Richard P. Davis - Publications, H-index & Citations

Richard P. Davis

leiden university medical center

41H指数

214论文数

7.0K被引数

收录论文 55

发表时间

Human iPSC models of myocardial infarction: From injury to repair and therapeutic discovery 人源诱导多能干细胞心肌梗死模型：从损伤到修复及治疗发现

Cell Reports Medicine

IF10.6

2026-09-25

OAAI

Benjamin B. Johnson; Christine L. Mummery; Richard P. Davis

STRAIGHT-IN Dual: a platform for dual single-copy integrations of DNA payloads and gene circuits into human induced pluripotent stem cells STRAIGHT-IN Dual：一种将DNA有效载荷和基因回路进行双单拷贝整合到人诱导多能干细胞中的平台

Nature Biomedical Engineering

IF26.6

2026-04-30

OAAI

Albert Blanch-Asensio; Deon S. Ploessl; Benjamin B. Johnson; Sara Cascione; Myrthe R. M. Berndsen; Nathan B. Wang; Valeria V. Orlova; Anna Alemany; Christine L. Mummery; Kate E. Galloway; Richard P. Davis

Gene syntax defines supercoiling-mediated transcriptional feedback 基因语法定义超螺旋介导的转录反馈

Science

IF45.8

2026-04-30

PREAI

Christopher P. Johnstone; Kasey S. Love; Sneha R. Kabaria; Ross D. Jones; Albert Blanch-Asensio; Deon S. Ploessl; Emma L. Peterman; Rachel Lee; Jiyoung Yun; Conrad G. Oakes; Christine L. Mummery; Richard P. Davis; Brandon J. DeKosky; Peter W. Zandstra; Kate E. Galloway

A simplified co-culture reveals altered cardiotoxic responses to doxorubicin in hPSC-derived cardiomyocytes in the presence of endothelial cells 简化共培养体系揭示了在存在内皮细胞的情况下，人源多能干细胞来源的心肌细胞对多柔比星的心脏毒性反应发生改变。

Stem Cell Reports

IF5.1

2026-02-12

OAAI

Marcella Brescia; James Gallant; Andrea Chatrian; Paul Keselman; Elsa Sörman Paulsson; Mervyn P.H. Mol; Rickard Sjögren; Karine Raymond; Valeria Orlova; Kalpana Barnes; Richard Wales; Jonas Austerjost; Michael W. Olszowy; Christine L. Mummery; Berend J. van Meer; Richard P. Davis

Industrialization of 3D hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening 3D hiPSC心脏微组织的工业化生产用于高通量心脏安全性和药物发现筛选

Trends in Biotechnology

IF14.9

2025-12-18

OAAI

Tessa de Korte; Benjamin B. Johnson; Georgios Kosmidis; Benoit Samson-Couterie; Mervyn P.H. Mol; Ruben W.J. van Helden; Ehsan Razaghi; Louise François; Viviana Meraviglia; Loukia Yiangou; Tom Kuipers; Hailiang Mei; Milena Bellin; Stefan R. Braam; Shushant Jain; Christine L. Mummery; Richard P. Davis

Tapered Pillar Design for High-Precision Force Readout in Miniaturized Engineered Heart Tissues From Human Pluripotent Stem Cells 从人胚胎干细胞中构建的微型化工程心脏组织中，用于高精度力读出的锥形支柱设计

Advanced Healthcare Materials

IF9.6

2025-08-30

OAAI

Milica Dostanić; Maury Wiendels; Laura M. Windt; Mervyn P.H. Mol; Francijna E. van den Hil; Richard P. Davis; Valeria Orlova; Berend J. van Meer; Massimo Mastrangeli; Christine L. Mummery

Validating human induced pluripotent stem cell-specific fi c quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system

CYTOTHERAPY

IF3.2

2024-09-01

OAAI

Novoa, Juan; Westra, Inge; Steeneveld, Esther; Neves, Natascha Fonseca; Daleman, Lizanne; Asensio, Albert Blanch; Davis, Richard P.; Carlotti, Francoise; Freund, Christian; Rabelink, Ton; Meij, Pauline; Wieles, Brigitte

STRAIGHT-IN: a platform for rapidly generating panels of genetically modified human pluripotent stem cell lines 直入: 快速生成转基因人类多能干细胞系面板的平台

NATURE PROTOCOLS

IF16

2024-08-23

PREAI

Blanch-Asensio, Albert; Grandela, Catarina; Mummery, Christine L.; Davis, Richard P.

Chronic Mexiletine Administration Increases Sodium Current in Non-Diseased Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

BIOMEDICINES

IF3.9

2024-05-29

OAAI

Nasilli, Giovanna; Verkerk, Arie O.; O'Reilly, Molly; Yiangou, Loukia; Davis, Richard P.; Casini, Simona; Remme, Carol Ann

Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs

NATURE BIOMEDICAL ENGINEERING

IF26.6

2024-05-22

OAAI

Li, Yufeng; Tan, Minkang; Akkari-Henic, Almira; Zhang, Limin; Kip, Maarten; Sun, Shengnan; Sepers, Jorian J.; Xu, Ningning; Ariyurek, Yavuz; Kloet, Susan L.; Davis, Richard P.; Mikkers, Harald; Gruber, Joshua J.; Snyder, Michael P.; Li, Xiao; Pang, Baoxu

Global Meta-Analysis of Organoid and Organ-on-Chip Research 类器官和器官芯片研究的全球荟萃分析

ADVANCED HEALTHCARE MATERIALS

IF9.6

2023-08-07

OAAI

Shoji, Jun-ya; Davis, Richard P.; Mummery, Christine L.; Krauss, Stefan

Beneficial effects of chronic mexiletine treatment in a human model of SCN5A overlap syndrome

EUROPACE

IF7.4

2023-06-27

OAAI

Nasilli, Giovanna; Yiangou, Loukia; Palandri, Chiara; Cerbai, Elisabetta; Davis, Richard P.; Verkerk, Arie O.; Casini, Simona; Remme, Carol Ann

STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells 直入式能够高通量靶向人类多能干细胞中的大DNA有效载荷

CELL REPORTS METHODS

IF4.5

2022-10-01

OAAI

Blanch-Asensio, Albert; Grandela, Catarina; Brandao, Karina O.; de Korte, Tessa; Mei, Hailiang; Ariyurek, Yavuz; Yiangou, Loukia; Mol, Mervyn P. H.; van Meer, Berend J.; Kloet, Susan L.; Mummery, Christine L.; Davis, Richard P.

Optogenetic Reporters Delivered as mRNA Facilitate Repeatable Action Potential and Calcium Handling Assessment in Human iPSC-Derived Cardiomyocytes 作为mRNA传递的光遗传学报道分子可促进人类iPSC衍生的心肌细胞中可重复的动作电位和钙处理评估

Stem Cells

IF3.6

2022-04-16

OAAI

Yiangou, Loukia; Blanch-Asensio, Albert; de Korte, Tessa; Miller, Duncan C.; van Meer, Berend J.; Mol, Mervyn P. H.; van den Brink, Lettine; Brandao, Karina O.; Mummery, Christine L.; Davis, Richard P.

Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia

CARDIOVASCULAR RESEARCH

IF13.3

2022-04-08

OAAI

Campostrini, Giulia; Kosmidis, Georgios; Ward-van Oostwaard, Dorien; Davis, Richard P.; Yiangou, Loukia; Ottaviani, Daniele; Veerman, Christiaan C.; Mei, Hailiang; Orlova, Valeria V.; Wilde, Arthur A. M.; Bezzina, Connie R.; Verkerk, Arie O.; Mummery, Christine L.; Bellin, Milena

The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2

FRONTIERS IN PHYSIOLOGY

IF3.4

2021-12-16

OAAI

van den Brink, Lettine; Brandao, Karina O.; Yiangou, Loukia; Blanch-Asensio, Albert; Mol, Mervyn P. H.; Mummery, Christine L.; Verkerk, Arie O.; Davis, Richard P.

Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells 人多能干细胞来源的等基因三维自聚集心脏微组织的生成、功能分析及应用

NATURE PROTOCOLS

IF16

2021-03-26

OAAI

Campostrini, Giulia; Meraviglia, Viviana; Giacomelli, Elisa; van Helden, Ruben W. J.; Yiangou, Loukia; Davis, Richard P.; Bellin, Milena; Orlova, Valeria V.; Mummery, Christine L.

Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

CLINICAL EPIGENETICS

IF4.4

2021-03-23

OAAI

Pei, J.; Schuldt, M.; Nagyova, E.; Gu, Z.; el Bouhaddani, S.; Yiangou, L.; Jansen, M.; Calis, J. J. A.; Dorsch, L. M.; Blok, C. Snijders; van den Dungen, N. A. M.; Lansu, N.; Boukens, B. J.; Efimov, I. R.; Michels, M.; Verhaar, M. C.; de Weger, R.; Vink, A.; van Steenbeek, F. G.; Baas, A. F.; Davis, R. P.; Uh, H. W.; Kuster, D. W. D.; Cheng, C.; Mokry, M.; van der Velden, J.; Asselbergs, F. W.; Harakalova, M.

Using Cardiovascular Cells from Human Pluripotent Stem Cells for COVID-19 Research: the Heart Fails

STEM CELL REPORTS

IF5.1

2021-03-01

OAAI

Yiangou, Loukia; Davis, Richard P.; Mummery, Christine L.

Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias

STEM CELL REPORTS

IF5.1

2020-11-01

OAAI

Brandao, Karina O.; van den Brink, Lettine; Miller, Duncan C.; Grandela, Catarina; van Meer, Berend J.; Mol, Mervyn P. H.; de Korte, Tessa; Tertoolen, Leon G. J.; Mummery, Christine L.; Sala, Luca; Verkerk, Arie O.; Davis, Richard P.

研究方向