Angela M. Lam

Center for Macau Studies and Department of Communication

28H指数

95论文数

3.5K被引数

收录论文 33

发表时间

Resilient outcomes in people with a history of mental disorder during the COVID-19 pandemic: an international 2-years longitudinal prospective study 具有精神障碍史者在COVID-19疫情期间的韧性结局：一项国际性2年纵向前瞻性研究

Social Psychiatry and Psychiatric Epidemiology

IF3.5

2025-06-23

PREAI

I. Pinucci; F. Tedeschi; R. Serra; M. Patanè; C. Acartürk; D. Andriani; R. A. Bryant; S. Burchert; G. Caggiu; D. Campos; C. Conflitti; C. Davisse-Paturet; M. Felez-Nobrega; D. Fuhr; B. J. Hall; J. M. Haro; A. C. Huizink; C. Knaevelsrud; G. Kurt; A. Lam; I. Leijen; R. Mediavilla; M. Melchior; E. Mittendorfer-Rutz; N. Morina; M. Monzio Compagnoni; P. Nicaise; C. Palantza; C. Panter-Brick; D. Papola; S. Quero; C. Rodriguez Prada; S. Seedat; H. Setyowibowo; P. Smith; J. van der Waerden; H. Walter; A. Witteveen; M. Pasquini; M. Sijbrandij; C. Barbui; L. Tarsitani

Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2′,1′:2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-11-08

PREAI

Gotchev, Dimitar; Chen, Shuai; Dugan, Benjamin; Dorsey, Bruce D.; Wang, Xu; Sheraz, Muhammad; Kowalski, Rose; Liu, Fei; Tang, Sunny; Chiu, Tim; Harasym, Troy; Graves, Ingrid E.; Thi, Emily P.; Mason, Jeremy D.; Overholt, Nathan; Dugyala, Ravi; Lam, Angela M.; Cole, Andrew G.; Sofia, Michael J.

Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA Therapeutic 用小干扰RNA治疗剂Imdusiran控制乙型肝炎病毒

ACS INFECTIOUS DISEASES

IF3.8

2024-09-22

PREAI

Thi, Emily P.; Ye, Xin; Snead, Nicholas M.; Lee, Amy C. H.; Steuer, Holly M. Micolochick; Ardzinski, Andrzej; Graves, Ingrid E.; Espiritu, Christine; Cuconati, Andrea; Abbott, Cory; Jarosz, Agnes; Teng, Xiaowei; Paratala, Bhavna; McClintock, Kevin; Harasym, Troy; Rijnbrand, Rene; Lam, Angela M.; Sofia, Michael J.

Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-09-03

PREAI

Mesaros, Eugen F.; Cole, Andrew G.; Kultgen, Steven G.; Mani, Nagraj; Fan, Kristi Yi; Dugan, Benjamin J.; Ardzinski, Andrzej; Stever, Kim; Steuer, Holly M. Micolochick; Graves, Ingrid; Tang, Sunny; Harasym, Troy O.; Lam, Angela M.; Thi, Emily P.; Dorsey, Bruce D.; Sofia, Michael J.

Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2 发现对SARS-CoV-2具有抗病毒活性的C-连接核苷类似物

ACS INFECTIOUS DISEASES

IF3.8

2024-04-23

PREAI

Mesaros, Eugen F.; Dugan, Benjamin J.; Gao, Min; Sheraz, Muhammad; McGovern-Gooch, Kayleigh; Xu, Fran; Fan, Kristi Yi; Nguyen, Duyan; Kultgen, Steven G.; Lindstrom, Aaron; Stever, Kim; Tercero, Breanna; Binder, Randall J.; Liu, Fei; Micolochick Steuer, Holly M.; Mani, Nagraj; Harasym, Troy O.; Thi, Emily P.; Cuconati, Andrea; Dorsey, Bruce D.; Cole, Andrew G.; Lam, Angela M.; Sofia, Michael J.

Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161

VIRUSES-BASEL

IF3.5

2024-02-21

OAAI

Lam, Angela M.; Dugyala, Ravi R.; Sheraz, Muhammed; Liu, Fei; Thi, Emily P.; Graves, Ingrid E.; Cuconati, Andrea; Steuer, Holly Micolochick; Ardzinski, Andrzej; Overholt, Nathan; Mason, Jeremy D.; Gotchev, Dimitar; Cole, Andrew G.; Harasym, Troy O.; Sofia, Michael J.

Pregenomic RNA Launch Hepatitis B Virus Replication System Facilitates the Mechanistic Study of Antiviral Agents and Drug-Resistant Variants on Covalently Closed Circular DNA Synthesis

JOURNAL OF VIROLOGY

IF3.8

2022-12-21

OAAI

Zhao, Qiong; Chang, Jinhong; Rijnbrand, Rene; Lam, Angela M.; Sofia, Michael J.; Cuconati, Andrea; Guo, Ju-Tao

415 Virtual Reality Simulator use in Orthopaedic Training: What do the Trainees Think?

BRITISH JOURNAL OF SURGERY

IF8.7

2022-08-19

PREAI

Hunt, Laurence; Lubwama, Baker; Al-Uzri, Muntadhir; Lam, Angela; Kang, Niel

Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA

JOURNAL OF VIROLOGY

IF3.8

2021-08-25

OAAI

Liu, Fei; Lee, Amy C. H.; Guo, Fang; Kondratowicz, Andrew S.; Steuer, Holly M. Micolochick; Miller, Angela; Bailey, Lauren D.; Wang, Xiaohe; Chen, Shuai; Kultgen, Steven G.; Cuconati, Andrea; Cole, Andrew G.; Gotchev, Dimitar; Dorsey, Bruce D.; Rijnbrand, Rene; Lam, Angela M.; Sofia, Michael J.; Gao, Min

P450s under Restriction (PURE) Screen Using HepaRG and Primary Human Hepatocytes for Discovery of Novel HBV Antivirals

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2020-02-26

OAAI

Hartman, George D.; Kuduk, Scott D.; Espiritu, Christine; Lam, Angela M.

Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection

JOURNAL OF HEPATOLOGY

IF33

2019-12-01

OAAI

Faure-Dupuy, Suzanne; Delphin, Marion; Aillot, Ludovic; Dimier, Laura; Lebosse, Fanny; Fresquet, Judith; Parent, Romain; Matter, Matthias Sebastian; Rivoire, Michel; Bendriss-Vermare, Nathalie; Salvetti, Anna; Heide, Danijela; Flores, Lalo; Klumpp, Klaus; Lam, Angela; Zoulim, Fabien; Heikenwaelder, Mathias; Durantel, David; Lucifora, Julie

Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2019-01-01

OAAI

Lam, Angela M.; Espiritu, Christine; Vogel, Robert; Ren, Suping; Lau, Vincent; Kelly, Mollie; Kuduk, Scott D.; Hartman, George D.; Flores, Osvaldo A.; Klumpp, Klaus

Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection NVR 3-778，单独和联合聚乙二醇化干扰素，与恩替卡韦在具有人源化肝脏和HBV感染的uPA/SCID小鼠中的功效

GASTROENTEROLOGY

IF25.1

2018-02-01

PREAI

Klumpp, Klaus; Shimada, Takashi; Allweiss, Lena; Volz, Tassilo; Luetgehetmann, Marc; Hartman, George; Flores, Osvaldo A.; Lam, Angela M.; Dandri, Maura

Hepatitis B Virus Capsid Assembly Modulators, but Not Nucleoside Analogs, Inhibit the Production of Extracellular Pregenomic RNA and Spliced RNA Variants

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-08-01

OAAI

Lam, Angela M.; Ren, Suping; Espiritu, Christine; Kelly, Mollie; Lau, Vincent; Zheng, Lingjie; Hartman, George D.; Flores, Osvaldo A.; Klumpp, Klaus

No changes in the coding sequence for HBV core protein after 6 weeks of treatment of HBV infected humanized mice with NVR 3-778

JOURNAL OF HEPATOLOGY

IF33

2017-01-01

PREAI

Lam, A. M.; Shimada, T.; Dandri, M.; Flores, L.; Klumpp, K.

High-resolution crystal structure of a hepatitis B virus replication inhibitor bound to the viral core protein 与病毒核心蛋白结合的乙型肝炎病毒复制抑制剂的高分辨率晶体结构

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-11-23

155

OAAI

Klumpp, Klaus; Lam, Angela M.; Lukacs, Christine; Vogel, Robert; Ren, Suping; Espiritu, Christine; Baydo, Ruth; Atkins, Kateri; Abendroth, Jan; Liao, Guochun; Efimov, Andrey; Hartman, George; Flores, Osvaldo A.

EFFECT OF THE COMBINATION OF THE HBV CORE INHIBITOR NVR 3-778 WITH NUCLEOSIDE ANALOGS OR OTHER HBV CORE INHIBITORS ON THE INHIBITION OF HBVDNA REPLICATION IN HepG2.2.15 CELLS

JOURNAL OF HEPATOLOGY

IF33

2015-04-01

PREAI

Lam, A.; Espiritu, C.; Flores, O.; Hartman, G.; Klumpp, K.

Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2014-11-01

OAAI

Lam, Angela M.; Edwards, Thomas E.; Mosley, Ralph T.; Murakami, Eisuke; Bansal, Shalini; Lugo, Christopher; Bao, Haiying; Otto, Michael J.; Sofia, Michael J.; Furman, Phillip A.

Discovery of a Novel Class of Potent HCV NS4B Inhibitors: SAR Studies on Piperazinone Derivatives

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-01-29

PREAI

Kakarla, Ramesh; Liu, Jian; Naduthambi, Devan; Chang, Wonsuk; Mosley, Ralph T.; Bao, Donghui; Steuer, Holly-M. Micolochick; Keilman, Meg; Bansal, Shalini; Lam, Angela M.; Seibel, William; Neilson, Sandra; Furman, Phillip A.; Sofia, Michael J.

Use of 2′-Spirocyclic Ethers in HCV Nucleoside Design

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-10-18

PREAI

Du, Jinfa; Chun, Byoung-Kwon; Mosley, Ralph T.; Bansal, Shalini; Bao, Haiying; Espiritu, Christine; Lam, Angela M.; Murakami, Eisuke; Niu, Congrong; Steuer, Holly M. Micolochick; Furman, Phillip A.; Sofia, Michael J.

研究方向