Young‐Jun Park - Publications, H-index & Citations

Young‐Jun Park

University of Washington

56H指数

233论文数

2.6W被引数

收录论文 69

发表时间

TMPRSS2-mediated coronavirus spike activation and inhibition TMPRSS2介导的冠状病毒刺突蛋白激活与抑制

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-04-28

OAAI

Matthew McCallum; James Brett Case; Jack T. Brown; Young-Jun Park; Jimin Lee; Emmajay Sutherland; Anupriya Aggarwal; Cecily Gibson; Florian A. Lempp; Cameron Stewart; M. Alejandra Tortorici; Shilpa Sanapala; Jun Siong Low; Daniel Asarnow; Dana Bohan; Exequiel Dellota; Benjamin Merz; Bhavna Chawla; Swagata Kar; Antonio Lanzavecchia; Federica Sallusto; Nicholas M. Riley; Stuart Turville; Lisa Purcell; Michael S. Diamond; David Veesler

Eradication of Aspiculuris tetraptera in various immunodeficient mouse models using ivermectin: a case report

Laboratory Animal Research

IF2.9

2026-01-23

OAAI

Ji-Hun Lee; Eun-Seon Yoo; Na-Won Kim; Han-Bi Jeong; Ah-Reum Kang; Sun-Min Seo; Young-Jun Park; Byeong-Cheol Kang; Yang-Kyu Choi

The computationally designed TRI2-2 miniprotein inhibitor protects against multiple SARS-CoV-2 Omicron variants 计算设计的TRI2-2微型蛋白抑制剂可保护免受多种SARS-CoV-2奥密克戎变体侵害

Communications Biology

IF5.1

2026-01-10

OAAI

Jimin Lee; James Brett Case; Young-Jun Park; Rashmi Ravichandran; Daniel Asarnow; M. Alejandra Tortorici; Jack T. Brown; Shilpa Sanapala; Lauren Carter; David Baker; Michael S. Diamond; David Veesler

The unique architecture of umbrella toxins permits a two-tiered molecular bet-hedging strategy for interbacterial antagonism 伞形毒素的独特结构使其能够实现一种分级的分子对冲策略，用于细菌间的拮抗作用。

Cell

IF42.5

2025-12-02

OAAI

Qinqin Zhao; Jiri Vlach; Young-Jun Park; Yongjun Tan; Savannah K. Bertolli; Pooja Srinivas; Pinyu Liao; Connor R. Fitzpatrick; Jeffery L. Dangl; Parastoo Azadi; Frank DiMaio; S. Brook Peterson; Dapeng Zhang; David Veesler; Joseph D. Mougous

Potent neutralization of Marburg virus by a vaccine-elicited antibody 疫苗诱导的抗体对马尔堡病毒的中和作用强效

Nature

IF48.5

2025-11-12

OAAI

Amin Addetia; Lisa Perruzza; Kaitlin Sprouse; Young-Jun Park; Matthew McCallum; Cameron Stewart; Bianca Partini; Jack T. Brown; Alessia Donati; Katja Culap; Alessio Balmelli; Bhavna Chawla; Swagata Kar; Michal Gazi; Kendra Alfson; Yenny Goez-Gazi; Ricardo Carrion; Davide Corti; Fabio Benigni; David Veesler

HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor HKU25分支的MERS相关冠状病毒使用ACE2作为功能受体。

Nature Microbiology

IF19.4

2025-10-30

OAAI

Chen Liu; Young-Jun Park; Cheng-Bao Ma; Risako Gen; Cameron Stewart; Yu-Cheng Sun; Xiao Yang; Mei-Yi Lin; Qing Xiong; Jun-Yu Si; Peng Liu; David Veesler; Huan Yan

Report SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals 报告SARS-CoV-2 nsp1在哺乳动物中介导广泛的翻译抑制

CELL REPORTS

IF6.9

2025-05-01

OAAI

Gen, Risako; Addetia, Amin; Asarnow, Daniel; Park, Young-Jun; Quispe, Joel; Chan, Matthew C.; Brown, Jack T.; Lee, Jimin; Campbell, Melody G.; Lapointe, Christopher P.; Veesler, David

Chaperone-mediated autophagy modulates Snail protein stability: implications for breast cancer metastasis 伴侣介导的自噬调节Snail蛋白的稳定性: 对乳腺癌转移的影响

MOLECULAR CANCER

IF33.9

2024-10-11

OAAI

Ryu, Ki-Jun; Lee, Ki Won; Park, Seung-Ho; Kim, Taeyoung; Hong, Keun-Seok; Kim, Hyemin; Kim, Minju; Ok, Dong Woo; Kwon, Gu Neut Bom; Park, Young-Jun; Kwon, Hyuk-Kwon; Hwangbo, Cheol; Kim, Kwang Dong; Lee, J. Eugene; Yoo, Jiyun

A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines

NATURE COMMUNICATIONS

IF15.7

2024-06-28

OAAI

Lee, Jimin; Stewart, Cameron; Schaefer, Alexandra; Leaf, Elizabeth M.; Park, Young-Jun; Asarnow, Daniel; Powers, John M.; Treichel, Catherine; Sprouse, Kaitlin R.; Corti, Davide; Baric, Ralph; King, Neil P.; Veesler, David

Structure and design of Langya virus glycoprotein antigens 琅琊病毒糖蛋白抗原的结构与设计

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-09

OAAI

Wang, Zhaoqian; Mccallum, Matthew; Yan, Lianying; Gibson, Cecily A.; Sharkey, William; Park, Young - Jun; V. Dang, Ha; Amaya, Moushimi; Person, Ashley; Broder, Christopher C.; Veeslera, David

IL-27-induced PD-L1highSca-1+ innate lymphoid cells suppress contact hypersensitivity in an IL-10-dependent manner

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2024-03-01

OAAI

Min, Keun Young; Kim, Do-Kyun; Jo, Min Geun; Choi, min Yeong; Lee, Dajeong; Park, Jeong Won; Park, Young-Jun; Chung, Yeonseok; Kim, Young Mi; Park, Yeong-Min; Kim, Hyuk Soon; Choi, Wahn Soo

Antigen spacing on protein nanoparticles influences antibody responses to vaccination

CELL REPORTS

IF6.9

2023-12-01

OAAI

Ellis, Daniel; Dosey, Annie; Boyoglu-Barnum, Seyhan; Park, Young -Jun; Gillespie, Rebecca; Syeda, Hubza; Hutchinson, Geoffrey B.; Tsybovsky, Yaroslav; Murphy, Michael; Pettie, Deleah; Matheson, Nick; Chan, Sidney; Ueda, George; Fallas, Jorge A.; Carter, Lauren; Graham, Barney S.; Veesler, David; Kanekiyo, Masaru; King, Neil P.

Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail

CELL REPORTS

IF6.9

2023-06-01

OAAI

Addetia, Amin; Park, Young -Jun; Starr, Tyler; Greaney, Allison J.; Sprouse, Kaitlin R.; Bowen, John E.; Tiles, Sasha W.; Voorhis, Wesley C. Van; Bloom, Jesse D.; Corti, Davide; Walls, Alexandra C.; Veesler, David

SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines

SCIENCE IMMUNOLOGY

IF16.3

2022-12-16

OAAI

Bowen, John E.; Park, Young-Jun; Stewart, Cameron; Brown, Jack T.; Sharkey, William K.; Walls, Alexandra C.; Joshi, Anshu; Sprouse, Kaitlin R.; McCallum, Matthew; Tortorici, M. Alejandra; Franko, Nicholas M.; Logue, Jennifer K.; Mazzitelli, Ignacio G.; Nguyen, Annalee W.; Silva, Rui P.; Huang, Yimin; Low, Jun Siong; Jerak, Josipa; Tiles, Sasha W.; Ahmed, Kumail; Shariq, Asefa; Dan, Jennifer M.; Zhang, Zeli; Weiskopf, Daniela; Sette, Alessandro; Snell, Gyorgy; Posavad, Christine M.; Iqbal, Najeeha Talat; Geffner, Jorge; Bandera, Alessandra; Gori, Andrea; Sallusto, Federica; Maynard, Jennifer A.; Crotty, Shane; Van Voorhis, Wesley C.; Simmerling, Carlos; Grifantini, Renata; Chu, Helen Y.; Corti, Davide; Veesler, David

Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-05-25

OAAI

Hunt, Andrew C.; Case, James Brett; Park, Young-Jun; Cao, Longxing; Wu, Kejia; Walls, Alexandra C.; Liu, Zhuoming; Bowen, John E.; Yeh, Hsien-Wei; Saini, Shally; Helms, Louisa; Zhao, Yan Ting; Hsiang, Tien-Ying; Starr, Tyler N.; Goreshnik, Inna; Kozodoy, Lisa; Carter, Lauren; Ravichandran, Rashmi; Green, Lydia B.; Matochko, Wadim L.; Thomson, Christy A.; Vogeli, Bastian; Kruger, Antje; VanBlargan, Laura A.; Chen, Rita E.; Ying, Baoling; Bailey, Adam L.; Kafai, Natasha M.; Boyken, Scott E.; Ljubetic, Ajasja; Edman, Natasha; Ueda, George; Chow, Cameron M.; Johnson, Max; Addetia, Amin; Navarro, Mary-Jane; Panpradist, Nuttada; Gale, Michael, Jr.; Freedman, Benjamin S.; Bloom, Jesse D.; Ruohola-Baker, Hannele; Whelan, Sean P. J.; Stewart, Lance; Diamond, Michael S.; Veesler, David; Jewett, Michael C.; Baker, David

Structure-based design of stabilized recombinant influenza neuraminidase tetramers

NATURE COMMUNICATIONS

IF15.7

2022-04-05

OAAI

Ellis, Daniel; Lederhofer, Julia; Acton, Oliver J.; Tsybovsky, Yaroslav; Kephart, Sally; Yap, Christina; Gillespie, Rebecca A.; Creanga, Adrian; Olshefsky, Audrey; Stephens, Tyler; Pettie, Deleah; Murphy, Michael; Sydeman, Claire; Ahlrichs, Maggie; Chan, Sidney; Borst, Andrew J.; Park, Young-Jun; Lee, Kelly K.; Graham, Barney S.; Veesler, David; King, Neil P.; Kanekiyo, Masaru

Generation of ordered protein assemblies using rigid three-body fusion 使用刚性三体融合生成有序蛋白质组装体

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-05-31

OAAI

Vulovic, Ivan; Yao, Qing; Park, Young-Jun; Courbet, Alexis; Norris, Andrew; Busch, Florian; Sahasrabuddhe, Aniruddha; Merten, Hannes; Sahtoe, Danny D.; Ueda, George; Fallas, Jorge A.; Weaver, Sara J.; Hsia, Yang; Langan, Robert A.; Plueckthun, Andreas; Wysocki, Vicki H.; Veesler, David; Jensen, Grant J.; Baker, David

Structural basis for broad coronavirus neutralization 广泛的冠状病毒中和的结构基础

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-05-12

146

OAAI

Sauer, Maximilian M.; Tortorici, M. Alejandra; Park, Young-Jun; Walls, Alexandra C.; Homad, Leah; Acton, Oliver J.; Bowen, John E.; Wang, Chunyan; Xiong, Xiaoli; de van der Schueren, Willem; Quispe, Joel; Hoffstrom, Benjamin G.; Bosch, Berend-Jan; McGuire, Andrew T.; Veesler, David

Design of multi-scale protein complexes by hierarchical building block fusion

NATURE COMMUNICATIONS

IF15.7

2021-04-16

OAAI

Hsia, Yang; Mout, Rubul; Sheffler, William; Edman, Natasha, I; Vulovic, Ivan; Park, Young-Jun; Redler, Rachel L.; Bick, Matthew J.; Bera, Asim K.; Courbet, Alexis; Kang, Alex; Brunette, T. J.; Nattermann, Una; Tsai, Evelyn; Saleem, Ayesha; Chow, Cameron M.; Ekiert, Damian; Bhabha, Gira; Veesler, David; Baker, David

Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease

MSPHERE

IF3.1

2020-12-23

OAAI

Rule, Chelsea S.; Park, Young-Jun; Delarosa, Jaclyn R.; Turley, Stewart; Hol, Wim G. J.; McColm, Sarah; Gura, Colby; DiMaio, Frank; Korotkov, Konstantin V.; Sandkvist, Maria

研究方向