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ETS1 suppresses hepatic stellate cell activation and liver fibrosis ETS1抑制肝星状细胞活化和肝纤维化 Lee, Wonseok; Liu, Xiao; Rosenthal, Sara Brin; Miciano, Charlene; Sakane, Sadatsugu; Hokutan, Kanani; Dhar, Debanjan; Kim, Hyun Young; Brenner, David A.; Kisseleva, Tatiana 分享 收藏
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Clinical Trial to Assess the Safety and Tolerability of Anti-IL 23 Monoclonal Antibody Guselkumab in Patients With Alcohol-Associated Liver Disease 评估抗IL 23单克隆抗体Guselkumab在酒精相关性肝病患者中的安全性和耐受性的临床试验 Diaz, Luis Antonio; Morris, Sheldon; Dave, Shravan; Kim, Susy M.; Sarik, Wathnita; Richards, Lisa; Madamba, Egbert; Bettencourt, Ricki; Fulinara, Christian; Pham, Thuy; Miller, Grant; Carvalho-Gontijo Weber, Raquel; Momper, Jeremiah D.; He, Feng; Jain, Sonia; Jamieson, Catriona; Kisseleva, Tatiana; Brenner, David; Loomba, Rohit 分享 收藏
Single-Nuclei RNA Sequencing Shows the Engagement of PPAR-Delta Target Genes Primarily in Hepatocytes and Cholangiocytes by the Selective PPAR-Delta Agonist Seladelpar 单核RNA测序显示，选择性PPAR-δ激动剂Seladelpar主要在肝细胞和胆管细胞中激活PPAR-δ靶基因。 Yamazaki, Tomoo; Yang, Yongqiang; Scholer, David; Yukawa-Muto, Yoshimi; Kouno, Tetsuya; Harberts, Aenne; Sakane, Sadatsugu; Freund, Linton; Hsu, Cynthia L.; Whisenant, Thomas C.; Rosenthal, Sara Brin; Kisseleva, Tatiana; Cable, Edward E.; Schnabl, Bernd 分享 收藏
Induction of MASH in three-dimensional bioprinted human liver tissue 在三维生物打印的人体肝组织中对MASH的诱导 Joshi, Vaidehi; Carter, Dwayne; Chen, Alice E.; Murphy, Keith; Higgins, J. William; Gurel, Mediha; Fuentes, Daisy Chilin; Rosenthal, Sara Brin; Fisch, Kathleen M.; Kisseleva, Tatiana 分享 收藏
Serum amyloid P (PTX2) attenuates hepatic fibrosis in mice by inhibiting the activation of fibrocytes and HSCs Cong, Min; Weber, Raquel Carvalho Gontijo; Sakane, Sadatsugu; Zhang, Vivian; Jiang, Chunyan; Taura, Kojiro; Kodama, Yuzo; Deminicis, Samuele; Ganguly, Souradipta; Brafman, David; Chien, Shu; Kramer, Michael; Lupher, Mark; Brenner, David A.; Xu, Jun; Kisseleva, Tatiana 分享 收藏
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis HIF-2α 在非酒精性脂肪性肝炎中驱动肝Kupffer细胞死亡和促炎性募集的巨噬细胞活化 Jeelani, Ishtiaq; Moon, Jae-Su; da Cunha, Flavia Franco; Nasamran, Chanond A.; Jeon, Seokhyun; Zhang, Xinhang; Bandyopadhyay, Gautam K.; Dobaczewska, Katarzyna; Mikulski, Zbigniew; Hosseini, Mojgan; Liu, Xiao; Kisseleva, Tatiana; Brenner, David A.; Singh, Seema; Loomba, Rohit; Kim, Minkyu; Lee, Yun Sok 分享 收藏
Lipid- associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2 脂质相关巨噬细胞在MASH回归期间促进纤维化消退需要TREM2 Ganguly, Souradipta; Rosenthal, Sara Brin; Ishizuka, Kei; Troutman, Ty D.; Rohm, Theresa, V; Khader, Naser; Aleman-Muench, German; Sano, Yasuyo; Archilei, Sebastiano; Soroosh, Pejman; Olefsky, Jerrold M.; Feldstein, Ariel E.; Kisseleva, Tatiana; Loomba, Rohit; Glass, Christopher K.; Brenner, David A.; Dhar, Debanjan 分享 收藏
The Origin and Fate of Liver Myofibroblasts 肝肌成纤维细胞的起源和命运 Kim, Hyun Young; Sakane, Sadatsugu; Eguileor, Alvaro; Weber, Raquel Carvalho Gontijo; Lee, Wonseok; Liu, Xiao; Lam, Kevin; Ishizuka, Kei; Rosenthal, Sara Brin; Diggle, Karin; Brenner, David A.; Kisseleva, Tatiana 分享 收藏
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Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness 果糖-1，6-双磷酸酶是一种非酶安全阀，可减少AKT激活以防止胰岛素高反应性 Gu, Li; Zhu, Yahui; Watari, Kosuke; Lee, Maiya; Liu, Junlai; Perez, Sofia; Thai, Melinda; Mayfield, Joshua E.; Zhang, Bichen; Cunha e Rocha, Karina; Li, Fuming; Kim, Laura C.; Jones, Alexander C.; Wierzbicki, Igor H.; Liu, Xiao; Newton, Alexandra C.; Kisseleva, Tatiana; Lee, Jun Hee; Ying, Wei; Gonzalez, David J.; Saltiel, Alan R.; Simon, M. Celeste; Karin, Michael 分享 收藏
IgY antibodies against cytolysin reduce ethanol-induced liver disease in mice Cabre, Noemi; Hartmann, Phillipp; Llorente, Cristina; Kouno, Tetsuya; Wang, Yanhan; Zeng, Suling; Kim, Hyun Young; Zhang, Xinlian; Kisseleva, Tatiana; Iyer, Subramanian; Kudumala, Sirisha; Schnabl, Bernd 分享 收藏
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis 肝星状细胞中的自分泌信号传导回路是非酒精性脂肪性肝炎晚期纤维化的基础 Wang, Shuang; Li, Kenneth; Pickholz, Eliana; Dobie, Ross; Matchett, Kylie P.; Henderson, Neil C.; Carrico, Chris; Driver, Ian; Jensen, Martin Borch; Chen, Li; Petitjean, Mathieu; Bhattacharya, Dipankar; Fiel, Maria I.; Liu, Xiao; Kisseleva, Tatiana; Alon, Uri; Adler, Miri; Medzhitov, Ruslan; Friedman, Scott L. 分享 收藏
Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis Gao, Hong; Jin, Zhongmou; Bandyopadhyay, Gautam; Wang, Gaowei; Zhang, Dinghong; Rocha, Karina Cunha e; Liu, Xiao; Zhao, Huayi; Kisseleva, Tatiana; Brenner, David A.; Karin, Michael; Ying, Wei 分享 收藏
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