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Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer 定义支持胰腺癌KRAS-和ERK依赖性生长的MYC调控转录组与激酶组 Hibshman, Priya S.; Stalnecker, Clint A.; Klomp, Jeffrey A.; Drizyte-Miller, Kristina; Klomp, Jennifer E.; Edwards, A. Cole; Pita, Lily M.; Hodge, Richard G.; Diehl, J. Nathaniel; Mouery, Ryan D.; Mouery, Brandon L.; Snare, Kayla R.; Waters, Andrew M.; Peng, Sen; Barker, Natalie K.; Pierobon, Mariaelena; Rashid, Naim U.; Tran, Nhan L.; Herring, Laura A.; Graves, Lee M.; Petricoin, Emanuel F.; Bryant, Kirsten L.; Cox, Adrienne D.; Der, Channing J. 分享 收藏
T-type calcium channels regulate medulloblastoma and can be targeted for therapy T型钙通道调节髓母细胞瘤，可作为靶向治疗 Dube, Collin J.; Lai, Michelle; Zhang, Ying; Saha, Shekhar; Yener, Ulas; Hanif, Farina; Hudson, Kadie; Gibert Jr, Myron K.; Marcinkiewicz, Pawel; Sun, Yunan; Vegiraju, Tanvika; Xu, Esther; Sorot, Aditya; Gallagher, Rosa I.; Wulfkuhle, Julia D.; Vernon, Ashley; Dell'Olio, Lily; Anbu, Rajitha; Mulcahy, Elizabeth; Kefas, Benjamin; Guessous, Fadila; Petricoin, Emanuel F.; Abounader, Roger 分享 收藏
Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment 发育状态、p53状态和干扰素信号对胶质母细胞瘤细胞对辐射和替莫唑胺治疗的反应的影响 Berezovsky, Artem; Nuga, Oluwademilade; Datta, Indrani; Bergman, Kimberly; Sabedot, Thais; Gurdziel, Katherine; Irtenkauf, Susan; Hasselbach, Laura; Meng, Yuling; Mueller, Claudius; Petricoin III, Emanuel F.; Brown, Stephen; Purandare, Neeraja; Aras, Sidhesh; Mikkelsen, Tom; Poisson, Laila; Noushmehr, Houtan; Ruden, Douglas; Decarvalho, Ana C. 分享 收藏
Targeted Dynamic Phospho-Proteogenomic Analysis of Gastric Cancer Cells Suggests Host Immunity Provides Survival Benefit 胃癌细胞的靶向动态磷酸化蛋白质组学分析表明宿主免疫可提供生存益处 Kume, Kohei; Iida, Midori; Iwaya, Takeshi; Yashima-Abo, Akiko; Koizumi, Yuka; Endo, Akari; Wade, Kaitlin; Hiraki, Hayato; Calvert, Valerie; Wulfkuhle, Julia; Espina, Virginia; Siwak, Doris R.; Lu, Yiling; Takemoto, Kazuhiro; Suzuki, Yutaka; Sasaki, Yasushi; Tokino, Takashi; Petricoin Iii, Emanuel; Liotta, Lance A.; Mills, Gordon B.; Nishizuka, Satoshi S. 分享 收藏
Clinical and immune responses to neoadjuvant fulvestrant with or without enzalutamide in ER+/Her2- breast cancer Elias, Anthony D.; Staley, Alyse W.; Fornier, Monica; Vidal, Gregory A.; Alami, Vida; Sams, Sharon; Spoelstra, Nicole S.; Goodspeed, Andrew; Kabos, Peter; Diamond, Jennifer R.; Shagisultanova, Elena; Gallagher, Rosa I.; Wulfkuhle, Julia D.; Petricoin, Emanuel F.; Zolman, Kathryn L.; McSpadden, Tessa; Jordan, Kimberly R.; Slansky, Jill E.; Borges, Virginia F.; Gao, Dexiang; Richer, Jennifer K. 分享 收藏
Elucidation of metabolic resistance mechanisms to RAS inhibition DeLiberty, Jonathan M.; Robb, Ryan; Roach, Mallory K.; Ackermann, Sarah E.; Yang, Runying; Pieper, Noah L.; Taylor, Khalilah E.; Bang, Scott; Baldelli, Elisa; Petricoin, Emanuel F., III; Morris, John P.; Stalnecker, Clint A.; Bryant, Kirsten L. 分享 收藏
PDAC tumors from patients treated with combination MEK and autophagy inhibition reveal a treatment sensitive epithelial subtype that is enriched in murine models Labadie, Brian W.; Obradovic, Aleksandar Z.; Ana, Sarah Sta; May, Michael; Sender, Naomi; Ross, Isabelle V.; Rodriguez-Mendez, Monica; Wasko, Urszula; Tomassoni, Lorenzo; Li, Li; Vij, Manan; Abuzaid, Sinan; Wulfkuhle, Julia; Wong, Winston; Pellicciotta, Ilenia; Izar, Benjamin; Petricoin, Emanuel F.; Tan, Aik Choon; Olive, Kenneth P.; Raufi, Alex G.; Manji, Gulam A. 分享 收藏
Signaling dynamics in coexisting monoclonal cell subpopulations unveil mechanisms of resistance to anti-cancer compounds Blanchard, Claire E.; Gomeiz, Alison T.; Avery, Kyle; El Gazzah, Emna; Alsubaie, Abduljalil M.; Sikaroodi, Masoumeh; Chiari, Ylenia; Ward, Chelsea; Sanchez, Jonathan; Espina, Virginia; Petricoin, Emanuel; Baldelli, Elisa; Pierobon, Mariaelena 分享 收藏
Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities (vol 8, 68, 2024) 富集HGSOC肿瘤上皮的蛋白质基因组分析确定预后特征和治疗弱点 (vol 8，68，2024) Bateman, Nicholas W.; Abulez, Tamara; Soltis, Anthony R.; McPherson, Andrew; Choi, Seongmin; Garsed, Dale W.; Pandey, Ahwan; Tian, Chunqiao; Hood, Brian L.; Conrads, Kelly A.; Teng, Pang-ning; Oliver, Julie; Gist, Glenn; Mitchell, Dave; Litzi, Tracy J.; Tarney, Christopher M.; Crothers, Barbara A.; Mhawech-Fauceglia, Paulette; Dalgard, Clifton L.; Wilkerson, Matthew D.; Pierobon, Mariaelena; Petricoin, Emanuel F.; Yan, Chunhua; Meerzaman, Daoud; Bodelon, Clara; Wentzensen, Nicolas; Lee, Jerry S. H.; Huntsman, David G.; Shah, Sohrab; Shriver, Craig D.; Phippen, Neil T.; Darcy, Kathleen M.; Bowtell, David D. L.; Conrads, Thomas P.; Maxwell, G. Larry 分享 收藏
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Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities 富集HGSOC肿瘤上皮的蛋白质基因组分析确定预后特征和治疗脆弱性 Bateman, Nicholas W.; Abulez, Tamara; Soltis, Anthony R.; Mcpherson, Andrew; Choi, Seongmin; Garsed, Dale W.; Pandey, Ahwan; Tian, Chunqiao; Hood, Brian L.; Conrads, Kelly A.; Teng, Pang-ning; Oliver, Julie; Gist, Glenn; Mitchell, Dave; Litzi, Tracy J.; Tarney, Christopher M.; Crothers, Barbara A.; Mhawech-Fauceglia, Paulette; Dalgard, Clifton L.; Wilkerson, Matthew D.; Pierobon, Mariaelena; Petricoin, Emanuel F.; Yan, Chunhua; Meerzaman, Daoud; Bodelon, Clara; Wentzensen, Nicolas; Lee, Jerry S. H.; Huntsman, David G.; Shah, Sohrab; Shriver, Craig D.; Phippen, Neil T.; Darcy, Kathleen M.; Bowtell, David D. L.; Conrads, Thomas P.; Maxwell, G. Larry 分享 收藏
p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs Grit, Jamie L.; Mcgee, Lauren E.; Tovar, Elizabeth A.; Essenburg, Curt J.; Wolfrum, Emily; Beddows, Ian; Williams, Kaitlin; Sheridan, Rachael T. C.; Schipper, Joshua L.; Adams, Marie; Arumugam, Menusha; Vander Woude, Thomas; Gurunathan, Sharavana; Field, Jeffrey M.; Wulfkuhle, Julia; Petricoin, Emanuel F.; Graveel, Carrie R.; Steensma, Matthew R. 分享 收藏
Multiomic-Based Molecular Landscape of FaDu Xenograft Tumors in Mice after a Combinatorial Treatment with Radiation and an HSP90 Inhibitor Identifies Adaptation-Induced Targets of Resistance and Therapeutic Intervention Bylicky, Michelle A.; Shankavaram, Uma; Aryankalayil, Molykutty J.; Chopra, Sunita; Naz, Sarwat; Sowers, Anastasia L.; Choudhuri, Rajani; Calvert, Valerie; Petricoin, Emanuel F.; Eke, Iris; Mitchell, James B.; Coleman, C. Norman 分享 收藏
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RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling Schaefer, Antje; Hodge, Richard G.; Zhang, Haisheng; Hobbs, G. Aaron; Dilly, Julien; Huynh, Minh V.; Goodwin, Craig M.; Zhang, Feifei; Diehl, J. Nathaniel; Pierobon, Mariaelena; Baldelli, Elisa; Javaid, Sehrish; Guthrie, Karson; Rashid, Naim U.; Petricoin, Emanuel F.; Cox, Adrienne D.; Hahn, William C.; Aguirre, Andrew J.; Bass, Adam J.; Der, Channing J. 分享 收藏
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Hexyl-(cuban-1-yl-methyl)-biguanide (HCB) suppresses N-glycosylation of immune checkpoint proteins B7-H3 and B7-H4, reverses tumor hypoxia, decreases intratumoral regulatory T cells, and increases intratumoral CD8+T cells in the ovarian dependent ER+HER2-SSM2ucd mammary cancer allograft model Guo, Zhijun; Lei, Jianxun; Venkatesh, Hrishi; Owen, David; Bass, Adam; Cannon, Christine; McCarra, Joshua; Koniar, Brenda; Flory, Craig; Norris, Beverly; Schumacher, Robert J.; Jayaraman, Swaathi; Hawse, John; Antonarakis, Emmanuel S.; Petricoin, Emanuel F.; Wulfkuhle, Julia; Cardiff, Robert D.; Ambrose, Elizabeth A.; Georg, Gunda I.; Schwertfeger, Kaylee L.; Farrar, Michael A.; Croix, Brad St.; Goetz, Matthew P.; Potter, David A. 分享 收藏
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