E.; Gomez-Caamano, Antonio; Carballo, Ana M.; Peleteiro, Paula; Lobato-Busto, Ramon; Stock, Richard; Stone, Nelson N.; Ostrer, Harry; Usmani, Nawaid; Singhal, Sandeep; Tsuji, Hiroshi; Imai, Takashi; Saito, Shiro; Eeles, Rosalind; DeRuyck, Kim; Parliament, Matthew; Dunning, Alison M.; Vega, Ana; Rosenstein, Barry S.; West, Catharine M. L.
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2018-11-0932
OAAI
Li, Jingmei; Wen, Wei Xiong; Eklund, Martin; Kvist, Anders; Eriksson, Mikael; Christensen, Helene Nordahl; Torstensson, Astrid; Bajalica-Lagercrantz, Svetlana; Dunning, Alison M.; Decker, Brennan; Allen, Jamie; Luccarini, Craig; Pooley, Karen; Simard, Jacques; Dorling, Leila; Easton, Douglas F.; Teo, Soo-Hwang; Hall, Per; Borg, Ake; Gronberg, Henrik; Czene, Kamila
Meta-Analysis of Genome-Wide Association Studies (GWAS) of Late Toxicity in 3,874 Men Treated with Radiation for Prostate Cancer
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
IF6.5
2018-11-011
PREAI
Kerns, S. L.; Fachal, L.; Dorling, L.; Barnett, G.; Burnet, N.; Sydes, M.; Dearnaley, D.; Dunning, A.; Pharoah, P.; Parliament, M. B.; Usmani, N. H.; de Ruyck, K.; Ostrer, H.; Rosenstein, B. S.; Gomez CaamaNo, A.; Carballo, A.; Peleteiro Higuero, P. M.; Vega, A.; West, C. M. L.; Hall, E.
Prevalence of PALB2 mutations in an unselected cohort of breast cancer patients and unaffected individuals from Malaysia and Singapore
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Ng, Patsy P.; Wen, Wei Xiong; Wijaya, Eldarina; Allen, Jamie; Lim, Joanna; Lau, Shao Yan; Decker, Brennan; Pooley, Karen; Dorling, Leila; Luccarini, Craig; Baynes, Caroline; Conroy, Don; Harrington, Patricia; Mariapun, Shivaani; Hasan, Siti Norhidayu; Lee, Daphne Shin-Chin; Lee, Sheau Yee; Yoon, Sook Yee; Yip, Cheng Har; Taib, Nur Aishah; Ho, Weang Kee; Hartman, Mikael; Antoniou, Antonis C.; Dunning, Alison M.; Easton, Douglas F.; Teo, Soo Hwang
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
JOURNAL OF MEDICAL GENETICS
IF3.7
2017-10-0935
OAAI
Wen, Wei Xiong; Allen, Jamie; Lai, Kah Nyin; Mariapun, Shivaani; Hasan, Siti Norhidayu; Ng, Pei Sze; Lee, Daphne Shin-Chi; Lee, Sheau Yee; Yoon, Sook-Yee; Lim, Joanna; Lau, Shao Yan; Decker, Brennan; Pooley, Karen; Dorling, Leila; Luccarini, Craig; Baynes, Caroline; Conroy, Don M.; Harrington, Patricia; Simard, Jacques; Yip, Cheng Har; Taib, Nur Aishah Mohd; Ho, Weang Kee; Antoniou, Antonis C.; Dunning, Alison M.; Easton, Douglas F.; Teo, Soo Hwang
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients
RADIOTHERAPY AND ONCOLOGY
IF5.3
2016-12-0195
OAAI
Andreassen, Christian Nicolaj; Rosenstein, Barry S.; Kerns, Sarah L.; Ostrer, Harry; De Ruysscher, Dirk; Cesaretti, Jamie A.; Barnett, Gillian C.; Dunning, Alison M.; Dorling, Leila; West, Catharine M. L.; Burnet, Neil G.; Elliott, Rebecca; Coles, Charlotte; Hall, Emma; Fachal, Laura; Vega, Ana; Gomez-Caamano, Antonio; Talbot, Christopher J.; Symonds, R. Paul; De Ruyck, Kim; Thierens, Hubert; Ost, Piet; Chang-Claude, Jenny; Seibold, Petra; Popanda, Odilia; Overgaard, Marie; Dearnaley, David; Sydes, Matthew R.; Azria, David; Koch, Christine Anne; Parliament, Matthew; Blackshaw, Michael; Sia, Michael; Fuentes-Raspall, Maria J.; Ramon y Cajal, Teresa; Barnadas, Agustin; Vesprini, Danny; Gutierrez-Enriquez, Sara; Molla, Meritxell; Diez, Orland; Yarnold, John R.; Overgaard, Jens; Bentzen, Soren M.; Alsner, Jan
Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

全基因组关联研究的荟萃分析确定前列腺癌放疗后晚期毒性的遗传标记

EBIOMEDICINE
IF10.8
2016-08-0163
OAAI
Kerns, Sarah L.; Dorling, Leila; Fachal, Laura; Bentzen, Soren; Pharoah, Paul D. P.; Barnes, Daniel R.; Gomez-Caamano, Antonio; Carballo, Ana M.; Dearnaley, David P.; Peleteiro, Paula; Gulliford, Sarah L.; Hall, Emma; Michailidou, Kyriaki; Carracedo, Angel; Sia, Michael; Stock, Richard; Stone, Nelson N.; Sydes, Matthew R.; Tyrer, Jonathan P.; Ahmed, Shahana; Parliament, Matthew; Ostrer, Harry; Rosenstein, Barry S.; Vega, Ana; Burnet, Neil G.; Dunning, Alison M.; Barnett, Gillian C.; West, Catharine M. L.

研究方向

暂未获取到该数据
A
Alison M. Dunning
H 指数:114论文数:882被引数:5.4万
C
Catharine West
H 指数:83论文数:701被引数:2.3万
L
Laura Fachal
H 指数:33论文数:126被引数:8,298
A
Ana Vega
H 指数:53论文数:370被引数:1.1万
N
N.G. Burnet
H 指数:56论文数:371被引数:1.2万
P
Paul D.P. Pharoah
H 指数:150论文数:1,771被引数:9.7万
A
Antonio Gómez‐Caamaño
H 指数:26论文数:225被引数:4,010
G
Gillian C. Barnett
H 指数:30论文数:103被引数:4,494
D
David P. Dearnaley
H 指数:99论文数:660被引数:3.8万
S
Sarah L. Kerns
H 指数:36论文数:164被引数:5,271