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FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation Inhibitors FUT8 是前列腺肿瘤生长的关键驱动因子，并且可以通过岩藻糖基化抑制剂进行靶向治疗。 Bastian, Kayla; Orozco-Moreno, Margarita; Thomas, Huw; Hodgson, Kirsty; Visser, Eline A.; Rossing, Emiel; Pijnenborg, Johan F. A.; Eerden, Nienke; Wilson, Laura; Saravannan, Hasvini; Hanley, Oliver; Grimsley, Grace; Frame, Fiona; Peng, Ziqian; Knight, Bridget; Mccullagh, Paul; Mcgrath, John; Crundwell, Malcolm; Harries, Lorna; Maitland, Norman J.; Heer, Rakesh; Wang, Ning; Goddard-Borger, Ethan D.; Guerrero, Ramon Hurtado; Boltje, Thomas J.; Drake, Richard R.; Scott, Emma; Elliott, David J.; Munkley, Jennifer 分享 收藏
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ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer Garnham, Rebecca; Geh, Daniel; Nelson, Ryan; Ramon-Gil, Erik; Wilson, Laura; Schmidt, Edward N.; Walker, Laura; Adamson, Beth; Buskin, Adriana; Hepburn, Anastasia C.; Hodgson, Kirsty; Kendall, Hannah; Frame, Fiona M.; Maitland, Norman; Coffey, Kelly; Strand, Douglas W.; Robson, Craig N.; Elliott, David J.; Heer, Rakesh; Macauley, Matthew; Munkley, Jennifer; Gaughan, Luke; Leslie, Jack; Scott, Emma 分享 收藏
ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression Scott, Emma; Goode, Emily Archer; Garnham, Rebecca; Hodgson, Kirsty; Orozco-Moreno, Margarita; Turner, Helen; Livermore, Karen; Nangkana, Kyla Putri; Frame, Fiona M.; Bermudez, Abel; Marques, Fernando Jose Garcia; McClurg, Urszula L.; Wilson, Laura; Thomas, Huw; Buskin, Adriana; Hepburn, Anastasia; Duxfield, Adam; Bastian, Kayla; Pye, Hayley; Arredondo, Hector M.; Hysenaj, Gerald; Heavey, Susan; Stopka-Farooqui, Urszula; Haider, Aiman; Freeman, Alex; Singh, Saurabh; Johnston, Edward W.; Punwani, Shonit; Knight, Bridget; McCullagh, Paul; McGrath, John; Crundwell, Malcolm; Harries, Lorna; Heer, Rakesh; Maitland, Norman J.; Whitaker, Hayley; Pitteri, Sharon; Troyer, Dean A.; Wang, Ning; Elliott, David J.; Drake, Richard R.; Munkley, Jennifer 分享 收藏
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth Scott, Emma; Hodgson, Kirsty; Calle, Beatriz; Turner, Helen; Cheung, Kathleen; Bermudez, Abel; Marques, Fernando Jose Garcia; Pye, Hayley; Yo, Edward Christopher; Islam, Khirul; Oo, Htoo Zarni; McClurg, Urszula L.; Wilson, Laura; Thomas, Huw; Frame, Fiona M.; Orozco-Moreno, Margarita; Bastian, Kayla; Arredondo, Hector M.; Roustan, Chloe; Gray, Melissa Anne; Kelly, Lois; Tolson, Aaron; Mellor, Ellie; Hysenaj, Gerald; Goode, Emily Archer; Garnham, Rebecca; Duxfield, Adam; Heavey, Susan; Stopka-Farooqui, Urszula; Haider, Aiman; Freeman, Alex; Singh, Saurabh; Johnston, Edward W.; Punwani, Shonit; Knight, Bridget; McCullagh, Paul; McGrath, John; Crundwell, Malcolm; Harries, Lorna; Bogdan, Denisa; Westaby, Daniel; Fowler, Gemma; Flohr, Penny; Yuan, Wei; Sharp, Adam; de Bono, Johann; Maitland, Norman J.; Wisnovsky, Simon; Bertozzi, Carolyn R.; Heer, Rakesh; Guerrero, Ramon Hurtado; Daugaard, Mads; Leivo, Janne; Whitaker, Hayley; Pitteri, Sharon; Wang, Ning; Elliott, David J.; Schumann, Benjamin; Munkley, Jennifer 分享 收藏
The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates Buhigas, Claudia; Warren, Anne Y.; Leung, Wing-Kit; Whitaker, Hayley C.; Luxton, Hayley J.; Hawkins, Steve; Kay, Jonathan; Butler, Adam; Xu, Yaobo; Woodcock, Dan J.; Merson, Sue; Frame, Fiona M.; Sahli, Atef; Abascal, Federico; Martincorena, Inigo; Bova, G. Steven; Foster, Christopher S.; Campbell, Peter; Maitland, Norman J.; Neal, David E.; Massie, Charlie E.; Lynch, Andy G.; Eeles, Rosalind A.; Cooper, Colin S.; Wedge, David C.; Brewer, Daniel S. 分享 收藏
Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer Ibrahim, Ali I. M.; Batlle, Elisabet; Sneha, Smarakan; Jimenez, Rafael; Pequerul, Raquel; Pares, Xavier; Rungeler, Till; Jha, Vibhu; Tuccinardi, Tiziano; Sadiq, Maria; Frame, Fiona; Maitland, Norman J.; Farres, Jaume; Pors, Klaus 分享 收藏
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STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population Canesin, Giacomo; Maggio, Valentina; Palominos, Macarena; Stiehm, Anna; Contreras, Hector R.; Castellon, Enrique A.; Morote, Juan; Paciucci, Rosanna; Maitland, Norman J.; Bjartell, Anders; Hellsten, Rebecka 分享 收藏
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The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy Seed, Robert I.; Taurozzi, Alberto J.; Wilcock, Daniel J.; Nappo, Giovanna; Erb, Holger H. H.; Read, Martin L.; Gurney, Mark; Archer, Leanne K.; Ito, Saburo; Rumsby, Martin G.; Petrie, John L.; Clayton, Aled; Maitland, Norman J.; Collins, Anne T. 分享 收藏
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Synthesis and biologic evaluation of diethylbenzaldehyde analogues to probe functional activity of aldehyde dehydrogenase activity in cancer Ibrahim, Ali; Sadiq, Maria; Presa, Daniela; Ntafoulis, Ioannis; Alkawi, Ahmad; Frame, Fiona; Maitland, Norman J.; Cournia, Zoe; Loadman, Paul M.; Moreb, Jan; Pors, Klaus 分享 收藏
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