Jan B. Parys - Publications, H-index & Citations

Jan B. Parys

KU Leuven

75H指数

332论文数

3.2W被引数

收录论文 139

发表时间

The IP3 receptor-KRAP complex at the desmosomes: A new player in the apoptotic process

CELL CALCIUM

IF4

2024-12-01

PREAI

Parys, Jan B.

The interplay between associated proteins, redox state and Ca2+in the intraluminal ER compartment regulates the IP3 receptor 管腔内ER隔室中相关蛋白，氧化还原状态和Ca2之间的相互作用调节IP3受体

CELL CALCIUM

IF4

2024-01-01

OAAI

Parys, Jan B.; Lemos, Fernanda O.

Modalities of cell death, survival and adaptation: The role of the Ca2+-signaling toolkit 细胞死亡，生存和适应的方式: Ca2信号工具包的作用

CELL CALCIUM

IF4

2023-11-01

OAAI

Parys, Jan B.; Bultynck, Geert

The Complex Effects of PKM2 and PKM2:IP3R Disruption on Intracellular Ca2+ Handling and Cellular Functions PKM2和PKM2:IP3R破坏对细胞内Ca2处理和细胞功能的复杂影响

CELLS

IF5.2

2023-10-26

OAAI

Lemos, Fernanda O.; de Ridder, Ian; Bootman, Martin D.; Bultynck, Geert; Parys, Jan B.

LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner LRRK2磷酸化状态和激酶活性以Rab8a/Rab10-dependent方式调节 (宏) 自噬

CELL DEATH & DISEASE

IF9.6

2023-07-15

OAAI

Kania, Elzbieta; Long, Jaclyn S.; McEwan, David G.; Welkenhuyzen, Kirsten; La Rovere, Rita; Luyten, Tomas; Halpin, John; Lobbestael, Evy; Baekelandt, Veerle; Bultynck, Geert; Ryan, Kevin M.; Parys, Jan B.

The ER-mitochondria interface, where Ca2+and cell death meet

CELL CALCIUM

IF4

2023-06-01

OAAI

de Ridder, Ian; Kerkhofs, Martijn; Lemos, Fernanda O.; Loncke, Jens; Bultynck, Geert; Parys, Jan B.

Modulation of Ca2+signaling by antiapoptotic Bcl-2 versus Bcl-xL: From molecular mechanisms to relevance for cancer cell survival 抗凋亡Bcl-2与bcl-xl对Ca2信号的调节: 从分子机制到癌细胞存活的相关性

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

IF8.3

2022-11-01

OAAI

Rosa, Nicolas; Speelman-Rooms, Femke; Parys, Jan B.; Bultynck, Geert

Sec61 complex/translocon: The role of an atypical ER Ca2+-leak channel in health and disease

FRONTIERS IN PHYSIOLOGY

IF3.4

2022-10-06

OAAI

Parys, Jan B.; Van Coppenolle, Fabien

TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy

LIFE SCIENCE ALLIANCE

IF2.9

2022-06-17

OAAI

Zhang, Li; Dietsche, Felicia; Seitaj, Bruno; Rojas-Charry, Liliana; Latchman, Nadina; Tomar, Dhanendra; Wust, Rob C., I; Nickel, Alexander; Frauenknecht, Katrin B. M.; Schoser, Benedikt; Schumann, Sven; Schmeisser, Michael J.; vom Berg, Johannes; Buch, Thorsten; Finger, Stefanie; Wenzel, Philip; Maack, Christoph; Elrod, John W.; Parys, Jan B.; Bultynck, Geert; Methner, Axel

Rhomboid pseudoproteases: An Achilles heel's for BCL-2/IP3R-dependent resistance to ER stress-induced cell death

CELL CALCIUM

IF4

2022-06-01

PREAI

Lemos, Fernanda O.; de Ridder, Ian; Bultynck, Geert; Parys, Jan B.

TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence TRPC3塑造ER-线粒体Ca2转移，表征肿瘤促进衰老

NATURE COMMUNICATIONS

IF15.7

2022-02-17

OAAI

Farfariello, Valerio; Gordienko, Dmitri, V; Mesilmany, Lina; Touil, Yasmine; Germain, Emmanuelle; Fliniaux, Ingrid; Desruelles, Emilie; Gkika, Dimitra; Roudbaraki, Morad; Shapovalov, George; Noyer, Lucile; Lebas, Mathilde; Allart, Laurent; Zienthal-Gelus, Nathalie; Iamshanova, Oksana; Bonardi, Franck; Figeac, Martin; Laine, William; Kluza, Jerome; Marchetti, Philippe; Quesnel, Bruno; Metzger, Daniel; Bernard, David; Parys, Jan B.; Lemonnier, Loic; Prevarskaya, Natalia

Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis

CELL DEATH AND DIFFERENTIATION

IF15.4

2021-11-08

OAAI

Rosa, Nicolas; Ivanova, Hristina; Wagner, Larry E.; Kale, Justin; La Rovere, Rita; Welkenhuyzen, Kirsten; Louros, Nikolaos; Karamanou, Spyridoula; Shabardina, Victoria; Lemmens, Irma; Vandermarliere, Elien; Hamada, Kozo; Ando, Hideaki; Rousseau, Frederic; Schymkowitz, Joost; Tavernier, Jan; Mikoshiba, Katsuhiko; Economou, Anastassios; Andrews, David W.; Parys, Jan B.; Yule, David, I; Bultynck, Geert

Uniting the divergent Wolfram syndrome-linked proteins WFS1 and CISD2 as modulators of Ca2+ signaling

SCIENCE SIGNALING

IF6.6

2021-09-28

OAAI

Loncke, Jens; Vervliet, Tim; Parys, Jan B.; Kaasik, Allen; Bultynck, Geert

Balancing ER-Mitochondrial Ca2+Fluxes in Health and Disease

TRENDS IN CELL BIOLOGY

IF18.1

2021-07-01

OAAI

Loncke, Jens; Kaasik, Allen; Bezprozvanny, Ilya; Parys, Jan B.; Kerkhofs, Martijn; Bultynck, Geert

BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening

CELL CALCIUM

IF4

2021-03-01

OAAI

Kerkhofs, Martijn; La Rovere, Rita; Welkenhuysen, Kirsten; Janssens, Ann; Vandenberghe, Peter; Madesh, Muniswamy; Parys, Jan B.; Bultynck, Geert

EPIC3, a novel Ca2+ indicator located at the cell cortex and in microridges, detects high Ca2+ subdomains during Ca2+ influx and phagocytosis

CELL CALCIUM

IF4

2020-12-01

OAAI

Roberts, Rhiannon E.; Vervliet, Tim; Bultynck, Geert; Parys, Jan B.; Hallett, Maurice B.

Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery

CELLS

IF5.2

2020-09-23

OAAI

Seitaj, Bruno; Maull, Felicia; Zhang, Li; Wuellner, Verena; Wolf, Christina; Schippers, Philipp; La Rovere, Rita; Distler, Ute; Tenzer, Stefan; Parys, Jan B.; Bultynck, Geert; Methner, Axel

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

CELLS

IF5.2

2020-08-01

128

OAAI

Sprooten, Jenny; De Wijngaert, Pieter; Vanmeerbeek, Isaure; Martin, Shaun; Vangheluwe, Peter; Schlenner, Susan; Krysko, Dmitri, V; Parys, Jan B.; Bultynck, Geert; Vandenabeele, Peter; Garg, Abhishek D.

L-asparaginase-induced apoptosis in ALL cells involves IP3 receptor signaling

CELL CALCIUM

IF4

2019-11-01

PREAI

Vervliet, Tim; Parys, Jan B.

Full focus on calcium

SCIENCE SIGNALING

IF6.6

2019-09-17

PREAI

Parys, Jan B.; Guse, Andreas H.

研究方向