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收藏分享 收藏 Impact of Single Halogen Atom Substitutions on Antiviral Profile of Inhibitors Targeting SARS-CoV-2 Main Protease
Bulut, Haydar; Higashi-Kuwata, Nobuyo; Ogata-Aoki, Hiromi; Hayashi, Hironori; Takamune, Nobutoki; Kishimoto, Naoki; Das, Debananda; Li, Mi; Wlodawer, Alexander; Misumi, Shogo; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 Targeting envelope lipids with 2,6-di-O-methyl-3-acetyl-β-cyclodextrin impairs infectivity of SARS-CoV-2 and Japanese encephalitis virusKusakari, D.; Kishimoto, N.; Oshiro, K.; Udeda, Y.; Takamune, N.; Motoyama, K.; Misumi, S. 使用2,6-二-O-甲基-3-乙酰基-β-环糊精靶向包膜脂质会损害SARS-CoV-2和日本脑炎病毒的感染性。J. Virol. 2025, 99, e01357-25. [Google Scholar] [CrossRef] [PubMed]Kusakari, Daichi; Kishimoto, Naoki; Oshiro, Kazuyuki; Udeda, Yui; Takamune, Nobutoki; Motoyama, Keiichi; Misumi, Shogo 分享 收藏 分享 收藏 分享 收藏 An orally available P1′-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrierHigashi-Kuwata, Nobuyo; Bulut, Haydar; Hayashi, Hironori; Tsuji, Kohei; Ogata-Aoki, Hiromi; Kiso, Maki; Takamune, Nobutoki; Kishimoto, Naoki; Hattori, Shin-ichiro; Ishii, Takahiro; Kobayakawa, Takuya; Nakano, Kenta; Shimizu, Yukiko; Das, Debananda; Saruwatari, Junji; Hasegawa, Kazuya; Murayama, Kazutaka; Sukenaga, Yoshikazu; Takamatsu, Yuki; Yoshimura, Kazuhisa; Aoki, Manabu; Furusawa, Yuri; Okamura, Tadashi; Yamayoshi, Seiya; Kawaoka, Yoshihiro; Misumi, Shogo; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 Total Syntheses of Phorbol and 11 Tigliane Diterpenoids and Their Evaluation as HIV Latency-Reversing AgentsWatanabe, Ayumu; Nagatomo, Masanori; Hirose, Akira; Hikone, Yuto; Kishimoto, Naoki; Miura, Satoshi; Yasutake, Tae; Abe, Towa; Misumi, Shogo; Inoue, Masayuki 分享 收藏 GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variantsAoki, Manabu; Aoki-Ogata, Hiromi; Bulut, Haydar; Hayashi, Hironori; Takamune, Nobutoki; Kishimoto, Naoki; Tanaka, Hiroki; Higashi-Kuwata, Nobuyo; Hattori, Shin-ichiro; Das, Debananda; Rao, Kalapala Venkateswara; Iwama, Kazuya; Davis, David A.; Hasegawa, Kazuya; Murayama, Kazutaka; Yarchoan, Robert; Ghosh, Arun K.; Pau, Alice K.; Machida, Shinichi; Misumi, Shogo; Mitsuya, Hiroaki 分享 收藏 Synthesis and Biological Evaluation of Simplified Ansellone Analogues with Lipophilic Side Chains as HIV Latency-Reversing AgentsYanagihara, Mizushi; Kishimoto, Naoki; Nakahara, Kanae; Abe, Towa; Miura, Satoshi; Lin, Bangzhong; Fumimoto, Megumi; Haruta, Junichi; Misumi, Shogo; Arisawa, Mitsuhiro; Murai, Kenichi 分享 收藏 Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2Higashi-Kuwata, Nobuyo; Tsuji, Kohei; Hayashi, Hironori; Bulut, Haydar; Kiso, Maki; Imai, Masaki; Ogata-Aoki, Hiromi; Ishii, Takahiro; Kobayakawa, Takuya; Nakano, Kenta; Takamune, Nobutoki; Kishimoto, Naoki; Hattori, Shin-ichiro; Das, Debananda; Uemura, Yukari; Shimizu, Yosuke; Aoki, Manabu; Hasegawa, Kazuya; Suzuki, Satoshi; Nishiyama, Akie; Saruwatari, Junji; Shimizu, Yukiko; Sukenaga, Yoshikazu; Takamatsu, Yuki; Tsuchiya, Kiyoto; Maeda, Kenji; Yoshimura, Kazuhisa; Iida, Shun; Ozono, Seiya; Suzuki, Tadaki; Okamura, Tadashi; Misumi, Shogo; Kawaoka, Yoshihiro; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 分享 收藏 Isolation, Synthesis, and Structure-Activity Relationship Study on Daphnane and Tigliane Diterpenes as HIV Latency-Reversing AgentsEl-Desoky, Ahmed H. H.; Eguchi, Keisuke; Kishimoto, Naoki; Asano, Toshifumi; Kato, Hikaru; Hitora, Yuki; Kotani, Shunsuke; Nakamura, Teruya; Tsuchiya, Soken; Kawahara, Teppei; Watanabe, Masato; Wada, Mikiyo; Nakajima, Makoto; Watanabe, Takashi; Misumi, Shogo; Tsukamoto, Sachiko 分享 收藏 Identification of a novel long-acting 4′-modified nucleoside reverse transcriptase inhibitor against HBVHigashi-Kuwata, Nobuyo; Hayashi, Sanae; Kumamoto, Hiroki; Ogata-Aoki, Hiromi; Das, Debananda; Venzon, David; Hattori, Shin-ichiro; Bulut, Haydar; Hashimoto, Mai; Otagiri, Masaki; Takamune, Nobutoki; Kishimoto, Naoki; Davis, David A.; Misumi, Shogo; Kakuni, Masakazu; Tanaka, Yasuhito; Mitsuya, Hiroaki 分享 收藏 分享 收藏 A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replicationHattori, Shin-ichiro; Higashi-Kuwata, Nobuyo; Hayashi, Hironori; Allu, Srinivasa Rao; Raghavaiah, Jakka; Bulut, Haydar; Das, Debananda; Anson, Brandon J.; Lendy, Emma K.; Takamatsu, Yuki; Takamune, Nobutoki; Kishimoto, Naoki; Murayama, Kazutaka; Hasegawa, Kazuya; Li, Mi; Davis, David A.; Kodama, Eiichi N.; Yarchoan, Robert; Wlodawer, Alexander; Misumi, Shogo; Mesecar, Andrew D.; Ghosh, Arun K.; Mitsuya, Hiroaki 分享 收藏 GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 InfectionGRL-0920，一种吲哚氯吡啶基酯，完全阻断SARS-CoV-2感染Hattori, Shin-ichiro; Higshi-Kuwata, Nobuyo; Raghavaiah, Jakka; Das, Debananda; Bulut, Haydar; Davis, David A.; Takamatsu, Yuki; Matsuda, Kouki; Takamune, Nobutoki; Kishimoto, Naoki; Okamura, Tadashi; Misumi, Shogo; Yarchoan, Robert; Maeda, Kenji; Ghosh, Arun K.; Mitsuya, Hiroaki 分享 收藏 分享 收藏 分享 收藏 Analysis of expressed sequence tags in apomictic guineagrass (Panicum maximum)分析无性基因几内亚草 (Panicum maximum) 中表达的序列标签Yamada-Akiyama, Hitomi; Akiyama, Yukio; Ebina, Masumi; Xu, Qiusheng; Tsuruta, Shin-ichi; Yazaki, Junshi; Kishimoto, Naoki; Kikuchi, Shoshi; Takahara, Manabu; Takamizo, Tadashi; Sugita, Shin-ichi; Nakagawa, Hitoshi 分享 收藏 
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