Stanley H. Appel - Publications, H-index & Citations

Stanley H. Appel

houston methodist hospital

101H指数

495论文数

4.3W被引数

收录论文 101

发表时间

Integrated single-cell and spatial transcriptomic profiling in ALS uncovers peripheral-to-central immune infiltration and reprogramming ALS中整合的单细胞和空间转录组分析揭示了外周到中枢的免疫浸润和重编程

Nature Neuroscience

IF20

2026-05-14

OAAI

Ziyang Zhang; Lynn van Olst; Francesco Alessandrini; Matthew Wright; Alex J. Edwards; Jake Boles; Anait Nalbandian; Anne V. Forsyth; Nate Shepard; Thomas Watson; Evan Kaspi; Angeli Mittal; Joshua Kuruvilla; Natalie Piehl; Abhirami Ramakrishnan; Stanley Appel; Evangelos Kiskinis; David Gate

Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease 帕金森病中与炎症和氧化应激相关的周围单核细胞转录特征

Frontiers in Immunology

IF5.9

2025-07-23

OAAI

Aaron D. Thome; Jinghong Wang; Farah Atassi; Jason R. Thonhoff; Alireza Faridar; Weihua Zhao; David R. Beers; Eugene C. Lai; Stanley H. Appel

The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology

NATURE REVIEWS NEUROLOGY

IF33.1

2024-05-20

OAAI

Benatar, Michael; Wuu, Joanne; Huey, Edward D.; Mcmillan, Corey T.; Petersen, Ronald C.; Postuma, Ronald; Mchutchison, Caroline; Dratch, Laynie; Arias, Jalayne J.; Crawley, Anita; Houlden, Henry; McDermott, Michael P.; Cai, Xueya; Thakur, Neil; Boxer, Adam; Rosen, Howard; Boeve, Bradley F.; Dacks, Penny; Cosentino, Stephanie; Abrahams, Sharon; Shneider, Neil; Lingor, Paul; Shefner, Jeremy; Andersen, Peter M.; Al-Chalabi, Ammar; Turner, Martin R.; Allred, Peggy; Appel, Stanley; Benatar, David; Berry, James; Bradbury, Meg; Bruijn, Lucie; Buczyner, Jennifer; Carberry, Nathan; Caress, James; Champney, Thomas; Dave, Kuldip; Fradette, Stephanie; Granit, Volkan; Grignon, Anne-Laure; Gubitz, Amelie; Harms, Matthew; Heiman-Patterson, Terry; Hesterlee, Sharon; Lawrence, Karen; Lewis, Travis; Levy, Oren; Lingor, Paul; Mozaffar, Tahseen; Stanislaw, Christine; Thompson, Alexander; Uspenskay, Olga; Weydt, Patrick; Zinman, Lorne

Primary visual cortex pathology in ALS patients with C9ORF72 expansion

BRAIN PATHOLOGY

IF6.2

2023-11-27

OAAI

Cykowski, Matthew D.; Arumanayagam, Anithachristy S.; Powell, Suzanne Z.; Appel, Stanley H.

A phase 1 open-label pilot study of low-dose interleukine-2 immunotherapy in patients with Alzheimer's disease

TRANSLATIONAL NEURODEGENERATION

IF15.2

2023-11-16

OAAI

Faridar, Alireza; Eid, Abdulmunaim M.; Thome, Aaron D.; Zhao, Weihua; Beers, David R.; Pascual, Maria B.; Nakawah, Mohammad O.; Roman, Gustavo C.; Davis, Charles S.; Grundman, Michael; Masdeu, Joseph C.; Appel, Stanley H.

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION

IF7.5

2022-11-01

OAAI

Thonhoff, Jason R.; Berry, James D.; Macklin, Eric A.; Beers, David R.; Mendoza, Patricia A.; Zhao, Weihua; Thome, Aaron D.; Triolo, Fabio; Moon, James J.; Paganoni, Sabrina; Cudkowicz, Merit; Appel, Stanley H.

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2022-09-30

OAAI

Faridar, Alireza; Vasquez, Matthew; Thome, Aaron D.; Yin, Zheng; Xuan, Hui; Wang, Jing Hong; Wen, Shixiang; Li, Xuping; Thonhoff, Jason R.; Zhao, Weihua; Zhao, Hong; Beers, David R.; Wong, Stephen T. C.; Masdeu, Joseph C.; Appel, Stanley H.

Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-06-22

OAAI

Thome, Aaron D.; Thonhoff, Jason R.; Zhao, Weihua; Faridar, Alireza; Wang, Jinghong; Beers, David R.; Appel, Stanley H.

Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS

ANNALS OF NEUROLOGY

IF7.7

2022-05-07

OAAI

Beers, David R.; Thonhoff, Jason R.; Faridar, Alireza; Thome, Aaron D.; Zhao, Weihua; Wen, Shixiang; Appel, Stanley H.

Amyotrophic lateral sclerosis is a systemic disease: peripheral contributions to inflammation-mediated neurodegeneration 肌萎缩性侧索硬化症是一种全身性疾病: 外周对炎症介导的神经变性的贡献

CURRENT OPINION IN NEUROLOGY

IF4.4

2021-08-16

PREAI

Appel, Stanley H.; Beers, David R.; Zhao, Weihua

Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2021-08-01

OAAI

Cathcart, Sahara J.; Appel, Stanley H.; Peterson, Leif E.; Greene, Ericka P.; Powell, Suzanne Z.; Arumanayagam, Anithachristy S.; Rivera, Andreana L.; Cykowski, Matthew D.

Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS) Protocol and Study Design

NEUROLOGY-CLINICAL PRACTICE

IF3.2

2021-08-01

OAAI

Berry, James; Brooks, Benjamin; Genge, Angela; Heiman-Patterson, Terry; Appel, Stanley; Benatar, Michael; Bowser, Robert; Cudkowicz, Merit; Gooch, Clifton; Shefner, Jeremy; Westra, Jurjen; Agnese, Wendy; Merrill, Charlotte; Nelson, Sally; Apple, Stephen

Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease

NPJ PARKINSONS DISEASE

IF8.2

2021-05-13

OAAI

Thome, Aaron D.; Atassi, Farah; Wang, Jinghong; Faridar, Alireza; Zhao, Weihua; Thonhoff, Jason R.; Beers, David R.; Lai, Eugene C.; Appel, Stanley H.

Detection of endothelial cell-associated human DNA reveals transplanted human bone marrow stem cell engraftment into CNS capillaries of ALS mice

BRAIN RESEARCH BULLETIN

IF3.7

2021-05-01

OAAI

Garbuzova-Davis, Svitlana; Boccio, Kayla J.; Ehrhart, Jared; Sanberg, Paul R.; Appel, Stanley H.; Borlongan, Cesario, V

Neuroinflammation is highest in areas of disease progression in semantic dementia

BRAIN

IF11.7

2021-04-06

OAAI

Pascual, Belen; Funk, Quentin; Zanotti-Fregonara, Paolo; Cykowski, Matthew D.; Veronese, Mattia; Rockers, Elijah; Bradbury, Kathleen; Yu, Meixiang; Nakawah, Mohammad O.; Roman, Gustavo C.; Schulz, Paul E.; Arumanayagam, Anithachristy S.; Beers, David; Faridar, Alireza; Fujita, Masahiro; Appel, Stanley H.; Masdeu, Joseph C.

Serum programmed cell death proteins in amyotrophic lateral sclerosis

brain behavior and immunity

IF0

2021-03-01

OAAI

Beers, David R.; Zhao, Weihua; Thonhoff, Jason R.; Faridar, Alireza; Thome, Aaron D.; Wen, Shixiang; Wang, Jinghong; Appel, Stanley H.

Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis

SCIENTIFIC REPORTS

IF3.9

2020-09-17

OAAI

Beers, David R.; Zhao, Weihua; Neal, Daniel W.; Thonhoff, Jason R.; Thome, Aaron D.; Faridar, Alireza; Wen, Shixiang; Wang, Jinghong; Appel, Stanley H.

Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion

BRAIN COMMUNICATIONS

IF4.5

2020-07-20

OAAI

Faridar, Alireza; Thome, Aaron D.; Zhao, Weihua; Thonhoff, Jason R.; Beers, David R.; Pascual, Belen; Masdeu, Joseph C.; Appel, Stanley H.

Spinal Cord and Motor Neuron TDP-43 Pathology in a Sporadic Inclusion Body Myositis Patient

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2020-07-01

OAAI

Cathcart, Sahara J.; Greene, Ericka P.; Powell, Suzanne Z.; Arumanayagam, Anithachristy S.; Rivera, Andreana L.; Tawil, Rabi; Appel, Stanley H.; Cykowski, Matthew D.

Dipeptide repeat (DPR) pathology in the skeletal muscle of ALS patients with C9ORF72 repeat expansion

ACTA NEUROPATHOLOGICA

IF9.3

2019-08-02

OAAI

Cykowski, Matthew D.; Dickson, Dennis W.; Powell, Suzanne Z.; Arumanayagam, Anithachristy S.; Rivera, Andreana L.; Appel, Stanley H.

研究方向