Pascal Loyer - Publications, H-index & Citations

Pascal Loyer

inrae

38H指数

136论文数

4.7K被引数

收录论文 53

发表时间

Lentiviral-mediated expression of cytochrome P450 2D6 in HepaRG cells: new means for in vitro xenobiotic biotransformation and cellular response to chimeric viral mRNA 慢病毒介导的细胞色素P450 2D6在HepaRG细胞中的表达：体外外源物生物转化和细胞对嵌合病毒mRNA反应的新方法

Archives of Toxicology

IF6.9

2026-05-21

PREAI

Hugo Coppens-Exandier; Franz Mackanga; Thomas Darde; Corentin Bonhomme; Gaëlle Angenard; Patricia Leroyer; Catherine Ribault; Thomas Gicquel; Romain Pelletier; Flyuza Roshchina; Estelle Schaefer; Christophe Chesné; Agnès Jamin; Anne Corlu; Pascal Loyer

Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation 上皮转录因子GRHL2的去抑制促进了直接的肝细胞到胆管细胞的转分化

PLOS BIOLOGY

IF7.2

2025-12-12

PREAI

Vasseur, Ludivine; Gheeraert, Celine; Dubois-Chevalier, Julie; Very, Ninon; Guille, Loic; Bou Saleh, Mohamed; Boulet, Clemence; Sobolewski, Cyril; Loyer, Pascal; Berthier, Alexandre; Legrand, Noemie; Corlu, Anne; Gnemmi, Viviane; Lasailly, Guillaume; Leteurtre, Emmanuelle; Galinousky, Dmitry; Bongiovanni, Antonino; Taront, Solenne; Toft, Nicolaj I.; Grontved, Lars; Tulasne, David; Furlan, Alessandro; Ntandja-Wandji, Line Carolle; Staels, Bart; Lefebvre, Philippe; Dubuquoy, Laurent; Eeckhoute, Jerome

The dithiocarbamate pesticides maneb and mancozeb disturb the metabolism of lipids and xenobiotics in an in vitro model of metabolic dysfunction-associated steatotic liver disease 二硫代氨基甲酸酯类农药代森锰和代森锰锌扰乱代谢功能障碍相关脂肪性肝病体外模型的脂质和 xenobiotics 代谢

Environmental Toxicology and Pharmacology

IF4.2

2025-07-22

OAAI

Kilian Petitjean; Giovanna Dicara; Sébastien Bristeau; Hugo Coppens-Exandier; Laurence Amalric; Nicole Baran; Camille C. Savary; Anne Corlu; Pascal Loyer; Bernard Fromenty

Interactions between PEI and biological polyanions and the ability of glycosaminoglycans in destabilizing PEI/peGFP-C3 polyplexes for genetic material release 聚乙烯亚胺（PEI）与生物多聚阴离子之间的相互作用以及糖胺聚糖（glycosaminoglycans）破坏PEI/peGFP-C3聚复体以释放遗传物质的能力

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2025-04-01

PREAI

Montano-Gonzalez, Paulina; Bravo-Lozano, Lizeth Montserrat; Chevance, Soizic; Dole, Francois; Rosselgong, Julien; Loyer, Pascal; Tranchimand, Sylvain; Chapel, Jean-Paul; Gauffre, Fabienne; Schatz, Christophe; Bravo-Anaya, Lourdes Monica

Internalization and mechanisms of toxicity of lipid nanocapsules in HepG2 and HepaRG hepatoma cells upon acute and chronic exposures

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2024-12-01

OAAI

Delaporte, Flavien; Roger, Emilie; Bejaud, Jerome; Loyer, Pascal; Lagarce, Frederic; Savary, Camille C.

Synthesis, characterization and stability of crosslinked chitosan-maltodextrin pH-sensitive nanogels

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2024-08-01

PREAI

Gricelda Fernandez-Solis, Karla; Dominguez-Fonseca, Estefania; Gonzalez Martinez, Brianda Maria; Gutierrez Becerra, Alberto; Figueroa Ochoa, Edgar; Mendizabal, Eduardo; Toriz, Guillermo; Loyer, Pascal; Rosselgong, Julien; Monica Bravo-Anaya, Lourdes

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Trembley, JH; Tatsumi, S; Sakashita, E; Loyer, P; Slaughter, CA; Suzuki, H; Endo, H; Kidd, VJ; Mayeda, A

Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression

CELLS

IF5.2

2022-12-02

OAAI

Vlach, Manuel; Coppens-Exandier, Hugo; Jamin, Agnes; Berchel, Mathieu; Scaviner, Julien; Chesne, Christophe; Montier, Tristan; Jaffres, Paul-Alain; Corlu, Anne; Loyer, Pascal

Circumsporozoite Protein of Plasmodium berghei- and George Baker Virus A-Derived Peptides Trigger Efficient Cell Internalization of Bioconjugates and Functionalized Poly(ethylene glycol)-b-poly(benzyl malate)-Based Nanoparticles in Human Hepatoma Cells

PHARMACEUTICS

IF5.5

2022-04-06

OAAI

Vene, Elise; Jarnouen, Kathleen; Ribault, Catherine; Vlach, Manuel; Verres, Yann; Bourgeois, Mickael; Lepareur, Nicolas; Cammas-Marion, Sandrine; Loyer, Pascal

Synthesis of Poly(Malic Acid) Derivatives End-Functionalized with Peptides and Preparation of Biocompatible Nanoparticles to Target Hepatoma Cells

NANOMATERIALS

IF4.3

2021-04-09

OAAI

Brossard, Clarisse; Vlach, Manuel; Vene, Elise; Ribault, Catherine; Dorcet, Vincent; Noiret, Nicolas; Loyer, Pascal; Lepareur, Nicolas; Cammas-Marion, Sandrine

Roles of CDK/Cyclin complexes in transcription and pre-mRNA splicing: Cyclins L and CDK11 at the cross-roads of cell cycle and regulation of gene expression

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2020-11-01

OAAI

Loyer, Pascal; Trembley, Janeen H.

Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy

MOLECULES

IF4.6

2020-09-02

OAAI

Eychenne, Romain; Bouvry, Christelle; Bourgeois, Mickael; Loyer, Pascal; Benoist, Eric; Lepareur, Nicolas

Alteration of immunophenotype of human macrophages and monocytes after exposure to cigarette smoke

SCIENTIFIC REPORTS

IF3.9

2020-07-30

OAAI

da Silva, Camila Oliveira; Gicquel, Thomas; Daniel, Yoann; Bartholo, Thiago; Vene, Elise; Loyer, Pascal; Porto, Luis Cristovao; Lagente, Vincent; Victoni, Tatiana

Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity

SENSORS

IF3.5

2019-05-15

OAAI

Vlach, Manuel; Quesnot, Nicolas; Dubois-Pot-Schneider, Helene; Ribault, Catherine; Verres, Yann; Petitjean, Kilian; Rauch, Claudine; Morel, Fabrice; Robin, Marie-Anne; Corlu, Anne; Loyer, Pascal

Bulk Organocatalytic Synthetic Access to Statistical Copolyesters from L-Lactide and ε-Caprolactone Using Benzoic Acid

BIOMACROMOLECULES

IF5.4

2019-04-09

OAAI

Mezzasalma, Leila; Harrisson, Simon; Saba, Saad; Loyer, Pascal; Coulembier, Olivier; Taton, Daniel

Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes

ARCHIVES OF TOXICOLOGY

IF6.9

2018-08-27

OAAI

Quesnot, Nicolas; Bucher, Simon; Gade, Christina; Vlach, Manuel; Vene, Elise; Valenca, Samuel; Gicquel, Thomas; Holst, Helle; Robin, Marie-Anne; Loyer, Pascal

Dosimetric parameters predicting contralateral liver hypertrophy after unilobar radioembolization of hepatocellular carcinoma

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2017-11-25

OAAI

Palard, Xavier; Edeline, Julien; Rolland, Yan; Le Sourd, Samuel; Pracht, Marc; Laffont, Sophie; Lenoir, Laurence; Boudjema, Karim; Ugen, Thomas; Brun, Vanessa; Mesbah, Habiba; Haumont, Laure-Anne; Loyer, Pascal; Garin, Etienne

Efficient transfection of Xenobiotic Responsive Element-biosensor plasmid using diether lipid and phosphatidylcholine liposomes in differentiated HepaRG cells

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2017-05-01

OAAI

Demazeau, Maxime; Quesnot, Nicolas; Ripoche, Nicolas; Rauch, Claudine; Jeftic, Jelena; Morel, Fabrice; Gauffre, Fabienne; Benvegnu, Thierry; Loyer, Pascal

Poly(malic acid) bearing Doxorubicin and N-Acetyl Galactosamine as a site-specific prodrug for targeting hepatocellular carcinoma

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

IF3.6

2017-04-07

OAAI

Venkatraj, Nivishna; Nanjan, M. J.; Loyer, Pascal; Chandrasekar, M. J. N.; Marion, Sandrine Cammas

Opsonisation of nanoparticles prepared from poly(β-hydroxybutyrate) and poly(trimethylene carbonate)-b-poly(malic acid) amphiphilic diblock copolymers: Impact on the in vitro cell uptake by primary human macrophages and HepaRG hepatoma cells

INTERNATIONAL JOURNAL OF PHARMACEUTICS

IF5.2

2016-11-01

OAAI

Vene, Elise; Barouti, Ghislaine; Jarnouen, Kathleen; Gicquel, Thomas; Rauch, Claudine; Ribault, Catherine; Guillaume, Sophie M.; Cammas-Marion, Sandrine; Loyer, Pascal

研究方向