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R

Roland Kappler

lmu munich

36H指数
198论文数
5.4K被引数
收录论文 50
发表时间
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Preclinical Drug-Response Profiling Identifies BMI1 Inhibition as a Therapeutic Option for Hepatoblastoma临床前药物反应分析确定BMI1抑制可作为肝母细胞瘤的治疗方案
errInternational Journal of Molecular Sciences
IF4.9
err2026-06-10
err0
errOAAI
errSalih Demir; Marie Friederike Bentrop; Alina Hotes; Tanja Schmid; Emilie Indersie; Sophie Branchereau; Christian Vokuhl; Beate Häberle; Irene Schmid; Stefano Cairo; Roland Kappler
err分享
err收藏
Proteasome Targeting with Carfilzomib Induces Reactive Oxygen Species-Mediated Apoptosis in Hepatoblastoma卡非佐米靶向蛋白酶体诱导肝母细胞瘤中活性氧介导的凋亡
errCells
IF5.2
err2026-05-09
err0
errOAAI
errElena Johanna Weigl; Salih Demir; Alina Hotes; Emilie Indersie; Sophie Branchereau; Stefano Cairo; Roland Kappler
err分享
err收藏
Mechanistic models position ceritinib as a nuclear integrity disrupting therapy in pediatric liver tumors机制模型将ceritinib定位为一种破坏儿科肝肿瘤细胞核完整性的疗法
errJournal of Experimental & Clinical Cancer Research
IF12.8
err2025-10-03
err0
errOAAI
errSalih Demir; Thomas Kessler; Alina Hotes; Beate Häberle; Eiso Hiyama; Tomoro Hishiki; Emilie Indersie; Sophie Branchereau; Christian Vokuhl; Mathurin Dorel; Hans Lehrach; Bodo Lange; Stefano Cairo; Roland Kappler
err分享
err收藏
Mimicking cancer therapy in an agent-based model: The case of hepatoblastoma基于代理模型模拟癌症疗法：以肝母细胞瘤为例
errComputer Methods and Programs in Biomedicine
IF4.8
err2025-06-25
err0
errOAAI
errAlessandro Ravoni; Enrico Mastrostefano; Roland Kappler; Carolina Armengol; Filippo Castiglione; Christine Nardini
err分享
err收藏
Identification of a Growth-Promoting Gene Cluster in the Region 2q24 as a Driver of Tumorigenesis in Childhood Hepatoblastoma在2q24区域鉴定出一个促生长基因簇，作为儿童肝母细胞瘤发生发展的驱动因素。
erramerican journal of pathology
IF0
err2025-04-30
err0
PREAI
errMartin M. Rodemann; Verena Dreschmann; Evelyn Dörner; Anette Sommer; Joern Kraetzschmar; Ludger Klein-Hitpass; Genta Nagae; Eiso Hiyama; Dietrich von Schweinitz; Roland Kappler; Christian Vokuhl; Torsten Pietsch
err分享
err收藏
Targeting HSP90 with Ganetespib to Induce CDK1 Degradation and Promote Cell Death in Hepatoblastoma靶向HSP90以诱导CDK1降解并促进肝母细胞瘤细胞死亡
errCANCERS
IF4.4
err2025-04-16
err0
errOAAI
errJung, Lea Amelie; Demir, Salih; Hotes, Alina; Hiyama, Eiso; Hishiki, Tomoro; Indersie, Emilie; Branchereau, Sophie; Cairo, Stefano; Kappler, Roland
err分享
err收藏
Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma
errJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
err2024-11-12
err0
errOAAI
errDemir, Salih; Hotes, Alina; Schmid, Tanja; Cairo, Stefano; Indersie, Emilie; Pisano, Claudio; Hiyama, Eiso; Hishiki, Tomoro; Vokuhl, Christian; Branchereau, Sophie; Brock, Penelope; Schmid, Irene; Zsiros, Jozsef; Kappler, Roland
err分享
err收藏
A patient-derived xenograft in vitro platform identifies panobinostat as the most efficient drug to treat high-risk hepatoblastoma patients
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errDemir, Salih; Indersie, Emilie; Branchereau, Sophie; Hiyama, Eiso; Cairo, Stefano; Kappler, Roland
err分享
err收藏
Targeting G9a/DNMT1 methyltransferase activity impedes IGF2-mediated survival in hepatoblastoma
errHEPATOLOGY COMMUNICATIONS
IF4.6
err2024-02-01
err8
errOAAI
errDemir, Salih; Razizadeh, Negin; Indersie, Emilie; Branchereau, Sophie; Cairo, Stefano; Kappler, Roland
err分享
err收藏
Computational drug prediction in hepatoblastoma by integrating pan-cancer transcriptomics with pharmacological response
errHEPATOLOGY
IF15.8
err2023-09-20
err4
errOAAI
errFailli, Mario; Demir, Salih; Del Rio-Alvarez, Alvaro; Carrillo-Reixach, Juan; Royo, Laura; Domingo-Sabat, Montserrat; Childs, Margaret; Maibach, Rudolf; Alaggio, Rita; Czauderna, Piotr; Morland, Bruce; Branchereau, Sophie; Cairo, Stefano; Kappler, Roland; Armengol, Carolina; di Bernardo, Diego
err分享
err收藏
A combined clinical and biological risk classification improves prediction of outcome in hepatoblastoma patients
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2020-12-01
err14
errOAAI
errCairo, Stefano; Armengol, Carolina; Maibach, Rudolf; Haeberle, Beate; Becker, Kristina; Carrillo-Reixach, Juan; Guettier, Catherine; Vokuhl, Christian; Schmid, Irene; Buendia, Marie-Annick; Branchereau, Sophie; von Schweinitz, Dietrich; Kappler, Roland
err分享
err收藏
Multiomics approach identifies the SP8-FGF8 axis as an important promoter of metastatic features in hepatoblastoma
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errWagner, Alexandra; Haeberle, Beate; Schmid, Irene; Vokuhl, Christian; von Schweinitz, Dietrich; Kappler, Roland
err分享
err收藏
Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications
errJOURNAL OF HEPATOLOGY
IF33
err2020-08-01
err83
errOAAI
errCarrillo-Reixach, Juan; Torrens, Laura; Simon-Coma, Marina; Royo, Laura; Domingo-Sabat, Montserrat; Abril-Fornaguera, Jordi; Akers, Nicholas; Sala, Margarita; Ragull, Sonia; Arnal, Magdalena; Villalmanzo, Nuria; Cairo, Stefano; Villanueva, Alberto; Kappler, Roland; Garrido, Marta; Guerra, Laura; Sabado, Constantino; Guillen, Gabriela; Mallo, Mar; Pineyro, David; Vazquez-Vitali, Maria; Kuchuk, Olga; Elena Mateos, Maria; Ramirez, Gema; Lopez Santamaria, Manuel; Mozo, Yasmina; Soriano, Aroa; Grotzer, Michael; Branchereau, Sophie; Garcia de Andoin, Nagore; Lopez-Ibor, Blanca; Lopez-Almaraz, Ricardo; Antonio Salinas, Jose; Torres, Barbara; Hernandez, Francisco; Javier Uriz, Jose; Fabre, Monique; Blanco, Julia; Paris, Claudia; Bajciova, Viera; Laureys, Genevieve; Masnou, Helena; Clos, Ariadna; Belendez, Cristina; Guettier, Catherine; Sumoy, Lauro; Planas, Ramon; Jorda, Mireia; Nonell, Lara; Czauderna, Piotr; Morland, Bruce; Sia, Daniela; Losic, Bojan; Buendia, Marie Annick; Rosa Sarrias, Maria; Llovet, Josep M.; Armengol, Carolina
err分享
err收藏
A scientific task force to generate proof-of-concept data packages for clinical trials in pediatric cancers: The hepatoblastoma example
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errArmengol, Carolina; Kappler, Roland; Zhu, Liqin; Timchenko, Nikolai; Kats, Dina; Keller, Charles; Howard, Lisa; Grosset, Christophe; Nicolle, Delphine; Deas, Olivier; Pigazzi, Martina; Brugieres, Laurence; Mussini, Charlotte; Galmiche-Rolland, Louise; Chardot, Christophe; Brancereau, Sophie; Judde, Jean-Gabriel; Cairo, Stefano
err分享
err收藏
Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma
errCLINICAL EPIGENETICS
IF4.4
err2018-03-02
err42
errOAAI
errBeck, Alexander; Trippel, Franziska; Wagner, Alexandra; Joppien, Saskia; Felle, Max; Vokuhl, Christian; Schwarzmayr, Thomas; Strom, Tim M.; von Schweinitz, Dietrich; Laengst, Gernot; Kappler, Roland
err分享
err收藏
MiR-492 regulates metastatic properties of hepatoblastoma via CD44
errLIVER INTERNATIONAL
IF5.2
err2018-01-25
err30
errOAAI
errvon Frowein, Julia; Hauck, Stefanie M.; Kappler, Roland; Pagel, Philipp; Fleischmann, Katrin K.; Magg, Thomas; Cairo, Stefano; Roscher, Adelbert; von Schweinitz, Dietrich; Schmid, Irene
err分享
err收藏
Transcriptional activation of Hedgehog pathway components in aggressive haemangioma
errEXPERIMENTAL DERMATOLOGY
IF3.1
err2017-08-15
err3
PREAI
errWendling-Keim, Danielle S.; Wanie, Lynn; von Schweinitz, Dietrich; Grantzow, Rainer; Kappler, Roland
err分享
err收藏
Combined clinical and biological risk stratification in pediatric hepatoblastoma
errCANCER RESEARCH
IF16.6
err2017-07-01
err0
PREAI
errCairo, Stefano; Armengol, Carolina; Haberle, Beate; Simon-Coma, Marina; Guettier, Catherine; Leuschner, Ivo; Buendia, Marie-Annick; von Schweinitz, Dietrich; Kappler, Roland
err分享
err收藏
Connectivity map identifies HDAC inhibition as a treatment option of high-risk hepatoblastoma
errCANCER BIOLOGY & THERAPY
IF4.6
err2016-09-16
err21
errOAAI
errBeck, Alexander; Eberherr, Corinna; Hagemann, Michaela; Cairo, Stefano; Haeberle, Beate; Vokuhl, Christian; von Schweinitz, Dietrich; Kappler, Roland
err分享
err收藏
Patient- Derived Mouse Xenografts From Pediatric Liver Cancer Predict Tumor Recurrence and Advise Clinical Management
errHEPATOLOGY
IF15.8
err2016-06-16
err54
errOAAI
errNicolle, Delphine; Fabre, Monique; Simon-Coma, Marina; Gorse, Aurore; Kappler, Roland; Nonell, Lara; Mallo, Mar; Haidar, Hazar; Deas, Olivier; Mussini, Charlotte; Guettier, Catherine; Redon, Marie-Jose; Brugieres, Laurence; Ghigna, Maria Rosa; Fadel, Elie; Galmiche-Rolland, Louise; Chardot, Christophe; Judde, Jean-Gabriel; Armengol, Carolina; Branchereau, Sophie; Cairo, Stefano
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
J
Josep M. Llovet
H 指数: 151 · 论文数: 794
T
Tim M. Strom
H 指数: 109 · 论文数: 714
E
Elisabeth Kremmer
H 指数: 109 · 论文数: 508
F
Felix Beuschlein
H 指数: 105 · 论文数: 1.0K
K
Klaus‐Michael Debatin
H 指数: 99 · 论文数: 1.4K
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